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High frame rate multi-resonance imaging refractometry with distributed feedback dye laser sensor

Light(Science & Applications) 2015年第1期4卷 410-414页

作者： Christoph Vannahme Martin Dufva Anders Kristensen Technical University of Denmark Department of Micro-and NanotechnologyDTU NanotechDK-2800 Kgs.LyngbyDenmark

High frame rate and highly sensitive imaging of refractive index changes on a surface is very promising for studying the dynamics of dissolution,mixing and biological processes without the need for ***,a highly sensitive distributed feedback(DFB)dye laser sensor for high frame rate imaging refractometry without moving parts is *** dye lasers are low-cost and highly sensitive refractive index *** unique multi-wavelength DFB laser structure presented here comprises several areas with different grating *** two dimensions of space is enabled by analyzinglaser light from all areasin parallelwith an imaging *** this multi-resonance imaging refractometry method,the spatial position in one direction is identified from the horizontal,i.e.,spectral position of the multiple laser lines which is obtained from the spectrometer charged coupled device(CCD)*** orthogonal spatial position is obtained from the vertical spatial position on the spectrometer CCD array as in established spatially resolved ***,the imaging technique is demonstrated by monitoring the motion of small sucrose molecules upon dissolution of solid sucrose in *** omission of moving parts improves the robustness of the imaging system and allows a very high frame rate of up to 12 Hz.

关键词： distributed feedback laser label-free imaging laser sensor refractive index sensor

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Large-area nanopatterned graphene for ultrasensitive gas sensing

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Nano Research 2014年第5期7卷 743-754页

作者： Alberto Cagliani David Micheal Angus Mackenzie Lisa Katharina Tschammer Filippo Pizzocchero Kristoffer Almdal Peter Boggild dtu nanotech-Center for Nanostructured Graphene (CNG) and Department of Micro- and nanotechnology Technical University ofDenmark Building 345 ~rsteds Plads 2800 Kgs. Lyngby Denmark

Chemical vapor deposited (CVD) graphene is nanopatterned using a spherical block copolymer etch mask. The use of spherical rather than cylindrical block copolymers allows homogeneous patterning of cm-scale areas without any substrate surface treatment. Raman spectroscopy was used to study the controlled generation of point defects in the graphene lattice with increasing etching time, confirming that alongside the nanomesh patterning, the nanopatterned CVD graphene presents a high defect density between the mesh holes. The nanopatterned samples showed sensitivities for NO2 of more than one order of magnitude higher than for non-patterned graphene. NO2 concentrations as low as 300 ppt were detected with an ultimate detection limit of tens of ppt. This is the smallest value reported so far for non-UV illuminated graphene chemiresistive NO2 gas sensors. The dramatic improvement in the gas sensitivity is believed to be due to the high adsorption site density, thanks to the combination of edge sites and point defect sites. This work opens the possibility of large area fabrication of nanopatterned graphene with extremely high densities of adsorption sites for sensing applications.

关键词：气体传感器石墨面积化学气相沉积法超灵敏嵌段共聚物缺陷密度 NO2

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3D-printed bioactive scaffolds from nanosilicates and PEOT/PBT for bone tissue engineering

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Regenerative Biomaterials 2019年第1期6卷 29-37页

作者： James K.Carrow Andrea Di Luca Alireza Dolatshahi-Pirouz Lorenzo Moroni Akhilesh K.Gaharwar Department of Biomedical Engineering Texas A&M UniversityCollege StationTX 77843USA Tissue Regeneration Department MIRA Institute for Biomedical Technology and Technical MedicineUniversity of TwenteEnschedeThe Netherlands dtu nanotech Center for Intestinal Absorption and Transport of BiopharmaceuticalsTechnical University of Denmark2800 KgsLyngbyDenmark Department of Complex Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht UniversityUniversiteitsingel 406229ER MaastrichtThe Netherlands Department of Materials Science Texas A&M UniversityCollege StationTX 77843USA Center for Remote Health Technologies and Systems Texas A&M UniversityCollege StationTX 77843USA

Additive manufacturing(AM)has shown promise in designing 3D scaffold for regenerative ***,many synthetic biomaterials used for AM are ***,we report synthesis of bioactive nanocomposites from a poly(ethylene oxide terephthalate)(PEOT)/poly(butylene terephthalate)(PBT)(PEOT/PBT)copolymer and 2D nanosilicates for fabricating 3D scaffolds for bone tissue ***/PBT have been shown to support calcification and bone bonding ability in vivo,while 2D nanosilicates induce osteogenic differentiation of human mesenchymal stem cells(hMSCs)in absence of osteoinductive *** effect of nanosilicates addition to PEOT/PBT on structural,mechanical and biological properties is ***,the addition of nanosilicate to PEOT/PBT improves the stability of nanocomposites in physiological conditions,as nanosilicate suppressed the degradation rate of ***,no significant increase in the mechanical stiffness of scaffold due to the addition of nanosilicates is *** addition of nanosilicates to PEOT/PBT improves the bioactive properties of AM nanocomposites as demonstrated in *** readily proliferated on the scaffolds containing nanosilicates and resulted in significant upregulation of osteo-related proteins and production of mineralized *** synergistic ability of nanosilicates and PEOT/PBT can be utilized for designing bioactive scaffolds for bone tissue engineering.

关键词： 3D printing nanocomposites two dimensional(2D)nanoparticles copolymer tissue engineering

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