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检索条件"机构=Departments of Biochemistry and Molecular Genetics"
160 条 记 录,以下是1-10 订阅
排序:
Contemporary Approaches for Identifying Rare Bone Disease Causing Genes
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Bone Research 2013年 第4期1卷 301-310页
作者: Charles R.Farber Thomas L.Clemens Center for Public Health Genomics University of Virginia departments of Public Health Sciences and biochemistry and molecular genetics University of Virginia Department of Orthopaedic Surgery Johns Hopkins School of Medicine Baltimore Veterans Administration Medical Center
Recent improvements in the speed and accuracy of DNA sequencing, together with increasingly sophisti- cated mathematical approaches for annotating gene networks, have revolutionized the field of human genetics and mad... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Effects of epoxyeicosatrienoic acids on levels of eNOS phosphorylation and relevant signaling transduction pathways involved
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Science China(Life Sciences) 2005年 第5期48卷 495-505页
作者: CHEN Ruijuan1, JIANG Jiangang1, XIAO Xiao2 & WANG Daowen1 1. The Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China 2. departments of molecular genetics and biochemistry & Gene Therapy Center, University of Pittsburgh, Pittsburgh, PA, USA 1. The Institute of Hypertension and Department of Internal Medicine Tongji Hospital Tongji Medical College Huazhong University of Science & Technology 430030 Wuhan China 2. departments of molecular genetics and biochemistry & Gene Therapy Center University of Pittsburgh Pittsburgh PA USA
Endothelial nitric oxide synthase (eNOS) is a key enzyme responsible for the regu-lation of vascular homeostasis. Many humor factors and mechanical forces can affect eNOS ac-tivity via phosphorylation modification but... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal cancer
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World Journal of Gastroenterology 2016年 第30期22卷 6764-6775页
作者: Simona Gurzu Camelia Silveanu Annamaria Fetyko Vlad Butiurca Zsolt Kovacs Ioan Jung Department of Pathology University of Medicine and Pharmacy of Tirgu-Mures Department of Surgery University of Medicine and Pharmacy of Tirgu-Mures departments of genetics and biochemistry University of Medicine and Pharmacy of Tirgu-Mures
Epithelial-to-mesenchymal transition(EMT) is defined as the transformation of an epithelial cell into a spindle cell with the loss of membrane E-cadherin expression and the gain of mesenchymal markers positivity. In t... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Writing and erasing MYC ubiquitination and SUMOylation
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Genes & Diseases 2019年 第4期6卷 359-371页
作者: Yingxiao Chen Xiao-Xin Sun Rosalie C.Sears Mu-Shui Dai departments of molecular&Medical genetics School of MedicineOHSU Knight Cancer InstituteOregon Health&Science University3181 SW Sam Jackson Park RoadPortlandOR 97239USA
The transcription factor c-MYC(MYC thereafter)controls diverse transcription programs and plays a key role in the development of many human *** develop multiple mechanisms to ensure that MYC levels and activity are pr... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
The role of hypogonadism in Klinefelter Syndrome
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Asian Journal of Andrology 2014年 第2期16卷 185-191,I0007页
作者: Christian Host Anne Skakkeb k Kristian A Groth Anders Bojesen departments of Pediatrics Endocrinology and Internal Medicine (MEA) molecular Medicine Cardiology Aarhus University Hospital Aarhus Department of Clinical genetics Vejle Hospital Vejlep Institute of Regional Health Research University of Southern Denmark Odense Denmark.
Klinefelter syndrome (KS) (47, XXY) is the most abundant sex-chromosome disorder, and is a common cause of infertility and hypogonadism in men. Most men with KS go through life without knowing the diagnosis, as on... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
DNA methylome and the complexity, of discovering prostate cancer biomarkers
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Asian Journal of Andrology 2011年 第5期13卷 661-662页
作者: Shahriar Koochekpour departments of Cancer genetics and Urology RoswellPark Cancer Institute Elm and Carlton Streets BuffaloNY 14263 USA
Prostate cancer (PCa) remains the most common malignancy and a leading cause of cancer-related 'deaths in men. molecular discrimination at an early stage between indolent and aggressive primary tumors in pathologic... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Intramuscular delivery of rAAV-mediated kallikrein gene reduces hypertension and prevents cardiovascular injuries in model rats
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Acta Pharmacologica Sinica 2007年 第12期28卷 1898-1906页
作者: Yao WANG~(2,3),Ling-bo HOU~(2,3),Zhen-jun LIU~2,Yan WANG~2,Chun-lian CHEN~2,Xiao XIAO~(2,4),Dao-wen WANG~(2,5)~2 Institute of Hypertension and Department of Internal Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science andTechnology,Wuhan 430030,China ~4 departments of molecular genetics and Biochentistry and Gene Therapy Center University of Pittsburgh,Pittsburgh,PA 15261,USA Institute of Hypertension and Department of Internal Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China departments of molecular genetics and biochemistry and Gene Therapy Center Universit
Aim:The overexpression of the human tissue kallikrein (HK) gene can reduceblood pressure and ameliorate the secondary syndromes associated with hyper-tension in animal *** current study was designed to investigate h... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
The next generation of cancer management
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Cancer Biology & Medicine 2016年 第1期13卷 1-2页
作者: Wayne W.Grody Divisions of Medical genetics and molecular Diagnostics Departments of Pathology & Laboratory Medicine Pediatrics and Human Genetics UCLA School of Medicine UCLA Institute for Society and Genetics Molecular Diagnostic Laboratories and Clinical Genomics Center UCLA Medical Center
As readers of Cancer Biology and Medicine well know,there has been a seismic shift in human molecular biology over the past few years,as momentous in its own way as the discovery of the double-helical structure of DNA... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Glutamate, a metabolic biomarker of aggressiveness and a potential therapeutic target for prostate cancer
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Asian Journal of Andrology 2013年 第2期15卷 212-213页
作者: Shahriar Koochekpour departments of Cancer genetics and Urology Center forGenetics and Pharmacology Roswell Park CancerInstitute Buffalo NY 14263 USA
Glutamate is extensively involved in metabolic and oncogenic pathways. Univariate and multivariate analyses showed that serum glutamate levels directly correlated with Gleason score (≤ 6 vs.≥ 8) and primary prosta...
来源: 维普期刊数据库 维普期刊数据库 评论
Acid–base Homeostasis and Implications to the Phenotypic Behaviors of Cancer
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Genomics, Proteomics & Bioinformatics 2023年 第6期21卷 1133-1148页
作者: Yi Zhou Wennan Chang Xiaoyu Lu Jin Wang Chi Zhang Ying Xu Cancer Systems Biology Center China–Japan Union HospitalJilin UniversityChangchun 130033China Department of biochemistry and molecular Biology and Institute of Bioinformatics University of GeorgiaAthensGA 30602USA Department of Medical and molecular genetics Indiana University School of MedicineIndianapolisIN 46202USA Department of Electrical and Computer Engineering Purdue UniversityWest LafayetteIN 47907USA Department of Biohealth Informatics Indiana University–Purdue University IndianapolisIndianapolisIN 46202USA departments of Chemistry and of Physics and Astronomy Stony Brook UniversityStony BrookNY 11794USA
Acid–base homeostasis is a fundamental property of living cells,and its persistent disruption in human cells can lead to a wide range of *** this study,we conducted a computational modeling analysis of transcriptomic... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论