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Injection medialization laryngoplasty improves dysphagia in patients with unilateral vocal fold immobility

World Journal of Otorhinolaryngology-Head and Neck Surgery 2018年第2期4卷 126-129页

作者： Mursalin M. Anis Zainulabideen Memon coastal ear Nose and Throat Neptune NJ USA Department of Otolaryngology University of Miami Miami FL USA Jersey Shore University Medical Center Neptune NJ USA

Objective: To assess patient reported swallowing outcomes before and after injec-tion medialization laryngoplasty in patients with unilateral vocal fold immobility (UVFI). Methods: Case series with chart review of patients with UVFI who underwent injection media-lization laryngoplasty at a community laryngology practice by a single clinician between October 2015 and December 2017. Patient-reported validated surveys of swallowing impair-ment, Eating Assessment Tool (EAT-10), demographics, etiology and duration of symptoms were recorded before and after injection. A paired t test was done on EAT-10 surveys before and after IML to assess for statistical significance. Results: Twenty-one patients with UVFI and glottic insufficiency underwent IML between October 2015 and December 2017. Nineteen of 21 patients (90％) presented with dysphagia (EAT-10 ≥ 3). 76％ of patients with dysphagia reported improvement in swallowing function af-ter IML. The EAT-10 scores of UVFI patients with dysphagia before and after IML were 17.0 ± 14.0 and 4.2 ± 9.6, respectively (p = 0.004). Conclusions: Nearly all patients with UVFI and glottic insufficiency report associated dysphagia. Three fourths of these patients perceive improvement in their swallowing function after injection medialization laryngoplasty. Patients with idiopathic UVFI may have a more sus-tained improvement and those with severe preop dysphagia may not benefit. Further research is necessary to refine patient selection and to assess duration of improved swallowing function.

关键词： Unilateral vocal fold immobility Glottic insufficiency Dysphagia Eating assessment tool Injection medialization laryngoplasty

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Protoraphis Simonsen, a newly recorded marine epizoic diatom genus for China

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Acta Oceanologica Sinica 2020年第4期39卷 120-126页

作者： Lang Li Changping Chen Lin Sun Jiawei Zhang Junrong Liang Yahui Gao School of Life Sciences Xiamen UniversityXiamen 361102China Key Laboratory of Ministry of Education for coastal and Wetland Ecosystems Xiamen UniversityXiamen 361102China State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361102China

Epizoic diatoms on marine copepods are common in nature and may have a special ecological relationship with their ***,this special ecological group is not well known,and it has only rarely been studied in the China *** address this knowledge gap,the species diversity and classification of epizoic diatoms on planktonic copepods were studied with samples collected from the East China *** the present study,a marine araphid diatom genus Protoraphis and its type species,***,were observed and identified by light and electron microscopy,thus representing the first record of this genus and its type species in *** genus is characterized by a median sternum strongly bent to opposite sides and terminate in two transapical grooves at the valve *** hustedtiana was found to be epizoic on the posterior body appendages and segments of the marine calanoid copepod Candacia *** internal view shows a complex,ear-shaped process that is close to the apical slit *** ecological habitats and geographical distributions of Protoraphis were also discussed,and,together with complementary morphological studies,our results have increased the number of records for marine epizoic diatoms to three genera with three species in China,including Pseudohimantidium and Pseudofalcula.

关键词： marine epizoic diatom copepod Protoraphis newly recorded genus ear-shaped process

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Association of gastroesophageal reflux disease and laryngeal cancer

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2018年第4期4卷 278-281页

作者： Mursalin M.Anis Mir-Muhammad Razavi Xiao Xiao Ahmed M.S.Soliman coastal ear Nose and ThroatJersey Shore University Medical CenterNeptuneNJUSA Lewis Katz School of Medicine at Temple University PhiladelphiaPAUSA Department of Statistics Fox School of BusinessTemple UniversityPhiladelphiaPAUSA Department of Otolaryngology e Head and Neck Surgery Lewis Katz School of Medicine at Temple UniversityPhiladelphiaPAUSA

Objective:Studies examining the association of reflux disease with the risk of developing laryngeal cancer have both proven and disproven the null ***:This retrospective caseecontrol study examines the association of reflux in two populations exposed to similar risk factors,including tobacco,to the extent that end-organ malignant transformation has *** IRB approval was obtained,a search of our hospital’s cancer center’s database was performed from 2000 to 2013.A retrospective chart review was then performed and the prevalence of gastroesophageal reflux disease among patients with laryngeal cancer(n Z 290)was *** was then compared to the prevalence of gastroesophageal reflux disease among patients presenting with lung cancer(n Z 2440)during the same time period.A multivariate logistic regression was performed to determine the association of reflux with laryngeal ***:Taking into consideration tobacco use,there was a strong association between male gender and occurrence of laryngeal cancer as opposed to lung cancer(OR Z 3.30;95%CI 2.53e4.36,Pearch is necessary to determine the biologic relevance of this finding.

关键词： Laryngopharyngeal reflux GERD Extraesophageal reflux Laryngeal cancer Lung cancer

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