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Neuroscience & Medicine 2013年第1期4卷 7-15页

作者： Bo-Ra Choi Ju-Hyun Kim Jeong-Uk Lee Junghwan Kim department of physical Therapy College of Public Health & Welfare Yongin University Yongin Korea. Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin University Yongin Korea

The present study was designed to evaluate the effects of hippotherapy on standing balance in patients with incomplete cervical spinal cord injuries. Ten patients (8 men and 2 women) who were diagnosed with cervical levels of injury between 3 and 6, and D according to the ASIA Impairment Scale. All patients were tested by the physiotherapists prior to and after hippotherapy treatment. Standing balance was measured using the Interactive Balance System (IBS). The weight distribution index was significantly increased in application of hippotherapy compared with control groups in patients with a neurologic level of cervical 3 and 4, and with Brown-Sequard syndrome, respectively. However, most of the patients exhibited no significant changes in the standing balance index, such as F1, F2-4, F5-6, F7-8, and SI scores, after hippotherapy. These results suggest that hippotherapy did not have a significant effect on the standing balance of patients with incomplete cervical spinal cord injuries.

关键词： Spinal Cord Injury Standing Balance Hippotherapy

LED-pumped whispering-gallery laser

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Photonics Research 2017年第6期5卷 36-40页

作者： SIMON J.HERR KARSTEN BUSE INGO BREUNIG Laboratory for Optical Systems Department of Microsystems Engineering University of Freiburg Fraunhofer Institute for physical Measurement Techniques IPM

A low-cost light-emitting diode(LED) is sufficient to pump a quasi-continuous-wave bidirectional high-Q whispering-gallery resonator laser made of Nd:YVO_4. This is remarkable because of the very limited spatial and spectral coherence of an LED. The LED, delivering up to 3.5 W, centered around 810 nm, is turned on in intervals of 100 μs duration, and for these periods a laser output exceeding 0.8 mW has been ***, 0.1-s-long laser pulses are demonstrated. To the best of our knowledge, this is the first demonstration of an LED-pumped high-Q whispering-gallery laser. The concept can be extended easily to other laser active materials. A prospect is also to pump several of such lasers with a single LED.

关键词： LED-pumped whispering-gallery laser Nd

The Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation Combined with Range of Motion Exercise on Paretic Hand Function in Female Patients after Stroke

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Neuroscience & Medicine 2013年第2期4卷 77-83页

作者： Mee-Young Kim Ju-Hyun Kim Jeong-Uk Lee Byong-Yong Hwang Junghwan Kim department of physical Therapy College of Public Health & Welfare Yongin University Yongin South Korea. Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin University Yongin South Korea Laboratory of Health Science & Nanophysiotherapy Department of Physical Therapy Graduate School Yongin University Yongin South Korea

Repetitive transcranial magnetic stimulation (rTMS) has recently been demonstrated to improve motor function after stroke. However, no study has yet tested the synergetic effects of physical exercise on rTMS in clinical settings. We investigated the effect of a 6-session course of low frequency rTMS on contralesional primary motor cortex combined with range-of motion (ROM) exercise on paretic hand function in female stroke patients. This was a single-blind study of the effects of rTMS with or without ROM exercise in female hemiplegic patients after stroke. All patients underwent rTMS on the contralesional primary motor cortex for 15 minutes and ROM exercise on the paretic hand. The cortical excitability determined by the amplitude and latency of the motor evoked potential (MEP) was measured in both first dorsal interosseous (FDI) muscles. We also evaluated arm function using Box and Block, arm reach, 9-hole pegboard, power grip, and pinch grip force tests. The rTMS-induced MEP amplitude of the paretic side significantly increased whereas the non-paretic side showed a decrease through every session. However, the MEP latency significantly increased on the non-paretic hand at post-rTMS with exercise, but a tendency of decrement on paretic hand at same application. Motor function showed improvement in the 9-hole pegboard and arm reach tests at post-rTMS with exercise on the paretic side compared with the non-paretic side. A significant correlation was especially noted between motor function and MEP on the paretic side of stroke patients. Low frequency rTMS with ROM exercise improved hand function after stroke. This may, in part, result in additional rehabilitation in stroke patients.

关键词： Repetitive Transcranial Magnetic Stimulation Range of Motion Exercise Stroke Motor Recover

The dislocation structure of slip bands in deformed high entropy alloy nanopillars

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Journal of Materials Science & Technology 2021年第36期95卷 136-144页

作者： Qun Yang Yang Hu Jian-Min Zuo department of Materials Science and Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801United States School of physical Science and Technology Shanghai Tech UniversityShanghai 201210China Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-ChampaignUrbanaIllinois 61801United States

Remarkable diversity is observed in dislocation interactions that are responsible for intermittent and sudden crystal *** large crystal slips can be easily observed on the surface of deformed crystals,unraveling the underlying dislocation interaction mechanisms,however,has been a longstanding challenge in the study of single-crystal plasticity.A recent study demonstrated that the sluggish dislocation dynamics in the high entropy alloy(HEA)of Al_(0.1)CoCrFeNi enables the observation of slip bands for a direct link to dislocation avalanches in a ***,we further examined the dislocation structure of slip bands in the HEA nanopillars oriented for single *** evidence was provided on the dislocation organization in a slip band based on groups of primary dislocations,secondary dislocations,and dislocation *** results were compared with the previously proposed slip band *** unique aspects of the HEA that enable such observations were also investigated through an examination of the dislocation microstructure and its response to applied forces in the HEA nanopillars.

关键词： Crystal plasticity Dislocation structure Nanopillars High entropy alloy Slip band Transmission electron microscopy

Factors influencing the drug release from calcium phosphate cements

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Bioactive Materials 2022年第1期7卷 341-363页

作者： Marco Fosca Julietta V.Rau Vuk Uskokovi Istituto di Struttura della Materia Consiglio Nazionale delle Ricerche(ISM-CNR)Via del Fosso del Cavaliere 10000133RomeItaly I.M.Sechenov First Moscow State Medical University Institute of PharmacyDepartment of AnalyticalPhysical and Colloid ChemistryTrubetskaya 8build.2119991MoscowRussia Advanced Materials and Nanobiotechnology Laboratory TardigradeNano LLCIrvineCA 92604United States

Thanks to their biocompatibility,biodegradability,injectability and self-setting properties,calcium phosphate cements(CPCs)have been the most economical and effective biomaterials of choice for use as bone void *** have also been extensively used as drug delivery carriers owing to their ability to provide for a steady release of various organic molecules aiding the regeneration of defective bone,including primarily antibiotics and growth *** review provides a systematic compilation of studies that reported on the controlled release of drugs from CPCs in the last 25 *** chemical,compositional and microstructural characteristics of these systems through which the control of the release rates and mechanisms could be achieved have been *** doing so,the effects of(i)the chemistry of the matrix,(ii)porosity,(iii)additives,(iv)drug types,(v)drug concentrations,(vi)drug loading methods and(vii)release media have been distinguished and discussed *** specificities of in vivo release of drugs from CPCs have been reviewed,*** the kinetic and mechanistic correlations between the CPC properties and the drug release is a prerequisite for the design of bone void fillers with drug release profiles precisely tailored to the application area and the clinical *** goal of this review has been to shed light on these fundamental correlations.

关键词： Calcium phosphate cements Drug release Release rate Antibiotics release Bone fillers

Cycling hydrogen desorption properties and microstructures of MgH_(2)-AlH_(3)-NbF_(5) hydrogen storage materials

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Rare Metals 2021年第4期40卷 1003-1007页

作者： Xiao-Sheng Liu Hai-Zhen Liu Ning Qiu Yan-Bing Zhang Guang-Yao Zhao Li Xu Zhi-Qiang Lan Jin Guo Guangxi Novel Battery Materials Research Center of Engineering Technology School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Processing for Non-ferrous Metallic and Featured Materials School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Guangxi Colleges and Universities Key Laboratory of Novel Energy Materials and Related Technology School of Physical Science and TechnologyGuangxi UniversityNanning 530004China State Key Laboratory of Advanced Power Transmission Technology Global Energy Interconnection Research Institute Co.LtdBeijing 102209China department of AC Construction State Grid Co.LtdBeijing 100031China State Grid DC Project Construction Branch Company Beijing 100052China

Magnesium hydride(MgH_(2)) is a candidate material for hydrogen ***_(2)-AlH_(3) composite shows superior hydrogen desorption properties than pure MgH_(2).However,this composite still suffers from poor cycling *** this work,NbF_(5) was utilized to improve the cycling properties of the MgH_(2)-AlH_(3) *** hydrogen desorption studies show that NbF_(5) significantly improves the cycling stability of MgH_(2)-AlH_(3).The MgH_(2)-AlH_(3)-NbF_(5) composite can release about 2.7 wt% of hydrogen at 300℃ for 1 h and the hydrogen desorption capacity can maintain at 2.7 wt% for more than100 *** comparison,the hydrogen desorption capacity of the MgH_(2)-AlH_(3) composite is decreasing with the cycle number *** capacity is reduced from a maximum value of 3.3 wt% to about 1.0 wt% after 40 ***-Emmett-Teller(BET) surface area measurements show that the particle size of MgH_(2)-AlH_(3) composite decreases after cycling,which means pulverization of the ***_(5) can to some extent suppress the pulverization of the composite during cycling,which partially contributes to the improvement of the cycling hydrogen desorption properties of the material.

关键词： Hydrogen storage materials Magnesium hydride Aluminum hydride Niobium fluoride Cycling properties

Engineered polyketides:Synergy between protein and host level engineering

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Synthetic and Systems Biotechnology 2017年第3期2卷 147-166页

作者： Jesus F.Barajas Jacquelyn M.Blake-Hedges Constance B.Bailey Samuel Curran Jay.D.Keasling department of Energy Agile BioFoundry EmeryvilleCAUSA department of chemistry University of CaliforniaBerkeleyBerkeleyCA 94720USA Joint BioEnergy Institute EmeryvilleCA 94608USA physical Biosciences Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Comparative Biochemistry Graduate Group University of CaliforniaBerkeleyBerkeleyCA 94720USA QB3 Institute University of CaliforniaBerkeleyEmeryvilleCA 94608USA department of Chemical&Biomolecular Engineering Department of BioengineeringUniversity of CaliforniaBerkeleyBerkeleyCA 94720USA Novo Nordisk Foundation Center for Biosustainability Technical University DenmarkDK2970 HorsholmDenmark

Metabolic engineering efforts toward rewiring metabolism of cells to produce new compounds often require the utilization of non-native enzymatic machinery that is capable of producing a broad range of chemical *** encompass one of the largest classes of chemically diverse natural *** thousands of known polyketides,modular polyketide synthases(PKSs)share a particularly attractive biosynthetic logic for generating chemical *** engineering of modular PKSs could open access to the deliberate production of both existing and novel *** this review,we discuss PKS engineering efforts applied at both the protein and cellular level for the generation of a diverse range of chemical structures,and we examine future applications of PKSs in the production of medicines,fuels and other industrially relevant chemicals.

关键词： Polyketide Polyketide synthase Natural products Commodity chemical Metabolic engineering Synthetic biology

Research and Design of Hurricane Fighting Devices

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Journal of physical Science and Application 2012年第8期2卷 296-300页

作者： Victor Bematskiy Borys Levkovskiy physical and technological department Rivne State Humanitarian University 33028 Ukraine

Hurricane fighting devices are recommended. The devices belong to the sphere of artificial weather conditions changes over the Earth surface. The purpose of the paper is the development of the original design of devices for hurricane fighting. The decreasing of hurricane energy takes place under the reaction of directed air current against the hurricane air current mass. The air current is created by propellers, located in cylindrical frames with nozzles at a current exit. The devices function due to horizontal hurricanes air current. The essential factor lies in absence of influence on ecology. The devices are of simple constructions, it results in simplification of their production technology and lower cost,

关键词： Hurricane tornado devices air current ecology.

Study on JiangXi Province Part of Civilian Run Colleges and Universities Public Sports Teaching Present Situation and Countermeasure

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International Journal of Technology Management 2014年第3期 122-124页

作者： Zhou Bingbing department of physical Education Jiangxi University of Technology Nanchang Jiangxi China

The current,with the sustained and rapid development of education in our country, private colleges and universities gradually become a part of our school,it is one of the indispensable important strength of higher education *** Province in recent years, the pace of development of civilian run colleges and universities continue to *** emergence of this new things,comply with the requirements of the era of reform and opening up,at the same time,it also complies with the demand of talent in our country is in the rapid development of economic society,provides the necessary basic talents for local economic *** all doubt,private colleges and universities in Jiangxi province has become an important part of our province *** the private teaching at the present stage,development of public sports teaching to improve students＇ physical quality is of great significance to promote the students comprehensive ***, some private colleges and universities sports teaching situation is not very *** paper analyzes the current situation of Public physical Education Teaching of private higher education in Jiangxi Province,and puts forward the corresponding reform and innovation strategy.

关键词： Jiangxi Province Some Private Institutions of Higher Learning physical Education Teaching

Enhanced angiogenesis in porous poly(ε-caprolactone) scaffolds fortified with methacrylated hyaluronic acid hydrogel after subcutaneous transplantation

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Biomaterials Translational 2024年第1期5卷 59-68页

作者： Yang H. Zheng M. Zhang Y. Li C. Lai J.H.C. Zhang Q. Chan K.W.Y. Wang H. Zhao X. Yang Z. Xu C. department of Biomedical Engineering City University of Hong Kong Hong Kong Center for Pluripotent Stem Cell Research and Engineering Research Institute of Tsinghua Guangdong Province Guangzhou China department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Hong Kong

A composite scaffold composed of a porous scaffold and hydrogel filling can facilitate engraftment, survival, and retention in cell transplantation processes. This study presents a composite scaffold made of poly(ε-caprolactone) (PCL) and methacrylated hyaluronic acid (MeHA) hydrogel and describes the corresponding physical properties (surface area, porosity, and mechanical strength) and host response (angiogenesis and fibrosis) after subcutaneous transplantation. Specifically, we synthesise MeHA with different degrees of substitution and fabricate a PCL scaffold with different porosities. Subsequently, we construct a series of PCL/MeHA composite scaffolds by combining these hydrogels and scaffolds. In experiments with mice, the scaffold composed of 3% PCL and 10–100 kDa, degree of substitution 70% MeHA results in the least fibrosis and a higher degree of angiogenesis. This study highlights the potential of PCL/MeHA composite scaffolds for subcutaneous cell transplantation, given their desirable physical properties and host response. © 2024, Chinese Medical Multimedia Press Co Ltd. All rights reserved.

关键词： angiogenesis cell transplantation hyaluronic acid poly(ε-caprolactone) scaffold