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The Origin of Quarks in Quantum Gravity

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Journal of Modern Physics 2024年第8期15卷 1229-1245页

作者： Edwin Eugene Klingman Cybernetic Micro Systems Inc. San Gregorio USA

A theory of quantum gravity has recently been developed by the author based on the concept that all forces converge to one at the moment of Creation. This primordial field can only interact with itself, as no other field exists, contrasting with the Standard Model of Particle Physics in which each elementary particle is an excitation in its own quantum field. The primordial field theory of quantum gravity has produced a model of a fermion with a mass gap, ½-integral spin, discrete charge, and magnetic moment. The mass gap is based on an existence theorem that is anchored in Yang-Mills, while Calabi-Yau anchors ½-integral spin, with charge and magnetic moment based on duality. Based on N-windings, this work is here extended to encompass fractional charge, with the result applied to quarks, yielding fermion mass and charge in agreement with experiment and novel size correlations and a unique quantum gravity-based ontological understanding of quarks.

关键词： Duality Calabi-Yau Topology Fermion Charge Primordial Field Self-Interaction Equations Yang-Mills Gravity Quantum Gravity Ontology of Quarks

On Perron’s Formula and the Prime Numbers

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Advances in Pure Mathematics 2024年第6期14卷 487-494页

作者： Michael M. Anthony Department of Engineering Enertron Inc. Hohenwald Tennessee USA

The Riemann hypothesis is intimately connected to the counting functions for the primes. In particular, Perron’s explicit formula relates the prime counting function to fixed points of iterations of the explicit formula with particular relations involving the trivial and non-trivial roots of the Riemann Zeta function and the Primes. The aim of the paper is to demonstrate this relation at the fixed points of iterations of explicit formula, defined by functions of the form limT∈Ν→∞fT(zw)=zw,where, zwis a real number.

关键词： Perron Fixed Points Iterations Number Theory Riemann Hypothesis Iterations Invariance Primes

Treatment of SMA type 1 infants using a single-dose AAV9-mediated gene therapy via intrathecal injection of GC101: An open-label, single-arm study

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中华医学杂志(英文版) 2024年第16期137卷 1976-1978页

作者： Ma Xiuwei Zhuang Lu Ma Wenhao Li Jun Wang Xiaodong Li Zhongqiu Jiang Xinyang Wang Yongxia Du Ying Zhang Yingqian He Fang Zhu Zhiming Du Shaopeng Xu Juan Gu Ruijie Zhang Yanping Zhang Shan Li Ting Yang Xiao Zhang Sheng Zhu Lina Li Qiuping Dong Xiaoyan Wu Xiaobing Feng Zhichun Department of Neurodevelopment Faculty of Pediatrics The Seventh Medical Center of Chinese PLA General Hospital Beijing China National Engineering Laboratory for Birth Defects Prevention and Control of Key Technology Beijing China Research and Development Division Genecradle Therapeutics Inc. Beijing China Medical Division Genecradle Therapeutics Inc. Beijing China Department of Pharmacy Medical Supplies Center of Chinese PLA General Hospital Beijing China Beijing Key Laboratory of Pediatric Organ Failure Beijing China

A Review on the Security of the Ethereum-Based DeFi Ecosystem

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 69-101页

作者： Yue Xue Dunqiu Fan Shen Su Jialu Fu Ning Hu Wenmao Liu Zhihong Tian Cyberspace Institute of Advanced Technology Guangzhou UniversityGuanzhou510000China Innovation Center NSFOCUS Inc.Beijing100089China Engineering Research Center of Integration and Application of Digital Learning Technology Ministry of EducationBeijing100816China

Decentralized finance(DeFi)is a general term for a series of financial products and *** is based on blockchain technology and has attracted people’s attention because of its open,transparent,and intermediary *** them,the DeFi ecosystem based on Ethereum-based blockchains attracts the most ***,the current decentralized financial system built on the Ethereum architecture has been exposed to many smart contract vulnerabilities during the last few ***,we believe it is time to improve the understanding of the prevailing Ethereum-based DeFi ecosystem security *** that end,we investigate the Ethereum-based DeFi security issues:1)inherited from the real-world financial system,which can be solved by macro-control;2)induced by the problems of blockchain architecture,which require a better blockchain platform;3)caused by DeFi invented applications,which should be focused on during the project *** on that,we further discuss the current solutions and potential directions ofDeFi *** to our research,we could provide a comprehensive vision to the research community for the improvement of Ethereum-basedDeFi ecosystem security.

关键词： Blockchain smart contract decentralized finance DeFi security

Numerical Simulation of Radial Ultrasonic Assisted MIG Welding Arc

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Journal of Shanghai Jiaotong university(Science) 2024年第2期29卷 330-338页

作者：洪蕾肖皓叶佳马国红 Key Laboratory of Lightweight and High Strength Structural Materials of Jiangxi Provinc. School of Mechanical EngineeringNanchang UniversityNanchang 330031China Applied Materials Inc.Santa ClaraCA 95054-3299USA

The numerical simulation of arc was carried out for both conventional melt inert gas(MIG)welding and ultrasonic assisted melt inert gas(U-MIG)*** on the model established by Fluent,the arc shape,temperature field,and potential distribution were *** study found that the shape of the arc changed when ultrasonic was added radially;the high-temperature area of the arc stretched,and the temperature peak *** as the current inc.eased,the inc.ease in temperature *** addition,under the same conditions,the potential of U-MIG decreased and the pressure on the workpiece *** verify the accuracy of the simulation results,welding experiments under identical conditions were carried out,and a high-speed camera was used to collect dynamic pictures of the *** simulation results were in a favorable agreement with the experimental results,which provided a certain reference value for ultrasonic assisted arc welding.

关键词： numerical simulation welding arc ultrasonic arc welding arc temperature

The Origin of Electric Charge in Quantum Gravity

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Journal of Modern Physics 2024年第4期15卷 511-535页

作者： Edwin Eugene Klingman Cybernetic Micro Systems Inc. San Gregorio CA USA

A model fermion has been produced in a theory of quantum gravity that establishes the existence of a mass gap and half-integral spin. The third requirement for the fermion is electric charge. We herein develop a dualism-based analysis that explains the origin of charge at the fermion scale in a primordial field theory of quantum gravity.

关键词： Duality Topology Parallel Transport Particle Genesis Primordial Field Self-Interaction Equations Yang-Mills Gravity

Calabi-Yau Topology of Primordial Fermions

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Journal of Modern Physics 2024年第1期15卷 132-158页

作者： Edwin Eugene Klingman Cybernetic Micro Systems Inc. San Gregorio CA USA

Quantum field theory creates fermions via abstract operators exciting abstract fields, with a specific field for each type of specific particle. This operator algebra lends itself well to quantum statistics, nevertheless, our physical understanding of this process is nonintuitive at best. In this paper we analyze the creation of fermions from primordial gauge field quantum gravity loops in the context of Calabi-Yau manifold theory. I extend a prior mass-gap treatment based on Yang-Mills gauge theory of higher order self-interaction to inc.ude the half-integral spin of fermions.

关键词： Calabi-Yau Topology Fermion Spin Particle Genesis Primordial Field Self-Interaction Equations Yang-Mills Gravity

Development of novel 5-FU modified siRNA against BCL-2 with enhanced efficacy and vehicle-free cellular uptake

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Genes & Diseases 2024年第1期11卷 23-25页

作者： Andrew Fesler Ga-Ram Hwang Jingfang Ju Department of Pathology Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA The Northport Veteran's Administration Medical Center NorthportNY 11768USA Curamir Therapeutics inc. WoburnMA 01801USA

One of the major obstacles for nucleic acid-based medicine is cellular uptake due to the concern of efficiencyand potential toxicity of the *** this work,we developed a novel approach to eliminate the need for a vehicle to allow for the cellular uptake of siRNA-based therapy with a unique modification strategy that also further enhances therapeutic *** discovery may be of great importance for the development of siRNA-based therapeutics as cellular uptake remains a critical *** this study,we have tested the potential of this modification strategy for siRNA using a siRNA that targets B-cell lymphoma-2(BCL-2).

关键词： eliminate uptake modified

Drought-Tolerant Rice at Molecular Breeding Eras:An Emerging Reality

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Rice science 2024年第2期31卷 179-189页

作者： ZHU Chengqi YE Yuxuan QIU Tian HUANG Yafan YING Jifeng SHEN Zhicheng Institute of Insect Sciences Zhejiang UniversityHangzhou 310058China Performance Plants inc. 1287 Gardiners RoadKingstonOntario K7P 3J6Canada China National Rice Research Institute Hangzhou 310006China

Rice(Oryza sativa L.)stands as the most significantly influential food crop in the developing world,with its total production and yield stability affected by environmental *** stress impacts about 45%of the world’s rice area,affecting plants at molecular,biochemical,physiological,and phenotypic *** conventional breeding method,predominantly employing single pedigree selection,has been widely utilized in breeding numerous drought-tolerant rice varieties sinc. the Green *** rapid progress in plant molecular biology,hundreds of drought-tolerant QTLs/genes have been identified and tested in rice crops under both indoor and field *** genes have been introgressed into elite germplasm to develop commercially accepted drought-tolerant varieties,resulting in the development of several drought-tolerant rice varieties through marker-assisted selection and genetically engineered *** review provides up-to-date information on proof-of-concept genes and breeding methods in the molecular breeding era,offering guidance for rice breeders to develop drought-tolerant rice varieties.

关键词： conventional breeding drought stress drought tolerant rice genetic engineering marker-assisted selection breeding