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Predictors of functional independence, quality of life, and return to work in patients with burn injuries in China's Mainland

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Burns & Trauma 2016年第4期4卷 273-283页

作者： Dan Tang Cecilia W.P.Li-Tsang Ricky K.C.Au Xia Shen Kui-cheng Li Xian-feng Yi Lin-rong Liao Hai-yan Cao Ya-nan Feng Chuan-shun Liu Department of rehabilitation Sciences The Hong Kong Polytechnic UniversityHung HomHong Kong Special Administrative RegionChina guangdong provincial work injury rehabilitation hospital GuangzhouChina Department of rehabilitation Sciences The Hong Kong Polytechnic UniversityHung HomHong Kong Special Administrative RegionChina Department of Physiotherapy Guangdong Provincial Work Injury Rehabilitation HospitalGuangzhouChina Department of Occupational Therapy Guangdong Provincial Work Injury Rehabilitation HospitalGuangzhouChina Department of Burn Surgery and Burn rehabilitation Guangdong Provincial Work Injury Rehabilitation HospitalGuangzhouChina

Background:Burn injury may be associated with long-term rehabilitation and disability,while research studies on the functional performance after injuries,quality of life(QOL),and abilities to return to work of burn patients are *** outcomes are related not just to the degree and nature of injuries,but also to the socio-economical background of the *** study aimed to identify the factors which might affect burn patients’abilities to reintegrate back to the society based on a sample in China's ***:A retrospective study was conducted to collect data of demographic characteristics,medical data about burn injuries,physical and psychological status,and self-perceived QOL at the initial phase and upon discharge from a rehabilitation hospital,timing of rehabilitation,and duration of rehabilitation *** hundred fifteen patients with burn injuries were recruited in the *** linear regression and logistic regression were used to obtain a model to predict the functional abilities and the perceived QOL at discharge and their changes during rehabilitation,as well as the post-injury work status within 6 months after ***:The functional performance at discharge and its change were significantly predicted by the functional abilities and QOL at the admission,duration of treatment,timing of rehabilitation,payer source,and total body surface area *** perceived QOL at discharge and its change were significantly predicted by the baseline QOL at admission and duration of *** significant predictors of work status within 6 months post-discharge included age,education,payer source,total body surface area burned,perceived QOL,and bodily pain at ***:The present study identified a number of factors affecting the rehabilitation outcomes of people with burn *** of these predictors may help clinicians assess the rehabilitation potential of burn survivors and assist in resource

关键词： Burns Functional independence Quality of life Return to work Predictors rehabilitation

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Autonomic Dysreflexia Severity between Urodynamics and Cystoscopy in Patients with Spinal Cord injury above T6

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International Journal of Clinical Medicine 2021年第8期12卷 351-356页

作者： Heyi Zhen Tianhai Huang Xiaoyi Yang Qiuling Liu Qingqing Li Maping Huang Hui Chen Department of Traumatic Brain injury rehabilitation Guangdong Province Work Injury Rehabilitation Hospital Guangzhou China Department of Urology Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China

Objective: The objective is to evaluate autonomic dysreflexia (AD) severity between urodynamics and cystoscopy in patients with spinal cord injury (SCI) above thoracic 6 (T6). Design: It is a cross-sectional survey. Subject and methods: The study was carried out in 22 patients with SCI above T6 who underwent both procedures of urodynamics and cystoscopy;all patients developed episodes of AD. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured and recorded at the beginning and during the various stages of the two examinations. AD was defined as a rise in SBP above 20 mm Hg. Results: There was no significant difference in SBP and DBP at baseline before urodynamics and cystoscopy. Both urodynamics and cystoscopy triggered episodes of AD. The volume of water instilled during cystoscopy was typically standard and smaller (150 mL) in comparison with urodynamics, where volume varied depending on cystometric bladder capacity (the mean bladder volume in our study was 234.86 ± 139.06 mL). The SBP was significantly different between cystoscopy and urodynamics (49.23 ± 23.07 mm Hg and 35.14 ± 15.75 mm Hg, respectively;P = 0.023). Conclusions: Although bladder distension during cystoscopy was less than that in urodynamics, the severity of AD was more pronounced during cystoscopy. It is recommended that monitoring of cardiovascular parameters during these procedures should be routinely performed.

关键词： Autonomic Dysreflexi Spinal Cord injury Urodynamics Cystoscopy

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Initial Experience with Mirabegron for the Treatment of Neurogenic Lower Urinary Tract Dysfunction

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Open Journal of Urology 2021年第8期11卷 305-311页

Background: Though anticholinergic drugs are considered the standard treatment for neurogenic detrusor overactivity, it is far from an ideal tool, because of their adverse effects such as Constipation or not respond sufficiently for a substantial proportion of patients. Recently mirabegron has become a commonly used overactive bladder medication in the general population, but few studies about mirabegron for the treatment of neurogenic detrusor overactivity. Objective: To evaluate the efficacy and safety of mirabegron for the treatment of neurogenic lower urinary tract dysfunction. Study Design: Prospective study. Methods: This prospective study included 13 adult patients with neurogenic lower urinary tract dysfunction as a result of spinal cord injury. All patients receiving mirabegron treatment (50 mg once daily) at least 6 weeks. The effective outcomes included the mean urine volume per catheterization, urinary incontinence episodes and Incontinence Specific Quality of Life Instrument. We monitored the blood pressure and heart rate to assess the cardiovascular safety, other adverse events were also recorded. Results: A total of 13 patients were included. After 6 weeks of treatment, all patients experienced a significant increase in the mean volume of per catheterization from 238.46 ± 65.43 ml to 327.69 ± 59.04 ml (p = 0.001). There is a significant reduction in the volume of urine leakage (463.85 ± 247.98 ml VS 180.00 ± 190.96 ml, p = 0.003) and incontinence episodes per 24 h (4.46 ± 2.03 VS 1.92 ± 1.50, p = 0.001). Significant improvement in mean Incontinence Specific Quality of Life Instrument was also found (p = 0.001). No patients reported dry mouth during the study, and the cardiovascular safety were acceptable. Conclusion: Mirabegron is safe and effective in the treatment of neurogenic lower urinary tract dysfunction. It might be a good choice for reducing

关键词： Neurogenic Lower Urinary Tract Mirabegron Detrusor Overactivity Spinal Cord injury

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Combined Detrusor and External Urethral Sphincter BTX-A Injections for Detrusor Overactivity and Detrusor External Sphincter Dyssynergia Secondary to Spinal Cord injury

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Open Journal of Urology 2021年第2期11卷 45-51页

作者： Maping Huang Heyi Zhen Tianhai Huang Xiaoyi Yang Qiuling Liu Qingqing Li Hui Chen Department of Urology Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China Department of Traumatic Brain injury rehabilitation Guangdong Province Work Injury Rehabilitation Hospital Guangzhou China

Objective: To evaluate the efficacy and safety of Combined detrusor and external urethral sphincter BTX-A injections for detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) secondary to spinal cord injury. Study Design: Prospective study. Methods: The study was carried out in 18 SCI patients with detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) receiving Combined detrusor and external urethral sphincter BTX-A injections treatment. Contain 200 U botulinum toxin intradetrusor and 100 U external urethral sphincter injections. The effective outcomes included maximum detrusor pressure at first DO and DESD (PdetmaxDO-DESD), volume at first DO and DESD (VDO-DESD), maximum urethral closure pressure (MUCP), and Incontinence-Specific Quality-of-Life Instrument (I-QoL). Adverse events were recorded. Results: All patients experienced a significant mean reduction in PdetmaxDO-DESD (50.75%), maximum urethral closure pressure (26.34%) and a significant mean increase in VDO-DESD (63.00%) 12-weeks post-injection. Significant (p Conclusion: Combined detrusor and external urethral sphincter BTX-A injections is a good choice for patients with DO and DESD secondary to spinal cord injury. It could not only protect the upper urinary tract but also improve quality of life.

关键词： Detrusor Overactivity Detrusor External Sphincter Dyssynergia BTX-A Spinal Cord injury

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Clinical Study on Evaluation of Autonomic Nervous Dysfunction Based on Imaging Urodynamic Examination with Slow Filling and Synchronous Blood Pressure Monitoring in the Patients with Cervicothoracic Spinal Cord injury

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Open Journal of Urology 2021年第4期11卷 112-123页

作者： Qingqing Li Hui Chen Xihui Xiao Weibin Zeng Shuqing Wu Maping Huang Xinghua Yang Department of Neurological rehabilitation Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China

Objective: Explore the rule of autonomic nervous dysfunction in the patients with urination disorder after high level spinal cord injury, and seek a safe, objective and accurate method to evaluate autonomic nervous function. Patients and Method: 48 patients with dysuria after cervicothoracic SCI were selected. Before, during and after imaging urodynamic examination with slow filling in supine position, blood pressure and ECG were monitored simultaneously. The symptoms of sweating, shivering, headache, flushing and chills were observed and recorded. The study of the relationship among the changes of blood pressure, heart rate and urodynamic indexes and the above symptoms was analyzed. Results: They were divided into three groups: group A (no obvious abnormality), group B (hyperactivity) and group C (hypoactivity) according to their BP, HR and existing the symptoms or not. Conclusion: The incidence of autonomic dysfunction in the high level SCI patients with dysuria was very high (79.17%), most of them were hyperactivity, and a few were low function. The changes of SBP and DBP in the hypoactivity group all appeared an increasing and then declining trend, while the change of HR in the low function one was lower than normal and decreased continuously. The main inducements of AD are neurogenic detrusor overactivity, detrusor sphincter dyssynergia, elevated abdominal pressure and abnormal bladder sensitivity. The asymptomatic patients had a higher occurrence rate (43.75%). Only by imaging urodynamic examination with slow filling and synchronous blood pressure monitoring, can autonomic nervous function of the patients be evaluated safely, objectively, early and accurately.

关键词： High Level Spinal Cord injury Autonomic Nervous Function Imaging Urodynamic Examination Slow Filling Synchronous Blood Pressure Monitoring

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Effects of multiple nursing cares on quality of life in individuals with coronary artery disease complicated with diabetes mellitus

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South China Journal of Cardiology 2015年第3期16卷 175-181页

作者：杨轶林丽霞陈冬燕刘智张意辉 guangdong General hospital Guangdong Academy of Medical Sciences Department of Orthopedic rehabilitation Guangdong Provincial Work Injury Rehabilitation Hospital

Patients with coronary artery disease （CAD） complicated with diabetes mellitus （DM） have a reduced quality of life （QOL） partly due to their limited range of physical activity and independence. The primary objective of this study was to examine the effect of the application of the multiple nursing cares on QOL and de- pressive symptoms in individuals with CAD complicated with DM. Methods A total of 82 CAD complicated with DM patients in guangdong General hospital from January 2014 to January 2015 were selected, and random- ly divided into control group （n = 41） and experimental group （n = 41） according to World Health Organization DM diagnosis criteria. The subjects in control group received routine nursing care, and the subjects in experimen- tal group were treated with the multiple nursing cares additionally for a 10-week period. The outcome measures include the Short Form-36 Health Survey （SF-36）, and Self-Rating Anxiety Scale （SAS）. Results Following 10-week intervention, the QOL scores and SAS anxiety scores in all groups were improved （P 〈 0.05）. In addi- tion, QOL and SAS anxiety scores in the experimental group were significantly improved （P 〈 0.05）, when com- pare with the control group. Conclusions Based on the results of this study, the application of the multiple nurs- ing cares to individuals with CAD complicated with DM is effective in increasing selected aspects of a general QOL and improving the anxiety situation in individuals with CAD complicated with DM. It is worthwhile to be widely used in clinical practice.

关键词： Multiple nursing care coronary artery disease diabetes meUitus quality of life depression

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A clinical study on the effects of ICU cardiac rehabilitation nursing care on patients with totally thoracoscopic cardiac operation

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South China Journal of Cardiology 2015年第4期16卷 244-251页

作者：梁炽琼刘智陈冬燕张意辉 guangdong General hospital Guangdong Academy of Medical Sciences Department of Orthopedic rehabilitation Guangdong Provincial Work Injury Rehabilitation Hospital

Background The video-assisted thoracoscopic surgical techniques are widely used in the treatment of patients with congenital heart diseases with good outcomes. However, the feasibility and significance of nurse based early cardiac rehabilitation in cardiac intensive care unit （ICU） for patients with totally thoracoscopic cardi- ac operation has been seldom studied. Methods Thirty-six patients with totally thoracoscopic cardiac operation under the condition of the cardiac ICU in guangdong General hospital were random allocated to the intervention group and the control group between January 2012 to December 2014. The control group received standard nursing care, and the intervention group received early cardiac rehabilitation nursingcare in addition to standard care. The outcome measures included the oxygen saturation （SPO2%）, vital capacity, forced expiratory volume in 1 second （FEV1）, and pain in the thoracic wound （visual analogue scale, VAS）, which were measured at the baseline and within 2-day after 4-week nursingcare. For safety reason, we also monitored the rate of perceived exertion （RPE）, heart rate, systemic blood pressure. Results There were non-significant differences between the groups in age, sex, total number of comorbid conditions, total number of medications, surgical time, and anesthetic time （P〉0.05）. Following 4 weeks treatment, the cardiopulmonary functions and VAS scorewere improved （P〈0.05） in all groups. In addition, the improvements were more in the early cardiac rehabilitation nurse care group than in the control group （P〈0.05）. Conclusion The early cardiac rehabilitation nursing care in cardiac ICU is safe, feasible and beneficial for patients with totally thoracoscopic cardiac operation.

关键词： totally thoracoscopic cardiac operation nursing care early stage coronary artery disease cardiacrehabilitation

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Catgut Implantation at Baliao and Xingfu One Acupuncture Point to Treat Dysdefecation in Patients with Incomplete Spinal Cord injury: Three Cases Report

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Open Journal of Urology 2020年第6期10卷 211-216页

作者： Qingqing Li Laiming Yu Hui Chen Ruzhi Zhang Xinghua Yang Qiuling Liu Maping Huang Dahui Zhang Shuqing Wu Department of Neurourological rehabilitation Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China Guangzhou Southern Mingdao Modified Acupuncture and Moxibustion Catgut Embedding Promotion Center Guangzhou China Subhealth Center Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China Department of Spine and Spinal Cord injury rehabilitation Guangdong Provincial Work Injury Rehabilitation Hospital Guangzhou China

Objective: To probe into the effect of catgut implantation at Baliao and Xingfu One Acupuncture Point on dysdefecation in patients with incomplete spinal cord injury (SCI). Methods: Three SCI patients voluntarily accepted catgut embedding at Baliao and Xingfu One Acupuncture point. Before and after treatment, they were filled out the self-rating scale of defecation, including the data of defecation frequency, total defecation time, defecation effort, fecal texture, fecal characteristics and fecal incontinence, etc. Results: Compared with the baseline data, constipation was improved and fecal incontinence was disappeared. Conclusions: Catgut implantation at Baliao and Xingfu One Acupuncture Point is effectual for patients with neurogenic dysporia secondary to incomplete SCI.

关键词： Baliao Xingfu One Acupuncture Point Catgut Implantation Spinal Cord injury Dysdefecation

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Cardiovascular responses induced by whole-body vibration training in patients with subacute stroke

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South China Journal of Cardiology 2019年第1期20卷 15-24页

作者： LIAO Lin-rong LIAO Man-xia WANG Jun WANG Chu-shan ZHANG Zhi-wei LIU Kai-feng MA Jian-qing Department of Physical Therapy Guangdong Provincial Work Injury Rehabilitation Hospital Department of rehabilitation Yixing JORU Rehabilitation Hospital

Background Whole-body vibration(WBV) therapy has become a common treatment in rehabilitation of various patient populations. While it has been shown in healthy young adults that the oxygen consumption rate(VO_2)and heat rate(HR) are significantly increased when WBV is added to exercise. However, the cardiovascular response to WBV in patients with subacute stroke is unknown. The objective of this study was to determine the acute cardiovascular responses to WBV during the various exercises in different WBV conditions in patients with subacute stroke(onset less than 3 months). Methods A total of 54 subjects with subacute stroke performed six exercises while being exposed to 3 WBV conditions:(1) no WBV,(2) low WBV intensity [amplitude: 0.6 mm,frequency: 20 Hz, peak acceleration: 0.96 gravitational constant(G)], and(3) high WBV intensity(amplitude:0.44 mm, frequency: 30 Hz, peak acceleration: 1.61 G). The cardiovascular responses(HR and VO_2) were measured by a FitMateTMPro metabolic system during the 6 exercises. Two-way repeated measures ANOVA was used to compare the VO_2, and HR data across the different conditions. In addition, we calculated the rate pressure product(RPP) =(HR × systolic blood pressure)/100, for measuring the myocardial oxygen demand. Two-way ANOVA with repeated measures was used to compare the RPP data across the different test conditions. Results Exposure to WBV(high-and low-intensity protocols) significantly induced higher VO_2 by 0.35-1.07 mL·kg-1·min-1(P0.05). For RPP, there was an overall significant effect between pre-and post-WBV(P<0.001). The main effect of WBV intensity(P=0.572), and intensity × time interaction effect(P=0.756), however,were not significant. Conclusions HR and VO_2 are increased significantly with ad

关键词： whole body vibration cerebrovascular accident cardiovascular response oxygen consumption heart rate rate pressure product

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Free PSA performs better than total PSA in predicting prostate volume in Chinese men with PSA levels of 2.5–9.9 ng ml−1

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Asian Journal of Andrology 2023年第1期25卷 82-85页

作者： Ma-Ping Huang Ping Tang Cliff S Klein Xing-Hua Wei Wei Du Jin-Gao Fu Tian-Hai Huang Hui Chen Ke-Ji Xie Department of Urology The First Affiliated Hospital of Jinan UniversityGuangzhou 510630China Department of Urology Guangzhou First People's HospitalSouth China University of TechnologyGuangzhou 510180China Department of Urology Guangdong Provincial Work Injury Rehabilitation HospitalGuangzhou 510440China Department of Urology Guangdong Provincial Hospital of Integrated Traditional Chinese and Western MedicineFoshan 528253China Department of Urology Jiangmen Central HospitalAffiliated Jiangmen Hospital of Sun Yat-Sen UniversityJiangmen 529099China

This study investigated whether free prostate-specific antigen(fPSA)performs better than total PSA(tPSA)in predicting prostate volume(PV)in Chinese men with different PSA levels.A total of 5463 men with PSA levels of<10 ng ml^(−1) and without prostate cancer diagnosis were included in this *** were classified into four groups:PSA<2.5 ng ml^(−1),2.5–3.9 ng ml^(−1),4.0–9.9 ng ml^(−1),and 2.5–9.9 ng ml^(−1).Pearson/Spearman's correlation coefficient(r)and receiver operating characteristic(ROC)curves were used to evaluate the ability of tPSA and fPSA to predict *** correlation coefficient between tPSA and PV in the PSA<2.5 ng ml^(−1) cohort(r=0.422;P<0.001)was markedly higher than those of the cohorts with PSA levels of 2.5–3.9 ng ml^(−1),4.0–9.9 ng ml^(−1),and 2.5–9.9 ng ml^(−1)(r=0.114,0.167,and 0.264,respectively;all P≤0.001),while fPSA levels did not differ significantly among different PSA *** under ROC curve(AUC)analyses revealed that the performance of fPSA in predicting PV≥40 ml(AUC:0.694,0.714,and 0.727)was better than that of tPSA(AUC=0.545,0.561,and 0.611)in men with PSA levels of 2.5–3.9 ng ml^(−1),4.0–9.9 ng ml^(−1),and 2.5–9.9 ng ml^(−1),respectively,but not at PSA levels of<2.5 ng ml^(−1)(AUC:0.713 vs 0.720).These findings suggest that the relationship between tPSA and PV may vary with PSA level and that fPSA is more powerful at predicting PV only in the"gray zone"(PSA levels of 2.5–9.9 ng ml^(−1)),but its performance was similar to that of tPSA at PSA levels of<2.5 ng ml^(−1).

关键词： prostate cancer prostate-specific antigen prostatic hyperplasia volume

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