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A Novel Method for Aging Prediction of Railway Catenary Based on Improved Kalman Filter

Structural Durability & Health monitoring 2024年第1期18卷 73-90页

作者： Jie Li Rongwen Wang Yongtao Hu Jinjun Li School of Electrical Engineering and Automation Henan Institute of TechnologyXinxiang453003China Technology center Sichuan Injet Electric Co.Ltd.Deyang618000China Embedded System Research Institute Xinxiang Engineering Research Center for Intelligent Condition Monitoring of MachineryXinxiang453003China

The aging prediction of railway catenary is of profound significance for ensuring the regular operation of electrified ***,in real-world scenarios,accurate predictions are challenging due to various *** paper addresses this challenge by proposing a novel method for predicting the aging of railway catenary based on an improved Kalman filter(KF).The proposed method focuses on modifying the priori state estimate covariance and measurement error covariance of the KF to enhance accuracy in complex *** comparing the optimal displacement value with the theoretically calculated value based on the thermal expansion effect of metals,it becomes possible to ascertain the aging status of the *** improve prediction accuracy,a railway catenary aging prediction model is constructed by integrating the Takagi-Sugeno(T-S)fuzzy neural network(FNN)and *** this model,an adaptive training method is introduced,allowing the FNN to use fewer fuzzy *** inputs of the model include time,temperature,and historical displacement,while the output is the predicted ***,the KF is enhanced by modifying its prior state estimate covariance and measurement error *** modifications contribute to more accurate ***,a low-power experimental platform based on FPGA is implemented to verify the effectiveness of the proposed *** test results demonstrate that the proposed method outperforms the compared method,showcasing its superior performance.

关键词： Railway catenary Takagi-Sugeno fuzzy neural network Kalman filter aging prediction

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Bovine HSD17B8 gene and its relationship with growth and meat quality traits

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Science Bulletin 2015年第18期60卷 1617-1621页

作者： Yun Ma Ningbo Chen Fen Li Weiwei Fu Yapeng Han Yanlin Chang Xiangxiang Jiang Junya Li Yueyu Bai Xuxin Tan College of Life Sciences Xinyang Normal University Institute of animal Science Chinese Academy of Agricultural Sciences henan Institute of animal Health Supervision henan center of animal products quality monitoring and test

17 β-Hydroxysteroid dehydrogenase type 8 （HSD17B8） is an important regulator of lipid and steroid metabolism. In the present study, we aimed to assess the effects of HSD17B8 on growth and meat quality traits in cattle. Transcription profile analysis showed that HSD17B8 was primarily expressed in the salpinx, liver, and testis. Meanwhile, we identified three SNPs （SNPI： intron 1-A91G; SNP2： exon 1-A90G; and SNP3： intron 8-A86G） of the bovine HSD17B8 gene and investigated its haplotype frequencies and linkage disequilibrium. The detected SNPs were found associated with growth traits （body weight, body length, height at withers, heart girth, hip width, and average daily gain） in native cattle populations （Nanyang and Jiaxian） as well as the meat quality traits （Warner- Bratzler shear force, rib area, dressing percentage, carcass weight, and backfat thickness） in commercial breeds （Angus, Hereford, Limousin, Luxi, Simmental, and Jinnan）. Our results provided evidence that polymorphisms in the HSD17B8 gene were associated with growth traits and meat quality traits. Moreover, our findings might be used for marker-assisted selection in beef cattle breeding program

关键词： HSD17B8. Polymorphisms Growthand meat quality traits Native Chinese cattle

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Copper-Free Click Chemistry-Mediated Assembly of Single Quantum Dot Nanosensor for Accurately monitoring Locus-Specific m^(6)A in Cancer Cells

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Chinese Journal of Chemistry 2024年第5期42卷 499-504页

作者： Yue-Ying Li Ning-Ning Zhao Yi-Xuan Geng Qian Han Jian-Ge Qiu Bing-Hua Jiang Zi-Yue Wang Chun-Yang Zhang Translational Medicine center The First Affiliated Hospital of Zhengzhou UniversityThe Academy of Medical SciencesHenan Institute of Medical and Pharmaceutical Sciences BGI CollegeZhengzhou UniversityZhengzhouHenan450052 China College of Chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinanShandong250014 China School of Chemistry and Chemical Engineering Southeast UniversityNanjingJiangsu211189 China

N6-methyladenosine(m^(6)A)plays an important role in embryogenesis,nuclear export,transcription splicing,and protein translation ***,we demonstrate a copper-free click chemistry-mediated assembly of single quantum dot(QD)nanosensor for accurately monitoring locus-specific m^(6)A in cancer *** m^(6)A-sensitive endoribonuclease MazF can digest the unmethylated A-RNA,and the intact m^(6)A-RNA then hybridizes with DNA probes a and b to produce a sandwich hybrid,initiating the click chemistry to generate probe a–b ligation product via first tandem ligation detection reaction(LDR)***,DNA probes c and d can hybridize with the probe a–b ligation product to generate the probe c–d ligation product via second LDR *** LDR cycles can be repeated through denaturation and annealing reaction to generate abundant biotin-/fluorophore-modified probe c–d ligation products that can easily assemble on the QD surface to induce distinct fluorescence resonance energy transfer(FRET)between QD and *** assay can be homogenously performed without the involvement of copper catalyst,m^(6)A-specific antibody,radioactive labeling,ligase enzyme,enzymatic reverse transcription,and next-generation ***,it can discriminate even 0.01% m^(6)A level in complex samples and accurately measure cellular m^(6)A-RNA expression,providing a promising avenue for clinical diagnostics and biomedical research.

关键词： RNA methylation Click chemistry Förster resonance energy transfer Biosensor Cancer

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Three-dimensional heterogeneous electro-Fenton system with reduced graphene oxide based particle electrode for Acyclovir removal

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Chinese Chemical Letters 2024年第1期35卷 424-430页

作者： Nan Cai Ge Bai Ting Zhang Yongqian Lei Pengran Guo Zhiliang Chen Jingwei Xu Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency test Technology Guangdong Provincial Engineering Research Center for Online Monitoring of Water PollutionInstitute of AnalysisGuangdong Academy of Sciences(China National Analytical CenterGuangzhou)Guangzhou 510070China College of Petrochemical Engineering Lanzhou University of TechnologyLanzhou 730000China Guangdong Engineering Technology Research center of Heavy Metal Pollution Control and Restoration in Farmland Soil South China Institute of Environmental SciencesMEEGuangzhou 510535China

New pollutant pharmaceutical and personal care products(PPCPs),especially antiviral drugs,have received increasing attention not only due to their increase in usage after the outbreak of COVID-19 epidemics but also due to their adverse impacts on water ecological ***-Fenton technology is an effective method to remove PPCPs from *** particle electrodes(MMT/rGO/Fe_(3)O_(4))were synthesized by depositing Fe3O4 nanoparticles on reduced graphene oxide modified montmorillonite and acted as catalysts to promote oxidation performance in a three-dimensional electro-Fenton(3D-EF)*** electrodes combined the catalytic property of Fe3O4,hydrophilicity of montmorillonite and electrical conductivity of graphene oxides,and applied for the degradation of Acyclovir(ACV)with high efficiency and ease of *** optimal condition,the degradation rate of ACV reached 100%within 120 min,and the applicable pH range could be 3 to 11 in the 3D-EF *** stability and reusability of MMT/rGO/Fe_(3)O_(4)particle electrodes were also studied,the removal rate of ACV remained at 92%after 10 cycles,which was just slightly lower than that of the first *** degradation mechanisms were also proposed by methanol quenching tests and FT-ICR-MS.

关键词： Advanced oxidation Three-dimensional electro-Fenton Reduced graphene oxide Acyclovir(ACV) Degradation

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Potential of eNose Technology for monitoring Biological CO2 Conversion Processes

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Transactions of Tianjin University 2024年第5期30卷 381-394页

作者： Muhammad Awais Syed Muhammad Zaigham Abbas Naqvi Sami Ullah Khan M.Ijaz Khan Sherzod Abdullaev Junfeng Wu Wei Zhang Jiandong Hu Department of Electrical Engineering Henan Agricultural University henan International Joint Laboratory of Laser Technology in Agriculture Sciences State Key Laboratory of Wheat and Maize Crop Science Department of Mathematics Namal University Department of Mechanical Engineering Prince Mohammad Bin Fahd University Faculty of Chemical Engineering New Uzbekistan University Scientific and Innovation Department Tashkent State Pedagogical University

Electronic nose（eNose） is a modern bioelectronic sensor for monitoring biological processes that convert CO2into valueadded products, such as products formed during photosynthesis and microbial fermentation. eNose technology uses an array of sensors to detect and quantify gases, including CO2, in the air. This study briefly introduces the concept of eNose technology and potential applications thereof in monitoring CO2conversion processes. It also provides background information on biological CO2conversion processes. Furthermore, the working principles of eNose technology vis-à-vis gas detection are discussed along with its advantages and limitations versus traditional monitoring methods. This study also provides case studies that have used this technology for monitoring biological CO2conversion processes. eNose-predicted measurements were observed to be completely aligned with biological parameters for R2values of 0.864, 0.808, 0.802, and 0.948. We test eNose technology in a variety of biological settings, such as algae farms or bioreactors, to determine its effectiveness in monitoring CO2conversion processes. We also explore the potential benefits of employing this technology vis-à-vis monitoring biological CO2conversion processes, such as increased reaction efficiency and reduced costs versus traditional monitoring methods. Moreover, future directions and challenges of using this technology in CO2capture and conversion have been discussed. Overall, we believe this study would contribute to developing new and innovative methods for monitoring biological CO2conversion processes and mitigating climate change.

关键词： Bioelectronic nose Biological monitoring CO2 conversion Electronic nose (eNose) Gas detection

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Rapid and sensitive detection of Epstein-Barr virus antibodies in nasopharyngeal carcinoma by chemiluminescence strips based on iron-porphyrin single atom nanozyme

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Nano Research 2024年第3期17卷 1827-1836页

作者： Daji Wang Jie Wang Dan Liu Jiuyang He Meiying Wang Haibing Huang Guohui Nie Hui Ding Xiyun Yan Nanozyme Synthesis center Shenzhen Institute of Synthetic BiologyShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China center for Drug Evaluation National Medical Products AdministrationBeijing 100022China Shenzhen Key Laboratory of nanozymes and Translational Cancer Research Department of Otolaryngologyand Shenzhen Institute of Translational MedicineShenzhen Second People’s Hospital/the First Affiliated Hospital of Shenzhen University Health Science CenterShenzhen 518035China CAS Engineering Laboratory for Nanozyme Key Laboratory of Protein and Peptide PharmaceuticalInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China Department of Rheumatology and Immunology Shenzhen Second People’s HospitalThe First Affiliated Hospital of Shenzhen UniversityShenzhen 518055China

The correlation between Epstein-Barr virus(EBV)infection and nasopharyngeal carcinoma(NPC)risk has been extensively *** continual monitoring of EBV-IgAs provides a promising approach of NPC screening in its early *** this study,we successfully synthesized a single-atom nanozyme(SANzyme)through the application of iron-porphyrin based metal organic framework(MOF-FeP).The MOF-FeP possesses precisely-defined electronic and geometric structures that accurately mimic highly-evolved catalytic site of natural *** peroxidase-like activity of MOF-FeP enables it to catalyze the chemiluminescence of luminol *** integrating MOF-FeP into a traditional strip,we created a rapid and highly-sensitive evaluation tool for detecting ***,the MOF-FeP strip enables the simultaneous detection of three EBV-IgAs,greatly improving the accuracy of EBV-associated NPC *** sensitivities of the MOF-FeP strip(75.56%–93.30%)surpass those of current enzyme-linked immunosorbent assay(ELISA)methods(64.44%–82.22%).This test takes only 16 min to perform as opposed to the customary 1–2 h required for standard ***,the MOF-FeP strip is suitable for whole blood samples,thereby significantly simplifying the sample preparation and detection *** conclusion,the MOF-FeP strip combines the simplicity of traditional strip with the high catalytic activity of *** innovative MOF-FeP strip offers a new point-of-care strategy for EBV-IgAs detection,which is expected to markedly facilitate early screening for EBV-associated diseases.

关键词： iron-porphyrin single-atom nanozyme(SANzyme) chemiluminescence strips Epstein-Barr virus(EBV) nasopharyngeal carcinoma(NPC) antibody detection

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Simultaneous identification and quantification of tetrodotoxin in fresh pufferfish and pufferfish-based products using immunoaffinity columns and liquid chromatography/quadrupole-linear ion trap mass spectrometry

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Chinese Journal of Oceanology and Limnology 2017年第4期35卷 883-893页

作者：郭萌萌吴海燕江涛谭志军赵春霞郑关超李兆新翟毓秀 Key Laboratory of testing and Evaluation for Aquatic Product Safety and quality Ministry of AgricultureYellow Sea Fisheries Research InstituteChinese Academy of Fishery Sciences National center for quality Supervision and test of Aquatic products Key Laboratory of Food Safety Risk Assessment Ministry of HealthChina National Center for Food Safety Risk Assessment

In this study, we established a comprehensive method for simultaneous identification and quantification of tetrodotoxin （TTX） in fresh pufferfish tissues and pufferfish-based products using liquid chromatography/quadrupole-linear ion trap mass spectrometry （LC-QqLIT-MS）. TTX was extracted by 1% acetic acid-methanol, and most of the lipids were then removed by freezing lipid precipitation, followed by purification and concentration using immunoaffinity columns （IACs）. Matrix effects were substantially reduced due to the high specificity of the IACs, and thus, background interference was avoided. Quantitation analysis was therefore performed using an external calibration curve with standards prepared in mobile phase. The method was evaluated by fortifying samples at 1, 10, and 100 ng/g, respectively, and the recoveries ranged from 75.8%--107%, with a relative standard deviation of less than 15%. The TTX calibration curves were linear over the range of 1-1 000 ~tg/L, with a detection limit of 0.3 ng/g and a quantification limit of 1 ng/g. Using this method, samples can be further analyzed using an information- dependent acquisition （IDA） experiment, in the positive mode, from a single liquid chromatography-tandem mass spectrometry injection, which can provide an extra level of confirmation by matching the full product ion spectra acquired for a standard sample with those from an enhanced product ion （EPI） library. The scheduled multiple reaction monitoring method enabled TTX to be screened for, and TTX was positively identified using the IDA and EPI spectra. This method was successfully applied to analyze a total of 206 samples of fresh pufferfish tissues and pufferfish-based products. The results from this study show that the proposed method can be used to quantify and identify TTX in a single run with excellent sensitivity and reproducibility, and is suitable for the analysis of complex matrix pufferfish samples.

关键词： tetrodotoxin fresh pufferfish pufferfish-based product immunoaffinity column liquidchromatography/quadrupole-linear ion trap mass spectrometry

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Fast 3D joint inversion of gravity and magnetic data based on cross gradient constraint

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Geodesy and Geodynamics 2023年第4期14卷 331-346页

作者： Sheng Liu Xiangyun Wan Shuanggen Jin Bin Jia Songbai Xuan Quan Lou Binbin Qin Rongfu Peng Dali Sun henan University of Urban Construction Pingdingshan 467041China School of Surveying and Land Information Engineering Henan Polytechnic UniversityJiaozuo 454000China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China The First monitoring and Application center China Earthquake AdministrationTianjin 300180China

The gravity and magnetic data can be adopted to interpret the internal structure of the *** improve the calculation efficiency during the inversion process and the accuracy and reliability of the reconstructed physical property models,the triple strategy is adopted in this paper to develop a fast cross-gradient joint inversion for gravity and magnetic *** cross-gradient constraint contains solving the gradients of the physical property models and performing the cross-product calculation of their *** sparse matrices are first obtained by calculating the gradients of the physical property models derived from the first-order finite ***,the triple method is applied to optimize the storages and the calculations related to the gradients of the physical property ***,the storage compression amount of the calculations related to the gradients of the physical property models and the cross-gradient constraint are reduced to one-fold of the number of grid cells at least,and the compression ratio increases with the increase of the number of grid *** test results from the synthetic data and field data prove that the structural coupling is achieved by using the fast cross-gradient joint inversion method to effectively reduce the multiplicity of solutions and improve the computing efficiency.

关键词： Gravity and magnetic data Joint inversion Triple Cross-gradient constraint

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Recent advances in tertiary amine Lewis base-promoted cycloadditions of allenoates

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Chinese Chemical Letters 2022年第5期33卷 2372-2382页

作者： Manman Song Jing Zhao Er-Qing Li College of Chemistry Green Catalysis CenterZhengzhou UniversityZhengzhou 450001China Xuchang Environmental monitoring center Xuchang 461000China

Lewis base-catalyzed annulations of allenoates have been one of the most powerful synthetic strategies for the synthesis of various valuable cycles,especially in the preparation of biologically active natural products and ***,the effective Lewis bases mainly include tertiary phosphine,NHC and tertiary amine catalysts,among those catalysis,tertiary amine Lewis bases have proven to be effective catalysts for a range of synthetic *** the past decades,tremendous progress in-volving tertiary amines-promoted cycloaddition of allenoates has been made in the chemoselective con-struction of valuable *** review describes a comprehensive and updated summary of tertiary amine Lewis base-promoted annulation reactions of *** reactivities,chemoselectivties and detailed reaction mechanisms will be highlighted in this review.

关键词： Lewis base Tertiary amine Annualtion Allenoates Olefin

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Thermogravimetric-Mass Spectrometric Study of the Pyrolysis Behavior of PVC

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Journal of China University of Mining and Technology 2007年第2期17卷 242-245页

作者： SUN Qing-lei SHI Xin-gang LIN Yun-liang ZHU He WANG Xiao CHENG Chuan-ge LIU Jian-hua Shandong Analysis and test center Shandong Academy of Science Jinan Shandong 250014 China

The pyrolysis characteristics of PVC were systematically investigated using a Netzschne TG thermo-balance coupled to a quadrupole mass spectrometer. The pyrolysis conditions were 0.1 MPa of Ar, a heating rate of 10 ℃/min and a final temperature of 1000℃. Both the thermogravimetric properties and the simultaneous evolution of gaseous products during pyrolysis were studied. The TG/DTG results showed that as the pyrolysis temperature increases the weight loss and weight loss rate of PVC increases. Near 412℃ the weight loss rate attained its peak value. At higher temperatures the rate of loss gradually decreases. The gases evolved during thermogravimetric analysis were analyzed by a mass spectrometer, monitoring the relative intensity of HC1, C6H6, light hydrocarbon and chlorine-containing gases The evolution curves showed that HC1, C6H6, light hydrocarbon and chlorine-containing gases all peak at about 416℃. This is consistent with the fact that the weight loss curves also peak at about 412℃. The extensive HCl evolution is consistent with the high chlorine content of PVC. The formation of these gases can be explained by considering these reactions： dehydrochlorination, intramolecular cyclization and the addition of HCl to unsaturated hydrocarbons.

关键词： pyrolysis PVC gas evolution TG-MS

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