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Effect of a Diet Rich in Interesterified, Non-Interesterified and Trans Fats on Biochemical Parameters and Oxidative Status of Balb-c Mice

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Food and Nutrition Sciences 2020年第11期11卷 1032-1052页

作者： Elinete Eliete de Lima Luiza S. E. P. W. Castro Valdelúcia Maria A. de S. Grinevicius Josiane Hilbig Nádia S. R. S. Mota Rodrigo C. Zeferino Roberta C. da Silva Iván Jachmanián Edson Luiz da Silva Rozangela C. Pedrosa Jane Mara Block Laboratory of Fats and Oils Department of Food Science and Technology Federal University of Santa Catarina Florianópolis SC Brazil Campus Florianópolis Continente Federal Institute of Education Science and Technology of Santa Catarina Florianópolis-SC Brazil Laboratory of Experimental Biochemistry Department of Biochemistry Federal University of Santa Catarina Florianópolis SC Brazil Faculty of Pharmaceutical Sciences University of S&#227 o Paulo S&#227 o Paulo-SP Brazil Laboratory of Lipid Research Department of Family and Consumer Sciences College of Agriculture and Environmental Sciences North Carolina A & T State University NC USA department of Food Science and Technology Facultad de Química Universidad de la República Montevideo Uruguay Laboratory of Lipids Department of Clinical Analysis Federal University of Santa Catarina Florianópolis-SC Brazil

The aim of this study was to investigate the effects of different modified fats on the body weight, biochemical profile, and biomarkers of hepatic oxidative status in Balb-c mice. The animals were divided into four groups and fed for 75 days with a normolipidic (Control Group, CG) or hiperlipidic diets (40% kcal) containing a commercial interesterified fat (IFG) rich in palmitic acid (39%);a blend of non-interesterified fat (NIFG), with 2-fold less saturated fatty acids at the sn-2 position of triacylglycerols;or a partially hydrogenated vegetable oil (PHFG), source of trans fatty acid (20%) and of linolenic acid (6%). The mice of the IFG and NIFG presented similar results in all evaluated parameters. The serum biochemical profile and hepatic oxidative stress markers in mice of the PHFG were similar to CG, except for total cholesterol (TC) which was significantly higher (p e PHFG. The mice feed with interesterified fat (IFG) showed serum TC (p < 0.01), non-HDL-C (p < 0.05), gluco

关键词： Interesterified Fat Trans Fat Palmitic Acid Cholesterol Oxidative Stress

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β-淀粉样蛋白损害星形胶质细胞在阿尔茨海默病中对营养不良突触的吞噬作用

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神经损伤与功能重建 2021年第5期16卷 F0003-F0003页

作者： Maria V Sanchez-Mico Sebastian Jimenez Angela Gomez-Arboledas Clara Muñoz-Castro Carmen Romero-Molina Victoria Navarro Elisabeth Sanchez-Mejias Cristina Nuñez-Diaz Raquel Sanchez-Varo Elena Galea JoséC Davila Marisa Vizuete Antonia Gutierrez Javier Vitorica 杜一星(编译) Dpto.bioquimica y Biologia Molecular Facultad de FarmaciaUniversidad de SevillaSevillaSpain Instituto de Biomedicina de Sevilla(IBiS)-Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla SevillaSpain Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas(CIBERNED) MadridSpain department of Neurology Massachusetts General Hospital and Harvard Medical SchoolCharlestownMassachusettsUSA Dpto.Biologia Celular Genetica y FisiologiaInstituto de Investigación Biomedica de Malaga-IBIMAFacultad de CienciasUniversidad de MalagaMalagaSpain Institut de Neurociències and departament de bioquímica i Biologia Molecular Unitat de Bioquímica de MedicinaUniversitat Autònoma de BarcelonaBarcelonaSpain ICREA BarcelonaSpain. 不详

摘要在阿尔茨海默病(AD)中,在β-淀粉样蛋白斑块周围发现了反应性星形胶质细胞和营养不良的神经突(异常的突触前元件)。笔者的前期研究已经表明,反应性星形胶质细胞会包裹、吞噬和降解APP小鼠以及AD患者海马中营养不良的突触,但仅波及不... 详细信息

摘要在阿尔茨海默病(AD)中,在β-淀粉样蛋白斑块周围发现了反应性星形胶质细胞和营养不良的神经突(异常的突触前元件)。笔者的前期研究已经表明,反应性星形胶质细胞会包裹、吞噬和降解APP小鼠以及AD患者海马中营养不良的突触,但仅波及不到7%的营养不良神经突,这表明星形胶质细胞在AD中的吞噬能力降低。本研究旨在通过分析原代星形胶质细胞培养物对分离突触(突触神经小体,SNs)吞噬和降解的能力来深入了解其潜在机制。SNs分别来自APP(包含营养不良性突触和β淀粉样肽)小鼠、Tau(包含AT8-和AT100-阳性磷酸化Tau)小鼠以及WT(对照)小鼠。我们发现与SNs-WT相比,星形胶质细胞的吞噬和降解能力在SNs-APP大大降低,但在AT8/AT100阳性的SNs-Tau却没有。在12月大的APP小鼠的海马中证实了星形胶质细胞吞噬能力的降低,因为只有(1.60±3.81)%的斑块状星形胶质细胞具有吞噬结构。

关键词：老年痴呆 β-淀粉样蛋白星形胶质细胞营养不良性突触小胶质细胞病理吞噬作用

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ANTI-TRYPANOSOMA CRUZI ACTIVITY OF 20 MEDICINAL PLANTS USED IN NORTH EAST MEXICO

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 101-101页

作者： Ramiro Quintanilla-Licea Isvar Kavim Angeles Hernández Zinnia Judith Molina-Garza Lucio GalavizSilva Universidad Autónoma de Nuevo León UANL Facultad de Ciencias Biológicas Ave.Universidad S/N Cd.Universitaria

Chagas disease is caused by the protozoan parasite Trypanosoma *** disease is also known as American trypanosomiasis and approximately 7-8 million people are currently infected(WHO,*** has been used for over 40 years to treat Chagas disease,however,this drug is only effective during the acute phase of infection,and certain protozoan strains have developed resistance

关键词： ANTI-TRYPANOSOMA CRUZI ACTIVITY OF 20 MEDICINAL PLANTS USED IN NORTH EAST MEXICO

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development of a Construction Material for Indoor and Outdoor, Metakaolinite-Based Geopolymer, with Environmental Properties

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材料科学与工程（中英文A版） 2019年第4期9卷 131-142页

作者： M.Mondragón-Figueroa Héctor.R.Guzmán-Carrillo MiguelÁngel Rico JoséLuis.Reyez-Araiza Jorge.Pineda-Piñón Edgar J.López-Naranjo María C.Columba-Palomares Jóse.M.López-Romero Josè.Ramón Gasca-Tirado Alejandro.Manzano-Ramírez CINVESTAV-Querétaro Libramiento Norponiente#2000Fraccionamiento Real de JuriquillaQuerétaro 76230Qro.México facultad de Química Universidad Autónoma de Querétaro centro de estudios Académicos sobre contaminación AmbientalQuerétaro 76010Qro.México DIPFI Facultad de IngenieríaUniversidad Autónoma de QuerétaroC.U.Cerro de las CampanasCentroQuerétaro 76010Qro.México Instituto Politécnico Nacional Centro de Investigación en Ciencia Aplicada y Tecnología AvanzadaUnidad QuerétaroCerro Blanco No.141Colinas del CimatarioQuerétaro76090Qro.México DIP-CUCEI Universidad de GuadalajaraJoséGuadalupe Zuno#48Los BelenesZapopan 45100Jal.México facultad de Farmacia Universidad Autónoma del Estado de MorelosAv.Universidad#1001Cuernavaca 62209Mor.México departamento de Ingeniería Universidad de GuanajuatoGuanajuato 36000México

Environmental problems that came from the human activity have many facets,since pollution of the atmosphere arises from vehicles,industrial emissions while pollution of water could be from organic compounds,pesticides *** can cause serious health effects,such as respiratory diseases,including asthma and lung ***,in the present work,a kinetic study on the effective adsorption and photo degradation of methylene blue(MB)dye,under ultraviolet A(UVA)irradiation of an alkali activated inorganic polymer(geopolymer)with homogeneously dispersed titanium dioxide(TiO2)micro-particles is *** addition,antimicrobial testing of the alkali activated TiO2 material was performed showing a bacteriostatic effect.

关键词： Heterogeneous photocatalysis semiconductor alkali activated bacteriostatic effect

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Notes for genera:Ascomycota

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Fungal Diversity 2017年第5期86卷 1-594页

作者： Nalin N.Wijayawardene Kevin D.Hyde Kunhiraman C.Rajeshkumar David L.Hawksworth Hugo Madrid Paul M.Kirk Uwe Braun Rajshree V.Singh Pedro W.Crous Martin Kukwa Robert Lücking Cletus P.Kurtzman Andrey Yurkov Danny Haelewaters Andre´Aptroot H.Thorsten Lumbsch Einar Timdal Damien Ertz Javier Etayo Alan J.L.Phillips Johannes Z.Groenewald Moslem Papizadeh Laura Selbmann Monika C.Dayarathne Gothamie Weerakoon E.B.Gareth Jones Satinee Suetrong Qing Tian Rafael F.Castanda-Ruiz Ali H.Bahkali Ka-Lai Pang Kazuaki Tanaka Dong Qin Dai Jariya Sakayaroj Martina Hujslová Lorenzo Lombard Belle D.Shenoy Ave Suija Sajeewa S.N.Maharachchikumbura Kasun M.Thambugala Dhanushka N.Wanasinghe Bharati O.Sharma Subhash Gaikwad Gargee Pandit Laura Zucconi Silvano Onofri Eleonora Egidi Huzefa A.Raja Rampai Kodsueb Marcela E.S.Caceres Sergio Perez-Ortega Patrícia O.Fiuza Josiane Santana Monteiro Larissa N.Vasilyeva Roger G.Shivas Maria Prieto Mats Wedin Ibai Olariaga Adebola Azeez Lateef Yamini Agrawal Seyed Abolhassan Shahzadeh Fazeli Mohammad Ali Amoozegar Guo Zhu Zhao Walter P.Pfliegler Gunjan Sharma Magdalena Oset Mohamed A.Abdel-Wahab Susumu Takamatsu Konstanze Bensch Nimali Indeewari de Silva Andréde Kesel Anuruddha Karunarathna Saranyaphat Boonmee Donald H.Pfister Yong-Zhong Lu Zong-Long Luo Nattawut Boonyuen Dinushani A.Daranagama Indunil C.Senanayake Subashini C.Jayasiri Milan C.Samarakoon Xiang-Yu Zeng Mingkwan Doilom Luis Quijada Sillma Rampadarath Gabriela Heredia Asha J.Dissanayake Ruvishika S.Jayawardana Rekhani H.Perera Li Zhou Tang Chayanard Phukhamsakda Margarita Hernańdez-Restrepo Xiaoya Ma Saowaluck Tibpromma Luis F.P.Gusmao Darshani Weerahewa Samantha C.Karunarathna Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology(Fungi)GroupAgharkar Research InstitutePuneMaharashtra 411004India Royal Botanic Gardens KewRichmondSurrey TW93DSUK department of Life Sciences The Natural History MuseumCromwell RoadLondon SW75BDUK Jilin Agricultural University Changchun 130118JilinPeople’s Republic of China Centro de Geno´mica y Bioinforma´tica Facultad de CienciasUniversidad Mayor de ChileCamino La Pira´mide 5750HuechurabaSantiagoChile Martin-Luther-Universita¨t Institut fu¨r BiologieBereich Geobotanik und Botanischer GartenHerbariumNeuwerk 2106099 Halle(Saale)Germany Westerdijk Fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands department of Plant Taxonomy and Nature Conservation Faculty of BiologyUniversity of Gdan´skWita Stwosza 5980-308 Gdan´skPoland Botanic Garden and Botanical Museum Königin-Luise-Str.6-814195 BerlinGermany Mycotoxin Prevention and Applied Microbiology Research Unit National Center for Agricultural Utilization ResearchAgricultural Research ServiceU.S.Department of AgriculturePeoriaIL 61604USA Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures Inhoffenstraße 7B38124 BrunswickGermany Farlow Reference Library and Herbarium of Cryptogamic Botany Harvard University22 Divinity AvenueCambridgeMA 02138USA department of Organismic and Evolutionary Biology Harvard University22 Divinity AvenueCambridgeMA 02138USA ABL Herbarium G.v.d.Veenstraat 1073762 XK SoestThe Netherlands Science&Education The Field Museum1400

Knowledge of the relationships and thus the classification of fungi,has developed rapidly with increasingly widespread use of molecular techniques,over the past 10–15 years,and continues to *** genera have been found to be polyphyletic,and their generic concepts have subsequently been *** names have thus been introduced for species which are phylogenetically distinct from the type species of particular *** ending of the separate naming of morphs of the same species in 2011,has also caused changes in fungal generic *** order to facilitate access to all important changes,it was desirable to compile these in a single *** present article provides a list of generic names of Ascomycota(approximately 6500 accepted names published to the end of 2016),including those which are *** and summaries of the changes since the last edition of‘Ainsworth&Bisby’s Dictionary of the Fungi’in 2008 are *** notes include the number of accepted species,classification,type species(with location of the type material),culture availability,life-styles,distribution,and selected publications that have appeared since *** work is intended to provide the foundation for updating the ascomycete component of the"Without prejudice list of generic names of Fungi"published in 2013,which will be developed into a list of protected generic *** will be subjected to the XIXth International Botanical Congress in Shenzhen in July 2017 agreeing to a modification in the rules relating to protected lists,and scrutiny by procedures determined by the Nomenclature Committee for Fungi(NCF).The previously invalidly published generic names Barriopsis,Collophora(as Collophorina),Cryomyces,dematiopleospora,Heterospora(as Heterosporicola),Lithophila,Palmomyces(as Palmaria)and Saxomyces are validated,as are two previously invalid family names,Bartaliniaceae and *** species of Lalaria,which were invalidly published are trans

关键词： Article 59 Classification One name Pleomorphic fungi Taxonomy

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Human genetic and immunological determinants of critical COVID-19 pneumonia

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四川生理科学杂志 2021年第11期43卷 1947-1947页

作者： Qian Zhang St Giles Laboratory of Human Genetics of Infectious Diseases Rockefeller Branch The Rockefeller University New York NY USA Laboratory of Human Genetics of Infectious Diseases Necker Branch INSERM U1163 Necker Hospital for Sick Children Paris France University of Paris Imagine Institute Paris France Howard Hughes Medical Institute Paris France The Rockefeller University & Howard Hughes Medical Institute New York NY USA Necker Hospital for Sick Children & INSERM Paris France department of Pediatrics Necker Hospital for Sick Children Paris France Cemil Taşcıoglu City Hospital Istanbul Turkey Laboratory of Human Genetics of Infectious Diseases Necker Branch INSERM U1163 Necker Hospital for Sick Children Paris France Imagine Institute University of Paris Paris France Al Jalila Children’s Hospital Dubai United Arab Emirates San Raffaele Telethon Institute for Gene Therapy IRCCS Ospedale San Raffaele and Vita Salute San Raffaele University Milan Italy Hospices Civils de Lyon Lyon France Helix San Mateo CA USA department of Intensive Care Medicine Critical Care Center CHU Lille Lille France Univ. Lille CNRS Inserm CHU Lille Institut Pasteur de Lille U1019-UMR9017-CIIL-Centre d’Infection et d’Immunité deLille Lille France Shupyk National Medical Academy for Postgraduate Education Kiev Ukraine department of Medical Microbiology University Medical Center Utrecht Utrecht The Netherlands Sidra Medicine Doha Qatar Primary Immunodeficiencies Group Department of Microbiology and Parasitology School of Medicine University of Antioquia Medellín Colombia School of Microbiology University of Antioquia Medellín Colombia IIBB-CSIC IDIBAPS Barcelona Spain department of Immunology Second Faculty of Medicine Charles University University Hospital in Motol Prague Czech Republic department of Immunology Dmitry Rogachev National Medical Research Center of Pediatric Hematology Oncology and Immunology Moscow Russia Pulmonology department Cliniques Universitaire

SARS-CoV-2 infection is benign in most individuals but,in-10%of cases,it triggers hypoxemic COVID-19 pneumonia,which becomes critical in-3%of *** ensuing risk of death(-1%)doubles every five years from childhood onward and is-1.5 times greater in men than in *** are the molecular and cellular determinants of critical COVID-19 pneumonia?Inborn errors of type I IFNs,including autosomal TLR3 and X-linked TLR7 deficiencies,are found in-1-5%of patients with critical pneumonia under 60 years old.

关键词： pneumonia critical cases

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