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A FLEXIBLE OBJECTIVE-CONSTRAINT APPROACH AND A NEW ALGORITHM FOR CONSTRUCTING THE PARETO FRONT OF MULTIOBJECTIVE OPTIMIZATION PROBLEMS

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Acta Mathematica Scientia 2024年第2期44卷 702-720页

作者： N.HOSEINPOOR M.GHAZNAVI faculty of Mathematical sciences Shahrood University of TechnologyShahroodIran

In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems.

关键词： multiobjective optimization Pareto front scalarization objective-constraint approach proper efficient solution

Exergy Analysis of Charge and Discharge Processes of Thermal Energy Storage System with Various Phase Change Materials:A Comprehensive Comparison

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Journal of Thermal Science 2024年第2期33卷 509-521页

作者： Mojtaba TAHERI Fathollah POURFAYAZ Roghayeh HABIBI Akbar MALEKI Department of Renewable Energies and Environment Faculty of New Sciences and TechnologiesUniversity of TehranTehran***Iran faculty of Mechanical Engineering Shahrood University of TechnologyShahrood***Iran

Thermal energy storage(TES) is of great importance in solving the mismatch between energy production and consumption.In this regard,choosing type of Phase Change Materials(PCMs) which are widely used to control heat in latent thermal energy storage systems,plays a vital role as a means of TES efficiency.However,this field suffers from lack of a comprehensive investigation on the impact of various PCMs in terms of exergy.To address this issue,in this study,in addition to indicating the melting temperature and latent heat of various PCMs,the exergy destruction and exergy efficiency of each material are estimated and compared with each other.Moreover,in the present work the impact of PCMs mass and ambient temperature on the exergy efficiency is evaluated.The results proved that higher latent heat does not necessarily lead to higher exergy efficiency.Furthermore,to obtain a suitable exergy efficiency,the specific heat capacity and melting temperature of the PCMs must also be considered.According to the results,LiF-CaF_(2)(80.5%:19.5%,mass ratio) mixture led to better performance with satisfactory exergy efficiency(98.84%) and notably lower required mass compared to other PCMs.Additionally,the highest and lowest exergy destruction are belonged to GR25 and LiF-CaF_(2)(80.5:19.5) mixture,respectively.

关键词： exergy analysis phase change materials thermal energy storage exergy efficiency

Versatile strategies for adult neurogenesis:avenues to repair the injured brain

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Neural Regeneration Research 2024年第4期19卷 774-780页

作者： Junyi Zhao Siyu Liu Xianyuan Xiang Xinzhou Zhu The Brain Cognition and Brain Disease Institute(BCBDI) Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences faculty of Life and Health sciences Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions

Brain injuries due to trauma or stroke are major causes of adult death and disability.Unfortunately,few interventions are effective for post-injury repair of brain tissue.After a long debate on whether endogenous neurogenesis actually happens in the adult human brain,there is now substantial evidence to support its occurrence.Although neurogenesis is usually significantly stimulated by injury,the reparative potential of endogenous differentiation from neural stem/progenitor cells is usually insufficient.Alternatively,exogenous stem cell transplantation has shown promising results in animal models,but limitations such as poor long-term survival and inefficient neuronal differentiation make it still challenging for clinical use.Recently,a high focus was placed on glia-to-neuron conversion under single-factor regulation.Despite some inspiring results,the validity of this strategy is still controversial.In this review,we summarize historical findings and recent advances on neurogenesis strategies for neurorepair after brain injury.We also discuss their advantages and drawbacks,as to provide a comprehensive account of their potentials for further studies.

关键词： adult neurogenesis glia-to-neuron conversion ischemic stroke neurogenic niche neuroinflammation stem cell transplantation traumatic brain injury

Photoluminescence and ratiometric thermo-response of Eu2+ and Eu3+ in BaAl2B2O7:Eu2+,Eu3+ phosphor materials

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Journal of Rare Earths 2024年第7期42卷 1240-1249页

作者： Ziyao Wang Haitao Fu Xiufeng Zhan Bo Tong Guofeng Ma H.T.(Bert) Hintzen Institute of Innovative Science and technology Shenyang University College of Mechanical Engineering Shenyang University faculty of Applied sciences Delft University of Technology

A novel Eu2+-Eu3+co-activated ratiometric thermo-sensitive phosphor was developed and synthesized by solid-state reaction.The valence state of Eu,photoluminescence and thermo-sensitive performance of the phosphor prepared either in ambient air or carbothermally were investigated and discussed.The phosphor shows high sensitivity(Sa=0.0173 K-1,Sr=0.461%/K) and superior signal discriminability(Δv～10380 cm-1).The thermo-sensitive performance is subject to the dual effects of different thermoresponses by Eu2+versus Eu3+combined with energy transfer from Eu2+to Eu3+,so that the sensitivity of the phosphor in the temperature range presents a non-monotonic trend.The development of the BaAl2B2O7:Eu2+,Eu3+phosphor is not only expected to be relevant for application in the field of temperature sensing,but also of reference significance for improving the sensitivity by means of energy transfer between co-activator ions over a wider temperature range of Eu2+-Eu3+co-activated ratiometric thermo-sensitive phosphors.

关键词： Eu2+/Eu3+ Phosphor Photoluminescence Rare earths Ratiometric thermo-response

Multi-region calcium imaging in freely behaving mice with ultra-compact head-mounted fluorescence microscopes

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National Science Review 2024年第1期11卷 161-173页

作者： Feng Xue Fei Li Ke-ming Zhang Lufeng Ding Yang Wang Xingtao Zhao Fang Xu Danke Zhang Mingzhai Sun Pak-Ming Lau Qingyuan Zhu Pengcheng Zhou Guo-Qiang Bi Institute of Artiflcial Intelligence Hefei Comprehensive National Science Center Department of Precision Machinery and Precision Instruments University of Science and Technology of China Hefei National Laboratory for Physical sciences at the Microscale University of Science and Technology of China Interdisciplinary Center for Brain Information the Brain Cognition and Brain Disease Institute Shenzhen Institute of Advanced Technology Chinese Academy of Sciences faculty of Life and Health sciences Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences School of Life sciences University of Science and Technology of China Institute of Semiconductors Chinese Academy of Sciences Department of Modern Life sciences and Biotecnology Xiongan Institute of Innovation Xiongan New Area Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions Suzhou Institute for Advanced Research University of Science and Technology of China

To investigate the circuit-level neural mechanisms of behavior, simultaneous imaging of neuronal activity in multiple cortical and subcortical regions is highly desired. Miniature head-mounted microscopes offer the capability of calcium imaging in freely behaving animals. However, implanting multiple microscopes on a mouse brain remains challenging due to space constraints and the cumbersome weight of the equipment.Here, we present TINIscope, a Tightly Integrated Neuronal Imaging microscope optimized for electronic and opto-mechanical design. With its compact and lightweight design of 0.43 g, TINIscope enables unprecedented simultaneous imaging of behavior-relevant activity in up to four brain regions in mice.Proof-of-concept experiments with TINIscope recorded over 1000 neurons in four hippocampal subregions and revealed concurrent activity patterns spanning across these regions. Moreover, we explored potential multi-modal experimental designs by integrating additional modules for optogenetics, electrical stimulation or local field potential recordings. Overall, TINIscope represents a timely and indispensable tool for studying the brain-wide interregional coordination that underlies unrestrained behaviors.

关键词： miniature microscope multiple sites calcium imaging multimodal integration hippocampus

Synthesis of waterborne polyurethane-humic acid cross-linked biomass porous materials for the adsorption of methylene blue

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Chinese Journal of Chemical Engineering 2024年第3期67卷 27-38页

作者： Shanghong Ma Jianbo Qu Haitao Zhang Xiubin Cui Peng Ye Qingfei Hu Mingzhen Chao State Key Laboratory of Biobased Material and Green Papermaking Qilu University of TechnologyShandong Academy of SciencesJinan 250353China faculty of Light Industry Qilu University of TechnologyShandong Academy of SciencesJinan 250353China

A series of adsorbent materials(WPU-HAx-y)with a three-dimensional porous structure,green sustainability,and excellent performance were prepared and evaluated for the removal of methylene blue using nontoxic and environmentally friendly waterborne polyurethane as the matrix material and humic acid,a biomass material,as the functional material.The newly synthesized adsorbents were characterized by infrared spectroscopy,scanning electron microscopy,specific surface area,and thermogravimetric.The effects of contact time(0-8 h),starting concentration(10-100 mg·L^(-1)),pH(3-11),solution temperature(30-60℃),and coexisting ions(Ca2+,Na+,K+,Mg2+)on the performance were investigated.Pseudo-first-order,pseudo-second-order,elovich,and intra-particle diffusion models were used to analyze the adsorption kinetics;the Langmuir,Freundlich,Temkin,and Dubin-Radushkovich adsorption isotherms were evaluated;and the adsorption behavior of the adsorbent materials was found to be more appropriate for the pseudo-second-order model for chemical pollutant removal than the Langmuir model,which depends on monolayer adsorption.WPU-HA2-3 stood out with a maximum adsorption capacity of 813.0081 mg·g^(-1) fitted to the pseudo-second-order and 309.2832 mg·g^(-1) fitted to the Langmuir model,showing superior adsorption performance and regenerability.

关键词： Porous media Bioenergy Sustainability Waste water

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Methionine sources and genotype affect embryonic intestinal development, antioxidants, tight junctions, and growth-related gene expression in chickens

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Animal Nutrition 2024年第1期16卷 218-230页

作者： James K.Lugata Sawadi F.Ndunguru Gebrehaweria K.Reda Xénia E.Ozsváth Eszter Angyal Levente Czeglédi Gabriella Gulyás Renáta Knop János Oláh Zoltán Mészár Rita Varga Brigitta Csernus Csaba Szabó Department of Animal Nutrition and Physiology Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen faculty of Agriculture and Food sciences and Environmental Management Doctoral School of Animal Science University of Debrecen Department of Animal Husbandry Faculty of Agriculture and Food Sciences and Environmental Management University of Debrecen Department of Evolutionary Zoology and Human Biology Faculty of Science and Technology University of Debrecen Institutes for Agricultural Research and Educational Farm University of Debrecen Department of Anatomy Histology and Embryology Faculty of Medicine University of Debrecen

Methionine(Met) is an essential and first limiting amino acid in the poultry diet that plays a significant role in chicken embryonic development and growth. The present study examined the effect of in ovo injection of DL-Met and L-Met sources and genotypes on chicken embryonic-intestinal development and health. Fertilized eggs of the two genotypes, TETRA-SL layer hybrid(TSL)—commercial layer hybrid and Hungarian Partridge colored hen breed(HPC)—a native genotype, were randomly distributed into four treatments for each genotype. The treatment groups include the following: 1) control non-injected eggs(NoIn); 2) saline-injected(SaIn); 3) DL-Met injected(DLM); and 4) L-Met injected(LM). The in ovo injection was carried out on 17.5 d of embryonic development; after hatching, eight chicks per group were sacrificed, and the jejunum was extracted for analysis. The results showed that both DLM and LM groups had enhanced intestinal development as evidenced by increased villus width, villus height, and villus area(P < 0.05) compared to the control. The DLM group had significantly reduced crypt depth, glutathione(GSH) content, glutathione S-transferase 3 alpha(GST3), occludin(OCLN) gene expression and increased villus height to crypt depth ratio in the TSL genotype than the LM group(P < 0.05). The HPC genotype has overexpressed insulin-like growth factor 1(IGF1) gene, tricellulin(MD2), occludin(OCLN),superoxide dismutase 1(SOD1), and GST3 genes than the TSL genotype(P < 0.05). In conclusion, these findings showed that in ovo injection of Met enhanced intestinal development, and function, with genotypes responding differently under normal conditions. Genotypes also influenced the expression of intestinal antioxidants, tight junction, and growth-related genes.

关键词： DL-Methionine L-Methionine In ovo injection Intestinal development Poultry

Complications after pediatric percutaneous endoscopic gastrostomy: comparison of the push and pull technique

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World Journal of Pediatric Surgery 2024年第1期7卷 26-32页

作者： Mona Takalo Tarja Iber Reija Autio Topi Luoto faculty of Medicine and Health technology Tampere UniversityTampereFinland Department of Pediatric Surgery Tampere University HospitalTampereFinland faculty of Social sciences Tampere UniversityTampereFinland

Purpose Various complications are associatedwith percutaneous endoscopic gastrostomy(PEG)procedures in children.The push technique is being increasingly used,but its complications are insufficiently characterized.We aimed to assess all complications related to PEG procedures and compare the safety of the pull and push techniques.Methods Retrospective review of consecutive pediatric patients who underwent PEG between 2002 and 2020.Results In total,216 children underwent 217 PEG procedures.The push technique was used in 138(64%)cases,and the pull technique in 79(36%)cases.The median follow-up time was 6.1(0.1-18.3)years.The complication rate was high(57%)and patients experienced complications years after the procedure.Overall,51%and 67%of patients experienced complications in the push and pull groups,respectively.The rates of minor and major complications were higher in the pull group than in the push group(63%vs 48%,p=0.028;and 11%vs 6%,p=0.140,respectively).Reoperation was also more common in the pull group(17%vs 7%,p=0.020).Conclusions The overall complication rate of PEG procedures is high.Fortunately,most complications are mild and do not require reoperations.The increasing push technique appears to be safer than the traditional pull technique.Significant long-term morbidity is related to gastrostomies in children.

关键词： gastro pediatric push

Metallurgical performance evaluation of space-weathered Chang’e-5 lunar soil

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International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1241-1248页

作者： Chen Li Wenhui Ma Yang Li Kuixian Wei Center for Lunar and Planetary sciences Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093China

Space metallurgy is an interdisciplinary field that combines planetary space science and metallurgical engineering.It involves systematic and theoretical engineering technology for utilizing planetary resources in situ.However,space metallurgy on the Moon is challenging because the lunar surface has experienced space weathering due to the lack of atmosphere and magnetic field,making the mi-crostructure of lunar soil differ from that of minerals on the Earth.In this study,scanning electron microscopy and transmission electron microscopy analyses were performed on Chang’e-5 powder lunar soil samples.The microstructural characteristics of the lunar soil may drastically change its metallurgical performance.The main special structure of lunar soil minerals include the nanophase iron formed by the impact of micrometeorites,the amorphous layer caused by solar wind injection,and radiation tracks modified by high-energy particle rays inside mineral crystals.The nanophase iron presents a wide distribution,which may have a great impact on the electromagnetic prop-erties of lunar soil.Hydrogen ions injected by solar wind may promote the hydrogen reduction process.The widely distributed amorph-ous layer and impact glass can promote the melting and diffusion process of lunar soil.Therefore,although high-energy events on the lun-ar surface transform the lunar soil,they also increase the chemical activity of the lunar soil.This is a property that earth samples and tradi-tional simulated lunar soil lack.The application of space metallurgy requires comprehensive consideration of the unique physical and chemical properties of lunar soil.

关键词： space metallurgy Chang’e-5 lunar soil space weathering metallurgical performance