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Rapid assessment checklist for green roof ecosystem services in Bangkok,Thailand

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Ecological Processes 2020年第1期9卷 205-221页

作者： Rattanapan Phoomirat Nipada Ruankaew Disyatat Tae Yoon Park Dong Kun Lee Pongchai Dumrongrojwatthana Biological Sciences Program Faculty of ScienceChulalongkorn UniversityBangkok 10330Thailand department of Biology Faculty of ScienceChulalongkorn UniversityBangkok 10330Thailand Graduate School of Education Yonsei UniversitySeoul 03722Republic of Korea department of landscape architecture and rural system engineering Seoul National UniversitySeoul 08826Republic of Korea

Background:A green roof is a man-made ecosystem created when a rooftop is covered with substrate and *** green roof ecosystems(GREs)are able to provide ecosystem services,there is currently no assessment tool available to specifically evaluate ***,the aim of this study was to develop a rapid assessment checklist(RAC)to assess GRE services(GRES),which was developed and tested on 10 green roofs in Bangkok,***:The RAC consisted of 46 proxy indicators(33 qualitative and 13 quantitative indicators)encompassing various aspects of *** GRES values or scores varied according to structural differences in the green *** average score(from a maximum of 100)of total ecosystem services was 61±7,which could be inferred as a good performance in ecosystem service *** highest scores were obtained from the regulating services at 68±*** lowest average score was 53±11 from the provisioning ***:The RAC was able to evaluate the levels of GRES provided by the selected green roofs,enabling the meaningful comparison of their potential capability to provide ***,this RAC could be an innovative tool for evaluation of four categories of GRES.

关键词： Vegetated roof Evaluation Composite indicator Urban ecosystem Ecosystem management

Contradiction and consistency:Deconstruction of landscape bridges based on multiple temporal-spatial scales

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Frontiers of Architectural Research 2022年第1期11卷 53-72页

作者： Haifei Zhou Edoardo Currà Jiawei Leng Yu Xu Wenkang Hu department of architecture Southeast UniversityNanjingChina department of Civil Building and Environmental EngineeringSapienza University of RomeRomeItaly department of architecture Sapienza University of RomeRomeItaly

This study explores the essential issues pertaining to a landscape bridge based on a multi-scale methodology,in view of the paucity of design theories for contemporary landscape *** contribute to reinterpret landscape bridges on their physical temporal-spatial scales,instead of from perspectives of individual disciplines or their mechanical *** in a new systematized framework,we elaborate the dominant and their opposite counterparts of landscape bridges from a binary deconstruction point of view,i.e.,(1)Development and retrogression on the temporal scale,(2)connection and separation on the spatial topographic scale,(3)skyphilia and topophilia on the spatial landscape scale,and(4)extroversion and introversion on the spatial architectural *** deconstructed multifaceted scales are instrumental in understanding landscape bridges from various perspectives,with a pyramid model proposed afterward to mediate the discovered oppositions and stimulate the cross-scale *** possible design paths could be derived from this well-organized and openminded multiple system,which is initially expected in this study to inspire bridge designers with dissimilar backgrounds and calls for a wider ramification.

关键词： landscape bridges Bridge design theory Deconstruction Temporal-spatial scales Multi-scale integration

Interplay between the glymphatic system and neurotoxic proteins in Parkinson’s disease and related disorders:current knowledge and future directions

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Neural Regeneration Research 2024年第9期19卷 1973-1980页

作者： Yumei Yue Xiaodan Zhang Wen Lv Hsin-Yi Lai Ting Shen department of Neurology of Sir Run Run Shaw Hospital Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang ProvinceChina department of Emergency Medicine The University of Hong KongHong Kong Special Administrative RegionChina department of Neurology of the Second Affiliated Hospital and School of Brain Science and Brain Medicine Interdisciplinary Institute of Neuroscience and TechnologyKey Laboratory of Medical Neurobiology of Zhejiang ProvinceZhejiang University School of MedicineHangzhouZhejiang ProvinceChina College of Biomedical engineering and Instrument Science Zhejiang UniversityHangzhouZhejiang ProvinceChina MOE Frontier Science Center for Brain Science and Brain-Machine Integration State Key Laboratory of Brain-machine IntelligenceSchool of Brain Science and Brain MedicineZhejiang UniversityHangzhouZhejiang ProvinceChina

Parkinson’s disease is a common neurodegenerative disorder that is associated with abnormal aggregation and accumulation of neurotoxic proteins,includingα-synuclein,amyloid-β,and tau,in addition to the impaired elimination of these neurotoxic *** parkinsonism,which has the same clinical presentation and neuropathology as Parkinson’s disease,expands the disease landscape within the continuum of Parkinson’s disease and related *** glymphatic system is a waste clearance system in the brain,which is responsible for eliminating the neurotoxic proteins from the interstitial *** of the glymphatic system has been proposed as a significant contributor to the development and progression of neurodegenerative disease,as it exacerbates the aggregation of neurotoxic proteins and deteriorates neuronal ***,impairment of the glymphatic system could be considered as the final common pathway to *** evidence has provided initial insights into the potential effect of the impaired glymphatic system on Parkinson’s disease and related disorders;however,many unanswered questions *** review aims to provide a comprehensive summary of the growing literature on the glymphatic system in Parkinson’s disease and related *** focus of this review is on identifying the manifestations and mechanisms of interplay between the glymphatic system and neurotoxic proteins,including loss of polarization of aquaporin-4 in astrocytic endfeet,sleep and circadian rhythms,neuroinflammation,astrogliosis,and *** review further delves into the underlying pathophysiology of the glymphatic system in Parkinson’s disease and related disorders,and the potential implications of targeting the glymphatic system as a novel and promising therapeutic strategy.

关键词： atypical parkinsonism glymphatic system magnetic resonance imaging neurotoxic proteins Parkinson’s disease

Evolving landscape of treatments targeting the microenvironment of liver metastases in non-small cell lung cancer

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Chinese Medical Journal 2024年第9期137卷 1019-1032页

作者： Lingling Zhu Xianzhe Yu Xiaojun Tang Chenggong Hu Lei Wu Yanyang Liu Qinghua Zhou Lung Cancer Center Lung Cancer InstituteWest China HospitalSichuan UniversityChengduSichuan 610041China Key Laboratory of Drug Targeting and Drug Delivery systems Ministry of EducationWest China School of PharmacyCollege of Polymer Science and EngineeringSichuan UniversityChengduSichuan 610041China department of Gastrointestinal Surgery Chengdu Second People’s HospitalChengduSichuan 610041China department of Critical Care Medicine West China HospitalSichuan UniversityChengduSichuan 610041China Core Facility of West China Hospital Sichuan UniversityChengduSichuan 610041China department of Medical Oncology Cancer CenterWest China HospitalSichuan UniversityChengduSichuan 610041China

Liver metastases(LMs)are common in lung *** substantial advances in diagnosis and treatment,the survival rate of patients with LM remains low as the immune-suppressive microenvironment of the liver allows tumor cells to evade the immune *** impact of LMs on the outcomes of immune checkpoint inhibitors in patients with solid tumors has been the main focus of recent translational and clinical *** evidence indicates that the hepatic microenvironment delivers paracrine and autocrine signals from non-parenchymal and parenchymal ***,these microenvironments create pre-and post-metastatic conditions for the progression of ***,we reviewed the epidemiology,physiology,pathology and immunology,of LMs associated with non-small cell lung cancer and the role and potential targets of the liver microenvironment in LM in each phase of ***,we reviewed the current treatment strategies and challenges that should be overcome in preclinical and clinical *** approaches target liver elements as the basis for future clinical trials,including combinatorial interventions reported to resolve hepatic immune suppression,such as immunotherapy plus chemotherapy,immunotherapy plus radiotherapy,immunotherapy plus anti-angiogenesis therapy,and surgical resection.

关键词： Non-small cell lung cancer Liver metastasis Combination therapy Immune checkpoint inhibitors Immune tolerance Immunotherapy

Genotype Screening of Recipient Resources with High Regeneration and Transformation Efficiency in Chrysanthemum

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Phyton-International Journal of Experimental Botany 2022年第4期91卷 869-888页

作者： Yajun Li Yumeng Cui Bingjie Wang Yue Li Mengmeng Zhang Silan Dai He Huang Beijing Advanced Innovation Center for Tree Breeding by Molecular Design Beijing Key Laboratory of Ornamental Plants Germplasm Innovation&Molecular BreedingNational Engineering Research Center for FloricultureBeijing Laboratory of Urban and Rural Ecological EnvironmentKey Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of EducationMinistrySchool of Landscape ArchitectureBeijing Forestry UniversityBeijing100083China Beijing Botanical Garden Beijing100093China

Genetic transformation is one of the key steps in the molecular breeding of chrysanthemum,which relies on an optimal regeneration and transformation ***,the regeneration system of different chrysanthemum cultivars varies,and the regeneration time of most cultivars is *** screen cultivars with highly efficient regeneration,leaves and shoot tip thin cell layers(tTCL)from eight chrysanthemum cultivars with different flower colors and flower types were cultured on Murashige and Skoog media(MS)supplemented with 1.0-5.0 mg L^(−1)6-benzylaminopurine(6-BA)and 0.1-1.0 mg L^(−1)α-naphthaleneacetic(NAA).The results showed that the most efficient regeneration media were MS+6-BA 1.0 mg L^(−1)+NAA 0.5 mg L^(−1)for leaf explants and MS+6-BA 5.0 mg L^(−1)+NAA 0.1 mg L^(−1)for tTCL ***,another 13 chrysanthemum cultivars were screened by using the media,and finally,three cultivars with high regeneration efficiency were obtained from 21 *** these,C1 had the highest regeneration efficiency:the regeneration rate of leaf explants reached 80.0%after 42 days of culture,and the regeneration rate of tTCL explants reached 100%after 31 days of ***,we also established the transformation system for C1 as follows:preculturing for one day,infecting with Agrobacterium suspension(OD_(600)=0.6)for 10 min,and cultivating in the regeneration medium with 350 mg L^(−1)carbenicillin and 10 mg L^(−1)kanamycin,thus ultimately achieving a transformation rate of 4.0%.In this study,a new chrysanthemum cultivar with an efficient regeneration and transformation system was screened,which is beneficial to enrich the flower color of chrysanthemum transgenic plant recipients and to the functional research of flower color or type-related genes.

关键词： Chrysanthemum tissue culture regeneration system genetic transformation cultivars screening

Constructing a Practice-Oriented Education system of Urban-rural Planning

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China City Planning Review 2015年第3期24卷 30-35页

作者： Yin Jie Luo Xiaolong Zhang Qingfei department of Urban and rural Planning College of Landscape ArchitectureNanjing Forestry University School of architecture and Urban Planning Nanjing University

As China's urbanization accelerates, there is an increasing demand for urban-rural planning at both national and local levels, making it become an independent fi rst-level discipline. Currently in China, the teaching and research system of urban-rural planning is facing some problems like the uneven education level among various universities, improper knowledge system that hardly meets the actual social demands, and insufficient theoretical research. This article argues that, in order to train qualif ied planners capable of satisfying socio-economic development and urbanrural construction, the teaching and research system of urban-rural planning should be practice-oriented and meet social needs. The healthy development of urban-rural planning discipline should be based on the mutual promotion of teaching and research system.

关键词： urban-rural planning discipline fi rst-level disci

Assessing the effects of long-term recreational activities on landscape changes in Abant Natural Park,Turkey

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Journal of Forestry Research 2016年第2期27卷 453-461页

作者： Gunay Gakir Haldun Miiderrisoglu Latif Giirkan Kaya department of Forestry and Environmental Sciences Naturaland Applied ScienceGumushane UniversityGumushaneTurkey department of landscape architecture Faculty of ForestryDiizce UniversityDuzceTurkey Faculty of engineering and architecture Mehmet Akif ErsoyUniversityBurdurTurkey

Natural, protected areas offer many possibili- ties for recreation in rural areas such as camping, one of the most popular activities. The system established for pro- tected areas in Turkey aims to provide a foundation for conserving areas for recreation. One such area, Abant Natural Park, is convenient for visits from Turkey＇s two most populated metropolitan areas, Istanbul and Ankara. It also attracts tourists from other regions and countries. The aim of the present study was to evaluate the vegetation loss and land cover changes due to picnic/camping, transhu- mance, and construction over 40 years （1966-2004） in the park using data on visitor numbers, vegetation patches, corridors and connectivity. For evaluating landscape vari- ables, remote sensing data and aerial photos were used. When aerial photos were imported into the ERDAS Imagine program, ground control points identified, and individual images orthorectified, land degradation was not found in the use of camping areas. Moreover, manmade areas （road, car park and hotel） observably increased, thus decreasing the forest lands. The findings show that the land use types that have had the greatest ecological impact are transhumance and construction of hotels, which also require infrastructure development. The intensity of the ecological effects mandates precautions to lessen the impacts and the need for continuing assessment to ensure sustainable use of the area.

关键词： Natural protected areas Remote sensing GIS Forest LULC Abant Natural Park Turkey

Exploration of Practice Teaching Reform Based on Outcome-Based Education Concept:Taking Environmental Design Major as an Example

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Journal of Contemporary Educational Research 2024年第5期8卷 74-79页

作者： Yushan Pang Chongqing Institute of engineering Chongqing 400056China

The concept of OBE(outcome-based education)is more focused on designing and implementing teaching activities around expected learning outcomes than the traditional teaching model and enhancing the quality of education through clear and measurable learning outcomes,which has led to profound changes in the field of ***,environmental design practice teaching faces a series of challenges in the implementation of the OBE concept,including the complexity of the assessment system,personalized learning and creative learning,and over-reliance on quantitative ***,in order to further deepen the professionalization of the OBE concept,we have conducted research on the design education practice models at home and abroad,explored the practice teaching models and their applications such as project system,studio model,practical internships,and technology-driven interdisciplinary integration,and took the practice innovative teaching models of Stanford *** and Rhode Island School of Design(RISD)as examples to explore the characteristics of the curricula,cultivation modes,and the development of the environmental design professional practice teaching *** characteristics of OBE and RISD are discussed to provide a global vision and local contextual reference for the practice teaching reform of environmental design majors.

关键词： Outcome-based education(OBE)concept Practice teaching system Teaching reform Environmental design

In vivo protective effect of late embryogenesis abundant protein(ApSK3 dehydrin)on Agapanthus praecox to promote post-cryopreservation survival

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BIOCELL 2022年第11期46卷 2507-2515页

作者： TINGTING HUANG SHAN DENG JIANGYUAN SHENG DI ZHANG department of landscape Science and engineering School of DesignShanghai Jiao Tong UniversityShanghai200240China Institute for Agri-Food Standards and Testing Technology Shanghai Academy of Agricultural SciencesShanghai201403China

Dehydrins(DHNs),as members of the late embryogenesis abundant protein family,play critical roles in the protection of seeds from dehydration and plant adaptation to multiple abiotic *** is a basic method in plant cryopreservation and is characterized by forming a glassy state to prevent lethal ice crystals produced during cryogenic *** this study,ApSK3 type DHN was genetically transformed into embryogenic calluses(EC)of Agapanthus praecox by overexpression(OE)and RNA interference(RNAi)techniques to evaluate the in vivo protective effect of DHNs during *** cell viability showed a completely opposite trend in OE and RNAi cell lines,the cell relative death ratio was decreased by 20.0%in ApSK3-OE EC and significantly increased by 66.15%in ApSK3-RNAi cells after *** of ApSK3 increased the content of non-enzymatic antioxidants(AsA and GSH)and up-regulated the expression of CAT,SOD,POD,and GPX genes,while ApSK3-RNAi cells decreased antioxidant enzyme activities and FeSOD,POD,and APX genes expression during *** findings suggest that ApSK3 affects ROS metabolism through chelating metal ions(Cu^(2+)and Fe^(3+)),alleviates H_(2)O_(2)and OH·excessive generation,activates the antioxidant system,and improves cellular REDOX balance and membrane lipid peroxidation damage of plant cells during *** can effectively improve cell stress tolerance and have great potential for in vivo or in vitro applications in plant cryopreservation.

关键词： Dehydrin Embryogenic callus Cryopreservation RNAi Gene overexpression