咨询与建议

限定检索结果

文献类型

  • 12,518 篇 期刊文献
  • 1,514 篇 会议

馆藏范围

  • 14,032 篇 电子文献
  • 0 种 纸本馆藏

日期分布

学科分类号

  • 9,904 篇 医学
    • 4,639 篇 临床医学
    • 3,071 篇 药学(可授医学、理...
    • 2,658 篇 中西医结合
    • 1,213 篇 中药学(可授医学、...
    • 531 篇 基础医学(可授医学...
    • 383 篇 公共卫生与预防医...
    • 163 篇 医学技术(可授医学...
    • 102 篇 中医学
  • 3,820 篇 工学
    • 2,073 篇 化学工程与技术
    • 1,086 篇 材料科学与工程(可...
    • 447 篇 生物工程
    • 353 篇 生物医学工程(可授...
    • 132 篇 计算机科学与技术...
    • 122 篇 食品科学与工程(可...
    • 93 篇 机械工程
    • 71 篇 软件工程
    • 64 篇 电子科学与技术(可...
    • 64 篇 轻工技术与工程
    • 60 篇 环境科学与工程(可...
    • 58 篇 控制科学与工程
  • 3,203 篇 理学
    • 1,732 篇 化学
    • 779 篇 生物学
    • 580 篇 物理学
  • 875 篇 农学
    • 320 篇 兽医学
    • 264 篇 作物学
    • 81 篇 植物保护
    • 77 篇 畜牧学
    • 50 篇 农业资源与环境
  • 131 篇 管理学
    • 74 篇 管理科学与工程(可...
  • 90 篇 经济学
    • 90 篇 应用经济学
  • 43 篇 文学
  • 24 篇 教育学
  • 15 篇 法学
  • 6 篇 历史学
  • 4 篇 哲学
  • 4 篇 艺术学

主题

  • 358 篇 drug delivery
  • 324 篇 cancer
  • 174 篇 drug
  • 167 篇 drug resistance
  • 147 篇 drugs
  • 109 篇 covid-19
  • 106 篇 apoptosis
  • 101 篇 delivery
  • 99 篇 immunotherapy
  • 86 篇 self-assembly
  • 86 篇 traditional chin...
  • 79 篇 photodynamic the...
  • 79 篇 molecular dockin...
  • 73 篇 nanoparticles
  • 68 篇 diabetes
  • 65 篇 acid
  • 65 篇 photothermal the...
  • 65 篇 resistance
  • 63 篇 drug discovery
  • 60 篇 synthesis

机构

  • 227 篇 university of ch...
  • 39 篇 centre for drug ...
  • 34 篇 state key labora...
  • 34 篇 key laboratory o...
  • 30 篇 state key labora...
  • 28 篇 state key labora...
  • 27 篇 state key labora...
  • 26 篇 state key labora...
  • 26 篇 state key labora...
  • 25 篇 university of ch...
  • 25 篇 state key labora...
  • 23 篇 tangshan food an...
  • 23 篇 wuya college of ...
  • 23 篇 national institu...
  • 22 篇 key laboratory o...
  • 21 篇 state key labora...
  • 20 篇 key laboratory o...
  • 20 篇 state key labora...
  • 19 篇 national institu...
  • 19 篇 school of busine...

作者

  • 74 篇 lei wang
  • 62 篇 li zhang
  • 57 篇 wei li
  • 47 篇 wei liu
  • 46 篇 li li
  • 44 篇 li yang
  • 43 篇 jing zhang
  • 43 篇 yuanjin zhao
  • 40 篇 rui wang
  • 38 篇 xiawei wei
  • 34 篇 hui wang
  • 33 篇 jun wang
  • 33 篇 jun zhang
  • 30 篇 tao gong
  • 29 篇 yi wang
  • 28 篇 yu wang
  • 28 篇 du guan-hua
  • 27 篇 jie li
  • 27 篇 rui liu
  • 26 篇 xi chen

语言

  • 12,848 篇 英文
  • 1,184 篇 中文
检索条件"机构=Drug Development Laboratory"
14032 条 记 录,以下是1-10 订阅
排序:
Zoledronate-loaded aluminum salt nanovaccines amplify cellular immune response by enhancing cross-presentation
收藏 引用
Nano Research 2025年 第1期18卷 559-571页
作者: Chunting He Penghui He Xue Tang Shuting Bai Ming Qin Yunting Zhang Zhaofei Guo Guangsheng Du Xun Sun Key laboratory of drug-Targeting and drug Delivery System of the Education Ministry West China School of PharmacySichuan UniversityChengdu 610041China
Being a Th2 stimulator,classic aluminum salt-based adjuvants only stimulate weak cellular immune responses that are required for vaccination against intracellular viruses or cancerous *** a thirdgeneration bisphosphon... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Lipid droplets in the nervous system:involvement in cell metabolic homeostasis
收藏 引用
Neural Regeneration Research 2025年 第3期20卷 740-750页
作者: Yuchen Zhang Yiqing Chen Cheng Zhuang Jingxuan Qi Robert Chunhua Zhao Jiao Wang School of Life Sciences Shanghai UniversityShanghaiChina School of Medicine Shanghai UniversityShanghaiChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic MedicinePeking Union Medical CollegeBeijingChina Center of Excellence in Tissue Engineering Chinese Academy of Medical SciencesBeijingChina Beijing Key laboratory of New drug development and Clinical Trial of Stem Cell Therapy BeijingChina
Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous *** droplet formation begins with the synthesis of neutral lipids in the endoplasmic ***,lipi... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Progress and perspectives on targeting nanoparticles for brain drug delivery
收藏 引用
Acta Pharmaceutica Sinica B 2016年 第4期6卷 268-286页
作者: Huile Gao Key laboratory of drug Targeting and drug Delivery Systems West China School of Pharmacy Sichuan University
Due to the ability of the blood–brain barrier(BBB) to prevent the entry of drugs into the brain, it is a challenge to treat central nervous system disorders pharmacologically. The development of nanotechnology provid... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies
收藏 引用
Neural Regeneration Research 2025年 第4期20卷 917-935页
作者: Dian Jiao Lai Xu Zhen Gu Hua Yan Dingding Shen Xiaosong Gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key laboratory of Advanced drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina
Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilep... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and treatment
收藏 引用
Asian Journal of Pharmaceutical Sciences 2019年 第4期14卷 380-390页
作者: Lin Qin Huile Gao Key laboratory of drug Targeting and drug Delivery System of the Education Ministry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology West China School of Pharmacy Sichuan University
Nitric oxide(NO) shows great role in tumor biology. Recent years, more and more researches utilized NO donor in tumor targeting drug delivery and treatment. In this review, we summarized the NO donors by their endogen... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders
收藏 引用
Neural Regeneration Research 2025年 第5期20卷 1258-1276页
作者: Qing Qiu Mengting Yang Danfeng Gong Haiying Liang Tingting Chen Department of Pharmacology School of PharmacyNantong UniversityNantongJiangsu ProvinceChina Jiangsu Province Key laboratory of Inflammation and Molecular drug Target NantongJiangsu ProvinceChina Department of Pharmacy Longyan First Affiliated Hospital of Fujian Medical UniversityLongyanFujian ProvinceChina
The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central n... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Challenges and trends in apomorphine drug delivery systems for the treatment of Parkinson's disease
收藏 引用
Asian Journal of Pharmaceutical Sciences 2018年 第6期13卷 507-517页
作者: Nrupa Borkar Huiling Mu René Holm Department of Pharmacy Faculty of Health and Medical Sciences University of Copenhagen drug Product development Janssen Research and Development Johnson & Johnson
Parkinson's disease(PD) is a chronic debilitating disease affecting approximately 1% of the population over the age of 60. The severity of PD is correlated to the degree of dopaminergic neuronal loss. Apomorphine has ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Theranostic nanoparticles with tumor-specific enzyme-triggered size reduction and drug release to perform photothermal therapy for breast cancer treatment
收藏 引用
Acta Pharmaceutica Sinica B 2019年 第2期9卷 410-420页
作者: Rui Liu Chuan Hu Yuanyuan Yang Jingqing Zhang Huile Gao Key laboratory of drug Targeting and drug Delivery System of the Education Ministry Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology West China School of PharmacySichuan University Chongqing Research Center for Pharmaceutical Engineering Chongqing Medical University
Although progress has been indeed made by nanomedicines, their efficacies for cancer treatment remain low, consequently leading to failures in translation to clinic. To improve the drug delivery efficiency,nanoparticl... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses
收藏 引用
Traditional Medicine Research 2025年 第2期10卷 55-64页
作者: Jin-Fang Wu Yi-Sheng Chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key laboratory of Toxicant and drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central laboratory Jiangsu Province Geriatric HospitalNanjing 210024China
Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditio... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Targeting epigenetic regulators to overcome drug resistance in cancers
收藏 引用
Signal Transduction and Targeted Therapy 2023年 第3期8卷 1070-1093页
作者: Nan Wang Ting Ma Bin Yu Institute of drug Discovery&development School of Pharmaceutical SciencesZhengzhou UniversityZhengzhou 450001China
drug resistance is mainly responsible for cancer recurrence and poor *** regulation is a heritable change in gene expressions independent of nucleotide sequence *** the common epigenetic regulation mechanisms,DNA meth... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论