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Grain & Oil Science and Technology 2021年第2期4卷 54-61页

作者： Qian Li Xiaoman Zhu Henan Key Laboratory of Cereal and Oil food Safety inspection and Control College of Food Science and EngineeringHenan University of Technology

To study the structure-antifungal activity of vanillin against Aspergillus flavus(***),the susceptibilities of *** to vanillin and its isomers(o-vanillin,2-hydroxy-4-methoxybenzaldehyde(HMB),2-hydroxy-5-methoxybenzaldehyde)and the possible antifungal mechanisms have been *** the four volatile aldehydes could inhibit the germination of spores,and the minimum inhibitory concentrations(MICs)of them were in this order:vanillin(200μg/mL),o-vanillin(100μg/mL),2-hydroxy-5-methoxybenzaldehyde(100μg/mL),HMB(70μg/mL).The minimum fungicidal concentrations(MFCs)of them were in this order:vanillin(240μg/mL),o-vanillin(160μg/mL),HMB(140μg/mL),2-hydroxy-5-methoxybenzaldehyde(140μg/mL).Spore size was arrested at 0 h with the treatment of the four volatile *** of the four volatile aldehydes on the cell wall and cell membrane integrity of A flavus were observed by calcofluor white(CW)staining and propidium iodide(PI)*** results showed that HMB exerted the strongest antifungal and fungicidal effects on the growth of *** four volatile aldehydes had little influence on cell wall integrity after 3-hour treatment,however,they could strongly damage the cell membrane *** the four volatile aldehydes could effectively prevent the growth of *** on peanut *** antifungal mechanisms of the four volatile aldehydes provide theoretical foundations for their development of new antifungal agents.

关键词： Aspergillus flavus Vanillin o-Vanillin HMB 2-Hydroxy-5-methoxybenzaldehyde Antifungal mechanism

Human Toxicosis Caused by Moldy Rice Contaminated with Fusarium and T-2 Toxin

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Biomedical and Environmental Sciences 1993年第1期6卷 65-70页

作者： Z G Wang J N Feng Z Tong Zhejiang Institute of food Safety Control and inspection Hangzhou China.

This is the first report on human toxicosis in China caused by moldy rice contaminated with Fusarium and T-2 toxin due to heavy rainfall during rice harvest season. One hundred and sixty-five persons ate the moldy rice and ninety-seven persons fall ill of food poisoning. The incidence was 58.8% and latent period was 10-30 min. The chief symptoms were nausea, dizziness, vomiting, chills, abdominal distension, abdominal pain, thoracic stuffiness and diarrhea. The fungi isolated from the moldy rice were predominantly Fusarium heterosporum (F. heterosporum) and F. graminearum. T-2 toxin was found in these moldy rice and the highest level was 420 ppb. The chief causative agent of intoxication was T-2 toxin.

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Effects of different doses of glucose and fructose on central metabolic pathways and intercellular wireless communication networks in humans

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food Science and Human Wellness 2024年第4期13卷 1906-1916页

作者： Dingqiang Lu Yujiao Liu Miao Zhao Shuai Yuan Danyang Liu Xinqian Wang Yixuan Liu Yifei Zhang Ming Li Yufeng Lü Guangchang Pang Ruijuan Ren College of Biotechnology&food Science Tianjin University of CommerceTianjin Key Laboratory of Food BiotechnologyTianjin 300314China Tianjin Institute for food Safety inspection Technology Tianjin 300134China

Fructose and glucose are often widely used in food processing and may contribute to many metabolic *** observe the effects of different doses of glucose and fructose on human metabolism and cellular communication,volunteers were given low,medium,and high doses of glucose and *** cytokines,glucose,lactate,nicotinamide adenine dinucleotide(NADH)and metabolic enzymes were assayed,and central carbon metabolic pathway networks and cytokine communication networks were *** results showed that the glucose and fructose groups basically maintained the trend of decreasing catabolism and increasing anabolism with increasing *** with glucose,low-dose fructose decreased catabolism and increased anabolism,significantly enhanced the expression of the inflammatory cytokine interferon-γ(IFN-γ),macrophage-derived chemokine(MDC),induced protein-10(IP-10),and eotaxin,and significantly reduced the activity of isocitrate dehydrogenase(ICDH)and pyruvate dehydrogenase complexes(PDHC).Both medium and high doses of fructose increase catabolism and anabolism,and there are more cytokines and enzymes with significant ***,multiple cytokines and enzymes show strong relevance to metabolic regulation by altering the transcription and expression of enzymes in central carbon metabolic ***,excessive intake of fructose should be reduced to avoid excessive inflammatory responses,allergic reactions and autoimmune diseases.

关键词： Fructose Glucose Central carbon metabolic pathway Metabolic enzymes Cytokine network

Risk Assessment of MOAH and MOSH in Infants and Young Children

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Biomedical and Environmental Sciences 2019年第2期32卷 130-133页

作者： ZHU Lei ZHANG Hong CHEN Yan Fen PAN Jing Jing LIU Ai Dong PAN Feng ZHANG Jian Bo ZHONG Huai Ning China National Centre for food Safety Risk Assessment Guangdong inspection and Quarantine Technology Centre

Mineral oil hydrocarbons(MOH) in food may come from both contamination and various intentional uses in food production. MOH is widely used in food contact materials and food additives. It comprises complex mixtures, i... 详细信息

关键词： In Risk Assessment Young Children

National food Contamination Monitoring Programmes-Levels of Mercury, Lead and Cadmium in Chinese foods

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Biomedical and Environmental Sciences 1994年第4期7卷 362-368页

作者： YANG HUI-FEN LUO XUE-YUN SHEN WEN ZHOU ZHONG-FU JIN CHUANG-YU YU FENGC AND LIANG CHUN-SUI(Institute of food Safety Control and inspection, Ministry of Public Health, 7 Pan Jia Yuan, Beijing 100021, China Shanghai Municipal Institute of food Safety Co Institute of food Safety Control and inspection Ministry of Public Health Beijing China.

Six hundred and thirty-four food samples of six kinds were collected from Beijing,Shanghai, Jiangsu, Sichuan, Jilin and Guangdong areas, China and Hg, Pb, Cd contents were determined. The results showed that their levels in the Chinese foods were low; their levels in meat, egg, milk and fish were generally below the national hygienic standard. The average daily dietary intake of Hg, Pb, Cd were 7.25 μg, 103.77μg and 30.72 μg respectively and they were all less than the ADI established by WHO

关键词： National food Contamination Monitoring Programmes-Levels of Mercury WHO Lead and Cadmium in Chinese foods

Antifungal properties and mechanisms of three volatile aldehydes(octanal,nonanal and decanal)on Aspergillus flavus

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Grain & Oil Science and Technology 2021年第3期4卷 131-140页

作者： Qian Li Xiaoman Zhu Yanli Xie Jingmeng Liang Henan Key Laboratory of Cereal and Oil food Safety inspection and Control College of Food Science and EngineeringHenan University of TechnologyZhengzhou 450001China

The harmof Aspergillus flavus(***)and aflatoxin is a severe food safety problemworldwide,which causes huge economic losses every ***,it is urgent to control the growth of *** and the biosynthesis of ***-derived natural compounds are superior to synthetic fungicide in inhibiting the growth of *** benefiting from their high safety to the environment,humans and stock,and low *** study aimed to evaluate the antifungal effects and potential antifungal mechanisms of three plant-derived compounds(octanal,nonanal and decanal)against *** determined the minimum inhibitory concentrations(MICs)and action mechanism of the three volatile aldehydes on *** and also performed calcofluor white(CW)staining for visualizing the distribution of *** respiration metabolism and the pathogenicity on maize kernels were also carried out to evaluate the efficacy of the three volatile aldehydes on the growth of *** results showed that the three volatile aldehydes could inhibit the germination of spores and mycelial growth of ***,the MICs on spores and mycelia were:octanal(1.0 and 0.5μL/mL),nonanal(0.5 and 2.0μL/mL),and decanal(1 and 5μL/mL).The three volatile aldehydes could strongly damage the integrity of both the cell wall and the cell membrane of ***,they could decrease the content of total lipid and inhibit respiration metabolism of *** *** of in vitro antifungal test showed that all the three volatile aldehydes could effectively prevent the growth of *** on maize *** study revealed that octanal,nonanal and decanal could effectively inhibit the growth of *** both in culture medium and on maize kernels to different *** results confirmed that the plant-derived compounds could be developed into promising antifungal agents applied in the preservation of *** study provides a theoretical basis for the research and application of potential antifungal agents.

关键词： Aspergillus flavus Octanal Nonanal Decanal Antifungal mechanism

Safety Evaluation of Irradiated foods in China: A Condensed Report

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Biomedical and Environmental Sciences 1989年第1期2卷 1-6页

作者： YIN DAI Institute of food Safety Control and inspection, Ministry of Public Health, Beijing, China Institute of food Safety Control and inspection Ministry of Public Health Beijing China.

Eight trials, with 439 human volunteers who consumed irradiated foods including rice, potatoes, mushrooms, peanuts, and Chinese sausages, as well as diets composed of multiple irradiated foods (irradiated at dosages of 0.2 to 8 kGy) that accounted for 60-66％ of the entire diet, were carried out for 2-3 months according to a unified protocol. No adverse effects on body weight, blood pressure, ECG, hematology, blood enzyme activities, serum lipids, or blood or urine 17-hydroxycortisol contents and no chromosomal aberration of peripheral blood lymphocytes were found. It is especially worthwhile to note that there was no change in the polyploidy after consumption of irradiated diets. On the basis of these results and a comprehensive analysis of the physical and chemical characteristics of irradiated foods, temporary hygienic standards for irradiated rice, potatoes, onions, garlic, Chinese sausages, peanuts, and mushrooms were promulgated by the Chinese Ministry of Public Health. 1989 Academic Press, Inc.

关键词： Safety Evaluation of Irradiated foods in China In A Condensed Report

Multiarm Star Poly(ε-caprolactone) with Hyperbranched Polyamidoamine as Core Capable of Selective Accommodating Cationic or Anionic Guests

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Chinese Journal of Polymer Science 2015年第6期33卷 920-930页

作者： Chen Zhan Si Li Jin Cui 陈宇 department of Chemistry School of SciencesTianjin Universityand Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) National foodstuff inspection Center Tianjin Product Quality Inspection Technology Research Institute

Hyperbranched polyamidoamines （HPAs） were directly employed as macroinitiators to initiate the Sn（Oct）2 catalyzed ring-opening polymerization of ε-caprolactone （CL）, resulting in multiarm star copolymers with poly（6- caprolactone）（PCL） as shells and HPA as core （HPA-b-PCL）. From 1H-NMR characterization it was deduced that both the primary amines and the secondary amide groups of HPAs could initiate the CL polymerization, and the initiation efficiency increased when more CL monomers were fed. The average arm-numbers of the obtained stars were in the range of 115-353. Differential scanning calorimetry measurements demonstrated that the melting and crystallization temperatures, fusion and crystallization enthalpy and the degree of crystallinity of the star polymers increased as the PCL arm length increased. HPA- b-PCL stars could be used as nanocarriers to efficiently accommodate anionic dyes at acidic condition, while load cationic dyes at basic condition. Compared with the dye-loading behavior of multiarrn star PCL with the neutral hyperbranched polyglycerol as core, it was deduced that HPA-b-PCL nanocarriers accommodated anionic dyes using the HPA core, while loaded cationic dyes using both the HPA core and the PCL shell. Dynamic light scattering analyses also supported such deduction. Furthermore, HPA-b-PCL nanocarriers could selectively load the anionic Eosin Y or the cationic methylene blue from their mixture at pH = 6 or 9, respectively, realizing their separation.

关键词： Nanocarrier Hyperbranched Polyamidoamine Poly(ε-caprolactone) Star polymers.

Influence of laser re-melting and vacuum heat treatment on plasma-sprayed FeCoCrNiAl alloy coatings

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Journal of Iron and Steel Research International 2017年第12期24卷 1199-1205页

作者： Dan-yang Lin Nan-nan Zhang Bin He Bing-qian Jin Yue Zhang De-yuan Li Fu-yu Dong department of Material Science and Engineering Shenyang University of Technology department of Pipeline Shenyang Institute of Special Equipment Inspection & Research

FeCoCrNiAl high entropy alloy coatings were prepared by supersonic air-plasma *** coatings were post-treated by vacuum heat treatment at 600 and 900°C,and laser re-melting with 300 W,respectively,to study the influence of different treatments on the structure and properties of the *** phase constitution,microstructure and microhardness of the coatings after treatments were investigated using X-ray diffraction,scanning electron microscopy and energy dispersive *** showed that the as-sprayed coatings consisted of pure metal and *** AlNi;phase was obtained after the vacuum heat treatment process.A body-centered cubic structure with less AlNi;could be found in the coating after the laser re-melting *** average hardness values of the as-sprayed coating and the coatings with two different temperature vacuum heat treatments and with laser re-melting were 177,227,266 and 682 HV,*** suggests that the vacuum heat treatment promoted the alloying process of the coatings,and contributed to the enhancement of the coating wear *** laser re-melted coating showed the best wear resistance.

关键词： Plasma spray High entropy alloy Vacuum heat treatment Laser re-melting FeCoCrNiAl alloy coating

SYSTHESIS OF DOUBLE-HYDROPHILIC CORE-SHELL TYPE MULTIARM STAR COPOLYMER POLYETHYLENIMINE-block-POLY(2-HYDROXYETHYL METHACRYLATE)

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Chinese Journal of Polymer Science 2013年第7期31卷 1046-1055页

作者： Qiang Tang Fa Cheng Jin Cui 陈宇 School of Chemical and Environmental Engineering Hubei University of Technology department of Chemistry School of SciencesTianjin University National foodstuff inspection Center Tianjin Product Quality Inspection Technology Research Institute

Multiarm star block copolymers hyperbranched polyethylenimine-b-poly（2-hydroxyethyl methacrylate）（HPEI-b- PHEMA） with average 28 PHEMA arms have been prepared by atom transfer radical polymerization （ATRP） of HEMA in a mixed solvent of methanol and water using a core-first strategy. The hyperbranched macroinitiator employed was prepared on the basis of well-defined hyperbranched polyethylenimine with Mw/Mn of 1.04 by amidation with 2-bromo-isobutyryl bromide. The polymerization condition was optimized to prepare star copolymers with narrow dispersity, and the variables included the volume ratio of methanol to water, the molar ratio of initiating site to CuC1 and the molar ratio of [CuCl]：[CuBr2]. Under the optimized polymerization condition, the lowest Mw/Mn value of the obtained star copolymers was around 1.3. Kinetic analysis showed that an induction period existed in the polymerization of HEMA. After this induction period, a linear dependence of ln（[M]0/[M]t） on time was observed. The obtained HPEI-b-PHEMA could adsorb hydrophilic molecules. The comparison with the star copolymer with hydrophobic core and hydrophilic PHEMA shell verified that both the hydrophilic core and shell could host the hydrophilic guests, but the amidated HPEI core was more effective than the PHEMA shell.

关键词： Atom transfer radical polymerization Hyperbranched Polyethylenimine Poly(2-hydroxyethyl methacrylate) Star polymers.