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Chinese herbal medicine decreases incidence of hepatocellular carcinoma in diabetes mellitus patients with regular insulin management

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 716-731页

作者： Hsiang-Chun Lai Ju-Chien Cheng Hei-Tung Yip Long-Bin Jeng Sheng-Teng huang graduate institute of Chinese Medicine School of Chinese MedicineCollege of Chinese MedicineChina Medical UniversityTaichung 404328TaiwanChina Department of Medical Laboratory Science and Biotechnology China Medical UniversityTaichung 404TaiwanChina management Office for Health Data China Medical University HospitalTaichung 404327TaiwanChina Organ Transplantation Center China Medical University HospitalTaichung 40447TaiwanChina Department of Chinese Medicine China Medical University HospitalSchool of Chinese MedicineChina Medical UniversityTaichung 40447TaiwanChina

BACKGROUND Type 2 diabetes mellitus(DM)is an independent risk factor for hepatocellular carcinoma(HCC),while insulin is a potent *** a new therapeutic modality for preventing insulin users from developing HCC is a critical goal for *** To investigate whether regular herbal medicine use can decrease HCC risk in DM patients with regular insulin *** We used data acquired from the Taiwan,Chinaese National Health Insurance research database between 2000 and *** identified patients with DM who were prescribed insulin for>3 *** herb user group was further defined as patients prescribed herbal medication for DM for>3 months per annum during RESULTS We initially enrolled 657144 DM patients with regular insulin use from 2000 to *** these,46849 patients had used a herbal treatment for DM,and 140547 patients were included as the matched control *** baseline variables were similar between the herb users and *** patients with regular herb use had a 12%decreased risk of HCC compared with the control group[adjusted hazard ratio(aHR)=0.88,95%CI=0.80–0.97].The cumulative incidence of HCC in the herb users was significantly lower than that of the *** with a herb use of>5 years cumulatively exhibited a protective effect against development of HCC(aHR=0.82,Phuang Qi)plus Salvia miltiorrhiza Bunge(Dan Shen),and Astragalus propinquus(huang Qi)plus Trichosanthes kirilowii Maxim.(Tian hua Fen)were the most frequent combination of single ***,Ji Sheng Shen Qi Wan plus Dan Shen was the most frequent combination of herbs and *** This large-scale retrospective cohort study reveals th

关键词： Hepatocellular carcinoma Diabetes mellitus Insulin Herb Taiwan,Chinaese National health insurance research database

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Modifying IPA with DEMATEL Composite Importance

Modifying IPA with DEMATEL Composite Importance

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2011 International Conference on Fuzzy Systems and Neural Computing(FSNC 2011)

作者： Yu-Chen Lee Yi-Fang Hsieh graduate institute of technology management chung hua university

Importance Performance Analysis（IPA）can help managers identify improvement *** causation and diversity of importance of service attributes,traditional IPA cannot accurately analyze the importance of service attributes and priority ranking for improvement,leading to wrongful decision *** establish adequate decision-making methods by locating core issues,we first employ Decision Making Trial and Evaluation Laboratory（DEMATEL）to assay causation among service attributes and estimate implicit importance via multiple regression analyses as the weights of service attributes,and then included the weights in composite importance,and used the weighted DEMATEL composite importance to estimate IPA importance for regulating the importance of service ***,the case study on mobile telecommunications companies in Taiwan evidences the effectiveness that modifying IPA with DEMATEL composite importance can help managers make decisions.

关键词： Importance Performance Analysis(IPA) Decision Making Trial and Evaluation Laboratory(DEMATEL) Composite Importance

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Relationship Between Measured Friction Coefficients and Two Tread Groove Design Parameters for Footwear Pads

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Tsinghua Science and technology 2006年第6期11卷 712-719页

作者： LI Kai Way CHEN Chin Jung LIN Ching-hua HSU Yao Wen Liberty Mutual Research institute for Safety 71 Frankland RoadHopkinton MA 01748 USA Department of Industrial ManagementChung-Hua University770 Wu Fu RoadSec 2Hsin ChuTaiwan 300China Department of Industrial management Chung-Hua University770 Wu Fu RoadSec 2 Hsin ChuTaiwan 300 China Industrial Engineering and management Department TA-Hwa Institute of Technology1 Dahua RoadQionglin ShiangHsinchu CountyTaiwan 307China

The shoe sole geometrical design parameters are believed to be important factors affecting the coefficient of friction （COF） between the shoe/floor interface. This study is concerned with the relationship between the measured COF and the tread groove orientation and width on the footwear pad. Friction measurements using the Brungraber Mark Ⅱ slipmeter were conducted. Six tread groove width/orientations designs on the footwear pads under 27 footwear material/floor/contamination conditions were tested. The results show that tread orientation and width affect the measured COF significantly. Wider grooved footwear pads result in higher COF values and footwear pads with tread grooves perpendicular to the friction measurement direction have higher COF values. A regression model using measured COF as the dependent variable and tread groove width, groove orientation, footwear material, floor, and contamination conditions as independent variables was established. The models are significant at p〈0.0001 with R^2 of 0.97, which may be used in predicting the COF at the shoe-floor interface .

关键词： slipping and falling incidents friction measurement tread groove design Brungraber Mark Ⅱ slipmeter

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MOBILE INFORMATION SYSTEMS

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中国通信：英文版 2015年第12期12卷 I0002-I0003页

作者： WANG Shangguang Ching-Hsien Hsu David Taniar Patrick Hung Beijing university of Posts and Telecommunications department of computer science and information engineering at chung hua university Taiwan China the Faculty of Information technology Monash UniversityAustralia university of Ontario institute of technology Canada the IEEE Transactions on Services Computing International Journal of Web Services Research and International Journal of Business Process and Integration Management the Information Systems Frontiers by Springer

With the popularity of mobile infrastructures providing higher bandwidth and constant connection to the network from virtually anytime and everywhere,the way people use information resources is radically *** can use mobile devices such as mobile phones,pocket PCs,laptops,etc.,to obtain services/applications which are based on the mobile

关键词：移动信息系统管理信息系统信息资源笔记本电脑基础设施移动设备掌上电脑应用程序

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Blockchain technology Based Information Classification management Service

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Computers, Materials & Continua 2021年第5期67卷 1489-1501页

作者： Gi-Wan Hong Jeong-Wook Kim Hangbae Chang Department of Security Convergence Graduate SchoolChung-Ang UniversitySeoul06974Korea Department of Industrial Security Chung-Ang UniversitySeoul06974Korea

Hyper-connectivity in Industry 4.0 has resulted in not only a rapid increase in the amount of information,but also the expansion of areas and assets to be *** terms of information security,it has led to an enormous economic cost due to the various and numerous security solutions used in protecting the increased ***,it has caused difficulties in managing those issues due to reasons such as mutual interference,countless security events and logs’data,*** this security environment,an organization should identify and classify assets based on the value of data and their security perspective,and then apply appropriate protection measures according to the assets’security classification for effective security *** there are still difficulties stemming from the need to manage numerous security solutions in order to protect the classified *** this paper,we propose an information classification management service based on blockchain,which presents and uses a model of the value of data and the security *** records transactions of classifying assets and managing assets by each class in a distributed ledger of *** proposed service reduces assets to be protected and security solutions to be applied,and provides security measures at the platform level rather than individual security solutions,by using *** the rapidly changing security environment of Industry 4.0,this proposed service enables economic security,provides a new integrated security platform,and demonstrates service value.

关键词： Information classification data integrity document security blockchain CIA

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Thermodynamic Calculation and MnS Solubility of Mn-Ti Oxide Formation in Si-Mn-Ti Deoxidized Steel

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Journal of Iron and Steel Research International 2010年第2期17卷 10-16页

作者： ZHUO Xiao-jun WANG Yuan-qi WANG Xin-hua Lee Hae-geon technology management Section China Minmetals Corporation Beijing 100044 China Department of Scienee and technology Information China Iron and Steel Research Institute Group Beijing 100081 China Metallurgieal and Ecological Engineering Sehool University of Science and Technology Beijing Beijing100083 China graduate institute of Ferrous Teehnology Pohang University of Science and TechnologyPohang 790-784 South Korea

Mn-Ti oxides in Si-Mn-Ti deoxidized steels after cooling in the furnace were investigated. The composition and morphology of inclusions were analyzed by using FE-SEM with EDS. Mn-Ti oxides were found to be effective sites to induce intragranular ferrite formation. The thermodynamic calculation was employed to interpret the critical condition for Mn-Ti oxide formation. Mn-Ti oxide formation was controlled not only by Mn and Ti content, but also by total oxygen content in steel. When the Mn and Ti contents were around 1.5% and 0. 005% --0.01%, respectively, Mn-Ti oxide could form as the total oxygen content was 0. 001%- 0. 002 %. The experimental results were in good agreement with thermodynamic calculation results. Also, MnS solubilit：（ was examined in Mn-Ti oxide inclusion system. With an increase of MnO content in Mn-Ti oxide, MnS solubility in the oxides increased. MnS precipitation benefited from high MnO content in Mn-Ti oxide.

关键词： Si-Mn-Ti deoxided steel Mn-Ti oxide MnS intragranular ferrite thermodynamic calculation

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Hair growth-promotion effects and antioxidant activity of the banana flower extract HappyAngel^(■):double-blind, placebo-controlled trial

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Food Science and Human Wellness 2023年第5期12卷 1917-1923页

作者： Chia-hua Liang Yung-Hsiang Lin Yung-Kai Lin Chi-Fu Chiang Department of Cosmetic Science and institute of Cosmetic Science Chia Nan University of Pharmacy and ScienceTainan 71710China Research&Design Center TCI CO.Ltd.Taipei 114722China institute of Food Safety and Risk management Department of Food ScienceTaiwan Ocean UniversityKeelung 202301China graduate institute of Biomedical Engineering Chung Hsing UniversityTaichung 202301China

Banana flowers contain various bioactive components, including several antioxidants with anti-inflammatory effects. However, it is unclear whether they can reduce and prevent hair loss. This study examines the effect of banana flower extracts on preventing hair loss and strengthening hair roots. The banana flower extract(HappyAngel^(■))was used to treat human hair follicle dermal papilla cells(HFDPCs)and the expression of reactive oxygen species(ROS), dihydrotestosterone(DHT), and hair-related genes(SRD5A1, SRD5A2, AR, and KROX20)were monitored. Fifty subjects were divided into a placebo group and a banana flower group. The experimental group consumed banana flower extract daily for twelve weeks and then underwent hair testing, hair-related genes analysis, collection of hair loss, and questionnaires. The results showed that the banana flower extract significantly increased hair cell growth and decreased the expression of ROS, DHT, and hair follicle growth inhibition-related SRD5A1, SRD5A2, and AR genes, and significantly increased the expression of hair growth-related KROX20 gene in HFDPCs. Consuming banana flower extract for twelve weeks increased the hair root diameter and reduced hair loss and scalp redness compared to the placebo group. Thus, banana flower extract(HappyAngel^(■))can stimulate hair growth and inhibit the activation of hair loss genes.

关键词： Banana flower Dihydrotestosterone Hair loss ROS Follicle dermal papilla cells

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Ergonomics in the Perception of Hand Exertion for Females

Ergonomics in the Perception of Hand Exertion for Females

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工程和商业管理国际学术会议

作者： Kai Way LI Dept.Industrial management Chung-Hua University

Borg’s CR-10 scales are commonly used to quantify perceived muscular exertion for body *** female subjects were recruited in the study the power grip force at four perceived exertion levels using either dominant or non-dominant hand under two posture *** was found that the subjects tended to apply a higher power grip force （%MVC） than they *** grip forces between the two hands were significantly different when the exertion level was nearly *** regression models were established for the subjects to describe the relationship between the perceived hand exertion and measured grip force,and used,and hand/arm *** the models were statistically significant （p＜0.0001） with R 2 values 0.97 or higher.

关键词： Hand exertion power grip female subject perception

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Design of an Information Security Service for Medical Artificial Intelligence

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Computers, Materials & Continua 2022年第1期70卷 679-694页

作者： Yanghoon Kim Jawon Kim Hangbae Chang Department of Cyber Drone Bot Military Engineering Shinhan UniversityUijeongbu-si11644Gyeonggi-doKorea Department of Security Convergence Graduate SchoolChung-Ang UniversityDongjack-gu06974SeoulKorea Department of Industrial Security Chung-Ang UniversityDongjak-gu06974SeoulKorea

The medical convergence industry has gradually adopted ICT devices,which has led to legacy security problems related to ICT ***,it has been difficult to solve these problems due to data resource *** problems can cause a lack of reliability in medical artificial intelligence services that utilize medical ***,to provide reliable services focused on security internalization,it is necessary to establish a medical convergence environment-oriented security management *** study proposes the use of system identification and countermeasures to secure systemreliabilitywhen using medical convergence environment information in medical artificial *** checked the life cycle of medical information and the flow and location of information,analyzed the security threats that may arise during the life cycle,and proposed technical countermeasures to overcome such *** verified the proposed countermeasures through a survey of *** requirements were defined based on the information life cycle in the medical convergence *** also designed technical countermeasures for use in the security management systems of hospitals of diverse sizes.

关键词： Medical artificial intelligence medical information security convergence environment

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Altered heart rate variability and pulse-wave velocity after spinal cord injury

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World Journal of Clinical Cases 2022年第27期10卷 9680-9692页

作者： Hsi-Kai Tsou Kuan-chung Shih Yueh-Chiang Lin Yi-Ming Li Hsiao-Yu Chen Functional Neurosurgery Division Neurological InstituteTaichung Veterans General HospitalTaichung 404Taiwan Department of Rehabilitation Jen-Teh Junior College of MedicineNursing and ManagementMiaoli County 356Taiwan College of Health National Taichung University of Science and TechnologyTaichung 403Taiwan College of Medicine National Chung Hsing UniversityTaichung 402Taiwan Research Assistant The Rong Sing Medical FoundationTaichung 404Taiwan Research Assistant Neurological InstituteTaichung Veterans General HospitalTaichung 404Taiwan Research Assistant Department of NursingNational Taichung University of Science and TechnologyTaichung 403Taiwan graduate institute of Applied Science and technology National Taiwan University of Science and TechnologyTaipei 106Taiwan Department of Nursing National Taichung University of Science and TechnologyTaichung 403Taiwan

BACKGROUND Heart rate variability(HRV) and pulse-wave velocity(PWV),indicators of cardiac function,are altered in patients with spinal cord injury(SCI),suggesting that autonomic cardiac function and arterial stiffness may underlie the high risk of cardiovascular complications in these *** study has simultaneously investigated HRV and PWV in the same *** To evaluate cardiovascular complications in SCI patients by comparing HRV and PWV between patients with and without *** In this cross-sectional pilot study,patients with(n = 60) and without SCI(n = 60) were recruited from December 7,2019 to January 21,*** participant received a five-minute assessment of HRV and the cardiovascular system using the Medicore HRV Analyzer SA-3000 *** in HRV and PWV parameters between participants with and without SCI were statistically *** We observed a significant difference between participants with and without SCI with respect to the standard deviation of all normal-to-normal intervals,square root of the mean sum of squared successive risk ratio interval differences,physical stress index,total power,very-low frequency,low frequency,high frequency,and arterial *** Patients with SCI have weaker sympathetic and parasympathetic activity as well as lower arterial elasticity compared to those without,suggesting that SCI may increase cardiac function loading.

关键词： Acceleration plethysmography Cardiac function Heart rate variability Pulse wave velocity Spinal cord injury

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