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Three-Year Consecutive Field Application of Erythromycin Fermentation Residue Following Hydrothermal Treatment:Cumulative Effect on Soil Antibiotic Resistance Genes

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Engineering 2022年第8期8卷 78-88页

作者： Ziming Han Haodi Feng Xiao Luan Yunpeng Shen Liren Ren Liujie Deng D.G.Joakim Larsson Michael Gillings Yu Zhang Min Yang State Key Laboratory of environmental Aquatic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of sciences Beijing 100049China State environmental Protection Engineering Center for Harmless Treatment and Resource Utilization of Antibiotic Residues Khorgos 835007China institute for Biomedicine&the centre for Antibiotic Resistance Research University of GothenburgGoteborg SE-41346Sweden Australian Research Council(ARC)centre of Excellence in Synthetic Biology Department of Biological SciencesFaculty of Science and EngineeringMacquarie UniversitySydneyNSW 2109Australia

Fermentation-based antibiotic production results in abundant nutrient-rich fermentation residue with high potential for recycling,but the high antibiotic residual concentration restricts its usefulness(e.g.,in land application as organic fertilizer).In this study,an industrial-scale hydrothermal facility for the treatment of erythromycin fermentation residue(EFR)was investigated,and the potential risk of the long-term soil application of treated EFR promoting environmental antibiotic resistance development was *** treatment effectively removed bacteria and their DNA,and an erythromycin removal ratio of up to approximately 98%was *** treated EFR was utilized as organic fertilizer for consecutive field applications from 2018 to 2020,with dosages ranging from 3750 to 15000 kg·hm^(-2),resulting in subinhibitory levels of erythromycin(ranging from 0.83-76.00μg·kg^(-1))in *** shotgun sequencing was then used to characterize the antibiotic resistance genes(ARGs),mobile genetic elements(MGEs),and bacterial community composition of the *** soil ARG abundance and diversity did not respond to the treated EFR application in the first year,but gradually changed in the second and third year of *** highest fold change in relative abundance of macrolide-lincosamide-streptogramin(MLS)and total ARGs were 12.59 and 2.75 times,compared with the control(CK;without application),*** soil MGEs and taxonomic composition showed similar temporal trends to those of the ARGs,and appeared to assist in driving increasing ARG proliferation,as revealed by correlation analysis and structural equation models(SEMs).The relative abundance of particular erm resistance genes(RNA methyltransferase genes)increased significantly in the third year of treated EFR *** close association of erm with MGEs suggested that horizontal gene transfer played a critical role in the observed erm gene *** binning results demonstr

关键词： Pharmaceutical manufacturing Resistome Antibiotic Risk assessment Remediation Land application

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Ameliorating impaired cardiac function in myocardial infarction using exosome-loaded gallic-acid-containing polyurethane scaffolds

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Bioactive Materials 2024年第3期33卷 324-340页

作者： Ankita Das Aman Nikhil Parvaiz Ahmad Shiekh Babita Yadav Kumaravelu Jagavelu Ashok Kumar Department of Biological sciences and Bioengineering Indian Institute of Technology KanpurKanpur208016U.P.India SMART Lab Centre for Biomedical EngineeringIndian Institute of Technology DelhiHauz KhasNew Delhi 110016India Department of Pharmacology Council of Scientific and Industrial Research(CSIR)-Central Drug Research InstituteLucknow226031U.P.India centre for environmental sciences and Engineering Indian Institute of Technology KanpurKanpur208016U.P.India centre of Excellence for Orthopaedics and Prosthetics Gangwal School of Medical Sciences and TechnologyIndian Institute of Technology KanpurKanpur208016U.P.India The Mehta Family centre for Engineering in Medicine Indian Institute of Technology KanpurKanpur208016U.P.India Department of Biological sciences and Bioengineering Indian Institute of Technology KanpurKanpur208016U.P.India.

Myocardial infarction(MI)can be tackled by implanting cardiac patches which provide mechanical support to the ***,most tissue-engineered scaffolds face difficulty in attenuating oxidative stress,maintaining mechanical stability,and regenerating damaged ***,we fabricated elastic cryogels using polyurethane modified with antioxidant gallic acid in its backbone(PUGA)and further coated them with decellularized extracellular matrix(dECM)to improve adhesiveness,biocompatibility and *** scaffold was functionalized with exosomes(EXO)isolated from adipose-derived stem cells having regenerative ***-dECM+EXO was tested in a rat model with induced MI where echocardiography after 8 weeks of implantation showed significant recovery in treatment *** analysis revealed a decrease in fibrosis after application of patch and promotion of angiogenesis with reduced oxidative stress was shown by *** of cardiac tissue contractile function marker was also observed in treatment ***,the proposed biomaterial has a promising application to be utilized as a patch for cardiac *** detailed studies with larger animal species are needed for using these observations for specific applications.

关键词： Antioxidant Polyurethane Gallic acid Myocardial infarction Cardiac regeneration

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In situ calcite U-Pb geochronology by high-sensitivity single-collector LA-SF-ICP-MS

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science China Earth sciences 2022年第6期65卷 1146-1160页

作者： Shitou WU Yueheng YANG Nick M.W.ROBERTS Ming YANG Hao WANG Zhongwu LAN Bohang XIE Tianyi LI Lei XU Chao HUANG Liewen XIE Jinhui YANG Fuyuan WU State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Innovation Academy for Earth science Chinese Academy of SciencesBeijing 100029China Geochronology and Tracers Facility British Geological SurveyEnvironmental Science CentreNottinghamNG125GGUK Key Laboratory of Deep Geology and Resources SinopecBeijing 102206China

U-Pb geochronology of calcite using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) is an emerging method,with potential applications to a vast array of geological *** to the low levels of U and Pb in calcite,measurement using higher-sensitivity instruments,such as sector field (SF) ICP-MS,have advantages over more commonly used quadrupole (Q) ICP-MS *** a Thermo Element XR ICP-MS,we demonstrate that the Jet+X cone combination with the N_(2) enhancement technique provides the best sensitivity for measuring U and Pb *** higher sensitivity improves the precision of calcite U-Pb isotope measurements,and permits dating at high spatial resolutions (<110μm) and for samples containing low contents of^(238)U (<1μg g^(–1)) and/or^(207)Pb (i.e.,young samples<10 Ma).Using a spot size of 85μm with a low fluence (~2.0 J cm^(–2)),the laser-induced elemental fractionation of^(206)Pb/^(238)U in the NIST SRM 614,ARM-3 and WC-1 reference materials are insignificant (<2.2%).Adopting the optimized instrument parameters,we analysed four commonly-used calcite U-Pb reference materials (WC-1,Duff Brown Tank,JT,and ASH-15).The results match well with published isotope dilution data,demonstrating the reliability of our ***-3,an andesitic glass,is shown to be an appropriate reference material for both^(207)Pb/^(206)Pb calibration and instrument optimization because of its moderate contents of U(~3.75μg g^(–1)) and Pb (~12.7μg g^(–1)).We further demonstrate that the image-guided approach using LA-ICP-MS elemental mapping is an efficient tool in obtaining robust ages.

关键词： Calcite U-Pb geochronology SF-ICP-MS LA-ICP-MS Sensitivity enhancement Jet sample cones

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Catalytic transfer hydrogenolysis of C–O bonds in lignin model compounds without arene hydrogenation

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Green Chemical Engineering 2022年第1期3卷 25-33页

作者： Kai Cui Xiuge Zhao Qingpo Peng Honghui Gong Xinjia Wei Jiajia Wang Manyu Chen Zhenshan Hou Key Laboratory for Advanced Materials Research Institute of Industrial CatalysisSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai200237China

The shortage of resources and the destruction of the environment have caused serious resource and environmental problems shared by all countries around the world. As a ubiquitous renewable resource, biomass has great prospects for replacing fossil energy and attracted attention from the society. The use of catalytic approach to transform biomass into high-value chemicals is an effective way to use biomass efficiently. In this work, Nisupported catalysts has been developed for the selective cleavage of C–O bonds in lignin model compounds with 2-propanol as the hydrogen source solvent. Among these catalysts, it was indicated that zirconium phosphate(Zr P)-supported Ni catalysts were highly efficient and recyclable for alkyl-aryl ether(α-O-4 and β-O-4) cleavage in lignin model compounds. The further investigation demonstrated that the transfer hydrogenolysis of the C–O bond is highly selective, which afforded phenols and aromatics as dominant products without the products arising from hydrogenation of aromatic rings. Through a series of characterization of the catalyst, it was demonstrated that the medium strong acid sites of the Zr P support promoted the cleavage of alkyl-aryl ethers(α-O-4 and β-O-4),and Br?nsted acid sites favored for achieving high selectivity toward C–O bond cleavage. Additionally, Ni(0) sites on the Zr P catalysts were responsible for the catalytic transfer hydrogenolysis.

关键词： C–O bond cleavage Hydrogenolysis Zirconium phosphate Biomass conversion Ni catalysts

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Effects of Biochar on the Abundance of Three Agriculturally Important Soil Bacteria

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Journal of Agricultural Chemistry and Environment 2014年第2期3卷 31-39页

作者： Tazeen Fatima Khan Monzur Morshed Ahmed Shah Muhammad Imamul Huq Bangladesh-Australia centre for environmental Research (BACER-DU) Department of Soil Water and Environment University of Dhaka Dhaka Bangladesh industrial Microbiology Laboratory Institute of Food Science and Technology (IFST) Bangladesh Council of Scientific and Industrial Research Dhaka Bangladesh

An in vitro study was conducted to make a comparative study of biochar and biomass on soil bacteria. The responses of three agriculturally important bacteria viz., Bradyrhizobium, Sulphate reducing and Iron oxidizing bacteria, were studied. Total viable counts were also made. Three different types of biomasses viz., rice husk, rice straw and saw dust, and biochars produced thereof were used for the study. The biomasses or biochars were applied to the soil at a rate of 5 t/ha. The study included seven different treatments of biomasses and corresponding biochars including a control. Total counts were made on the original materials as well as on the treated soils at 30, 60 and 90 days of incubation. Bacterial count was higher in all the biomass treated soils than the corresponding biochar treated ones including control. Although the presence of Bradyrhizobium, sulphate reducing and iron oxidizing bacteria were not noted in the fresh soils, their presence, however, was noted after incubation periods. The counts of all three bacteria are however lower in the biochar treated soils than the corresponding biomass treated soils. The paper discusses about the microbial soil health vis-à-vis biochar application, indicating that the materials exert negative effect on the soil microbial population and thereby likely to jeopardize soil health and crop production.

关键词： Biochar Bradyrhizobium Incubation Soil Health

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In vitro corrosion properties of HTHEed Mg-Zn-Y-Nd alloy microtubes for stent applications:Influence of second phase particles and crystal orientation

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Journal of Magnesium and Alloys 2022年第5期10卷 1286-1295页

作者： Peihua Du Di Mei Tsuyoshi Furushima Shijie Zhu Liguo Wang Yifan Zhou Shaokang Guan School of Materials science and Engineering Zhengzhou UniversityZhengzhou 450001China Henan Key Laboratory of Advanced magnesium Alloys Zhengzhou 450002China Key Laboratory of Advanced Materials Processing and Mold Ministry of Education Zhengzhou 450002China Department of Mechanical and Biofunctional Systems Institute of Industrial ScienceThe University of Tokyo4-6-1KomabaMeguroTokyo 153-8505Japan Magnesium Innovation centre-MagIC Institute of Materials ResearchHelmholtz-Zentrum GeesthachtGeesthacht 21502Germany

Magnesium(Mg)alloys are promising materials for cardiovascular stent applications due to their good biocompatibility and ***,in vitro and in vivo corrosion tests reveal that Mg alloy stents suffer from a rapid corrosion rate and severe localized corrosion,which is limiting their widespread *** solve the problem of uneven degradation of stents,a HTHE(long-time and high-temperature heat treatment,large-reduction-ratio hot extrusion)process is used to manufacture Mg-Zn-Y-Nd alloy microtubes in this *** heat treatment is to dissolve alloying elements and reduce the size of SPPs,and the hot extrusion is to acquire fine-grained and strongly textured *** microstructural characterization shows that coarse second phases in as-cast alloy are refined and uniformly distributed in matrix of *** hot extrusion,microtubes show strong texture with basal plain oriented parallel to the longitudinal section(LS).The corrosion testing indicates that severe localized corrosion occurs on the cross section(CS)while localized corrosion is alleviated on the *** on the different corrosion properties of the LS and CS,HTHEed microtubes are promising for solving the problems of rapid corrosion rate and severe localized corrosion of Mg alloy stents.

关键词： Mg-Zn-Y-Nd alloy Microtubes Heat treatment Hot extrusion Corrosion properties Cardiovascular stent

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A Review on Swarm Intelligence and Evolutionary Algorithms for Solving Flexible Job Shop Scheduling problems

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IEEE/CAA Journal of Automatica Sinica 2019年第4期6卷 904-916页

作者： Kaizhou Gao Zhiguang Cao Le Zhang Zhenghua Chen Yuyan Han Quanke Pan IEEE the Macao institute of Systems Engineering at Macao University of science and Technology 999078 China School of Computer at Liaocheng Univeristy Liaocheng252059China the Department of industrial Systems Engineering and Management National University of SingaporeSingapore centre for Maritime Studies National University of SingaporeSingapore the institute for Infocomm Research(I2R) the Agency for ScienceTechnology and Research(A*STAR)Singapore the School of Computer at Liaocheng Univeristy Liaocheng 252059China School of Mechatronic Engineering and Automation Shanghai UniversityShanghai 200072China

Flexible job shop scheduling problems(FJSP)have received much attention from academia and industry for many *** to their exponential complexity,swarm intelligence(SI)and evolutionary algorithms(EA)are developed,employed and improved for solving *** than 60%of the publications are related to SI and *** paper intents to give a comprehensive literature review of SI and EA for solving ***,the mathematical model of FJSP is presented and the constraints in applications are ***,the encoding and decoding strategies for connecting the problem and algorithms are *** strategies for initializing algorithms?population and local search operators for improving convergence performance are ***,one classical hybrid genetic algorithm(GA)and one newest imperialist competitive algorithm(ICA)with variables neighborhood search(VNS)for solving FJSP are ***,we summarize,discus and analyze the status of SI and EA for solving FJSP and give insight into future research directions.

关键词： Evolutionary algorithm flexible job shop scheduling review swarm intelligence

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Perfluorooctane sulfonate(PFOS) and related fluorochemicals in chicken egg in China

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Chinese science Bulletin 2008年第4期53卷 501-507页

作者： WANG Yuan YEUNG Leo Wai Yin YAMASHITA Nobuyoshi TANIYASU Sachi SO Man Ka Margaret B. MURPHY LAM Paul Kwan Sing centre for Coastal Pollution and Conservation Department of Biology and Chemistry City University of Hong Kong 83 Tat Chee Avenue Kowloon Tong HKSAR China National institute of Advanced industrial science and Technology (AIST) 16-10nogawa Tsukuba Ibaraki 305-8569 Japan

The ubiquitous occurrence of perfluorinated compounds(PFCs) in environmental samples has drawn much *** human exposure studies found relatively high perfluorooctane sulfonate(PFOS) concentrations in blood samples from several cities in China when compared with other *** objectives of the present study were:(1) to measure PFC concentrations and compositions in chicken egg samples from local markets in China;and(2) to conduct a preliminary human health risk assessment of egg *** pooled egg samples from eight locations were analyzed for 11 *** results showed that close to 100% of the PFOS in the egg was distributed in egg yolk and PFOS was not detected in egg white(<0.08 ng/g wet weight,w/w).Of the perfluoroalkylsulfonates,only PFOS was detected in all egg samples,while of the perfluoroalkylcarboxylates,perfluoroundecanoic acid(PFUnDA) was detected in all samples,followed by perfluorooctanoate(PFOA)(75% occurrence) and perfluorodecanoic acid(PFDA)(50% occurrence).PFOS concentrations in egg ranged from 45.0 to 86.9 ng/g w/*** results suggested that current concentrations of PFOS in domestic chicken eggs are unlikely to cause immediate harm to Chinese populations.

关键词：中国鸡蛋人体健康风险评估污染物含氟化合物全氟辛烷磺酸

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Predicting the Risk of Arterial Stiffness in Coal Miners Based on Different Machine Learning Models

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Biomedical and environmental sciences 2024年第1期37卷 108-111页

作者： CHEN Qian Wei HUANG Xue Zan DING Yu ZHU Feng Ren WANG Jia ZOU Yuan Jie DU Yuan Zhen ZHANG Ya Jun HUI Zi Wen ZHU Feng Lin MU Min The Project was supported by Open Research Grant of Joint National-Local Engineering Research centre for Safe and Precise Coal Mining Anhui University of Science and TechnologyHefei 232001AnhuiChina School of Public Health Anhui University of Science and TechnologyHefei 232001AnhuiChina Key Laboratory of industrial Dust Prevention and Control Occupational Safety and HealthMinistry of EducationAnhui University of Science and TechnologyHefei 232001AnhuiChina Anhui institute of Occupational Safety and Health Anhui University of Science and TechnologyHefei 232001AnhuiChina Joint Research Center of Occupational Medicine and Health Institute of Grand HealthHefei Comprehensive National Science CenterAnhui University of Science and TechnologyHefei 232001AnhuiChina Department of Occupational&environmental Health School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030HubeiChina Key Laboratory of Environment and Health Ministry of Education&Ministry of Environmental Protectionand State Key Laboratory of Environmental Health(Incubating)School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030HubeiChina

Coal is one of the world’s main energy resources,accounting for approximately 68%of China’s current total power ***,several studies have demonstrated that dust,exhaust fumes,and other harmful factors in coal mines increase the risk of cardiovascular disease(CVD)among miners^([1]).Arterial stiffness(AS)is an independent risk factor of CVD,and epidemiological studies have shown that AS plays a vital role in assessing the risk of CVD^([2]).

关键词： Arterial cardiovascular assessing

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Effect of tin addition on corrosion behavior of a low-alloy steel in simulated costal-industrial atmosphere

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Journal of Materials science & Technology 2019年第7期35卷 1228-1239页

作者： Bo Liu Xin Mu Ying Yang Long Hao Xueyong Ding Junhua Dong Zhe Zhang Huaxing Hou Wei Ke School of Metallurgy Northeastern UniversityShenyang 110819China environmental Corrosion Research centre of Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Ansteel Co. Ltd.Anshan 114021China

The effect of tin addition on the atmospheric corrosion behavior of a low-alloy steel in sim ulated coastalindustrial atm osphere has been investigated by indoor wet/dry cyclic corrosion test (CCT). The results indicate that tin addition can obviously make the steel substrate more resistant to atmospheric corrosion by suppressing the cathodic H^+ reduction reaction, and but tin addition is not of obvious beneficial effect when the steel is covered with a thicker rust layer during long-term corrosion process. The reason lies in the fact that the presence of un-reduced H^+ can lower the electrolyte pH value and lead to a loose and porous rust layer on tin-containing steel sample than that on tin-free steel sample. In addition, the 120 CCT cycles corrosion process of the two steels can be divided into three stages. Both the tin-free and tin-containing steels show an increasing corrosion rate during the initial corrosion stage and then exhibit a decreasing corrosion rate during the second and third corrosion stages. Moreover, tin addition makes the tin-containing steel rust layer have a higher amount of α-FeOOH and lower am ount of γ-FeOOH and Fe3O4 than the tin-free steel rust layer.

关键词： Weathering steel Atmospheric corrosion Coastal-industrial atmosphere Tin addition Rusting evolution

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