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China CDC Weekly--A Step Forward for China’s public health System and for global health Security

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China CDC weekly 2019年第2期1卷 19-20页

作者： Ron Moolenaar RJ Simonds Division of global health Protection Center for Global HealthU.S.CDC Center for global health U.S.CDC Country Director US CDC China

Congratulations to China CDC on the launch of the China CDC *** timely,accurate reporting on public health surveillance,epidemiologic investigations,and emergency responses,and by sharing lessons learned and evidence-... 详细信息

关键词： CDC Forward public

In vitro evaluation of inorganic and methyl mercury mediated cytotoxic effect on neural cells derived from different animal species

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Journal of Environmental Sciences 2016年第3期28卷 138-145页

作者： Jing Tong Youwei Wang Yuanan Lu institute of TCM & Natural Products School of Pharmaceutical SciencesWuhan University Department of public health Sciences University of Hawaii at Manoa global health Center School of Public HealthWuhan University

To extend the current understanding of the mercury-mediated cytotoxic effect,five neural cell lines established from different animal species were comparatively analyzed using three different endpoint bioassays：thiazolyl blue tetrazolium bromide,3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyl tetrazolium bromide assay（MTT）,neutral red uptake assay（NRU）,and Coomassie blue assay（CB）.Following a 24-hr exposure to selected concentrations of mercury chloride（HgCl_2） and methylmercury（Ⅱ） chloride（MeHgCl）,the cytotoxic effect on test cells was characterized by comparing their 50%inhibition concentration（IC_（50）） *** results indicated that both these forms of mercury were toxic to all the neural cells,but at very different *** IC_（50）values of MeHgCl among these cell lines ranged from 1.15±0.22 to 10.31 ± 0.70 μmol/L while the IC_（50） values for HgCl_2 were much higher,ranging from 6.44 ± 0.36 to 160.97±19.63 μmol/L,indicating the more toxic nature of *** IC_（50） ratio between HgCl_2and MeHgCl ranged from 1.75 to 96.0,which confirms that organic mercury is much more toxic to these neural cells than inorganic *** these cell lines,HGST-BR and TriG44 derived from marine sea turtles showed a significantly high tolerance to HgCl_2 as compared to the three mammalian neural *** these neural cells,SK-N-SH represented the most sensitive cells to both chemical forms of mercury.

关键词： In vitro cytotoxicity Neural cell lines HgCl_2 MeHgCl

Understanding the Effects of Iatrogenic Management on Population health:A Medical Innovation Perspective

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China CDC weekly 2023年第27期5卷 614-618页

作者： Jian Yang Shuduo Zhou Xiangning Feng Ying Chen Yunxuan Hu Ming Xu Department of global health School of Public HealthPeking UniversityBeijingChina institute for global health and Development Peking UniversityBeijingChina

In this paper,we introduce an iatrogenesis intervention framework guided by medical innovation,which encompasses the objectives,influences of medical innovation on iatrogenesis,factors affecting various types of iatrogenesis,and strategies for controlling *** in medical innovation across various domains can bridge the patient safety implementation gap by uncovering,characterizing,refining,accelerating,scaling,extending,and mobilizing the external and internal conditions and factors that influence the control and elimination of iatrogenesis.

关键词： elimination scaling controlling

Assessing healthcare workers’knowledge and confidence in the diagnosis,management and prevention of Monkeypox

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World Journal of Clinical Cases 2025年第1期13卷 38-47页

作者： Epipode Ntawuyamara Thierry Ingabire Innocent Yandemye Polycarpe Ndayikeza Bina Bhandari Yan-Hua Liang Department of Dermatology Cosmetology and VenereologyShenzhen Hospital of Southern Medical UniversityShenzhen 518101Guangdong ProvinceChina Department of Dermatology and Venereology Kamenge Teaching HospitalUniversity of BurundiBujumbura 1020Burundi Department of Infectious Diseases Kamenge Teaching HospitalUniversity of BurundiBujumbura 1020Burundi General Directorate of healthcare Supply Modern and Traditional MedicineNutrition and RegistrationMinistry of Public Health and Fight Against HIV/AIDSBujumbura 1055Burundi Department of Epidemiology National Institute of Public HealthBujumbura 350Burundi General Directorate of Planification Ministry of Public Health and Fight Against HIV/AIDSBujumbura 1055Burundi

BACKGROUND Monkeypox(Mpox),is a disease of global public health concern,as it does not affect only countries in western and central *** To assess Burundi healthcare workers(HCWs)s’level of knowledge and confidence in the diagnosis and management of *** We conducted a cross-sectional study via an online survey designed mainly from the World health Organization course distributed among Burundi HCWs from June-July *** questionnaire comprises 8 socioprofessional-related questions,22 questions about Mpox disease knowledge,and 3 questions to assess confidence in Mpox diagnosis and *** data were analyzed via SPSS software version 25.0.A P value<0.05 was considered to indicate statistical *** The study sample comprised 471 HCWs who were mainly medical doctors(63.9%)and nurses(30.1%).None of the 22 questions concerning Mpox knowledge had at least 50%correct responses.A very low number of HCWs(17.4%)knew that Mpox has a *** confidence level to diagnose(21.20%),treat(18.00%)or prevent(23.30%)Mpox was low among *** confidence level in the diagnosis of Mpox was associated with the HCWs’age(P value=0.009),sex(P value<0.001),work experience(P value=0.002),and residence(P value<0.001).The confidence level to treat Mpox was significantly associated with the HCWs’age(P value=0.050),sex(P value<0.001),education(P value=0.033)and occupation(P value=0.005).The confidence level to prevent Mpox was associated with the HCWs’education(P value<0.001),work experience(P value=0.002),residence(P value<0.001)and type of work institution(P value=0.003).CONCLUSION This study revealed that HCWs have the lowest level of knowledge regarding Mpox and a lack of confidence in the ability to diagnose,treat or prevent *** is an urgent need to organize continuing medical education programs on Mpox epidemiology and preparedness for Burundi *** encourage future researchers to assess potential hesitancy toward Mpox vaccination and its asso

关键词： Monkeypox public health emergency of international concern healthcare workers Epidemic Preparedness Knowledge Confidence

Framework Construction and Application for global health Information Platform

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Wuhan University Journal of Natural Sciences 2015年第2期20卷 153-158页

作者： ZHOU Jing Lü Chaozhen JI Donghong LIANG Xiaohui school of Computer Wuhan University global health institute Wuhan University school of public health Wuhan University

In order to understand the global health related information rapidly and timely, a global health information platform based on big data from internet is constructed. In this paper, we introduce the framework and application of the global health information platform. The functions of information platform mainly include two aspects： to analyze and disseminate theoretical and technological progress of the main research fields in global health and to monitor real-time emergencies, epidemic situation and hot topics related to the field of global health. The objective of this research is to establish a Chinese-English bilingual information platform in the global health field. The platform would help academic researchers understand and master global health progress in time; acquire information of global health comprehensively, accurately and dynamically; and eventually help deal with the risk of global diseases, formulate appropriate health policies and actively participate in the international global health affairs.

关键词： global health information platform basic framework application

Investigation of College Students' Mental health Status via Semantic Analysis of Sina Microblog

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Wuhan University Journal of Natural Sciences 2015年第2期20卷 159-164页

作者： LIANG Xiaohui GU Siqi DENG Jiayuan GAO Zhaixing ZHANG Zhonghua SHEN Dezhong school of public health Wuhan University global health institute Wuhan University school of Computer Wuhan University

The objective of this study is to understand the current mental status of college students in China's Mainland. In this study, 60 thousand college students＇ microblog content from January 2014 to June 2014 was collected. An emotional energy level, which was developed by a psychologist David R Hawkins, was taken as a basis for ontology database to divide the student＇s emotion into three parts--positive, negative and neutral status. An ontology-based semantic analysis method was used to analyze the microblog data. The result shows that 46.38% of Sina microblog data reflects positive psychological status, and the ratios of neutral and negative psychological status are 19.77% and 33.85%, respectively. It means that almost one third microblog reflects some negative mentality. The semantic analysis of the big data suggests that most students have healthy mental status, and the negative status of the students should not be ignored.

关键词： college students big data Sina microblog mental health ontology

Estimated Average Glandular Dose for 1,828 Mammography Procedures in China: A Multicenter Study

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Biomedical and Environmental Sciences 2019年第4期32卷 242-249页

作者： DU Xiang WANG Jin ZHU Bao Li Jiangsu Provincial Center for Disease Prevention and Control Center for global health School of Public HealthNanjing Medical University

Objective To understand the distribution of the average glandular dose(AGD) in mammography by investigating 1,828 exposure parameters of 8 mammography machines in three cities, by using random sampling. Methods A survey of 8 mammography machines in three different cities, sampled using stratified random sampling methods, was performed, and 1,828 mammography exposure parameters were recorded. Incident air kerma(k) was measured by Quality-Assurance(QA) dosimeters, and AGD was calculated by series conversion coefficients based on a 3D detailed Monte Carlo breast model, published by Wang et al. Results The distribution of compressed breast thickness(CBT) fitted a normal distribution, while that of AGD fitted a skewed distribution. The mean value of CBT in a medio-lateral oblique(MLO) view was about 5.6% higher than that in the craniocaudal(CC) view, with significant statistical difference; mean value of AGD and CBT in the sample was 1.3 mGy and 4.6 cm, respectively. The AGD trended upward with increasing CBT, similar to the results of other researches. Conclusion The mean AGD and CBT levels in our study for mammography practice in China were 1.3 mGy and 4.6 cm, respectively. AGD is influenced by manufacturer-specific variation as machine response to CBT changes and target/filter combination. The present study can provide evidence for establishing a diagnostic reference level in China.

关键词： Medical radiation Mammography Compressed breast thickness Average glandular dose

A Review of Pathogens Transmitted by the Container-Inhabiting Mosquitoes, Aedes Albopictus, A global public health Threat

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China CDC weekly 2023年第44期5卷 984-990页

作者： Wenrong Zhang Jinna Wang Qinmei Liu Zhenyu Gong school of public health Hangzhou Medical CollegeHangzhou CityZhejiang ProvinceChina institute of Infectious Disease Prevention and Control Zhejiang Provincial Center for Disease Control and PreventionHangzhou CityZhejiang ProvinceChina

ABSTRACT Dengue virus(DENV),Chikungunya virus(CHIKV),and Zika virus(ZIKV)are highly pathogenic human arboviruses transmitted by the Aedes(Stegomyia)albopictus(Skuse)(Diptera:Culicidae)or *** *** arboviruses are responsible for causing fever,hemorrhagic conditions,and neurological diseases in humans post-bite from an infected Aedes *** the past 80 years,the *** has infested every habitable continent.

关键词： diseases hemorrhagic Container

The Sendai Framework for Disaster Risk Reduction and Its Indicators——Where Does health Fit in?

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International Journal of Disaster Risk Science 2017年第2期8卷 150-155页

作者： Rishma Maini Lorcan Clarke Kevin Blanchard Virginia Murray public health Registrar in global Disaster Risk Reduction Public Health England Research Analyst Intern in global Disaster Risk Reduction Public Health England Senior Environmental Scientist in global Disaster Risk Reduction Public Health England public health Consultant in global Disaster Risk Reduction Public Health England United Nations International Strategy for Disaster ReductionScientific and Technical Advisory Group Integrated Research on Disaster Risk Reduction Scientific Committee

The Sendai Framework for Disaster Risk Reduction 2015–2030 recognizes the strong connection between health and disasters and promotes the concept of health resilience *** of the seven global targets stated in the Sendai Framework are directly related to health in terms of reducing disaster mortality,the number of affected people,disaster damage to critical infrastructure,and disruption of basic services such as health *** Sendai Framework also maintains close coordination with other United Nations landmark agreements relevant to health such as the Sustainable Development ***,the measurement of healthrelated indicators is *** arise,for example,in linking deaths to disasters because of the complex interplay between exposure,risk,vulnerability,and *** lack of a universal classification of disasters also means that recording of health data in disasters is not *** the guidelines to enable data onthe indicators to be collected and reported to support the Sendai targets requires detailed thinking,time,and consultation with a diverse range of *** collaboration and partnership will be vital to achieving success.

关键词： Disaster risk reduction global health targets health indicators Sendai Framework