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Oncology Research 2024年第2期32卷 421-432页

作者： SEUNG-HEE GWAK JUHYUN LEE EUNJI OH DOHYUN LEE WONSHIK HAN JONGMIN KIM KYONG-TAI KIM Department of Life Sciences Pohang University of Science and TechnologyPohang37673Korea R&D Center NovMetaPharma Co.Ltd.Pohang37668Korea Department of Surgery and Cancer Research institute Seoul National University College of MedicineSeoul03080Korea Generative Genomics Research Center Global Green Research&Development CenterHandong Global UniversityPohang37554Korea

Genetic information is transcribed from genomic DNA to mRNA,which is then translated into threedimensional *** can undergo various post-transcriptional modifications,including RNA editing that alters mRNA sequences,ultimately affecting protein *** this study,RNA editing was identified at the 499th base(c.499)of human vaccinia-related kinase 2(VRK2).This RNA editing changes the amino acid in the catalytic domain of VRK2 from isoleucine(with adenine base)to valine(with guanine base).Isoleucine-containing VRK2 has higher kinase activity than the valine-containing VRK2,which leads to an increase in tumor cell *** we reported that VRK2 directly interacts with dystrobrevin-binding protein(dysbindin)and results in reducing its ***,we demonstrate that isoleucine-containing VRK2 decreases the level of dysbindin than valinecontaining *** interacts with cyclin D and thereby regulates its expression and *** reduction in the level of dysbindin by isoleucine-containing VRK2 further enhances the cyclin D expression,resulting in increased tumor growth and reduction in survival *** has also been observed that in patient samples,VRK2 level was elevated in breast cancer tissue compared to normal breast ***,the isoleucine form of VRK2 exhibited a greater increase in breast cancer ***,it is concluded that VRK2,especially dependent on the 167th variant amino acid,can be one of the indexes of tumor progression and proliferation.

关键词： VRK2 Kinase activity Breast cancer Tumor RNA editing Cell proliferation Cell growth

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Advances in Intermediates for the Solution-Processing of Perovskite Films

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CCS Chemistry 2024年第3期6卷 585-603页

作者： Ziqiu Ren Binyang Tuo Na Wang Junjie Ma Pengwei Li Yiqiang Zhang Yanlin Song Henan institute of Advanced Technology College of ChemistryZhengzhou UniversityZhengzhou 450052 Key Laboratory of green Printing Institute of ChemistryChinese Academy of Sciences(ICCAS)Beijing Engineering Research Center of Nanomaterials for Green Printing TechnologyNational Laboratory for Molecular Sciences(BNLMS)Beijing 100190

Owing to its superior efficiency and low cost,the solution-processable perovskite has rapidly become the latest favorite material in the field of *** solution processing significantly reduces the threshold and cost of perovskite solar cells,the intricate composition and nonequilibrium nucleation of the perovskite precursor can result in leaky *** precise control of perovskite nucleation and orientation is a fundamental prerequisite for achieving high-quality perovskite photoactive *** this process,the intermediate species that widely exists either in the precursor or the asprepared film acts as a transitional state for perovskite nucleation and growth from solution to solid,presenting an opportunity for controlling perovskite ***,we present an overview of the advancements in intermediates for solution-processing perovskite films to gain insights into the growth and manipulation of polycrystalline perovskite films.

关键词： perovskite solar cells intermediates solvent engineering phase transformation nucleation and growth

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A review of low-carbon technologies and projects for the global cement industry

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Journal of Environmental Sciences 2024年第2期136卷 682-697页

作者： Yangyang Guo Lei Luo Tingting Liu Liwei Hao Yinming Li Pengfei Liu Tingyu Zhu CAS Key Laboratory of green Process and Engineering Institute of Process EngineeringInnovation Academy for Green ManufactureChinese Academy of SciencesBeijing 100190China Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China State Key Laboratory of Solid Waste Reuse for Building Materials Beijing Building Materials Academy of Sciences ResearchBeijing 100041China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou 341000China

Carbon dioxide(CO_(2))emissions from the cement industry account for 26%of the total industrial emissions,and the need to develop low-carbon techniques within the cement industry is extremely ***-carbon projects and technologies for the cement industry in different regions and countries have been thoroughly reviewed in this manuscript,and the low-carbon development concept for each county has been *** developing countries such as China and India,energy saving and efficiency enhancement are currently the key points,while for developed countries and regions such as Europe,more efforts have been focused on carbon capture,utilization,and storage(CCUS).global CCUS projects have been previously conducted,and the majority of CCUS projects are currently performed in Europe where major projects such as the CEMCAP,CLEANKER,and IEILAC projects represent the latest research progress in cement production technologies and low-carbon technologies for the global cement *** development of low-carbon cement technologies has changed from focusing on the end point to instead focusing on the source and process through the exploration of hydrogen and solar energies,and more disruptive and original technologies are expected to be developed,particularly in the cement industry in China.

关键词： Cement industry CO_(2)emissions Low carbon development Projects Carbon capture utilization and storage

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A widely used nonionic surfactant with desired functional groups as aqueous electrolyte additives for stabilizing Zn anode

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Rare Metals 2024年第8期43卷 3692-3701页

作者： Yue-Xian Song Xiao-Feng Wang Cai-Bin Liu Kai-Xuan Guo Xu-Huan Guo Xiao-Bin Zhong Yao-Hui Zhang Kai Wang Hui-Juan Guo Li-Xin Zhang Jun-Fei Liang School of Energy and Power Engineering North University of ChinaTaiyuan 030051China Key Laboratory of green Chemical Process of Ministry of Education Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical TechnologySchool of Chemical Engineering and PharmacyWuhan Institute of TechnologyWuhan 430073China Shanxi Provincial Key Laboratory for High Performance Battery Materials and Devices Taiyuan 030051China

Aqueous Zn-ion batteries(AZIBs) have emerged as potential candidates for Li-ion batteries due to their intrinsic safety and high ***,metallic Zn anodes encounter dendrite growth and water-induced corrosion,rendering poor stability and severe irreversibility at the electrode/electrolyte interface during *** stabilize the Zn anode,we report a low-cost and effective nonionic surfactant,Tween-20 polymer,as an electrolyte additive for *** Tween-20,sequential oxyethylene groups tended to be preferentially adsorbed on the Zn electrode to form a shielding layer for regulating uniform Zn ***,the hydrophobic hendecyl chains prevented H_(2)O-induced corrosion on the Zn anode *** from the desired functional groups,when only trace amounts of Tween-20(0.050 g·L^(-1)) were used,the Zn anode displayed good cycling stability over 2170 h at10 mA·cm^(-2) and a high average Coulombic efficiency of98.94% over 1000 *** Tween-20 polymer can also be effectively employed in MnO_(2)/Zn full *** their toxicity,price and amount of usage,these surfactant additives provide a promising strategy for realizing the stability and reversibility of high-performance Zn anodes.

关键词： Zn anode Dendrite growth Tween-20 polymer Surfactant additive Aqueous electrolyte

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Market-based solution in China to finance the clean from the dirty

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Fundamental Research 2024年第2期4卷 324-333页

作者： Haoqi Qian Rong Ma Libo Wu institute for global Public Policy Fudan UniversityShanghai 200433China LSE-Fudan Research Centre for global Public Policy Fudan UniversityShanghai 200433China School of Economics Fudan UniversityShanghai 200433China Shanghai institute for Energy and Carbon Neutrality Strategy Fudan UniversityShanghai 200433China

Financial incentives play a key role in promoting renewable energy investments that can help China achieve the‘dual carbon’*** national emissions trading scheme(ETS)and the renewable energy portfolio standard(RPS)are two existing market-based policy instruments that can generate stable expected returns for low-carbon *** paper studies the interactive distribution effects of these two market-based *** use the micro-level thermal power plant data to investigate the abatement effects of the national ETS,in which the details show that the existing rate-based ETS will result in higher negative impacts on power units,whose installed capacities are smaller than 400 *** interactive distribution effects between the two markets will occur when the permit allocation standards of the national ETS become stricter than the existing *** in Eastern China and Northern China will face high pressure on costs in both ETS and RPS *** the levels of the permit allocation standards are set as 70%of the existing ones and the carbon price is assumed to be 200 yuan/ton in 2030,the annual market size of the national ETS will be nearly 100 billion yuan,and the annual market size is predicted to be 250 billion *** the existing rate-based national ETS,the China Certified Emission Reduction(CCER)mechanism will have an offsetting effect,which should be taken into serious consideration during the policy-making processes in the future.

关键词： Emission trading scheme Renewable energy portfolio standard green finance Policy interactions China certified emission reduction Distribution effect

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Synthesis of spherical nano-ZSM-5 zeolite with intergranular mesoporous for alkylation of ethylbenzene with ethanol to produce m-diethylbenzene

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Chinese Journal of Chemical Engineering 2024年第3期67卷 298-309页

作者： Siyue Wang Jinhong Li Qingxin Xu Shengjie Song Yu'ni Jiang Lidong Chen Xin Shi Weiguo Cheng Faculty of Chemistry and Chemical Engineering Liaoning Normal UniversityDalian 110629China Beijing Key Laboratory of Ionic Liquids Clean Process Key Laboratory of Green Process and EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China

Catalytic synthesis of m-diethylbenzene(m-DEB)through alkylation of ethylbenzene(EB)may be a promising alternative route in comparison with traditional rectification of mixed DEB,for which the top priority is to develop efficient and stable heterogeneous ***,the spherical nano-ZSM-5 zeolite with abundant intergranular mesoporous is synthesized by the seed-mediated growth method for alkylation of EB with ethanol to produce *** results show that the spherical nano-ZSM-5 zeolite exhibits better stability and higher alkylation activity at a lower temperature than those of commercial micropore *** then,the spherical nano-ZSM-5 is further modified by La_(2)O_(3) through acid treatment followed by immersion *** acid treatment causes nano-ZSM-5 to exhibit the increased pore size but decreased the acid sites,and subsequent La_(2)O_(3) loading reintroduces the weak acid *** a result,the HNO_(3)-La_(2)O_(3)-modified catalyst exhibits a slight increase in EB conversion and DEB yield in comparison with unmodified one,and meanwhile,it still maintains high m-DEB *** catalyst after acid treatment achieves higher catalytic stability besides maintaining the high alkylation activity of EB with *** present study on the spherical nano-HZSM-5 zeolite and its modification catalyst with excellent alkylation ability provides new insights into the production of mDEB.

关键词： Zeolite Modification Alkylation reaction m-diethylbenzene Catalyst Fixed-bed

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Co-influence of the start of thermal growing season and precipitation on vegetation spring green-up on the Tibetan Plateau

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Advances in Climate Change Research 2024年第2期15卷 327-337页

作者： Chen-Peng WANG Meng-Tian HUANG Pan-Mao ZHAI State Key Laboratory of Severe Weather and institute of global Change and Polar Meteorology Chinese Academy of Meteorological SciencesBeijing 100081China University of Chinese Academy of Sciences Beijing 100049China

The climate in the Tibetan Plateau(TP)has undergone significant change in recent decades,mainly in thermal and water conditions,which plays a crucial role in phenological changes in vegetation spring ***,how the start of the thermal growing season(SOS-T)and the start of the rainy season(SORS)as key climatic factors affect vegetation green-up remains *** that these factors characterize thermal and water conditions required for vegetation green-up,this study investigated changes in the SOS-T and SORS from 1961 to 2022,using observation-based datasets with long time *** found that the SOS-T and SORS have advanced across the TP in 1961-2022 and have shown a spatial pattern of advancement in the east and delay in the west in ***,the co-effect of temperature and precipitation change on the start of vegetation growing season(SOS-V)in 2000-2022 was *** across TP,the SOS-V had an early onset of 1.3 d per decade during 2000-2022,corresponding to advanced SOS-T and ***,the SOS-V generally occurred nearly at the same time as the SOS-T in the high-altitude meadow region.A substantial delay in the SOS-V relative to the SOS-T was observed in the desert,shrub,grassland and forest regions and generally kept pace with the ***,for 50%of the vegetated regions on the TP,inter-annual variation in the delay in the SOS-V relative to the SOS-T was dominated by precipitation change,which was profound in warm-climate *** study highlights the co-regulation of precipitation and temperature change in the SOS-V in different vegetation cover regions in the TP,offering a scientific foundation for comprehending the impact of climate change and prospects for vegetation phenology on the TP.

关键词： Tibetan Plateau Start of growing season Temperature Precipitation Climate change

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Flexible bidirectional pulse charging regulation achieving long-life lithium-ion batteries

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Journal of Energy Chemistry 2024年第9期96卷 59-71页

作者： Xiaodong Xu Shengjin Tang Xuebing Han Languang Lu Yudi Qin Jiuyu Du Yu Wu Yalun Li Chuanqiang Yu Xiaoyan Sun Xuning Feng Minggao Ouyang Rocket Force University of Engineering Xi’an 710025ShaanxiChina State Key Laboratory of Intelligent green Vehicle and Mobility School of Vehicle and MobilityTsinghua UniversityBeijing 100084China School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China

Typical application scenarios,such as vehicle to grid(V2G)and frequency regulation,have imposed significant long-life demands on lithium-ion ***,we propose an advanced battery life-extension method employing bidirectional pulse charging(BPC)*** traditional constant current charging methods,BPC strategy not only achieves comparable charging speeds but also facilitates V2G frequency regulation *** significantly enhances battery cycle ampere-hour throughput and demonstrates remarkable life extension *** this interesting conclusion,adopting model identification and postmortem characterization to reveal the life regulation mechanism of BPC:it mitigates battery capacity loss attributed to loss of lithium-ion inventory(LLI)in graphite anodes by intermittently regulating the overall battery voltage and anode potential using a negative charging ***,from the perspective of internal side reaction,the life extension mechanism is further revealed as inhibition of solid electrolyte interphase(SEI)and lithium dendrite growth by regulating voltage with a bidirectional pulse current,and a semi-empirical life degradation model combining SEI and lithium dendrite growth is developed for BPC scenarios health management,the model parameters are identified by genetic algorithm with the life simulation exhibiting an accuracy exceeding 99%.This finding indicates that under typical rate conditions,adaptable BPC strategies can extend the service life of LFP battery by approximately 123%.Consequently,the developed advanced BPC strategy offers innovative perspectives and insights for the development of long-life battery applications in the future.

关键词： Lithium-ion battery Long-life regulation Bidirectional pulse charging Mechanism identification

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Assessing Financial Management Practices and Accounting Mechanisms in Agricultural Cooperatives:A Case Study From Nepal

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Management Studies 2024年第3期12卷 146-171页

作者： Chiranjeewee Khadka Ghanshyam Pandey Arbin Poudel Eva Cudnilova global Change Research institute CAS BrnoCzech Republic University of South Bohemia ČeskéBudějoviceCzech Republic Pokhara Campus PokharaNepal green Foundation Nepal KathmanduNepal

The study focuses on assessing the financial management practices and accounting mechanisms in agricultural cooperatives in Tulsipur Sub-Metropolitan,Dang District,Nepal with a focus on understanding their implications for financial performance and organizational *** sample size of total cooperatives(n=46)was divided into Savings and Credit Cooperatives(n=18)and Multipurpose Cooperatives(n=28),respectively,with a total number of respondents(n=138)categorized into managing directors,employees,and general *** a mixed-methods approach that combines quantitative analysis of financial data with qualitative insights gathered through interviews and surveys,the study emphasizes the importance of modern financial practices,improved reporting mechanisms,and relevant staff training for long-term *** include the integration of criteria and evaluation tools to assess cooperative performance,with Hamro Pahunch Multipurpose Cooperative identified as a high *** the need for robust financial management strategies to navigate the complexity of the agricultural sector,manage risks,and achieve sustainable development,the study notes frequent preparation of financial management reports on a monthly and annual basis,and predominantly annual accounting *** cooperatives are using computerized models to present financial positions,but face challenges such as lack of marketing infrastructure,cooperative skills,and technical ***,the study advocates for educating policy makers,cooperative leaders,practitioners and stakeholders on the role of effective financial management and accounting in enhancing the resilience,expansion and socio-economic impact of agricultural cooperatives,thereby fostering their long-term prosperity and viability as drivers of rural development and empowerment.

关键词： accounting mechanisms agricultural cooperatives financial management evaluation criteria and performance transparency

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Characteristics of Rock Mechanics Response and Energy Evolution Regime of Deep Reservoirs in the Bozhong Sag,Bohai Bay Basin

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Energy Engineering 2024年第9期121卷 2505-2524页

作者： Suogui Shang Kechao Gao QingbinWang Xinghua Zhang Pengli Zhou Jianhua Li Peng Chu Tianjin Branch of CNOOC Limited Tianjin300459China Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyShenzhen UniversityShenzhen518060China College of Civil and Transportation Engineering Shenzhen Key Laboratory of Deep Engineering Sciences and Green EnergyShenzhen UniversityShenzhen518060China

Hydraulic fracturing is a mature and effectivemethod for deep oil and gas production,which provides a foundation for deep oil and gas *** of the key aspects of implementing hydraulic fracturing technology lies in understanding mechanics response characteristics of rocks in deep reservoirs under complex stress *** this work,based on outcrop core samples,high-stress triaxial compression tests were designed to simulate the rock mechanics behavior of deep reservoirs in Bozhong ***,this study analyzes the deformation and damage law for rock under different stress ***,with a particular focus on combining energy dissipation theory to further understand damage law for deep *** experimental results show that regardless of stress conditions,the process of deformation/failure of deep-seated reservoirs goes through five stages:Fracture compaction,newfracture formation,stable fracture expansion,unstable fracture expansion,and post-peak residual *** different stress conditions,the energy change laws of specimens are *** energy dissipation process of rocks corresponds closely to the trend of deformation-failure curve,then displays distinctive stage ***,in stage of rock fracture compaction,the input energy curve is approximately coincident with the elastic strain energy curve,while the dissipation energy curve remains near *** the increase of strain,the growth rate of elastic strain energy increases gradually,but with the deformation entering the crack propagation stage,the growth rate of elastic strain energy slows down and the dissipation energy increases ***,in the post-peak stage,rock fracture releases a lot of energy,which leads to the sharp decline of elastic strain energy *** addition,the introduction of damage variable D quantifies the analysis of the extent of failure for *** the process of increasing strain,rock damage exhibits nonlinear

关键词： Deep rock mechanics triaxial compression energy dissipation damage variable

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