检索结果-南通市图书馆

Effectiveness of out-fracture of the inferior turbinate with reduction nasal bone fracture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第27期11卷 6374-6382页

作者： Se-Young Kim Ha-Jong Nam Je-Yeon Byeon Hwan Jun Choi department of Plastic and reconstructive surgery Soonchunhyang University Gumi HospitalGumi-si 39371South Korea department of Plastic and reconstructive surgery Soonchunhyang University Cheonan HospitalCheonan-si 31151South Korea

BACKGROUND The nasal bone,being the most protruding bone in the center of the facial bones,is particularly susceptible to *** bone fractures can often result in secondary deformation and dysfunction of the nose,including septal *** on functional or intra-nasal complications have been rarely reported after nasal bone fracture *** To evaluate the severity of nasal obstruction and its improvement following nasal bone fracture reduction using inferior *** We conducted a retrospective review of data from 50 patients with symptomatic nasal obstruction between January to December *** patients underwent preoperative Computed tomography evaluation,and symptom changes and nasal cavity volume were analyzed using a visual analog scale and acoustic rhinometry before and after *** reduction and out-fracture of both inferior turbinates performed by the same *** outcomes were assessed by comparing changes in the nasal airway volume measured using acoustic rhinometry before and after *** minimal cross-sectional area(MCA)was also analyzed based on the Stranc *** Before reduction,the mean MCA for all cases was 0.59±0.06 cm^(2),which represented an 11%decrease compared to the average size of a Korean adult(0.65±0.03 cm^(2)).The MCA for frontal impact was 0.60±0.02 cm^(2) and for lateral impact,it was 0.58±0.03 cm^(2).After reduction via inferior turbinoplasty,the MCA improved to 0.64±0.04 cm^(2).CONCLUSION This study suggests that turbinoplasty is helpful in addressing nasal ***-fracture of the inferior turbinate is an effective and durable technique that can be easily performed to enlarge the nasal airway with minimal morbidity.

关键词： Acoustic rhinometry Nasal bone Fracture Turbinate

Strategies for prevention and management of partial flap loss or fat necrosis in microvascular autologous breast reconstruction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plastic and Aesthetic Research 2023年第1期10卷 295-304页

作者： Gabriela D García Nores Angela Cheng department of surgery Division of Plastic and Reconstructive SurgeryEmory UniversityAtlantaGA 30322USA

Partial flap loss(skin involved)or fat necrosis following autologous breast reconstruction remains a dreaded postoperative complication despite significant advances in microsurgical *** strategies have been proposed in the preoperative and intraoperative period to prevent this complication ranging from preoperative imaging,intra-operative tissue perfusion assessment,appropriate perforator selection(location and number),maximizing inflow and outflow with additional anastomoses and/or pedicles,and minimizing ischemia *** management of partial flap loss(when there is skin involvement)and fat necrosis remains a challenge,with very little published data focusing on classification,timing,and *** intervention versus close observation may depend on multiple patient factors and the degree or volume of *** intervention options include hyperbaric oxygen therapy,fat aeration with a needle,liposuction,fat grafting,addition of another flap or implant,depending on the nature of the *** review summarizes the current evidence for each of these strategies to help the current surgeon understand their options in preventing and managing patients suffering from partial flap loss.

关键词： Partial flap loss fat necrosis prevention of fat necrosis

Quinacrine pretreatment reduces microwave-induced neuronal damage by stabilizing the cell membrane

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2018年第3期13卷 449-455页

作者： Xue-feng Ding Yan Wu Wen-rui Qu Ming Fan Yong-qi Zhao department of Cognitive Sciences Beijing Institute of Basic Medical Sciences Hand & Foot surgery and Reparative & reconstructive surgery Center Orthopedic Hospital of the Second Hospital of Jilin University

Quinacrine, widely used to treat parasitic diseases, binds to cell membranes. We previously found that quinacrine pretreatment reduced microwave radiation damage in rat hippocampal neurons, but the molecular mechanism remains poorly understood. Considering the thermal effects of microwave radiation and the protective effects of quinacrine on heat damage in cells, we hypothesized that quinacrine would prevent microwave radiation damage to cells in a mechanism associated with cell membrane stability. To test this, we used retinoic acid to induce PC12 cells to differentiate into neuron-like cells. We then pretreated the neurons with quinacrine （20 and 40 mM） and irradiated them with 50 mW/cm^2 microwaves for 3 or 6 hours. Flow cytometry, atomic force microscopy and western blot assays revealed that irradiated cells pretreated with quinacrine showed markedly less apoptosis, necrosis, and membrane damage, and greater expression of heat shock protein 70, than cells exposed to microwave irradiation alone. These results suggest that quinacrine stabilizes the neuronal membrane structure by upregulating the expression of heat shock protein 70, thus reducing neuronal injury caused by microwave radiation.

关键词： nerve regeneration quinacrine microwave irradiation heat shock cell apoptosis cell necrosis thermal effect cell membrane heat shock protein 70 nerve cells neural regeneration

Expression rates of p16,p53 in head and neck cutaneous squamous cell carcinoma based on human-papillomavirus positivity

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第9期13卷 13-23页

作者： Ha-Jong Nam Heongrae Ryu Da-Woon Lee Je Yeon Byeon Jun Hyuk Kim Ji Hye Lee Soomin Lim Hwan Jun Choi department of Plastic and reconstructive surgery Soonchunhyang University Gumi HospitalGumi-si 39371South Korea department of Plastic and reconstructive surgery College of MedicineSoonchunhyang UniversityCheonan-si 31151South Korea department of Pathology Soonchunhyang University HospitalCheonan-si 31151South Korea Bachelor of Medicine and Bachelor of surgery University College LondonMedical SchoolLondon WC1E 6DEUnited Kingdom

BACKGROUND The high prevalence of human papillomavirus(HPV)infection in oropharyngeal squamous cell carcinoma(SCC)is well established,and p16 expression is a strong ***-related tumors exhibit unique mechanisms that target p16 and p53 ***,research on HPV prevalence and the combined predictive value of p16 and p53 expression in head and neck cutaneous SCC(HNCSCC),particularly in Asian populations,remains *** retrospective study surveyed 62 patients with HNSCC(2011-2020),excluding those with facial warts or other skin *** To explore the prevalence of HPV and the predictive value of p16 and p53 expression in HNCSCC in Asian *** All patients underwent wide excision and *** staining for HPV,p16,and p53 yielded positive and negative *** relevance of each marker was investigated by categorizing the tumor locations into high-risk and middle-risk zones based on recurrence *** Of the 62 patients,20(32.26%)were male,with an average age of 82.27 years(range 26-103 years).High-risk included 19 cases(30.65%),with the eyelid and lip being the most common sites(five cases,8.06%).Middle-risk included 43 cases(69.35%),with the cheek being the most common(29 cases,46.77%).The p16 expression was detected in 24 patients(38.71%),p53 expression in 42 patients(72.58%),and HPV in five patients(8.06%).No significant association was found between p16 expression and the presence of HPV(P>0.99),with a positive predictive value of 8.33%.CONCLUSION This study revealed that p16,a surrogate HPV marker in oropharyngeal SCC,is not reliable in HNCSCC,providing valuable insights for further research in Asian populations.

关键词： Squamous cell carcinoma Oropharyngeal Non-oropharyngeal Human papillomavirus The p16 The p53

The virtual peripheral nerve academy:education for the identification and treatment of peripheral nerve disorders

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plastic and Aesthetic Research 2022年第1期9卷 707-715页

作者： Erica B.Lee Allison Podsednik Kimberly Khoo Amal Cheema Raysa Cabrejo Chen Shen Joseph Rosen A.Lee Dellon department of Plastic and reconstructive surgery Johns Hopkins School of MedicineMD 89011USA department of Plastic and reconstructive surgery The University of Texas Rio Grande ValleyEdinburgTX 78539USA department of Plastic and reconstructive surgery Geisel School of Medicine at DartmouthHanoverNH 03755USA

Millions of people around the globe suffer peripheral nerve injuries caused by trauma and medical ***,medical school curricula are profoundly deficient in peripheral nerve *** lack of knowledge within the healthcare profession may cause inadequate patient *** developed the Virtual Peripheral Nerve Academy(VPNA)as a reusable virtual learning environment to provide medical students with detailed education on the peripheral nervous system(PNS).Students are introduced to the PNS through virtual 3D rendering of the human body,wherein they visualize individual nerves through dissection and observe normal motor and sensory function associated with each *** structures that are absent from traditional texts are included in this visualization,ranging from the innervation of joints to the normal anatomic variation required for differential diagnosis of pain after an *** modules on peripheral nerve disorders allow students to observe pathophysiological mechanisms,associated symptomatology,and appropriate *** are briefed on a patient clinical case,then interact with a patient avatar to learn the appropriate diagnostics,including physical exam maneuvers and electrodiagnostic *** modules on peripheral nerve surgeries detail surgical *** VPNA data and analytics dashboards allow medical students and course instructors to assess skill improvement and identify specific learning *** built-in learner management system and availability on both computer-based and virtual reality platforms facilitate integration into any existing medical school ***,this immersive technology enables every medical student to learn about the peripheral nervous system and gain competency in treating real-life nerve pathologies.

关键词： Virtual reality peripheral nervous system nerve surgical education medical education simulation plastic surgery

Biomechanics of the anterior cruciate ligament:Physiology,rupture and reconstruction techniques

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2016年第2期7卷 82-93页

作者： Christoph Domnick Michael J Raschke Mirco Herbort department of Trauma Hand and Reconstructive SurgeryWestphalian Wilhelms University Muenster

The influences and mechanisms of the physiology,rupture and reconstruction of the anterior cruciate ligament(ACL)on kinematics and clinical outcomes have been investigated in many biomechanical and clinical studies over the last several *** knee is a complex joint with shifting contact points,pressures and axes that are affected when a ligament is *** ACL,as one of the intra-articular ligaments,has a strong influence on the resulting ***,other meniscal or ligamentous injuries accompany ACL ruptures and further deteriorate the resulting kinematics and clinical *** the surgical options,anatomic relations and current evidence to restore ACL function and considering the influence of concomitant injuries on resulting kinematics to restore full function can together help to achieve an optimal outcome.

关键词： Biomechanics anterior cruciate ligament joint pressure anterior cruciate ligament rupture graft fixation anterior cruciate ligament reconstruction

Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第10期17卷 2200-2202页

作者： Pietro G di Summa Srinivas Madduri department of Plastic Reconstructive and Hand SurgeryUniversity Hospital of LausanneUniversity of LausanneLausanneSwitzerland department of surgery Bioengineering and NeuroregenerationUniversity of GenevaUniversity Hospital GenevaGenevaSwitzerland

Despite the spontaneous regenerative capacity of the peripheral nervous system,clinical nerve repair often results in poor functional recovery with the high socio-economic *** presence of peripheral nerve injuries and when distal nerve transfers are not possible,nerve autografts,are the solution of choice to cross a critical nerve ***,these are associated with donor site morbidity and offer only suboptimal functional ***,the need to improve the rate of effective regeneration has directed research attention towards stem cell therapy and nerve tissue engineering.

关键词： injuries donor spite

Post-burn breast reconstruction using an artificial dermis—a long-term follow-up

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Burns & Trauma 2016年第3期4卷 254-257页

作者： Yoav Gronovich Adi Maisel Lotan Meir Retchkiman department of Plastic and reconstructive surgery Shaare-Zedek Medical Center12 Beith StreetJerusalemIsrael

Background:Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive *** is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine *** dermal matrix serves as a scaffold for fibroblasts and endothelial *** of the matrix begins after 2-3 weeks,and eventually,the matrix incorporates with the tissue to create a new *** main advantage of the Integra is that the neodermis is of the same quality as a native *** presentation:In this case report,we present post-burn breast reconstruction of a 12-year-old girl using Integra,with a long follow-up of 7 *** the best of our knowledge,there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has ***:Integra is a reliable reconstructive tool for burned *** done before puberty,it can help in getting normal developing tissue with satisfying esthetic results of size,shape and symmetry.

关键词： Burned breast Integra Artificial skin Burn reconstruction

Diagnostic Power of Diffusion-weighted Magnetic Resonance Imaging for the Presence of Lymph Node Metastasis:A Meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Huazhong University of Science and Technology(Medical Sciences) 2017年第4期37卷 469-474页

作者：孔祥闯熊凌云 Emre Gazyakan Holger Engel Ulrich Kneser Andreas K.Nüssler Christoph Hirche 孔祥泉 department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and Technology department of Plastic and reconstructive surgery Union HospitalTongji Medical CollegeHuazhong University of Science and Technology department of Hand-Plastic and reconstructive surgery Burn CenterBG Trauma Center LudwigshafenUniversity of Heidelberg department of Hand-Plastic and reconstructive surgery Medical Center Kassel Eberhard-Karls-University Tuebingen BG Trauma CenterSiegfried Weller Institut

Present work was designed to quantitatively evaluate the performance of diffusion-weighted magnetic resonance imaging（DWI） in the diagnosis of the presence of metastasis in lymph nodes（LNs）. Eligible studies were identified from systematical Pub Med and EMBASE searches. Data were extracted. Meta-analyses were performed to generate pooled sensitivity and specificity on the basis of per-node, per-lesion and per-patient, respectively. Fourteen publications（2458 LNs, 404 lesions and 334 patients） were eligible. Per-node basis demonstrated the pooled sensitivity and specificity was 0.82（P〈0.0001） and 0.90（P〈0.0001）, respectively. Per-lesion basis illustrated the pooled sensitivity and specificity was 0.73（P=0.0036） and 0.85（P〈0.0001）, respectively. Per-patient basis indicated the pooled sensitivity and specificity was 0.67（P=0.0909） and 0.86（P〈0.0001）, respectively. In conclusion, DWI has rather a negative predictive value for the diagnosis of LN metastasis presence. The difference of the mean apparent diffusion coefficients between benign and malignant LNs is not yet stable. Therefore, the DWI technique has to be further improved.

关键词： Meta-analysis magnetic resonance imaging lymph node metastasis diffusion-weighted