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Effect of integrated traditional Chinese and Western medicine on SARS:A review of clinical evidence

World Journal of Gastroenterology 2004年第23期10卷 3500-3505页

作者： Ming-MingZhang Xue-MeiLiu LinHe chineseevidence-basedmedicinecenter WestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina EditorialDepartment ChineseJournalofEvidenceBasedMedicineChineseEvidence-BasedMedicineCenterWestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina LibraryofWestChinaHospital SichuanUniversityChengdu610041SichuanProvinceChina

AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory ***: The current available randomized controlled trials of integrated tradilJonal Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of *** studies of gray literature were also *** quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane ***: Six studies (n = 366) fulfilling the inclusion criteria were found, of which the quality of one study was graded as B, the remaining five were graded as C. Two studies were performed with meta-analysis, the other four studies existed some heterogeneity for which meta-analysis could not be performed, a significant effect on lung infiltrate absorption was found in the treatment groups of these two studies [RR 6.68, 95% CI (2.93, 15.24), P<0.01], there was no significant differences between the mortality [RR 0.86, 95% CI (0.22, 3.29), P = 0.82] and the average dosage of corticosteroid [WMD -39.65, 95% CI (-116.84, 37.54),P = 0.31]. The other three studies also showed significant differences in infiltrate absorption, including national drug No. 2. 3.4 in combination with Western medicine [RR 5.45,95% CI (1.54, 19.26)], compound formulas NO. 1 combined with Western medicine [WMD 0.24, 95% CI (0.02, 0.46)],compound formulas combined with Western medicine [RR 8.06, 95% CI (0.40, 163.21)]. Kangfeidian No.4 in combination with Western medicine had no significant effect on symptomim provement such as loss of dyspnea and cough [RR 1.50,95%CI (0.41, 5.43)] and [RR 1.29, 95%C1 (0.30, 5.43)].CONCLUSION: Integrated traditional Chinese and Westernm edicines has some positive effects on lung infiltrate absorption in SARS pat

关键词：中医西医 SARS 临床作用呼吸系统

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Intravenous chemotherapy for resected gastric cancer:meta-analysis of randomized controlled trials

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World Journal of Gastroenterology 2002年第6期8卷 1023-1028页

作者： Jian-KunHu Zhi-xinChen Zong-GuangZhou BoZhang JingTian Jia-Pin chineseevidence-BasedMedicine/CochraneCenter Chengdu610041SichuanProvinceChina GeneralSurgeryDepartment WestChinaHospitalofSichuanUniversityChengdu610041SichuanProvinceChina

AIM: To assess the safety and efficacy of different intravenous chemotherapeutic regimens in patiedts with gastric acrcinomas who had undergone gastrectomy.

关键词：胃肠癌切除手术后静脉内化疗随机控制试验主成分分析

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Clinical evidence of growth hormone for patients undergoing abdominal surgery: Meta-analysis of randomized controlled trials

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World Journal of Gastroenterology 2005年第25期11卷 3925-3930页

作者： YongZhou Xiao-TingWu GangYang WenZhuang Mao-LingWei DepartmentofGeneralSurgery WestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina chineseevidence-BasedMedicine/CochraneCenter Chengdu610041SichuanProvinceChina

AIM: To assess the effectiveness and safety of perioperative growth hormone (GH) in patients undergoing abdominal ***: We searched the following electronic databases: MEDLINE, EMBASE, the Cochrane Controlled Trials Register, Chinese Bio-medicine Database. The search was undertaken in February 2003. No language restrictions were applied. Randomized controlled trials (RCT) comparing GH with placebo in patients undergoing abdominal surgery were extracted and *** quality was evaluated using the Jadad ***: Eighteen trials involving 646 patients were included. The combined results showed that GH had a positive effect on improving postoperative nitrogen balance (standardized mean difference [SMD] = 3.37, 95%CI [2.46, 4.27], P＜0.00001), and decreasing the length of hospital stay (weighted mean difference [WMD] = -2.07,95%CI [-3.03, -1.11], P = 0.00002), and reducing the duration of postoperative fatigue syndrome (SMD = -1.83,95%CI [-2.37, -1.30], P＜0.00001), but it could increase blood glucose levels (WMD = 0.91, 95%CI [0.56, 1.25],P＜0.00001).CONCLUSION: GH for patients undergoing abdominal surgery is effective and safe, if blood glucose can be controlled well. Further trials are required with a sufficient size to account for clinical heterogeneity and to measure other important outcomes such as infection, morbidity,mortality, fluid retention, immunomodulatory effects, and tumor recurrence.

关键词： Perioperative growth hormone Abdominal surgery

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