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Study of Factors Associated with the Practice of Vaccination against COVID-19 among Medical Science Students in Dakar (Senegal)

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Open Journal of Epidemiology 2024年第2期14卷 199-220页

作者： Chafika Ibrahim Zanguina Theresa Stella Esperance Fouckou Moko Jean Augustin Diegane Tine Department of Medicine El Hadji Ibrahima Niasse University of Dakar Dakar Senegal Department of Preventive Medicine and Public Health Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal

Introduction: Almost a year after the start of the COVID-19 pandemic, Senegal embarked on a vaccination campaign to protect its population. The objective of this study was to identify the factors influencing the COVID-19 vaccination practices within a health training university in Dakar. Methodology: This was a cross-sectional, descriptive and analytical study carried out from October 21 2021 to February 21 2022 among students at the Elhadj Ibrahima Niass private University in Dakar, Senegal. A 28-question online questionnaire was sent to all students enrolled at the university during this period. Results: Of the 576 students who responded, the average age was 22.60 years, with females predominating (57.81%). Medical students accounted for 66.14% of participants, pharmacy 22.40% and dental surgery 11.46%. Of these, 42.01% were bachelor’s students, 29.51% master’s students and 28.47% doctoral students. Vaccination coverage was 50.35%. Students who considered COVID-19 to be very dangerous were more likely to be vaccinated (OR = 5.05 [2.24-11.9]). Those with poor knowledge of vaccines were less likely to be vaccinated (OR = 0.07 [0.03-0.18]), as were those with poor knowledge of contraindications to vaccination (OR = 0.49 [0.28-0.86]). No association was found between vaccination status and socio-demographic or educational characteristics. Conclusion: In view of the importance of knowledge about COVID-19 vaccination, our results suggest that it is important to involve health students in the Ministry of Health’s awareness-raising strategies, because their support is necessary for better public awareness.

关键词： COVID-19 Vaccination Health Students Senegal

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Association between Diabetes Mellitus and Oral Health Status in Japanese Adults

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International Journal of Oral Science 2010年第2期2卷 82-89页

作者： Masayuki Ueno Susumu Takeuchi Akiko Oshiro Kayoko Shinada Satoko Ohara Yoko Kawaguchi Department of Oral Health Promotion Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Department of Comprehensive Oral Health Care Faculty of Dentistry Tokyo Medical and Dental University

Aim The objective of this study was to analyze the oral health among Japanese adults, with and without diabetes mellitus. Methodology The subjects were 518 community residents aged 20 to 91 years in Japan, who participated in the ＂Akita health and nutrition survey＂ and the ＂Akita dental disease survey＂, conducted in 2006. The surveys comprised a self-administered questionnaire, along with medical and dental examinations. Results Using the community periodontal index （CPI）, the mean numbers of sextants presenting codes 0, 1 and 2 were significantly lower in diabetics than non-diabetics among the 59 years or younger age group. Although the mean numbers of sextants with codes 0, 1 and 2 among the 60 to 69 years age group were lower, and sextants with a code X among the 59 years or younger age group were higher in diabetics than non-diabetics, no statistically significant differences were detected. The tendency of lower mean numbers of natural teeth and functional tooth units in diabetics than non-diabetics was observed, however no differences were statistically significant. Conclusion The outcome of periodontal disease seemed to be influenced by the diabetic state to some degree, but a clear association between diabetes and oral health status was not found.

关键词： diabetes mellitus periodontal disease community periodontal index functional tooth units

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Commensal Oral Candida in Asian Cohorts

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International Journal of Oral Science 2009年第1期1卷 2-5页

作者： Lakshman Samaranayake faculty of Dentistry The University of Hong KongPrince Philip Dental Hospital

Samaranayake L. Commensal Oral Candida in Asian Cohorts. International Journal of Oral Science, 1 （1）： 2-5, 2009The oral carriage rate of Candida in healthy humans ranges from 40% to 60%. However for a prolonged period, the oral candidal prevalence in humans was documented essentially using data from studies in the West as their prevalence in inhabitants in different regions of the world,including Asia was not known. Yet, recent reports from a number of studies indicate the quality, quantity and prevalence of oral yeasts differ between Asia and other regions for reason that are still unclear. This mini review on such data from Asian studies on oral carriage of Candida provides another intriguing facet of the behavior of this ubiquitous yeast.

关键词： Candida commensal oral Candida oralcandidal prevalence Asian cohorts

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MMP-9 deficiency accelerates the progress of periodontitis

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Genes & Diseases 2024年第5期11卷 117-121页

作者： Chun-Yan Wan Yixin Yin Xiaoyan Li Meng Meng Liu Graham Goldman Li-An Wu Feng Wang Dao-Shu Luo Zhuo Chen Wen-An Xu Stephen Chen Mary MacDougall Merry L.Lindsey Zhi Chen Shuo Chen Department of Endodontics The Affiliated Hospital of Qingdao UniversitySchool of StomatologyQingdao UniversityQingdaoShandong 266003China Department of Developmental Dentistry School of DentistryThe University of Texas Health Science Center at San AntonioSan AntonioTX 78229USA Oral Implantology Center Jinan Stomatological HospitalJinanShandong 250001China Department of Endodontics School and Hospital of StomatologyCheeloo College of MedicineShandong Key Laboratory of Oral Tissue RegenerationShandong Engineering Laboratory for Dental Materials and Oral Tissue RegenerationShandong UniversityJinanShandong 250012China Department of Pediatric Dentistry School of StomatologyThe Fourth Military Medical UniversityXi’anShaanxi 710032China Laboratory of Clinical Applied Anatomy Department of Human AnatomySchool of Basic Medical SciencesFujian Medical UniversityFuzhouFujian 350108China Key Laboratory for Oral Biomedical Research of Zhejiang Province Affiliated Hospital of StomatologyMedical CollegeZhejiang UniversityHangzhouZhejiang 310027China Department of Stomatology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China UBC faculty of Dentistry University of British ColumbiaVancouverBC V6T 1Z3Canada School of Graduate Studies and Research Meharry Medical College and Research BiologistResearch Service Nashville VA Medical CenterNashvilleTN 37208USA State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST) Key Laboratory for Oral Biomedicine of Ministry of Education(KLOBM)School and Hospital of StomatologyWuhan UniversityWuhanHubei 430079China

Periodontitis is a chronic inflammatory disease caused by periodontopathic bacteria that affects periodontal support tissues.1 If left untreated,it results in loss of periodontal attachment and alveolar bone *** one-half of adults in the United States older than 30 years have periodontal disease.2 Though the disease is initiated by bacterial infection,it activates host defense systems that eventually lead to the degradation of the *** periodontitis,the disease progress involves further production of pro-inflammatory mediators such as cytokines,proteolytic enzymes like matrix metalloproteinases(MMPs),and their inhibitors.

关键词： period eventually untreated

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Growing importance of urogenital candidiasis in individuals with diabetes:A narrative review

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World Journal of Diabetes 2022年第10期13卷 809-821页

作者： Jasminka Talapko Tomislav Meštrović IvanaŠkrlec Laboratory for Microbiology Faculty of Dental Medicine and HealthJosip Juraj Strossmayer University of OsijekOsijek 31000Croatia University North University Centre VaraždinVaraždin 42000Croatia Institute for Health Metrics and Evaluation Department for Health Metrics SciencesUniversity of Washington School of MedicineSeattleWashington 98195United States Department of Biophysics Biologyand ChemistryFaculty of Dental Medicine and HealthJ.J.Strossmayer University of OsijekOsijek 31000Croatia

Both diabetes and fungal infections contribute significantly to the global disease burden,with increasing trends seen in most developed and developing countries during recent *** is reflected in urogenital infections caused by Candida species that are becoming ever more pervasive in diabetic patients,particularly those that present with unsatisfactory glycemic *** addition,a relatively new group of anti-hyperglycemic drugs,known as sodium glucose cotransporter 2 inhibitors,has been linked with an increased risk for colonization of the urogenital region with Candida spp.,which can subsequently lead to an infectious *** this review paper,we have highlighted notable virulence factors of Candida species(with an emphasis on Candida albicans)and shown how the interplay of many pathophysiological factors can give rise to vulvovaginal candidiasis,potentially complicated with recurrences and dire pregnancy *** have also addressed an increased risk of candiduria and urinary tract infections caused by species of Candida in females and males with diabetes,further highlighting possible complications such as emphysematous cystitis as well as the risk for the development of balanitis and balanoposthitis in(primarily uncircumcised)*** a steadily increasing global burden of diabetes,urogenital mycotic infections will undoubtedly become more prevalent in the future;hence,there is a need for an evidence-based approach from both clinical and public health perspectives.

关键词： Balanitis Balanoposthitis Candida Candidiasis Diabetes Pregnancy Urogenital infections Vulvovaginitis

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Bioactive 3D-printed chitosan-based scaffolds for personalized craniofacial bone tissue engineering

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再生工程(英文) 2023年第1期4卷 1-11页

作者： Satar Yousefiasl Esmaeel Sharifi Erfan Salahinejad Pooyan Makvandi Soussan Irani School of Dentistry Hamadan University of Medical SciencesHamadan ***Iran Department of Tissue Engineering and Biomaterials School of Advanced Medical Sciences and TechnologiesHamadan University of Medical SciencesHamadanIran faculty of Materials Science and Engineering K.N.Toosi University of TechnologyTehranIran Centre for Materials Interfaces Istituto Italiano di Tecnologiaviale Rinaldo Piaggio 34PontederaPisa 56025Italy dental Research Centre Oral Pathology DepartmentDental FacultyHamadan University of Medical SciencesHamadanIran

Regeneration of craniofacial bone defects is a key issue in the bone regeneration ***,novel treatment strategies,such as tissue engineering using porous scaffolds,have been *** ideal tissue-engineered scaffold for bone tissue regeneration should possess pores to facilitate nutrients transmission and support repar-ative tissue ingrowth,bioactivity for osteoconduction and osseointegration,and biocompatibility to improve cell attachment,proliferation,and extracellular matrix *** the present study,we manufactured chitosan-based hydrogels substituted with alginate with optimized properties by extrusion-based three-dimensional(3D)printing.3D printing of the scaffolds enables the designing and developing of complex architectures for cranio-facial reconstruction using computer-aided design(CAD).Different ratios(2.5,5,and 10%)of hydroxyapatite were added to the hydrogel,printed,and subsequently lyophilized to augment the physical and biological char-acteristics of the *** incorporation into the chitosan-based scaffolds increased the porosity and pore size of the printed *** addition,the presence of hydroxyapatite amplified apatite formation and decreased the size of formed apatite *** the scaffold samples showed biocompatible properties and did not have toxicity toward rat bone marrow mesenchymal stem ***,the scaffolds containing 5%w/w hydroxyapatite exhibited significant growth in cell viability compared to the ***,it is concluded that chitosan-based scaffolds adorned with hydroxyapatite are considerable for regenerating craniofacial bone defects.

关键词： Bioactivity CAD/CAM Maxillofacial reconstruction Pore Stem cells

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Gingival unit transfer using in the Miller Ⅲ recession defect treatment

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World Journal of Clinical Cases 2015年第2期3卷 199-203页

作者： Selin Y?ld?r?m Bahar Kuru Department of Periodontology Dental FacultyMarmara University

The most significant factor for the success in soft tissue grafts is the synergistic relation between vascular configuration and involved tissues. In the soft tissue graft procedures, site specific donor tissue is assumed to have improved potential for function and aesthetic survive at recipient sites. On a clinical level, using site specific gingival unit graft that placed on traditionally prepared recipient site, results in predictable root coverage. In this case report the clinical effectiveness of gingival unit transfer(GUT) technique performed on Miller Ⅲ recession was presented and a similar recession case treated with free gingival graft(FGG) technique for comparison. Probing depth, recession depth, keratinized tissue width and clinical attachment level clinical parameters were measured at baseline and postoperative 8 mo. Percentage of defect coverage was evaluated at postoperative 8 mo. Creeping attachment was assessed at postoperative 1, 3, 6 and 8 mo. The GUT revealed better defect coverage and creeping attachment results than the FGG in the treatment of Miller Ⅲ defects.

关键词： Autografting Gingiva Gingival recession Tooth root Transplants

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Titanium membrane layered between fluvastatin-loaded poly(lactic-co-glycolic)acid for guided bone regeneration

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Regenerative Biomaterials 2022年第1期9卷 816-826页

作者： Akihiro Furuhashi Yunia Dwi Rakhmatia Yasunori Ayukawa Kiyoshi Koyano Section of Implant and Rehabilitative Dentistry Division of Oral RehabilitationFaculty of Dental ScienceKyushu UniversityHigashiFukuoka-ku 812-8582Japan Division of Advanced dental Devices and Therapeutics Faculty of Dental ScienceKyushu UniversityHigashiFukuoka-ku 812-8582Japan Department of Prosthodontic Faculty of DentistryPadjadjaran UniversityKota BandungJawa Barat 40132Indonesia

The aimof this study was to investigate titaniummembranes(TMs)layered between poly(lactic-co-glycolic acid)(PLGA)containing fluvastatin(FS)for use in guided bone *** consisting of PLGA,FS-containing PLGA(PLGA–FS),TM layered between PLGA(TM–PLGA)and TM layered between FS-containing PLGA(TM–PLGA–FS)were prepared,and their mechanical and chemical properties were *** TM groups showed statistically significant differences,in terms of tensile strength and elastic modulus,when compared to the PLGA *** release of FS was demonstrated to be higher in the TM–PLGA–FS group than the PLGA–FS group after Day *** effect of membrane implantation on the calvaria of Wistar rats was measured using micro-computed tomography(micro-CT)and morphometrical analyses,as well as histological *** 4weeks,the TM–PLGA–FS and TM–PLGA groups were found to have lower bone mineral density but higher bone formation,when compared to the control and PLGA *** 8weeks,the use of TM–PLGA–FS membranes significantly enhanced bone formation in the calvaria model,compared to the other *** results suggest that a TM layered between PLGA containing FS potentially enhances bone formation,thus showing good potential as a GBR membrane.

关键词： titanium mesh PLGA statin guided bone regeneration(GBR)

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Biodegradable magnesium barrier membrane used for guided bone regeneration in dental surgery

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Bioactive Materials 2022年第8期7卷 152-168页

作者： Patrick Rider Zeljka Peric Kacarevic Akiva Elad Drazen Tadic Daniel Rothamel Gerrit Sauer Fabien Bornert Peter Windisch David Botond Hangyasi Balint Molnar Emely Bortel Bernhard Hesse Frank Witte Department of Prosthodontics Geriatric Dentistry and Craniomandibular DisordersCharite-Universitatsmedizin BerlinAßmannshauser Straße 4-614197BerlinGermany Botiss Biomaterials AG Ullsteinstrasse 10812109BerlinGermany Department of Anatomy Histology EmbryologyPathology Anatomy and Pathology HistologyFaculty of Dental Medicine and HealthUniversity of OsijekOsijek31000Croatia CMF surgery Johannes BLA HospitalMonchengladbachGermany dental Clinic University of StrasbourgFrance Department of Periodontology Semmelweis UniversityBudapestHungary Xploraytion GmbH Bismarkstrasse 11BerlinGermany Biotrics Bioimplants AG Ullsteinstrasse 10812109BerlinGermany

Barrier membranes are commonly used as part of the dental surgical technique guided bone regeneration(GBR)and are often made of resorbable collagen or non-resorbable materials such as *** collagen membranes do not provide sufficient mechanical protection of the covered bone defect,titanium reinforced membranes and non-resorbable membranes need to be removed in a second ***,biodegradable GBR membranes made of pure magnesium might be an *** this study a biodegradable pure magnesium(99.95%)membrane has been proven to have all of the necessary requirements for an optimal regenerative outcome from both a mechanical and biological *** implantation,the magnesium membrane separates the regenerating bone from the overlying,faster proliferating soft *** the initial healing period,the membrane maintained a barrier function and space provision,whilst retaining the positioning of the bone graft material within the defect *** the magnesium metal corroded,it formed a salty corrosion layer and local gas cavities,both of which extended the functional lifespan of the membrane barrier *** the resorption of the magnesium metal and magnesium salts,it was observed that the membrane became surrounded and then replaced by new *** the membrane had completely resorbed,only healthy tissue *** in vivo performance study demonstrated that the magnesium membrane has a comparable healing response and tissue regeneration to that of a resorbable collagen ***,the magnesium membrane demonstrated all of the ideal qualities for a barrier membrane used in GBR treatment.

关键词： Magnesium Biodegradable Implant GBR Bone healing Soft tissue healing

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Advances in orthodontic clear aligner materials

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Bioactive Materials 2023年第4期22卷 384-403页

作者： Yashodhan M.Bichu Abdulraheem Alwafi Xiaomo Liu James Andrews Bjorn Ludwig Aditi Y.Bichu Bingshuang Zou Private Practice Abu DhabiUnited Arab Emirates Department of Oral Health Science Faculty of DentistryUniversity of British ColumbiaVancouverCanada faculty of Dentistry Department of Dental Public HealthKing Abdulaziz UniversityJeddahSaudi Arabia Department of Orthodontics Peking University School and Hospital of StomatologyBeijingChina Private Practice PerthAustralia Department of Orthodontics University of HomburgSaarGermany

Rapid technological improvements in biomaterials,computer-aided design(CAD)and manufacturing(CAM)have endorsed clear aligner therapy(CAT)as a mainstay of orthodontic treatment,and the materials employed for aligner fabrication play an all-important role in determining the clinical performance of clear *** narrative review has attempted to comprehensively encompass the entire gamut of materials currently used for the fabrication of clear aligners and elucidate their characteristics that are crucial in determining their performance in an oral *** developments and current protocols in aligner fabrication,features of contemporary bioactive materials,and emerging trends related to CAT are *** in aligner material chemistry and engineering possess the potential to bring about radical transformations in the therapeutic applications of CAT;in the absence of which,clear aligners would continue to underperform clinically,due to their inherent biomechanical ***,while innovations in aligner materials such as shape memory polymers,direct three-dimensional(3D)printed clear aligners and bioactive materials combined with clear aligner materials are essential to further advance the applications of CAT;increased awareness of environmental responsibilities among aligner manufacturers,aligner prescribing clinicians and aligner users is essential for better alignment of our climate change goals towards a sustainable planet.

关键词： Clear aligners Bioactive materials Shape memory polymers Direct 3D printing Environment Review

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