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A comparative study on design standards of screw conveyors in China,Germany,and the USA–Part II:Discrete element method

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Particuology 2024年第9期92卷 113-125页

作者： Yuan Tan Michael Rackl Weijie Yang Johannes Fottner Wenjun Meng stephan Kessler Technical University of Munich Chair for Materials HandlingMaterial FlowLogisticsGarchingGermany Ibracon–Ingenieurbüro dr.-Ing.Rackl ZornedingGermany School of Mechanical Engineering Taiyuan University of Science and TechnologyTaiyuanChina

This part of the study aims to evaluate the advantages and disadvantages of technical standards of screw conveyors in China,Germany,and the USA for industrial *** source or determination method of empirical coefficients as well as the theoretical foundation of dimensioning-relevant diagrams in these standards is not explicitly documented in the ***,instead of less efficient on-site tests,the numerical simulation by discrete element method is *** on the geometrical and operational designs determined in three standards for horizontal,slightly inclined,and vertical conveyance of three representative bulk solids(barley,lignite,and sand),the potential influencing factors are *** constant particle and contact parameters,the potential deviations caused by particle models are ***,the accuracy of power consumption calculation of each standard and the divergence between accessible and required mass flows is comprehensively assessed based on the analysis of simulated *** main conclusions are dr.wn:(1)Particle fall back is barely considered by all three standards and leads to overestimated mass throughput;(2)The decrease in mass throughput caused by an increasing degree of filling can be compensated by slowing down the rotational speed.

关键词： Discrete element method Design standard Screw conveyor Screw auger Bulk solid

Minimally Invasive Total Arterial Coronary Artery Bypass Grafting in Left main stem Disease

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World Journal of Cardiovascular Surgery 2024年第7期14卷 107-114页

作者： Pradeep Nambiar Radwan Husseini Prashant Sagar dr. Sulaiman Al Habib Hospital Dubai UAE Aster Hospital Dubai UAE

Objective: The aim was to show that Minimally Invasive total arterial revascularization for left main stem coronary artery disease, via a left anterior Mini thoracotomy using bilateral internal thoracic arteries is feasible, reproducible and safe. Further, there has been no exclusive data or experience with minimally invasive coronary artery bypass grafting in left main stem disease. Methods: From April 2019 to March 2024, 41 patients with left main stem stenosis, left main equivalent disease and unprotected left main with triple vessel disease underwent off pump minimally invasive multivessel coronary artery bypass grafting using either in situ pedicled Bilateral Internal Thoracic arteries or Left and Right Internal Thoracic artery Y composite conduits at three centers. Bilateral Internal Thoracic arteries were harvested under direct vision. All patients had an Intra-Aortic Balloon Pump inserted via the femoral artery prior to induction of anesthesia, to prevent any hemodynamic instability, arrhythmias, and was removed following completion of the procedure in the operating room without any complications. Efficacy and outcomes were evaluated by i) Primary (MACCE)-Major Adverse Cardiac and Cardiovascular events and ii) Secondary outcome measures including total length of stay, return to full physical activity and quality of life. Mean follow-up was 1.4 years (Maximum was 2.5 years). Results: 41 patients with left main stem coronary artery stenosis, underwent total arterial revascularization using bilateral internal thoracic arteries. Left main stem stenosis was present in 29 patients, Unprotected left main stem stenosis with triple vessel disease in 7 and left main equivalence in 5 patients. In this cohort, 29 patients with only left main stem stenosis had 2 grafts each, 7 patients with left main and triple vessel disease had 3 grafts and 5 patients with left main equivalent disease had 2 grafts respectively. The average number of grafts was 2.2. One patient was conv

关键词： Left main stem Minimally Invasive CABG Bilateral Internal Mammary Arteries

Novel insights on oral squamous cell carcinoma management using long non-coding RNAs

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Oncology Research 2024年第10期32卷 1589-1612页

作者： SUBHAYAN SUR DIMPLE DAVRAY SOUMYA BASU SUPRIYA KHEUR JAYANTA KUMAR PAL SHUCHI NAGAR AVINASH SANAP BHIMAPPA MRUDAGI SAMIR GUPTA Cancer and Translational Research Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethTathawadePune411033India Bioinformatics Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethPune411033India Department of Oral Pathology and Microbiology Dr.D.Y.Patil Dental College&HospitalDr.D.Y.Patil VidyapeethPune411018India Department of Surgical Oncology Dr.D.Y.Patil Medical CollegeHospital&Research CentreDr.D.Y.Patil VidyapeethPune411018India

Oral squamous cell carcinoma(OSCC)is one of the most prevalent forms of head and neck squamous cell carcinomas(HNSCC)with a poor overall survival rate(about 50%),particularly in cases of ***-based cancer biomarkers are a relatively advanced concept,and non-coding RNAs currently have shown promising roles in the detection and treatment of various *** review underlines the function of long non-coding RNAs(lncRNAs)in the OSCC and its subsequent clinical ***,a class of non-coding RNAs,are larger than 200 nucleotides and resemble mRNA in numerous ***,unlike mRNA,lncRNA regulates multiple dr.ggable and non-dr.ggable signaling molecules through simultaneous interaction with DNA,RNA,proteins,or microRNAs depending on concentration and localization in *** of oncogenic lncRNAs and downregulation of tumor suppressor lncRNAs are evident in OSCC tissues and body fluids such as blood and saliva indicating their potential as valuable *** inhibition of candidate oncogenic lncRNAs or overexpression of tumor suppressor lncRNAs showed potential therapeutic roles in in-vivo animal *** types of lncRNAs that are expressed differentially in OSCC tissue and bodily fluids have been systematically documented with specificity and *** review thoroughly discusses the biological functions of such lncRNAs in OSCC cell survival,proliferation,invasion,migration,metastasis,angiogenesis,metabolism,epigenetic modification,tumor immune microenvironment,and dr.g ***,we addr.ssed the diagnostic and therapeutic importance of lncRNAs in OSCC pre-clinical and clinical systems,providing details on ongoing research and outlining potential future directions for advancements in this *** essence,this review could be a valuable resource by offering comprehensive and current insights into lncRNAs in OSCC for researchers in fundamental and clinical domains.

关键词： Oral squamous cell carcinoma(OSCC) Head and neck cancer Non-coding RNA Long non-coding RNA(lncRNA) Cancer diagnosis

How optimized emitter design leads to saturated color highperformance organic light-emitting diodes

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Science China Chemistry 2024年第1期67卷 314-315页

作者： Eli Zysman-Colman Organic Semiconductor Centre EaStCHEM School of ChemistryUniversity of St AndrewsSt AndrewsFifeKY169STUK

In an article recently published in *** Chem.,Liao,Jiang,and their co-workers[1]report two N/carbonyl-based multi-resonant thermally activated delayed fluorescence(MR-TADF)emitters,the organic light-emitting diode(OLED)that uses one of these,MTDMQAO,showed record maximum external quantum efficiencies(EQEmax)for devices using this class of *** reason for this impressive device performance stems from a rationale and judicious molecular design,building on a core QAO(aka DiKTa)[2]MR-TADF emitter structure that the authors helped to pioneer[3,4],and decorating a fused derivative of it with an electron-withdr.wing triazine unit.

关键词： emitter diodes saturated

Palaeogene Sandstones of the Manika Plateau in Kolwezi (dr.Congo): Sedimentological and Geochemical Characterization, Provenance, Palaeoalteration and Tectonic Context

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Open Journal of Geology 2024年第7期14卷 705-722页

作者： Pierre T. Mashala Faidance Mashauri Samy M. Malango Christian K. Mulopwe Department of Geology University of Lubumbashi Haut-Katanga DR Congo Department of Geology University of Ul Haut-Ul DR Congo Department of Geology and Technology University of Kolwezi Lualaba DR Congo

This work presents a study of the Paleogene sandstones of the Manika plateau in Kolwezi, dr.Congo. These sandstones belong to the “Grès polymorphes” group, which together with the overlying “Sables ocre” makes up the Kalahari Supergroup. Sedimentological and geochemical analyses have enabled us to characterize these sandstones and determine their origin, the conditions of their formation and the tectonic context in which they were developed. The results show that the sandstones are quartz arenites with a high level of mineralogical, textural and chemical maturity. They are recycled sandstones, formed in an intracratonic sedimentary basin, in the context of a passive continental margin, after a long fluvial transport of sediments. These sandstones initially come from intense alteration of magmatic rocks with felsic composition, mainly tonalite-trondhjemite-granodiorite (TTG) complexes, in hot, humid palaeoclimatic conditions and oxidizing environments.

关键词： Sandstone Sedimentology Geochemistry Palaeoalteration Tectonic Context Manika Plateau dr.Congo

Minimally Invasive Surgery for Necrotizing Pancreatitis: A Case Report

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Surgical Science 2024年第9期15卷 514-521页

作者： Néstor Veriel Méndez Huerta Luis Fernando Zorrilla Núñez Noelia Obregón Gaxiola César Jair Treviño Arizmendi Gerardo Iván Muñoz Morales Marco Alejandr. Arizmendi Villarreal Pamela Denisse Valdez Navarro Marco Antonio Hernández Guedea Gerardo Enrique Muñoz Maldonado Service of General Surgery Hospital Universitario Dr. Jos Eleuterio Gonzlez Universidad Autnoma de Nuevo Len Monterrey Mxico

Introduction: Necrotizing pancreatitis management is complex and varies significantly among clinicians. Minimally invasive approaches like transgastric necrosectomy via laparoscopy are emerging as effective treatment options. This case report underscores the technique’s efficacy, clinical outcomes, and role in reducing complications. Clinical Observation: A 59-year-old male with a history of smoking and alcoholism presented with severe abdominal pain, nausea, and vomiting. Over the following weeks, he developed symptoms including asthenia, weight loss, and melena. Diagnostic workup revealed severe anemia and Balthazar E necrotizing pancreatitis, with significant intra-abdominal fluid collections and signs of infection. After initial conservative management, the patient underwent transgastric necrosectomy via laparoscopy due to deteriorating clinical status. The procedure involved removing necrotic tissue and performing a cystogastroanastomosis and jejunostomy. Postoperative care included fasting, parenteral nutrition, broad-spectrum antibiotics, and enzymatic replacement. The patient recovered well, with reduced necrotic tissue on follow-up imaging, and was discharged twelve days post-surgery [1]. Conclusion: Transgastric necrosectomy by laparoscopy is a valuable first-line surgical option for patients with symptomatic necrotizing pancreatitis, particularly in cases without prior interventions. This minimally invasive technique helps reduce major complications and mortality, offering a less invasive alternative to traditional open necrosectomy. The multidisciplinary approach and careful postoperative management were crucial to the patient’s favorable outcome. The case highlights the potential of transgastric necrosectomy as an effective treatment strategy in managing complex pancreatitis cases, including those with associated duodenal perforation [2].

关键词： Necrotizing Transgastric Pancreatic Necrosectomy Pancreatitis Case Report

Enhancing Patient Safety in the Operating Room: A Comprehensive Guide from a Nurse’s Perspective

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Open Journal of Nursing 2024年第6期14卷 252-266页

作者： Aisha Mohamed Hussein Operating Room Nurse Dr. Sulaiman Al-Habib Medical Group Bone Joint and Spine Hospital Riyadh Saudi Arabia

Ensuring patient safety within the operating room is a paramount concern in contemporary healthcare, and this guide aims to provide an in-depth exploration of this crucial aspect from the perspective of nurses. Nurses play a pivotal role in supporting surgeons and maintaining a safe environment for patients undergoing various medical procedures.

关键词： Operating Room Patient Safety Nurses

Green Hydr.gen: Perspectives and Challenges in Using the Natural Gas Network in Ceará/Brazil

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Journal of Geoscience and Environment Protection 2024年第3期12卷 70-94页

作者： Francisco Alfredo de Castro Mona Lisa Moura de Oliveira Lutero Carmo de Lima Daniel Silveira Serra Science and Technology Center State University of Ceará Ceará Brazil Av. dr. Silas Munguba 1700 Fortaleza-Ceará Brazil

Climate change, mainly caused by the use of non-renewable fuels, has raised global concerns and led to the search for less polluting energy sources, making hydr.gen a promising energy alternative with the potential to contribute to changes in the energy mix of various countries through the use of technologies that enable its production and use with low or zero carbon emissions. In this context, Brazil has aroused great interest from other countries in exploring its renewable resources for the production of hydr.gen (green hydr.gen). In this sense, the use of natural gas pipelines and the use of hydr.gen in mixtures with natural gas have become the subject of studies due to their economically viable alternative for the immediate use of this energy vector. However, there are still technical and regulatory challenges regarding the integration of hydr.gen into the existing natural gas pipeline network. In this context, the present study aims to addr.ss the effects of hydr.gen interaction with the structure of natural gas pipeline steel and the regulatory barriers to the use of this network for the transportation of green hydr.gen, particularly in the state of Ceará/Brazil. After extensive analysis of literature and regulatory documents, it was concluded that: 1) Ceará/Brazil has strong potential to meet the demand for green hydr.gen through the use of solar and wind energy sources;2) there is feasibility for the adaptation or conversion of natural gas infrastructure for the transportation of green hydr.gen;3) discussions regarding the regulatory competence of green hydr.gen transportation and distribution through the natural gas network in Brazil are still incipient;4) the current regulation of the natural gas industry can serve as a subsidy for the regulation of green hydr.gen and natural gas transportation.

关键词： Decarbonization Natural Gas Green Hydr.gen Pipelines

Real World Evidence (RWE, Real World Data), of the Effectiveness of Amoxicillin-Clavulanate in the Treatment of Childr.n with Upper Respiratory Tract Infections (Tonsillitis, Otitis, Sinusitis)

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Open Journal of Respiratory Diseases 2024年第3期14卷 77-89页

作者： Maria Gonzalez Yibirin Juan Chirinos David Alberto Rincón Matute Trinidad Coll Miriam Rosales Yuliana Guevara Kuanlin Doried Guitens Pérez Mauribel Figueroa Rosalía Romero Jurgensen Andr.a Rojas Gabriel Jesús Arismendi González Milagros Salcedo Marife Martina Marin Marcano Carolina Mendoza Marycarmen Anuel Maria Morao Raymond Aguilera Diego Ríos Maryenis Rodr.guez Loren Sánchez Jennyfer Fernández Rafael González Zaidith Zerpa Nelson Rodr.guez Mirluis Rojas Sixtaime Quijada Mariangel Moya Diego Orsini Chris Gómez Hector Gamero José Rodr.guez Laboratorios LETI S.A.V. Guarenas Venezuela Ambulatorio Rural tipo II CPT3 Pampatar Venezuela Ambulatorio Los Robles CPT dr. Luis Rosas Bravo Los Robles Venezuela Clnica Prevaler Pampatar Venezuela Hospital tipo 1 Dr. David Espinoza Rojas en Salamanca Salamanca Venezuela Centro Mdico Rotary El Valle Venezuela Ambulatorio Rural Tipo II CPT3 dr. Enrique Albornoz Lares La Asuncin Venezuela

Real-world evidence (RWE) is clinical evidence on a medical product’s safety and efficacy that is generated using real-world data (RWD) resulting from routine healthcare delivery. This study evaluates the clinical efficacy of amoxicillin + clavulanic acid in childr.n with pharyngitis, acute otitis, or acute rhinosinusitis with suspected bacterial origin under normal office and home conditions. Methods: This was a real-life, prospective, observational, pharmacovigilance study. It included childr.n of both sexes between 2 and 12 years old, with a diagnosis of Rhinopharyngitis (tonsillitis), Acute Otitis Media and Rhinosinusitis. The main effectiveness variable evaluated was reduction and time to resolution of symptoms. All patients received Amoxicillin/Clavulanic Acid suspension 600 mg/42.9 mg/5 mL at a dose of 90 mg/Kg/day in two doses, every 12 hours for 7 days. The evaluations were carried out at the beginning, at 72 hours (3rd day) and at 7 days. All patients underwent culture and antibiogram. Results: The majority of cultures were negative for pathogenic germs, suspecting unidentifiable germs, or viral etiology despite the rigorous selection of subjects following validated scores. The most frequently isolated germ was staphylococcus aureus;growth of gram-negative bacteria was reported in 33.33% of the cultures. There was a significant improvement in symptoms in childr.n with tonsillitis and rhinosinusitis from the first 72 hours of treatment, persisting until the 7 days. In the otitis media group, returning to normal by the tenth day. During the conduction of this investigation, no adverse effects associated with the prescribed therapy were reported.

关键词： Amoxicillin Clavulanic Acid Tonsillitis Otitis Sinusitis