检索结果-南通市图书馆

Chinese Chemical Letters 2024年第4期35卷 321-323页

作者： Lixian Fu Yiyun Tan Yue Ding Weixia Qing Yong Wang henan international joint laboratory of medicinal plants utilization College of Chemistry and Molecular SciencesHenan UniversityKaifeng 475004China School of Basic Medical Science Henan UniversityKaifeng 475004China

A novel D–π –A structure and near–infrared fluorescent probe(DCITT) with high polarity sensitivity and membrane targeting was reported. The fluorescent spectra of DCITT were polarity dependent and Stokes shift was greater than 300 nm. Due to its high fluorescence quantum yield, low cytotoxicity and photostability, DCITT could be used as a labeling probe in multicellular organisms. In particular, DCITT effectively distinguished tumor cells from normal cells because it could specifically light up the cancer cells membrane based on strong red fluorescence for a long time. On this basis, a polar–sensitive cell membrane probe is developed to differentiate tumor cells from normal cells, which provides an idea and method for the early diagnosis of tumor at cellular level.

关键词： NIR–fluorescent probe Polarity–sensitive Bioimaging Targeting cell membrane Differentiate tumor and normal cells

An allelic variation in the promoter of the LRR-RLK gene, qSS6.1, is associated with melon seed size

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第10期 3522-3536页

作者： Xiaoxue Liang Jiyu Wang Lei Cao Xuanyu Du Junhao Qiang Wenlong Li Panqiao Wang Juan Hou Xiang Li Wenwen Mao Huayu Zhu Luming Yang Qiong Li Jianbin Hu College of Horticulture Henan Agricultural University henan Engineering Research Center for Cucurbit Germplasm Enhancement and utilization international joint laboratory of henan Horticultural Crop Biology

Seed size is an important agronomic trait in melons that directly affects seed germination and subsequent seedling ***, the genetic mechanism underlying seed size in melon remains *** the present study,we employed Bulked-Segregant Analysis sequencing （BSA-seq） to identify a candidate region （～1.35 Mb） on chromosome 6 that corresponds to seed *** interval was confirmed by QTL mapping of three seed sizerelated traits from an F2population across three *** mapping region represented nine QTLs that shared an overlapping region on chromosome 6, collectively referred to as *** InDel markers were developedintheqSS6.1 region, narrowing it down to a 68.35 kb interval that contains *** variation analysis of the eight genes identified a SNP with a C to T transition mutation in the promoter region of MELO3C014002, a leucine-rich repeat receptor-like kinase （LRR-RLK） *** mutation affected the promoter activity of the MELO3C014002 gene and was successfully used to differentiate the large-seeded accessions （C-allele） from the small-seeded accessions （T-allele）.qRT-PCR revealed differential expression of MELO3C014002 between the two parental *** predicted protein has typical LRR-RLK family domains, and phylogenetica***, these findings suggest MELO3C014002 as the most likely candidate gene involved in melon seed size *** results will be helpful for better understanding the genetic mechanism regulating seed size in melons and for genetically improving this important trait through molecular breeding pathways.

关键词：

Identification of an Aux/IAA regulator for flesh firmness using combined GWAS and bulked segregant RNA-Seq analysis in watermelon

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Horticultural Plant Journal 2024年第5期10卷 1198-1213页

作者： Muhammad Anees Hongju Zhu Muhammad Jawad Umer Chengsheng Gong Pingli Yuan Xuqiang Lu Nan He Mohamed Omar Kaseb Dongdong Yang Yong Zhao Wenge Liu henan joint international Research laboratory of South Asian Fruits and Cucurbits Zhengzhou Fruit Research InstituteChinese Academy of Agricultural SciencesZhengzhouHenan 450009China henan Key laboratory of Fruit and Cucurbit Biology Zhengzhou Fruit Research InstituteChinese Academy of Agricultural SciencesZhengzhouHenan 450009China State Key laboratory of Cotton Biology Institute of Cotton ResearchChinese Academy of Agricultural Science(ICRCAAS)AnyangHenan 455000China National Key laboratory for Germplasm Innovation&utilization of Horticultural Crops Zhengzhou Fruit Research InstituteChinese Academy of Agricultural SciencesZhengzhouHenan 450009China

Watermelon is a highly cultivated fruit crop renowned for its quality properties of fruit *** various quality factors,fruit flesh firmness is a crucial quality parameter influencing the fruit texture,shelf life and its commercial *** auxin/indole-3-acetic acid(Aux/IAA)plays a significant role in fruit development and ripening of non-climacteric ***,the regulatory mechanism of Aux/IAA in controlling fruit flesh firmness and ripening in watermelon remains *** this study,we employed an integrative approach combining genome-wide association study(GWAS)and bulked segregant RNA-Seq analysis(BSR-Seq)to identify an overlapping candidate region between 12776310 and 12968331 bp on chromosome 6,underlying an auxin-responsive gene(Aux/IAA)associated with flesh firmness in *** analysis,followed by real-time quantitative reverse transcription PCR(qRT-PCR),confirmed that the expression of Aux/IAA was consistently higher in fruits with high flesh *** sequence alignment revealed a single base mutation in the coding region of Aux/***,the concomitant Kompetitive/Competitive allele-specific PCR(KASP)genotyping data sets for F2 population and germplasm accessions identified Aux/IAA as a strong candidate gene associated with flesh ***/IAA was enriched in the plant hormone signal transduction pathway,involving cell enlargement and leading to low flesh *** determined the higher accumulation of abscisic acid(ABA)in fruits with low flesh firmness than hard ***,overexpression of Aux/IAA induced higher flesh firmness with an increased number of fruit flesh cells while reducing ABA content and flesh cell ***,the allelic variation in Aux/IAA for soft flesh firmness was found to exist in Citrullus mucosospermus and gradually fixed into Citrullus lanatus during domestication,indicating that soft flesh firmness was a domesticated *** findings significantly enhanced our unders

关键词： Watermelon Flesh firmness GWAS BSR-Seq KASP marker analysis Transient overexpression

A review:the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

未来食品学报(英文) 2024年第3期4卷 183-192页

作者： Mengjie Ren Adel F.Ahmed Meng Li Menghan Li Zhiruo Yan Jinmei Wang National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China joint international Research laboratory of Food&Medicine Resource Function Henan ProvinceKaifeng 475004China medicinal and Aromatic plants Researches Department Horticulture Research InstituteAgricultural Research CenterGiza 12511Egypt

Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk,leading to the *** and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts,exerting anti-osteoporosis *** to the previous research,the extract of Cibotium barumoz,Achyranthes bidentata,Curculigo orchioides,Epimedium brevicornum,Angelica sinensis,Polygonatum sibiricum,Dendrobium officinale,Morinda officinalis,Nelumbo mucifera,Diospyros kaki,Hordeum vulgare,Cistanche deserticola,Commiphora Myrrha and other plant-derived polysaccharides could benefit to the osteoblasts and *** essential mechanisms are mainly related to the activation or inhibition of many factors,including runt-related transcription factor 2(Runx2),B-catenin,osterix(Osx),activator protein-1(AP-1),osteocalcin(OCN/BGP),alkaline phosphatase(ALP),osteopontin(OPN),bone morphogenetic protein(BMP),phosphatidylinositol 3-kinase(PI3K)/C-Jun N-terminal kinase(JNK)/extracellular regulated protein kinase(ERK),osteoprotegerin(OPG),receptor activator of nuclear factor-kB(RANK),monocyte/macrophage colony-stimulating factor(M-CSF),tumor necrosis factor receptor-associated factor 6(TRAF-6),receptor activator of nuclear factor(NF)-KB ligand(RANKL),nuclear factor of activated T cells 1(NFATc1),c-Fos,matrix metallopeptidase-9(MMP-9),glycogen synthase kinase 3β(GSK3B)/B-catenin,nuclear factor E2-related factor 2(Nf2),as well as these related pathways,such as Wnt/p-catenin,BMP-2/SMAD1/5/8,PI3K/AKT,OPG/RANKL/RANK,NF-κB,MAPKs,*** plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its *** reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.

关键词： Osteoporosis Plant-derived polysaccharides Osteogenesis promotion Osteoclasts inhibition

Selenium Regulates Antioxidant Capacities and Diterpenoid Biosynthesis in the medicinal Plant Isodon rubescens

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phyton-international Journal of Experimental Botany 2024年第7期93卷 1705-1716页

作者： Fenglan Zhao Shuwen Wu Xue Meng Jianping Xue Yongbo Duan Anhui Provincial Engineering laboratory for Efficient utilization of Featured Resource plants College of Life SciencesHuaibei Normal UniversityHuaibei235000China Huaibei Key laboratory of Efficient Cultivation and utilization of Resource plants College of Life SciencesHuaibei Normal UniversityHuaibei235000China

Dōng líng căo,the dried aboveground parts of Isodon rubescens(Hemls.)Hara.,is commonly consumed as a med-icinal decoction or tea *** beverages can be an important source of human dietary selenium(Se).However,how *** plants respond to exogenous Se remains *** this study,a pot cultivation experiment was employed to investigate the phenotypic and physiological responses of *** plants exposed to *** days after applying different concentrations of sodium selenate to the soil,the Se enrichment capa-city,growth indices,antioxidant capacities,and the content ofﬂavonoids and diterpenoids were measured in the ***,the oridonin content was quantiﬁed using the high-performance liquid chromatography method,and the expression levels of key diterpenoid synthesis genes were analyzed by quantitative real-time PCR(qRT-PCR).*** plants efﬁciently accumulated Se,with the Se content increasing proportionally to the applied dose,reaching levels of nearly 200 mg·kg^(-1) dry leaves as Se concentration *** of the three Se treat-ments signiﬁcantly altered the phenotypic indices,except a longer root length occurred in the 3μM·kg^(-1) Se *** three Se doses,6μM·kg^(-1) Se gave the highest accumulation ofﬂavonoids,diterpenoids,and oridonin,with the increase of 2.0-,1.8-,and 1.9-fold in aboveground parts,*** application boosted the activities of antioxidant enzymes and antioxidant capacities according to 2,2-Diphenyl-1-picrylhydrazyl(DPPH),ferric reducing/antioxidant power,and tea brewing color *** key synthase genes were upregulated signiﬁcantly by 6μM·kg^(-1) Se treatment,notably 1-deoxy-D-xylulose 5-phosphate reductoisomerase(IrDXR),with a 5-fold increase,and kaurene synthase-like 4(IrKSL4),with a 6-fold ***,Se application in *** cultivation may be a potential biofortiﬁcation method to supplement Se while increasingﬂavonoid and diterpenoid contents.

关键词： Flavonoids oridonin physiological indicators quantitative real-time PCR selenium

Constructing Al@C-Sn pellet anode without passivation layer for lithium-ion battery

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

international Journal of Minerals,Metallurgy and Materials 2024年第3期31卷 552-561页

作者： Kangzhe Cao Sitian Wang Yanan He Jiahui Ma Ziwei Yue Huiqiao Liu College of Chemistry and Chemical Engineering Xinyang Normal UniversityXinyang 464000China Xinyang Key laboratory of Low-Carbon Energy Materials Xinyang 464000China henan Province Key laboratory of utilization of Non-Metallic Mineral in the South of henan Xinyang 464000China

Al is considered as a promising lithium-ion battery(LIBs)anode materials owing to its high theoretical capacity and appropri-ate lithation/de-lithation ***,its inevitable volume expansion causes the electrode structure instability,leading to poor cyclic ***’s worse,the natural Al2O3 layer on commercial Al pellets is always existed as a robust insulating barrier for elec-trons,which brings the voltage dip and results in low reversible ***,this work synthesized core-shell Al@C-Sn pellets for LIBs by a plus-minus *** this proposal,the natural Al2O3 passivation layer is eliminated when annealing the pre-introduced SnCl2,meanwhile,polydopamine-derived carbon is introduced as dual functional shell to liberate the fresh Al core from re-oxidization and alle-viate the volume *** from the addition of C-Sn shell and the elimination of the Al2O3 passivation layer,the as-prepared Al@C-Sn pellet electrode exhibits little voltage dip and delivers a reversible capacity of 1018.7 mAh·g^(-1) at 0.1 A·g^(-1) and 295.0 mAh·g^(-1) at 2.0 A·g^(-1)(after 1000 cycles),***,its diffusion-controlled capacity is muchly improved compared to those of its counterparts,confirming the well-designed nanostructure contributes to the rapid Li-ion diffusion and further enhances the lithium storage activity.

关键词： lithium-ion battery high-performance anode aluminum passivation layer plus-minus strategy

Photoelectrochemical seawater oxidation with metal oxide materials:Challenges and opportunities

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第10期97卷 767-782页

作者： Miao Kan Hangyu Hu Weijie Zhuang Meng Tao Shiqun Wu Jinlong Zhang Key laboratory for Advanced Materials and joint international Research laboratory of Precision Chemistry and Molecular Engineering Feringa Nobel Prize Scientist Joint Research Center School of Chemistry and Molecular Engineering East China University of Science and Technology Shanghai Engineering Research Center for Multimedia Environmental Catalysis and Resource utilization East China University of Science and Technology

Photocatalytic water oxidation is a crucial counter-electrode reaction in the process of photoelectrochemical energy *** its importance,challenges remain in effectively and sustainably converting water to oxygen,particularly with readily available and inexpensive electrolyte solutions such as *** metal oxide materials have demonstrated their advantages in promoting efficiency by reducing overpotential and improving light utilization,stability remains limited by corrosion in multicomponent *** this paper,we reviewed the relationship between four basic concepts including photoelectrochemistry,metal oxide,water oxidation and seawater to better understand the challenges and opportunities in photoelectrochemical(PEC) seawater *** overcome these challenges,the advances in material design,interfacial modification,local environment control and reactor design have been further reviewed to benefit the industrial PEC seawater ***,we demonstrate engineered layered metal oxide electrodes and cell structures that enable powerful and stable seawater *** also outline and advise on the future direction in this area.

关键词： Photoelectrochemistry Anode Water oxidation Metal oxide Seawater Stability

Developing silicon-based photocathodes for CO_(2) conversion

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第6期67卷 1904-1921页

作者： Weijie Zhuang Miao Kan Tao Meng Jinlong Zhang Key laboratory for Advanced Materials and joint international Research laboratory of Precision Chemistry and Molecular Engineering Feringa Nobel Prize Scientist Joint Research CenterSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai200237China Shanghai Engineering Research Center for Multimedia Environmental Catalysis and Resource utilization East China University of Science and TechnologyShanghai200237China

Photoelectrochemical(PEC)conversion of CO_(2) presents a promising avenue for solar-driven chemical fuel production,with silicon emerging as a cost-effective and high-light-absorbing material pivotal to this *** at exploring opportunities for industrializing PEC CO_(2) reduction(PEC-CO_(2)R)by minimizing reaction energy consumption,enhancing reaction efficiency and selectivity,this review summarizes recent advancements in developing Si-based photocathodes for PEC-CO_(2)*** outlines the fundamental principles,advantages,and limitations of Si photocathodes with key performance *** on this understanding,the strategies to enhance the performance of the PEC-CO_(2)R system,including light absorption,charge separation,and catalytic reactions are categorized as the interfacial modification,active site decoration,and protective layer *** design ideas of this advantageous three-layer structure in promoting the efficiency,stability,and selectivity have been ***,this review scrutinizes the influence of the photocathodic chemical *** review consolidates the mechanism insights and notable breakthroughs of various fuel generation processes within Si-based PEC-CO_(2)R *** this wealth of information offers an up-to-date perspective on the dynamic developments in silicon-based PEC-CO_(2) conversion and underscores the promising pathways toward the sustainable fuel synthesis from pollutant CO_(2).

关键词： photoelectrochemistry solar fuels silicon photocathodes carbon dioxide reduction microenvironment

3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第3期13卷 1453-1464页

作者： Mengjie Liu Xuqiang Liu Kaiyue He Yongping Jian Yujia Li Jinrong Guo Jingyu Yang Zhixiang Xu Wenyi Kang School of Life Sciences Henan UniversityKaifeng 475004China National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China joint international Research laboratory of Food&Medicine Resource Function Kaifeng 475004China Shenzhen Research Institute of henan University Shenzhen 518000China

3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)is a pentacyclic triterpene mainly distributed in food and medicinal plants,which exhibits various pharmacological ***,whether these functions are attributed to eBAG or additional components in these plants remain ***,we report that eBAG exerted an inhibitory activity against hepatocellular carcinoma and esophageal cancer *** induced non-apoptotic cell death in hepatocellular carcinoma *** eBAG-induced cell death was inhibited by knock-down of autophagy related gene(ATG)5 and ATG7,by administration of 3-methyladenine,a selective autophagy inhibitor that suppresses phosphoinositide 3-kinase(PI3K),and by chloroquine,a classic autophagy flux *** demonstrated that eBAG induced an autophagy-mediated cell *** of eBAG mimicked cellular bioenergetics depletion leading to the reduction of intracellular ATP,activation of AMP-activated protein kinase(AMPK),and inhibition of ***-treatment with compound C,an AMPK inhibitor,abrogated cell death induced by *** further validated the anti-tumor effect of eBAG in the murine xenograft model of hepatocellular carcinoma and found that eBAG treatment promoted the induction of autophagy and reduction of tumor growth in *** a functional food ingredient,eBAG is a potential therapeutic agent for the treatment of hepatocellular carcinoma and esophageal cancer.

关键词： eBAG Autophagy ATP AMPK Hepatocellular carcinoma

Hematopoietic aging:Cellular,molecular,and related mechanisms

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2024年第11期137卷 1303-1312页

作者： Li Ye Chuan Tian Ye Li Hang Pan Jinxiu Hu Liping Shu Xinghua Pan The Stem Cells and Immune Cells Biomedical Techniques Integrated Engineering laboratory of State and Regions Cell Therapy Technology Transfer Medical Key Laboratory of Yunnan ProvinceKunming Key Laboratory of Stem Cell and Regenerative MedicineBasic Medical Laboratory920th Hospital of Joint Logistics Support ForcePLAKunmingYunnan 650032China Department of Immunology of School of Basic Medicine of Guizhou Medical University National and Local Joint Engineering Laboratory of Cell Engineering Biomedical TechnologyKey Laboratory of Regenerative Medicine of Guizhou ProvinceState Key Laboratory of Efficacy and Utilization of Medicinal Plants Co-constructed by Province and MinistryKey Laboratory of Translational Research of Adult Stem Cell of Chinese Academy of Medical SciencesGuiyangGuizhou 550025China

Aging is accompanied by significant inhibition of hematopoietic and immune system function and disruption of bone marrow ***-related alterations in the inflammatory response,immunity,and stem cell niches are at the root of hematopoietic *** the molecular mechanisms underlying hematopoietic and bone marrow aging can aid the clinical treatment of aging-related *** particular,it is unknown how the niche reprograms hematopoietic stem cells(HSCs)in an age-dependent manner to maintain normal hematopoiesis in elderly ***,specific inhibitors and blood exchange methods have been shown to reshape the hematopoietic niche and reverse hematopoietic ***,we present the latest scientific discoveries related to hematopoietic aging and hematopoietic system rejuvenation,discuss the relationships between hematopoietic niche aging and HSC aging,and describe related studies on stem cell-mediated regulation of hematopoietic aging,aiming to provide new ideas for further study.

关键词： Stem cells Hematopoietic stem cell Niche Hematopoietic aging