Effect of integrated traditional Chinese and Western medicine on SARS:A review of clinical evidence

作     者：Ming-MingZhang Xue-MeiLiu LinHe 

作者机构：ChineseEvidence-BasedMedicineCenterWestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina EditorialDepartmentChineseJournalofEvidenceBasedMedicineChineseEvidence-BasedMedicineCenterWestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina LibraryofWestChinaHospitalSichuanUniversityChengdu610041SichuanProvinceChina 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2004年第10卷第23期

页      面：3500-3505页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：中医 西医 SARS 临床作用 呼吸系统 

摘      要：AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory ***: The current available randomized controlled trials of integrated tradilJonal Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of *** studies of gray literature were also *** quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane ***: Six studies (n = 366) fulfilling the inclusion criteria were found, of which the quality of one study was graded as B, the remaining five were graded as C. Two studies were performed with meta-analysis, the other four studies existed some heterogeneity for which meta-analysis could not be performed, a significant effect on lung infiltrate absorption was found in the treatment groups of these two studies [RR 6.68, 95% CI (2.93, 15.24), P0.01], there was no significant differences between the mortality [RR 0.86, 95% CI (0.22, 3.29), P = 0.82] and the average dosage of corticosteroid [WMD -39.65, 95% CI (-116.84, 37.54),P = 0.31]. The other three studies also showed significant differences in infiltrate absorption, including national drug No. 2. 3.4 in combination with Western medicine [RR 5.45,95% CI (1.54, 19.26)], compound formulas NO. 1 combined with Western medicine [WMD 0.24, 95% CI (0.02, 0.46)],compound formulas combined with Western medicine [RR 8.06, 95% CI (0.40, 163.21)]. Kangfeidian No.4 in combination with Western medicine had no significant effect on symptomim provement such as loss of dyspnea and cough [RR 1.50,95%CI (0.41, 5.43)] and [RR 1.29, 95%C1 (0.30, 5.43)].CONCLUSION: Integrated traditional Chinese and Westernm edicines has some positive effects on lung infiltrate absorption in SARS pat