检索结果-南通市图书馆

Corneal collagen cross-linking in patients with keratoconus from the Dresden protocol to customized solutions:theoretical basis

引用

International Journal of Ophthalmology(English edition) 2024年第5期17卷 951-962页

作者： Ciro Caruso Luca D’Andrea Mario Troisi Michele Rinaldi Raffaele Piscopo Salvatore Troisi Ciro Costagliola Corneal Transplant Center Pellegrini HospitalVia Portamedina alla Pignasecca 41Napoli 80127Italy Eye Clinic Department of NeurosciencesReproductive and Odontostomatological SciencesUniversity of Naples Federico IINaples 80131Italy Public Health department University of Naples Federico IINaples 80131Italy Salerno Hospital University Ophthalmologic UnitBaronissiCampania 84131Italy

Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual *** therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages,gas-permeable rigid contact lenses,scleral lenses,implantation of intrastromal corneal ring or corneal transplants for most advanced *** keratoconus cases showing disease progression corneal collagen crosslinking(CXL)has been proven to be an effective,minimally invasive and safe *** consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation,resulting in stromal crosslinks *** aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models,from the original Dresden protocol to the most recent developments in the technique,reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment ***,the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted.

关键词： corneal collagen cross linking keratoconus custom fast protocol Dresden protocol lambert-beer law Bunsen-roscoe law

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease:a retrospective single-center experience

引用

Asian Journal of Andrology 2024年第3期26卷 268-271页

作者： Simone Cilio Roberto La Rocca Giuseppe Celentano Claudio Marino Massimiliano Creta Gianluigi Califano Celeste Manfredi Giorgio Ivan Russo Afonso Morgado Marco Falcone Marco Capece YAU Working Group Sexual and reproductive Health department of neurosciences Reproductive Sciences and OdontostomatologyUrology UnitUniversity of Naples“Federico II”Naples 80131Italy Urology Unit Department of WomenChild and General and Specialized Surgery“Luigi Vanvitelli”UniversityNaples 80131Italy Urology Section Department of SurgeryUniversityof CataniaCatania 95131Italy department of Urology Centro Hospitalar Universitário São JoãoPorto 4200-319Portugal Urology Clinic-A.O.U.“Cittàdella Salute edella Scienza”-Molinette Hospital University of TurinTurin 10100Italy 不详

Peyronie’s disease(PD)is a condition of penile connective tissue affecting up to 10%of men *** the complexity ofits management,nonsurgical treatments,such as intraplaque injections,are gaining *** current literature shows dataon the efficacy of intraplaque injections of hyaluronic acid(HA)mainly in acute-phase ***,data on injections of HA instable-phase PD are *** for this retrospective study were derived from a prospectively maintained database of privatepatients presenting at a private medical practice affiliated to the University of Naples“Federico II”(Naples,Italy)with stable-phasePD between January 2020 and March *** underwent a standard protocol of three injections,each administered at atwo-week *** the intervals,patients performed vacuum device therapy,penile stretching,and modeling *** compiled the Peyronie’s Disease Questionnaire(PDQ)and Global Assessment of Peyronie’s Disease(GAPD)at baselineand 2 weeks after the third injection.A penile Doppler ultrasound was performed 2 weeks after the last injection to record thefinal ***,we recruited 62 patients with stable-phase PD and a mean(±standard deviation[s.d.])curvature of52.7°(±9.7°).After 6 weeks,eight(12.9%)patients did not experience any curvature *** remaining 54 patientshad a final mean(±s.d.)curvature of 40.3°(±9.1°)with P<0.001,compared to that before *** found improvement inall PDQ domains(all P≤0.01),and 50(80.6%)patients reported subjective improvement of the penile curvature according to *** conclusion,we demonstrated that after three injections of HA administered according to the adopted protocol,patientswith stable-phase PD could experience significant improvements in penile curvature,and physical and psychological consequencesof the disease without significantly relevant side effects.

关键词： hyaluronic acid intraplaque injection Peyronie’s disease stable-phase therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Emerging role of lysosomal calcium store as a hub of neuroprotection

引用

Neural Regeneration Research 2022年第6期17卷 1259-1260页

作者： Valentina Tedeschi Agnese Secondo Division of Pharmacology Department of NeuroscienceReproductive and Odontostomatological SciencesSchool of Medicine“Federico II”University of NaplesNaplesItaly

Filled with more than 60 different types of hydrolases,the acidic organelle lysosome governs cellular digestion by removing damaged organelles and catabolic products(Xu and Ren,2015).Beyond the canonical role in the intracellular degradative pathways,lysosome precedes nutrient sensing,autophagy,immune cell signaling,metabolism and membrane repair.

关键词： metabolism removing store

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR):A critical overview on the most promising applications of molecular scissors in oral medicine

引用

BIOCELL 2022年第8期46卷 1837-1842页

作者： MARCO TATULLO LUISA LIMONGELLI ROSA MARIA MARANO ALESSANDRA VALLETTA ANGELA TEMPESTA SANDRO RENGO department of Basic Medical sciences Neurosciences and Sense OrgansUniversity of Bari Aldo MoroBari74124Italy department of Interdisciplinary Medicine University of Bari Aldo MoroBari74124Italy Marrelli Health-Tecnologica Research Institute Biomedical SectionStem Cells and Medical Genetics UnitsCrotone88900Italy department of neurosciences Reproductive and Odontostomatological SciencesUniversity of Naples Federico IINaples80131Italy

The scientific community is continuously working to translate the novel biomedical techniques into effective medical ***-Cas9 system(Clustered Regularly Interspaced Short Palindromic Repeats-9),commonly known as the“molecular scissor”,represents a recently developed biotechnology able to improve the quality and the efficacy of traditional treatments,related to several human diseases,such as chronic diseases,neurodegenerative pathologies and,interestingly,oral *** course,dental medicine has notably increased the use of biotechnologies to ensure modern and conservative approaches:in this landscape,the use of CRISPR-Cas9 system may speed and personalize the traditional therapies,ensuring a good predictability of clinical *** aim of this critical overview is to provide evidence on CRISPR efficacy,taking into specific account its applications in oral medicine.

关键词： Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR) Dentistry Stem cells

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural compounds may contribute in preventing SARS-CoV-2 infection:a narrative review

引用

Food Science and Human Wellness 2022年第5期11卷 1134-1142页

作者： Maria Eleonora Bizzoca Stefania Leuci Michele Davide Mignogna Eleonora Lo Muzio Vito Carlo Alberto Caponio Lorenzo Lo Muzio department of Clinical and Experimental Medicine University of FoggiaFoggia 71122Italy department of neurosciences Reproductive and Odontostomatological SciencesFederico Ⅱ University of NaplesNaples 80131Italy department of Neuroscience and Rehabilitation University of FerraraFerrara 44121Italy C.I.N.B.O.(Consorzio Interuniversitario Nazionale per la Bio-Oncologia) Chieti 66100Italy

Coronavirus pandemic infection is the most important health issue *** disease 2019 is a contagious disease characterized by severe acute respiratory syndrome coronavirus *** date,excluding the possibility of vaccination,against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient’s *** industry is investigating effects of medicinal plants,phytochemical extracts and aromatic herbs to find out natural substances which may act as antiviral *** studies have revealed how these substances may interfere with the viral life cycle,viral entry,replication,assembly or discharge,as well as virus-specific host targets or stimulating the host immune system,reducing oxidative stress and inflammatory response.A natural compound can be used as a prophylaxis by people professionally exposed to the risk of contagion and/or positive patients not in intensive *** aim of this paper is to perform a narrative review of current literature in order to summarize the most studied natural compounds and their modes of action.

关键词： Natural compounds SARS-CoV-2 COVID-19 Prevention Infectious disease Phytochemicals Medicinal plants

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Orbital metastases in Italy

引用

International Journal of Ophthalmology(English edition) 2015年第5期8卷 1018-1023页

作者： Patrizio Magliozzi Diego Strianese Paola Bonavolontà Mariantonia Ferrara Pasquale Ruggiero Raffaella Carandente Giulio Bonavolontà Fausto Tranfa department of Neuroscience Odontostomatological and Reproductive SciencesUniversity of Naples Federico Ⅱ

AIMTo describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of *** chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of *** of 93 patients, 52 were females and 41 were males. Median age at diagnosis was 51y (range 1 to 88y). The patients have been divided into four groups on the basis of the year of diagnosis. The frequency of recorded cases had decreased significantly (P<0.05) during the last 9.5y. Primary tumor site was breast in 36 cases (39%), kidney in 10 (11%), lung in 8 (9%), skin in 6 (6%); other sites were less frequent. In 16 case (17%) the primary tumor remained unknown. The most frequent clinical findings were proptosis (73%), limited ocular motility (55%), blepharoptosis (46%) and blurred vision (43%). The diagnosis were established by history, ocular and systemic evaluation, orbital imaging studies and open biopsy or fine needle aspiration biopsy (FNAB). Treatment included surgical excision, irradiation, chemotherapy, hormone therapy, or observation. Ninety-one percent of patients died of metastasis with an overall mean survival time (OMST) after the orbital diagnosis of ***, kidney and lung are the most frequent primary sites of cancer leading to an orbital metastasis. When the primary site is unknown, gastrointestinal tract should be carefully investigated. In the last decade a decrease in the frequency of orbital metastasis has been observed. Surgery provides a local palliation. Prognosis remains poor with a OMST of 13.5mo ranging from the 3mo in the lung cancer to 24mo in the kidney tumor.

关键词： orbital metastasis primary tumor survival time

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical and prostate multiparametric magnetic resonance imaging findings as predictors of general and clinically significant prostate cancer risk:A retrospective single-center study

引用

Current Urology 2023年第3期17卷 147-152页

作者： Matteo Massanova Rebecca Vere Sophie Robertson Felice Crocetto Biagio Barone Lorenzo Dutto Imran Ahmad Mark Underwood Jonathan Salmond Amit Patel Giuseppe Celentano Jaimin R.Bhatt department of Urology Queen Elizabeth University HospitalGlasgowUK department of Neuroscience Reproductive and Odontostomatological SciencesSchool of MedicineUniversity of Naples"FedericoⅡ"NaplesItaly department of Pathology Queen Elizabeth University HospitalGlasgowUK department of Radiology Queen Elizabeth University HospitalGlasgowUK

Background:To evaluate the predictive values of Prostate Imaging Reporting and Data System version 2(PI-RADS v2),prostate-specific antigen(PSA)level,PSA density(PSAD),digital rectal examination findings,and prostate volume,individually and in combination,for the detection of prostate cancer(Pca)in biopsy-naïve ***:We retrospectively analyzed 630 patients who underwent transrectal systematic prostate biopsy following prostate multiparametric magnetic resonance imaging.A standard 12-core biopsy procedure was *** and multivariate analyses were performed to determine the significant predictors of clinically significant cancer but not ***:The median age,PSA level,and PSAD were 70 years,8.6 ng/mL,and 0.18 ng/mL/mL,respectively.A total of 374(59.4%)of 630 patients were biopsy-positive for Pca,and 241(64.4%)of 374 were diagnosed with clinically significant Pca(csPCa).The PI-RADS v2 score and PSAD were independent predictors of Pca and *** PI-RADS v2 score of 5 regardless of the PSAD value,or PI-RADS v2 score of 4 plus a PSAD of<0.3 ng/mL/mL,was associated with the highest csPCa detection rate(36.1%-82.1%).Instead,the PI-RADS v2 score of<3 and PSAD of<0.3 ng/mL/mL yielded the lowest risk of ***:The combination of the PI-RADS v2 score and PSAD could prove to be a helpful and reliable diagnostic tool before performing prostate *** with a PI-RADS v2 score of<3 and PSAD of<0.3 ng/mL/mL could potentially avoid a prostate biopsy.

关键词： Prostate cancer Prostate Imaging Reporting and Data System score Multiparametric magnetic resonance imaging Transrectal ultrasound Prostate biopsy Prostate-specific antigen density

来源：评论

学校读者我要写书评

暂无评论

Association between Epilepsy and Psychogenic Non-Epileptic Seizures: A Case Report

引用

Open Journal of Psychiatry 2017年第1期7卷 40-50页

作者： Diana Galletta Monica Confuorto Ilaria Lauria Valentina Suarato Annamaria Califano Anna Maria Mastrola Fausta Micanti department of neurosciences and reproductive and odontostomatological sciences University of Naples Federico II Naples Italy

Epilepsy is a very complex disorder of the central nervous system. It is characterized by a sudden, disordered and excessive neuronal shock that causes different clinical evidences with specific related electroencephalogram (EEG). Psychogenic Non-Epileptic Seizures (PNES) can seriously complicate the diagnosis of epilepsy. The separoxysmal events have the same clinical evidences of epilepsy, such as an impairment of the self-control and a range of sensory, motor and mental manifestations, without the typical related electroencephalogram (EEG) because of the absence of an organic cause. The overwhelming majority of Psychogenic Non-Epileptic Seizures are related to psychological factors like dissociation. This is a defense mechanism used to cope stressful events or emotional conflicts. Psychological or psychiatric disorders, like Post Traumatic Stress Disorder (PTSD), are frequently associated to Psychogenic Non-Epileptic Seizures. In this article, we present a case report of epilepsy combined with Psychogenic Non-Epileptic Seizures. A joint intervention is of great significance in this occurrence. The subject received a psychological assessment including psychometric and projective tools. He stood MMPI-2, Wais-R, SCL-90, Rorschach test and graphic tests. A psychological disorder related to defense mechanisms was identified. The subject presents a tendency to convert his fears and emotive pains in rational and more socially acceptable problems, using his body to express his discomfort. Patient with epileptic seizures should receive a psychological assessment to exclude Psychogenic Non-Epileptic Seizures. Further studies should propose guidelines to integrate neurological, psychiatric and psychological intervention.

关键词： Epilepsy Psychogenic Non-Epileptic Seizures PNES Dissociation PTSD

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiological and clinical aspects of hepatitis B virus infection in Italy over the last 50 years

引用

World Journal of Gastroenterology 2022年第26期28卷 3081-3091页

作者： Caterina Sagnelli Antonello Sica Massimiliano Creta Armando Calogero Massimo Ciccozzi Evangelista Sagnelli department of Mental Health and Public Medicine Section of Infectious DiseasesUniversity of Campania“Luigi Vanvitelli”Naples 80138Italy department of Precision Medicine University of Campania“Luigi Vanvitelli”Naples 80131Italy department of neurosciences Reproductive Sciences and OdontostomatologyUniversity of Naples Federico IINaples 80138Italy department of Advanced Biomedical sciences-UO General Surgery University Federico II of NaplesNaples 80127Italy Medical Statistics and Molecular Epidemiology Unit Campus Bio-Medico UniversityRome 80138Italy

A relevant gradual reduction of both the incidence rate of acute hepatitis B(AHB)and prevalence of chronic hepatitis B has occurred in Italy in the last 50 years,due to substantial epidemiological changes:Improvement in socioeconomic and hygienic conditions,reduction of the family unit,accurate screening of blood donations,abolition of re-usable glass syringes,hepatitis B virus(HBV)-universal vaccination started in 1991,use of effective well tolerated nucleo(t)side analogues able to suppress HBV replication available from 1998,and educational mediatic campaigns against human immunodeficiency virus infection focusing on the prevention of sexual and parenteral transmission of *** an example,AHB incidence has gradually decreased from 10/100000 inhabitants in 1985 to 0.21 in ***,the coronavirus disease 2019(COVID-19)pandemic has interrupted the trend towards HBV *** fact,several HBV chronic carriers living in the countryside have become unable to access healthcare facilities for screening,diagnosis,clinical management,and nucleo(t)side analogue therapy in the COVID-19 pandemic,mainly for anxiety of becoming infected with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),movement restrictions,and reduced gains from job *** addition,one-third of healthcare facilities and personnel for HBV patients have been devolved to the COVID-19 assistance.

关键词： Hepatitis B virus Hepatitis B virus epidemiology Acute hepatitis B COVID-19

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optical coherence tomography angiography in incomplete acute Vogt-Koyanagi-Harada disease

引用

International Journal of Ophthalmology(English edition) 2017年第4期10卷 661-662页

作者： gilda cennamo mario r.romano claudio iovino giuseppe de crecchio giovanni cennamo Eye Clinic Department of Neurosciences Reproductive Sciences and Dentistry University of Naples Federico ⅡNaples 80100 Italy

Dear Editor,Vogt-Koyanagi-Harada（VKH）disease is a cell-mediated autoimmune syndrome directed against *** is considered a multisystem disorder characterized by granulomatous panuveitis often associated with neurologi... 详细信息

关键词： area Figure Optical coherence tomography angiography in incomplete acute Vogt-Koyanagi-Harada disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：