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Home quarantine compliance is low in children with fever during COVID-19 epidemic

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World Journal of Clinical Cases 2020年第16期8卷 3465-3473页

作者： Qing Lou De-Quan su sun-Qin Wang E Gao Lian-Qiao Li Zhi-Qiang Zhuo department of emergency Medicine Xiamen Children’s HospitalXiamen 361006Fujian ProvinceChina department of Infections Xiamen Children’s HospitalXiamen 361006Fujian ProvinceChina

BACKGROUND The coronavirus disease 2019(COVID-19)outbreak began in China at the end of *** disease is highly *** order to prevent and control the epidemic situation,the state has issued a series of measures to guide the prevention and control of the *** the same time,it also introduced the measure of home isolation for children with ***,due to the nature of children,the implementation of the home isolation turned out to be quite difficult,and questions regarding the home isolation were brought out by parents when seeing *** this reason,we decided to conduct this *** To study factors that influence home quarantine compliance in children with fever during the COVID-19 *** A total of 495 paediatric patients with respiratory tract infection and fever were selected from the general fever clinic at Xiamen children’s hospital from February 6-27,*** day 8 after the hospital visit,follow-up was conducted by telephone to evaluate the compliance of home *** Among the ten quarantine measures,the proportion of families adhering to keeping 1.5 m distance,proper hand hygiene,wearing masks at home,and proper cough etiquette was very low(sure).Our analysis showed that compliance was related to gender and age of children,gender and age of primary caregiver,number of children in the family,and intensity of information on quarantine *** observed that compliance increased with the age *** with children whose caregivers were young adults,children with elderly caregivers were 2.461 times more likely to show poor ***,children who received intensive information on quarantine measures had significantly better *** Compliance of children with fever to quarantine measures at home is low during the COVID-19 *** education on the quarantine measures is critical to improve compliance,in particular in young children with elderl

关键词： COVID-19 Fever children Home quarantine Compliance Influence factor

West syndrome secondary to Biotinidase Deficiency about a Case

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Neuroscience & Medicine 2017年第3期8卷 29-32页

作者： Madiha Abouelarais Nour Mekaoui Fatima Zohra Oudghiri Khaoula Mammad Lamia Karboubi Badr sououd Benjelloun Dakhama Pediatric medical emergency department Rabat Children’s Hospital University Hospital of Ibn Sina Faculty of Medicine and Pharmacy Mohammed V University Rabat Morocco Unit of Neuroscience and Applied Nutrition Laboratory of Nutrition Health and Environment Department of Biology Faculty of Science Kenitra Morocco

Biotinidase deficiency is an abnormality of biotin metabolism which is manifested by neurological, cutaneous, ophthalmological and auditory signs. It has been described as a cause of West syndrome, but there are few observations that report an association between these latter two. We report the observation of an 18-month old infant born from a first-degree consanguineous marriage, followed since the age of 2 months and half for West syndrome associated with alopecia, also an eczema and deafness in whom the etiological investigation was in favor of a biotinidase deficiency. Thus treatment with biotin resulted in a marked clinical improvement.

关键词： West syndrome secondary One Case Biotinidase Defiency

Information technology and artificial intelligence support in management experiences of the pediatric designated hospital during the COVID-19 epidemic in 2022 in shanghai

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Intelligent Medicine 2023年第1期3卷 16-21页

作者： Yu shi Jin Fu Mei Zeng Yanling Ge Xiangshi Wang Aimei Xia Weijie shen Jiali Wang Weiming Chen siyuan Jiang Xiaowen Zhai department of medical Affairs Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China department of Infectious Diseases Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China department of Critical Care Medicine Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China Outpatient and emergency Management Office Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China department of Neonatology Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China department of Hematology Children’s Medical Center Children’s Hospital of Fudan UniversityShanghai 201102China

Objective:To describe the information technology and artificial intelligence support in management experiences of the pediatric designated hospital in the wave of COVID-19 in ***:We retrospectively concluded the management experiences at the largest pediatric designated hospital from March 1st to May 11th in 2022 in *** summarized the application of Internet hospital,face recognition technology in outpatient department,critical illness warning system and remote consultation system in the ward and the structed electronic medical record in the inpatient *** illustrated the role of the information system through the number and prognosis of patients ***:The COVID-19 designated hospitals were built particularly for critical patients requiring high-level medical care,responded quickly and scientifically to prevent and control the epidemic *** March 1st to May 11th,2022,we received and treated 768 children confirmed by positive RT-PCR and treated at our *** our management,we use Internet Information on the Internet hospital,face recognition technology in outpatient department,critical illness warning system and remote consultation system in the ward,structed electronic medical record in the inpatient *** deaths or nosocomial infections *** number of offline outpatient visits dropped,from March to May 2022,146,106,48,379,57,686 *** the outpatient volume on the internet hospital increased significantly(3,347 in March 2022 vs.372 in March 2021;4,465 in April 2022 vs.409 in April 2021;4,677 in May 2022 vs.538 in May 2021).Conclusions:Information technology and artificial intelligence has provided significant supports in the *** system might optimize the admission screening process,increases the communication inside and outside the ward,achieves early detection and diagnosis,timely isolates patients,and timely treatment of various types of children.

关键词： Coronavirus disease2019 Information technology Artificial intelligence Closed-loop management Pediatric designated hospital

Global Pediatric Pulmonology Alliance recommendation to strengthen prevention of pediatric seasonal influenza under COVID-19 pandemic

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World Journal of Pediatrics 2020年第5期16卷 433-437页

作者： Kun-Ling shen Leyla Namazova-Baranova Yong-Hong Yang Gary Wing Kin Wong Lanny J.Rosenwasser Lance E.Rodewald Anne Eng Neo Goh Eitan Kerem Chris O'Callaghan T.Bernard Kinane Basil Elnazir Rina Triasih Rosemary Horne Anne B Chang Jim Buttery Ruth A.Etzel Kazunobu Ouchi Hilary Hoey Varinder singh Genesis C.Rivera spencer sLi Yu Guan Ling Cao Yue-Jie Zheng Lu-Zhao Feng Wu Zhong Zheng-De Xie Bao-Ping Xu Rong-Jun Lin Gen Lu Qiang Qin Chun-Mei Zhu su-Yun Qian Gang Liu Cheng-song Zhao Zhuang Wei Yu-Hong Zhao Global Pediatric Pulmonology Alliance(GPPA)Expert Panel on Infectious Diseases&COVID-19 China National Clinical Research Center of Respiratory Diseases Department of Respiratory Medicine of Beijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijingChina Pediatrics and Child Health Research Institute Central Clinical HospitalRussian Academy of SciencesMoscowRussian Federation department of Respiratory Shenzhen Children's HospitalShenzhenChina Chinese University of Hong Kong Hong Kong SARChina UMKC school of Medicine Kansas CityMOUSA National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina K Women's and children's hospital SingaporeSingapore department of Pediatrics Hadassah Hebrew University Medical CenterJerusalemIsrael UCL Great Ormond street Institute of Child Health and Great Ormond street hospital(GOsH)BRC University College LondonLondonUK Massachusetts General hospital for children BostonMAUSA children's Health Ireland and Trinity College Dublin DublinIreland department of paediatric Faculty of MedicinePublic Health and NursingUniversitas Gadjah Mada/Dr.Sardjito HospitalYogyakartaIndonesia Monash University MelbourneAustralia Queensland children's hospital BrisbaneAustralia Monash children's hospital Menzies School of Health ResearchMelbourneAustralia George Washington University WashingtonDCUSA department of Pediatrics Kawasaki Medical SchoolKurashiki-CityJapan department of Pediatrics University of Dublin Trinity CollegeDublinIreland Lady Hardinge medical College and Assoc Kalawati saran children's hospital New DelhiIndia Center for medical and Allied Health sciences New Era UniversityQuezon Citythe Philippines Global Pediatric Pulmonology Alliance Hong Kong SARChina department of Respiratory the Children's Hospital Affiliated to the Capital Institute of PediatricsBeijingChina school of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina National Engineering Research Center for the emergency Drug BeijingChina Nati

The World Health Organization(WHO)announced COVID-19 as a global pandemic in March of 2020[1].The COVID-19 pandemic may persist for a long period of *** prevention and control becomes a complex and challenging task,and such efforts should be *** general measures,such as social distancing,face masks,respiratory hygiene and hand sanitization,will bear fruits for decreasing spread of other respiratory illnesses including influenza,the specific prevention through vaccination is a key focus especially in the upcoming winter and spring seasons[2].

关键词： prevention influenza sustained

systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis

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World Journal of Gastrointestinal surgery 2024年第8期16卷 2565-2573页

作者： Li-Ming Guo Zhi-Hui Jiang Hong-Zhen Liu department of General surgery Qingdao Women and Children’s HospitalQingdao 266000Shandong ProvinceChina department of Pediatric surgery Children's Hospital Affiliated to Shandong UniversityJinan 250022Shandong ProvinceChina department of Pediatric surgery Jinan Children's HospitalJinan 250022Shandong ProvinceChina

BACKGROUND Pediatric appendicitis is a common cause of abdominal pain in children and is recognized as a significant surgical emergency.A prompt and accurate diagnosis is essential to prevent complications such as perforation and *** To investigate the predictive value of the systemic immune-inflammation index(sII)combined with the pediatric appendicitis score(PAs)for the assessment of disease severity and surgical outcomes in children aged 5 years and older with *** Clinical data of 104 children diagnosed with acute appendicitis were *** participants were categorized into the acute appendicitis group and chronic appendicitis group based on disease presentation and further stratified into the good prognosis group and poor prognosis group based on *** sII and PAs were measured,and a joint model using the combined sII and PAs was constructed to predict disease severity and surgical *** significant differences were observed in the sII and PAs parameters between the acute appendicitis group and chronic appendicitis *** analysis showed associations among the sII,PAs,and disease severity,with the combined sII and PAs model demonstrating significant predictive value for assessing disease severity[aera under the curve(AUC)=0.914]and predicting surgical outcomes(AUC=0.857)in children aged 5 years and older with *** The study findings support the potential of integrating the sII with the PAs for assessing disease severity and predicting surgical outcomes in pediatric appendicitis,indicating the clinical utility of the combined sII and PAs model in guiding clinical decision-making and optimizing surgical management strategies for pediatric patients with appendicitis.

关键词： systemic immune-inflammation index Pediatric appendicitis score Disease severity surgical outcomes Risk factor Logistic regression Receiver operating characteristic analysis

Neurofibromatosis Type 1 in Four children Cases

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Neuroscience & Medicine 2017年第3期8卷 33-40页

作者： C. Mammad N. Mekaoui F. Z. Ouadghiri K. Mammad B. s. Benjeloun Dakhama Pediatric medical emergency department Rabat Children’s Hospital University Hospital of IbnSina Faculty of Medicine and Pharmacy Mohammed V University Rabat Morocco Unit of Neuroscience and Applied Nutrition Laboratory of Nutrition Health and Environment Department of Biology Faculty of Science Kenitra Morocco

Neurofibromatosis Type 1 (NF-1 or Von Recklinghausen disease) is an autosomal dominant genetic disease, characterized by an extreme variability of its clinical expression which is also found in the same family. Our work focuses on the exploitation of four cases of patients with NF-1 who were enrolled in the paediatric neurology consultation at rabat children’s hospital. They are two infants and two children. Otherwise the diagnosis was made in front of the existence of café au lait and lentiginous spots in two boys, also the existence of café au lait spots and abnormalities in brain imaging in two girls. Thus an evolution was marked by a favorable outcome for three patients and neurological sequelae in one patient.

关键词： Neurofibromatosis Type 1 children Café au lait spots Lentiginous

The clinical and immunological features of pediatric COVID-19 patients in China

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Genes & Diseases 2020年第4期7卷 535-541页

作者： Juan Chen Zhen-Zhen Zhang Yao-Kai Chen Quan-Xin Long Wen-Guang Tian Hai-Jun Deng Jie-Li Hu Xian-Xiang Zhang Pu-Liao Jiang-Lin Xiang Dao-Xin Wang Peng Hu Fa-Chun Zhou Zhi-Jie Li Hong-Mei Xu Xue-Fei Cai De-Qiang Wang Yuan Hu Ni Tang Bei-Zhong Liu Gui-Cheng Wu Ai-Long Huang The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education Department of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqingChina department of Infectious Diseases National Clinical Research Center for Child Health and DisordersThe Children’s Hospital of Chongqing Medical UniversityChongqingChina Division of Infectious Diseases Chonqging Public Health Medical CenterChongqingChina department of Infectious Diseases Yongchuan Hospital Affiliated to Chongqing Medical UniversityChongqingChina department of Endocrinology Chongqing Three Gorges Central HospitalChongqingChina department of Clinical Laboratory Chongqing People’s HospitalChongqingChina department of Infectious Diseases Chongqing Three Gorges Central HospitalChongqingChina department of Respiration The First Affiliated HospitalChongqing Medical UniversityChongqingChina department of emergency The First Affiliated HospitalChongqing Medical UniversityChongqingChina department of Clinical Laboratory Yongchuan Hospital Affiliated to Chongqing Medical UniversityChongqingChina department of Liver Disease Chongqing Three Gorges Central HospitalChongqingChina

In December 2019,the corona virus disease 2019(COVID-19)caused by novel coronavirus(sARs-CoV-2)emerged in Wuhan,China and rapidly spread *** information on clinical features and immunological profile of COVID-19 in *** clinical features and treatment outcomes of twelve paediatric patients confirmed as COVID-19 were *** immunological features of children patients was investigated and compared with twenty adult *** median age was 14.5-years(range from 0.64 to 17),and six of the patients were *** average incubation period was 8 ***,cough(9/12,75%)and fever(7/12,58.3%)were the most common *** patients(33.3%)had diarrhea during the *** to the immune profile,children had higher amount of total T cell,CD8t T cell and B cell but lower CRP levels than adults(Pss opacity(GGO)and local patchy shadowing were the typical radiological findings on chest CT *** patients received antiviral and symptomatic treatment and the symptom relieved in 3e4 days after admitted to *** paediatric patients showed mild symptom but with longer incubation *** infected with sARs-CoV-2 had different immune profile with higher T cell amount and low inflammatory factors level,which might ascribed to the mild clinical *** advise that nucleic acid test or examination of serum IgM/IgG antibodies against sARs-CoV-2 should be taken for children with exposure history regardless of clinical symptom.

关键词： Clinical features COVID-19 Immune paediatrics sARs-CoV-2

paediatric primary care in Germany during the early COVID-19 pandemic:the calm before the storm

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Family Medicine and Community Health 2021年第2期9卷 40-47页

作者： Malte Kohns Vasconcelos Katharina Weil Daniela Vesterling-Hörner Mehrsad Klemm Tarik el scheich Hanna Renk Katharina Remke Hans Martin Bosse Institute for medical Microbiology and hospital Hygiene Heinrich Heine University DüsseldorfDüsseldorfGermany department for General paediatrics Neonatology and Paediatric CardiologyUniversity Hospital DüsseldorfDüsseldorfGermany paediatric Practice Dr.med.Vesterling-Hörner DüsseldorfGermany Kinderärzte im Karree LeverkusenGermany Kinderärzte am Zoo DüsseldorfGermany department of paediatric Cardiology Pulmonology and Intensive Care MedicineUniversity Children’s Hospital TübingenTübingenGermany

Objectives Globally,the COVID-19 pandemic has a major impact on healthcare *** effects in primary care are *** study aimed to explore changes in consultation numbers and patient management during the COVID-19 pandemic,and to identify challenges for patient *** survey of paediatric primary care practices on consultation numbers and patient management changes,and semistructured interviews to identify challenges for patient *** and interviews were partially linked in an explanatory sequential design to identify patient groups perceived to be at higher risk for worse care during the *** In and around Düsseldorf,a densely populated area in Western *** primary care facilities are spread over an area with approximately 2 million *** Primary care in Germany is provided through practices run by self-employed specialist physicians that are contracted to offer services to patients under public health insurance which is compulsory to the majority of the *** sample contained 44 paediatric primary care practices in the area,the response rate was 50%.Results Numbers of consultations for scheduled developmental examinations remained unchanged compared with the previous year while emergency visits were strongly reduced(mean 87.3 less/week in March-May 2020 compared with 2019,median reduction 55.0%).children dependent on developmental therapy and with chronic health conditions were identified as patient groups receiving deteriorated *** patient numbers,including of mildly symptomatic children presenting for health certificates,in combination with increased organisational demands and expected staff outages are priority concerns for the *** Primary care paediatricians offered stable service through the early pandemic but expected strained resources for the upcoming *** guidance on which children should present to primary care and who should be tested would h

关键词： winter storm unchanged

Epidemiology and incidence of paediatric orthopaedic trauma workload during the COVID-19 pandemic:A multicenter cohort study of 3171 patients

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World Journal of Orthopedics 2022年第1期13卷 70-77页

作者： Morten Kjerri Rasmussen Peter Larsen Jan Duedal Rölfing Bertram Lahn Kirkegaard Rikke Thorninger Rasmus Elsoe department of Orthopaedic surgery Aalborg University HospitalAalborg DK-9000Denmark department of Occupational Therapy and Physiotherapy Aalborg University HospitalAalborg DK-9000Denmark children’s Orthopaedics and Reconstruction Danish Paediatric Orthopaedic ResearchAarhus University HospitalAarhus DK-8200Denmark department of Orthopaedic surgery Regional Hospital RandersRanders 8930Denmark

BACKGROUND Coronavirus disease 2019(COVID-19)has a major influence on all parts of *** To examine the consequences of the national lockdown and political initiatives during the first surge of the COVID-19 pandemic expressed by changes in incidences of musculoskeletal paediatric *** study design was a retrospective multicenter cohort study.A‘pandemic’cohort was established from 16 March 2020 to 21 April 2020,where all institutions including day care and schools were closed.A‘pre-pandemic’cohort was established from the same period in 2019 for *** were all patients admitted at the emergency departments with paediatric musculoskeletal injuries(aged 0-15 years)identified by a relevant musculoskeletal ICD-10 diagnosis(Dsxxx),concussions(DZ033D),or burns(DT2xx).REsULTs The‘pre-pandemic’cohort consisted of 2101 patients,and the‘pandemic’cohort consisted of 1070 patients,indicating a decrease of paediatric musculoskeletal injuries of 51%.The incidence of paediatric injury in the‘pre-pandemic’cohort was 10460/100000/*** the‘pandemic’cohort,the incidence was 5344/100000/*** A resource re-allocation to help serve the COVID-19 patients might be possible without reducing the level of care for injury-related paediatric patients.

关键词： COVID-19 sARs-CoV-2 paediatric trauma paediatric emergency paediatric fracture