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Acute effect of foot strike patterns on in vivo tibiotalar and subtalar joint kinematics during barefoot running

Journal of Sport and health Science 2024年第1期13卷 108-117页

作者： Dongqiang Ye Lu Li Shen Zhang Songlin Xiao Xiaole Sun Shaobai Wang Weijie Fu Key laboratory of exercise and health Sciences of Ministry of Education Shanghai University of SportShanghai 200438China Shanghai Frontiers Science Research Base of exercise and Metabolic health Shanghai University of SportShanghai 200438China

Background:Foot kinematics,such as excessive eversion and malalignment of the hindfoot,are believed to be associated with running-related *** maj ority of studies to date show that different foot strike patterns influence these specific foot and ankle ***,technical deficiencies in traditional motion capture approaches limit knowledge of in vivo joint kinematics with respect to rearfoot and forefoot strike patterns(RFS and FFS,respectively).This study uses a high-speed dual fluoroscopic imaging system(DFIS)to determine the effects of different foot strike patterns on 3D in vivo tibiotalar and subtalar joints ***:Fifteen healthy male recreational runners underwent foot computed tomography scanning for the construction of 3-dimensional models.A high-speed DFIS(100 Hz)was used to collect 6 degrees of freedom kinematics for participants’tibiotalar and subtalar joints when they adopted RFS and FFS in barefoot ***:Compared with RFS,FFS exhibited greater internal rotation at 0%-20%of the stance phase in the tibiotalar *** peak internal rotation angle of the tibiotalar joint under FFS was greater than under RFS(p<0.001,Cohen’s d=0.92).RFS showed more dorsiflexion at 0%-20%of the stance phase in the tibiotalar joint than *** also presented a larger anterior translation(p<0.001,Cohen’s d=1.28)in the subtalar joint at i nitial contact than ***:Running with acute barefoot FFS increases the internal rotation of the tibiotalar joint in the early *** use of high-speed DFIS to quantify the movement of the tibiotalar and subtalar joint was critical to revealing the effects of RF S and FFS during running.

关键词： Foot strike patterns High-speed dual fluoroscopic imaging system In vivo kinematics Running

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Resveratrol combats chronic diseases through enhancing mitochondrial quality

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Food Science and Human Wellness 2024年第2期13卷 597-610页

作者： Weichu Tao Hu Zhang Xia Jiang Ning Chen Tianjiu Research and Development Center for exercise Nutrition and Foods Hubei Key Laboratory of Exercise Training and MonitoringCollege of Sports MedicineWuhan Sports UniversityWuhan 430079China The University Hospital of Wuhan Sports University Wuhan 430079China

Resveratrol(RSV),as a functional food component extracted from natural plants,has been widely studied and recognized in preventing and treating various diseases,with major mechanisms including executing anti-inflammation and anti-oxidation functions,and improving mitochondrial *** diseases as non-communicable diseases are mainly caused by multiple factors,such as physiological decline and dysfunction in the body,and have become a significant challenge on public health *** is worth noting that chronic diseases such as Alzheimer's disease(AD),Parkinson's disease(PD),muscle atrophy,cardiovascular disease,obesity,and cancer are accompanied by abnormal mitochondrial ***,targeted regulation of mitochondria may be a meaningful way to prevent and treat chronic *** evidence has confirmed that RSV is actively involved in regulating mitochondria,and it has become an essential consideration to prevent and treat chronic diseases through targeting mitochondria and improving corresponding *** this article,current studies on RSV to optimize mitochondrial quality for preventing and alleviating chronic disease are systematically summarized,which can provide a theoretical reference for the development of functional foods or drugs to combat chronic diseases.

关键词： Resveratrol Functional food Mitochondrial quality Chronic disease Anti-inflammation Anti-oxidation

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exercise-induced microbial changes in preventing type 2 diabetes

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Science China(Life Sciences) 2024年第5期67卷 892-899页

作者： Ting Yao Hui Wang Kaiqing Lin Ruwen Wang Shanshan Guo Peijie Chen Hao Wu Tiemin Liu Ru Wang School of exercise and health Shanghai Frontiers Science Research Base of Exercise and Metabolic HealthShanghai University of SportShanghai 200438China Department of Physiology and Pathophysiology School of Basic Medical SciencesXi’an Jiaotong University School of MedicineXi’an 710061China Shanghai Key laboratory of Metabolic Remodeling and health Institute of Metabolism&Integrative BiologyFudan UniversityShanghai 200433China State Key laboratory of Genetic Engineering Human Phenome InstituteFudan Microbiome Centerand Department of Bariatric and Metabolic SurgeryHuashan HospitalFudan UniversityShanghai 201203China State Key laboratory of Genetic Engineering Department of Endocrinology and MetabolismHuman Phenome Instituteand School of Life SciencesZhongshan HospitalFudan UniversityShanghai 200032China

The metabolic benefits associated with long-term physical activity are well appreciated and growing evidence suggests that it involves the gut *** we re-evaluated the link between exercise-induced microbial changes and those associated with prediabetes and *** found that the relative abundances of substantial amounts of diabetes-associated metagenomic species associated negatively with physical fitness in a Chinese athlete students *** additionally showed that those microbial changes correlated more with handgrip strength,a simple but valuable biomarker suggestive of the diabetes states,than maximum oxygen intake,one of the key surrogates for endurance ***,the causal relationships among exercise,risks for diabetes,and gut microbiota were explored based on mediation *** propose that the protective roles of exercise against type 2 diabetes are mediated,at least partly,by the gut microbiota.

关键词： gut microbiota body fat diabetes handgrip maximum oxygen intake

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A systematic scoping review of study methodology for randomized controlled trials investigating probiotics in athletic and physically active populations

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Journal of Sport and health Science 2024年第1期13卷 61-71页

作者： Alex E.Mohr David B.Pyne Geovana Silva Fogaça Leite Deborah Akins Jamie Pugh College of health Solutions Arizona State UniversityPhoenixAZ 85004USA Research Institute for Sport and exercise University of CanberraCanberraACT 2617Australia laboratory of Functional Fermented Food Faculty of Pharmaceutical SciencesUniversity of São PauloSão Paulo 05508-030Brazil Research Institute for Sport and exercise Sciences Liverpool John Moores UniversityLiverpool L33AFUK

Background:The purported ergogenic and health effects of probiotics have been a topic of great intrigue among researchers,practitioners,and the lay public *** has also been an increased research focus within the realm of sports science and exercise medicine on the athletic gut ***,compared to other ergogenic aids and dietary supplements,probiotics present unique study *** objectives of this systematic scoping review were to identify and characterize study methodologies of randomized controlled trials investigating supplementation with probiotics in athletes and physically active ***:Four databases(MEDLINE,CINAHL,Cochrane CENTRAL,and Cochrane Database of Systematic Reviews)were searched for randomized controlled studies involving healthy athletes or physically active *** intervention with probiotics and inclusion of a control and/or placebo group were *** peer-reviewed articles in English were considered,and there were no date *** were extracted and presented in tabular form to detail study protocols,characteristics,and *** in randomized controlled trials was determined with the RoB 2.0 ***:A total of 45 studies were included in the review,with 35 using a parallel group design and 10 using a cross-over *** half the studies used a single probiotic and the other half a multi-strain *** probiotic dose ranged from 2×10^(8)to 1×10^(11)colony forming units daily,and the length of intervention was between 7 and 150 *** than half the studies directly assessed gastrointestinal symptoms,gut permeability,or the gut *** sex ratio of participants was heavily weighted toward males,and only 3 studies exclusively investigated ***-level adverse events were reported in only 2 studies,although the methodology of reporting varied *** risk of bias was generally low,although details on randomization were lacking in some s

关键词： exercise Experimental methodology Gastrointestinal symptoms Gut microbiota Probiotic supplementation

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exercise-induced adaptation of neurons in the vertebrate locomotor system

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Journal of Sport and health Science 2024年第2期13卷 160-171页

作者： Yue Dai Yi Cheng Renkai Ge Ke Chen Liming Yang Key Lab of Adolescent health Assessment and exercise Intervention of Ministry of Education College of Physical Education and Health CareEast China Normal UniversityShanghai 200241China Shanghai Key laboratory of Multidimensional Information Processing School of Communication and Electronic EngineeringEast China Normal UniversityShanghai 200241China School of Physical Education and health Care East China Jiaotong UniversityNanchang 330013China Key laboratory of High Confidence Software Technologies of Ministry of Education School of Computer SciencePeking UniversityBeijing 100871China

Vertebrate neurons are highly dynamic cells that undergo several alterations in their functioning and physiologies in adaptation to various external *** particular,how these neurons respond to physical exercise has long been an area of active *** of the vertebrate locomotor system’s adaptability suggest multiple mechanisms are involved in the regulation of neuronal activity and properties during *** this brief review,we highlight recent results and insights from the field with a focus on the following mechanisms:(a)alterations in neuronal excitability during acute exercise;(b)alterations in neuronal excitability after chronic exercise;(c)exercise-induced changes in neuronal membrane properties via modulation of ion channel activity;(d)exercise-enhanced dendritic plasticity;and(e)exercise-induced alterations in neuronal gene expression and protein *** hope is to update the community with a cellular and molecular understanding of the recent mechanisms underlying the adaptability of the vertebrate locomotor system in response to both acute and chronic physical exercise.

关键词： Dendritic plasticity Excitability exercise Ion channel modulation Neuron adaptation

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Self-healing hydrogels for enhancing chemotherapy drug efficacy: Advancements in anti-sarcoma and carcinoma therapies and clinical trial feasibility

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Cancer Pathogenesis and Therapy 2024年第2期2卷 132-134页

作者： Luc Taylor Cerebrovascular health Exerciseand Environmental Research Sciences(CHEERS)LaboratoryDepartment of Exercise SciencePhysical and Health EducationFaculty of EducationUniversity of VictoriaVictoriaBC V8W2Y2Canada

HIGHLIGHTS·Site-specific administration is key for optimizing anticancer drug administration;self-healing hydrogels may allow this at reasonable costs and reproducibility.·Self-healing hydrogels have several real-world therapeutic applications,including drug administration.·Self-healing hydrogels are yet to be utilized for chemotherapy drug administration in clinical trials.

关键词： healing clinical chemotherapy

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Predictive Ability of Hypertriglyceridemic Waist,Hypertriglyceridemic Waist-to-Height Ratio,and Waist-to-Hip Ratio for Cardiometabolic Risk Factors Clustering Screening among Chinese Children and Adolescents

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Biomedical and Environmental Sciences 2024年第3期37卷 233-241页

作者： XIAO Tian Li YUAN Shu Qian GAO Jing Yu Julien SBaker YANG Yi De WANG Xi Jie ZHENG Chan Juan DONG Yan Hui ZOU Zhi Yong Key laboratory of Molecular Epidemiology of Hunan Province School of MedicineHunan Normal UniversityChangsha 410081HunanChina The Institute of Interdisciplinary Studies Hunan Normal UniversityChangsha 410013HunanChina Chenzhou First People's Hospital Chenzhou 423000HunanChina Centre for health and exercise Science Research Hong Kong Baptist UniversityKowloon TongHong Kong 999077China Department of Sport Physical Education and HealthHong Kong Baptist UniversityKowloon TongHong Kong 999077China Vanke School of Public health Tsinghua UniversityBeijing 100084China Institute of Child and Adolescent health School of Public HealthPeking University Health Science CenterBeijing 100191China

Objective Hypertriglyceridemic waist(HW),hypertriglyceridemic waist-to-height ratio(HWHtR),and waist-to-hip ratio(WHR)have been shown to be indicators of cardiometabolic risk ***,it is not clear which indicator is more suitable for children and *** aimed to investigate the relationship between HW,HWHtR,WHR,and cardiovascular risk factors clustering to determine the best screening tools for cardiometabolic risk in children and *** This was a national cross-sectional *** and biochemical variables were assessed in approximately 70,000 participants aged 6–18 years from seven provinces in ***,physical activity,dietary intake,and family history of chronic diseases were obtained through ***,χ2 and logistic regression analysis was *** A significant sex difference was observed for HWHtR and WHR,but not for HW *** risk of cardiometabolic health risk factor clustering with HW phenotype or the HWHtR phenotype was significantly higher than that with the non-HW or non-HWHtR phenotypes among children and adolescents(HW:OR=12.22,95%CI:9.54-15.67;HWHtR:OR=9.70,95%CI:6.93-13.58).Compared with the HW and HWHtR phenotypes,the association between risk of cardiometabolic health risk factors(CHRF)clustering and high WHR was much weaker and not significant(WHR:OR=1.14,95%CI:0.97-1.34).Conclusion Compared with HWHtR and WHR,the HW phenotype is a more convenient indicator with higher applicability to screen children and adolescents for cardiovascular risk factors.

关键词： Hypertriglyceridemic waist Waist-to-hip ratio Children and adolescents China Hypertriglyceridemic waist-to-height ratio Cardiovascular risk factors

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The anti-inflammatory effects of exercise on autoimmune diseases:A 20-year systematic review

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Journal of Sport and health Science 2024年第3期13卷 353-367,I0001页

作者： Beibei Luo Dao Xiang Xiaorong Ji Xuan Chen Rui Li Shuxin Zhang Yujun Meng David C.Nieman Peijie Chen School of exercise and health Shanghai University of SportShanghai 200438China Shanghai Key laboratory of Human Performance Shanghai University of SportShanghai 200438China Department of Diving and Hyperbaric Medicine Naval Medical CenterShanghai 200433China National Key laboratory of Immunity and Inflammation Naval Medical UniversityShanghai 200433China Human Performance laboratory Appalachian State UniversityNorth Carolina Research CampusKannapolisNC 28081USA Research Institute for Doping Control Shanghai University of SportShanghai 200438China

Background:The anti-inflammatory effect of exercise may be an underlying factor in improving several autoimmune *** aim of this systematic review was to examine the evidence on the role of exercise training in mitigating inflammation in adolescents and adults with autoimmune ***:PubMed,Web of Science,and Embase databases were systematically reviewed for related studies published between January 1,2003,and August 31,*** randomized and non-randomized controlled trials of exercise interventions with autoimmune disease study participants that evaluated inflammation-related biomarkers were *** quality of evidence was assessed using the Tool for the assEssment of Study qualiTy and reporting in exercise scale and Cochrane bias risk ***:A total of 14,565 records were *** screening the titles,abstracts,and full texts,87 were eligible for the systematic *** studies were conducted in 25 different countries and included a total of 2779 participants(patients with autoimmune disease,in exercise or control groups).Overall,the evidence suggests that inflammation-related markers such as C-reactive protein,interleukin 6,and tumor necrosis factor a were reduced by regular exercise *** exercise interventions combined with multiple exercise modes were associated with greater ***:Regular exercise training by patients with autoimmune disease exerts an anti-inflammatory *** systematic review provides support for the promotion and development of clinical exercise intervention programs for patients with autoimmune *** patients with autoimmune disease can safely adopt moderate exercise training protocols,but changes in inflammation biomarkers will be modest at *** exercise interventions are ineffective or even modestly but transiently pro-inflammatory.

关键词： Autoimmune diseases Cytokines Inflammation Physical activity Training

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Diet restriction and exercise alleviate cognitive reduction of high fat diet(HFD)-induced obese mice by rescuing inflammation-mediated compromised insulin signaling pathway through activating AMPK/SIRT1 signal pathway and suppressing TLR4 signal pathway

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Food Science and Human Wellness 2024年

作者： Hu Zhang Ye Zhang Jiling Liang Jiahang Li Miao He Xin Liu Jielun Huang Minghui Wang Jingjing Fan Ning Chen Tianjiu Research and Development Center for exercise Nutrition and Foods Hubei Key laboratory of exercise Training and Monitoring College of Sports Medicine Wuhan Sports University Physical Education Institute Hubei University of Science and Technology

Obesity， caused by excessive energy， leads to body weight gain and various diseases， including cognitive impairment. Current studies suggest that diet restriction such as optimal fasting and regular exercise are crucial for improving cognitive capacity. However， further exploration is needed to understand the specific mechanisms of high fat diet (HFD)-induced cognitive decline in obesity. In the present study， 4-month-old mice were subjected to HFD feeding for 18 weeks， followed by aerobic exercise and high-intensity intermittent exercise， regular diet feeding， and intermittent fasting for 8 weeks， and then used to evaluate cognitive capacity， inflammation， compromised insulin signaling pathway， oxidative stress， and apoptosis in hippocampal tissue， as well as AMPK/SIRT1 and TLR4 signal pathways. Obese mice revealed impaired cognitive capacity as compared with mice fed with regular diets. In contrast， aerobic exercise， high-intensity intermittent exercise， regular diet， and intermittent fasting could inhibit apoptosis caused by inflammation-mediated compromised insulin signaling pathway in hippocampal tissues through activating the AMPK/SIRT1 signal pathway and suppressing the TLR4 signal pathway， thereby rescuing the cognitive impairment of obese mice. Therefore， diet restriction and exercise interventions may play a positive role in reverting obesity-induced cognitive impairment.

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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and health Science 2024年第2期13卷 145-159页

作者： Paulo Ricardo Prado Nunes Pamela Castro-e-Souza Anselmo Alves de Oliveira Bruno de Freitas Camilo Gislaine Cristina-Souza Lucio Marques Vieira-Souza Marcelo Augusto da Silva Carneiro Department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil exercise and Nutrition Research Group(GPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical exercise Study and Research Group(GEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(CG) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;GRADE:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to CG,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

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