检索结果-南通市图书馆

Enhancing IoT anomaly detection performance for federated learning

Digital Communications and Networks 2022年第3期8卷 314-323页

作者： Brett Weinger Jinoh Kim Alex Sim Makiya Nakashima Nour Moustafa K.John Wu stony brook university Stony BrookNYUSA Lawrence Berkeley National Laboratory BerkeleyCAUSA Texas A&M university CommerceTXUSA university of New South Wales CanberraAustralia

Federated Learning (FL) with mobile computing and the Internet of Things (IoT) is an effective cooperative learning approach. However, several technical challenges still need to be addressed. For instance, dividing the training process among several devices may impact the performance of Machine Learning (ML) algorithms, often significantly degrading prediction accuracy compared to centralized learning. One of the primary reasons for such performance degradation is that each device can access only a small fraction of data (that it generates), which limits the efficacy of the local ML model constructed on that device. The performance degradation could be exacerbated when the participating devices produce different classes of events, which is known as the class balance problem. Moreover, if the participating devices are of different types, each device may never observe the same types of events, which leads to the device heterogeneity problem. In this study, we investigate how data augmentation can be applied to address these challenges and improving detection performance in an anomaly detection task using IoT datasets. Our extensive experimental results with three publicly accessible IoT datasets show the performance improvement of up to 22.9% with the approach of data augmentation, compared to the baseline (without relying on data augmentation). In particular, stratified random sampling and uniform random sampling show the best improvement in detection performance with only a modest increase in computation time, whereas the data augmentation scheme using Generative Adversarial Networks is the most time-consuming with limited performance benefits.

关键词： Data augmentation Federated learning Internet of things Anomaly detection Machine learning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nanocrystal technology for drug formulation and delivery

引用

Frontiers of Chemical Science and Engineering 2015年第1期9卷 1-14页

作者： Tzu-Lan CHANG Honglei ZHAN Danni LIANG Jun F. LIANG department of chemistry Chemical Biology and Biomedical Engineering Charles V. Schaefer School of Engineering and Sciences Stevens Institute of Technology Hoboken NJ 07030 USA stony brook university School of Medicine Stony Brook NY 11794 USA

With the development of modem technology like high throughput screening, combinatorial chemistry and computer aid drug design, the drug discovery process has been dramatically accelerated. However, new drug candidates often exhibit poor aqueous or even organic medium solubility. Additionally, many of them may have low dissolution velocity and low oral bioavailability. Nanocrystal formulation sheds new light on advanced drug development. Due to small （nano- or micro- meters） sizes, the increased surface-volume ratio leads to drama- tically enhanced drug dissolution velocity and saturation solubility. The simplicity in preparation and the potential for various administration routes allow drug nanocrystals to be a novel drug delivery system for specific diseases （i.e. cancer）. In addition to the comprehensive review of different technologies and methods in drug nanocrystal preparation, suspension, and stabilization, we will also compare nano- and micro-sized drug crystals in pharma- ceutical applications and discuss current nanocrystal drugs on the market and their limitations.

关键词： drug nanocrystal nanotechnology formula-tion bioavailability stabilizers drug delivery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Repeated hydrogen peroxide dosing briefly reduces cyanobacterial blooms and microcystin while increasing fecal bacteria indicators in a eutrophic pond

引用

Journal of Environmental Sciences 2023年第2期124卷 522-543页

作者： Mark W.Lusty Christopher J.Gobler School of Marine and Atmospheric Sciences Stony Brook UniversitySouthamptonNY 11968USA

This study explored the effects of H_(2)O_(2)on Cyanobacteria and non-target microbes using fluorometry,microscopy,flow cytometry,and high throughput DNA sequencing of the 16S rRNA gene during a series of mesocosm and whole-ecosystem experiments in a eutrophic pond in NY,*** addition of H_(2)O_(2)(8 mg/L)significantly reduced Cyanobacteria concentrations during a majority of experiments(66%;6 of 9)and significantly increased eukaryotic green and unicellular brown algae in 78%and 45%of experiments,*** heterotrophic bacteria declined significantly following H_(2)O_(2)addition in all experiments,bacteria indicative of potential fecal contamination(Escherichia coli,Enterococcus,fecal coliform bacteria)consistently and significantly increased in response to H_(2)O_(2),evidencing a form of‘pollution swapping’.H_(2)O_(2)more effectively reduced Cyanobacteria in enclosed mesocosms compared to whole-ecosystem *** whole-pond H_(2)O_(2)applications over a twoyear period temporarily reduced cyanobacterial levels but never reduced concentrations below bloom thresholds and populations always rebounded in two weeks or *** bacterial phyla of Cyanobacteria,Actinobacteria,and Planctomycetes were the most negatively impacted by H_(2)O_(2).Microcystis was always reduced by H_(2)O_(2),as was the toxin microcystin,but Microcystis remained dominant even after repeated H_(2)O_(2)*** H_(2)O_(2)favored the growth of eukaryotic algae over potentially harmful Cyanobacteria,the inability of H_(2)O_(2)to end cyanobacterial blooms in this eutrophic waterbody suggests it is a non-ideal mitigation approach in high biomass ecosystems and should be used judiciously due to potential negative impacts on non-target organisms and promotion of bacteria indicative of fecal contamination.

关键词： Indicator bacteria Toxic cyanobacteria Microcystin Microcystis Hydrogen peroxide Bacteria Enterococcus E.coli Pollution swapping

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Noisy-intermediate-scale quantum power system state estimation

引用

iEnergy 2024年第3期3卷 135-141页

作者： Fei Feng Peng Zhang Yifan Zhou Yacov A.Shamash department of Engineering SUNY Maritime CollegeBronxNY 10465USA department of Electrical and Computer Engineering Stony Brook UniversityStony BrookNY 11794-2350USA

Quantum power system state estimation(QPSSE)offers an inspiring direction for tackling the challenge of state estimation through quantum ***,the current bottlenecks originate from the scarcity of practical and scalable QPSSE methodologies in the noisy intermediate-scale quantum(NISQ)*** paper devises a NISQ−QPSSE algorithm that facilitates state estimation on real NISQ *** new contributions include:(1)A variational quantum circuit(VQC)-based QPSSE formulation that empowers QPSSE analysis utilizing shallow-depth quantum circuits;(2)A variational quantum linear solver(VQLS)-based QPSSE solver integrating QPSSE iterations with VQC optimization;(3)An advanced NISQ-compatible QPSSE methodology for tackling the measurement and coefficient matrix issues on real quantum computers;(4)A noise-resilient method to alleviate the detrimental effects of noise *** encouraging test results on the simulator and real-scale systems affirm the precision,universal-ity,and scalability of our QPSSE algorithm and demonstrate the vast potential of QPSSE in the thriving NISQ era.

关键词： Quantum computing state estimation variational quantum linear solver noisy-intermediate-scale quantum(NISQ)era

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interactions Between Extracellular Vesicles and Autophagy in Neuroimmune Disorders

引用

Neuroscience Bulletin 2024年第7期40卷 992-1006页

作者： Xiwen Ai Haojun Yu Yu Cai Yangtai Guan department of Neurology Shanghai Jiao Tong University School of Medicine Affiliated Renji HospitalShanghai 200127China department of Neurology Renaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA

Neuroimmune disorders,such as multiple sclerosis,neuromyelitis optica spectrum disorder,myasthenia gravis,and Guillain–Barrésyndrome,are characterized by the dysfunction of both the immune system and the nervous *** evidence suggests that extracellular vesicles and autophagy are closely associated with the pathogenesis of these *** this review,we summarize the current understanding of the interactions between extracellular vesicles and autophagy in neuroimmune disorders and discuss their potential diagnostic and therapeutic *** we highlight the need for further research to fully understand the mechanisms underlying these disorders,and to develop new diagnostic and therapeutic strategies.

关键词： Autophagy Extracellular vesicles Neuroimmune disorders Multiple sclerosis Neuromyelitis optica spectrum disorder Myasthenia gravis Guillain-Barrésyndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Concurrent optimization of structural topology and infill properties with a CBF-based level set method

引用

Frontiers of Mechanical Engineering 2019年第2期14卷 171-189页

作者： Long JIANG Yang GUO Shikui CHEN Peng WEI Na LEI Xianfeng David GU department of Mechanical Engineering State University of New York at Stony BrookStony BrookNY 11794USA department of Computer Science State University of New York at Stony BrookStony BrookNY 11794USA State Key Laboratory of Subtropical Building Science School of Civil Engineering and TransportationSouth China University of TechnologyGuangzhou 510641China DUT-RU International School of Information Science&Engineering Dalian University of TechnologyDalian 116620China

In this paper,a parametric level-set-based topology optimization framework is proposed to concurrently optimize the structural topology at the macroscale and the effective infill properties at the micro/meso *** concurrent optimization is achieved by a computational framework combining a new parametric level set approach with mathematical *** the proposed framework,both the structural boundary evolution and the effective infill property optimization can be driven by mathematical programming,which is more advantageous compared with the conventional partial differential equatiodriven level set ***,the proposed approach will be more efficient in handling nonlinear problems with multiple *** of using radial basis functions(RBF),in this paper,we propose to construct a new type of cardinal basis functions(CBF)for the level set function *** proposed CBF parameterization ensures an explicit impose of the lower and upper bounds of the design *** overcomes the intrinsic disadvantage of the conventional RBF-based parametric level set method,where the lower and upper bounds of the design variables oftentimes have to be set by trial and error;A variational distance regularization method is utilized in this research to regularize the level set function to be a desired distanceregularized *** the distance information embedded in the level set model,the wrapping boundary layer and the interior infill region can be naturally *** isotropic infill achieved via the mesoscale topology optimization is conformally fit into the wrapping boundary layer using the shape-preserving conformal mapping method,which leads to a hierarchical physical structure with optimized overall topology and effective infill *** proposed method is expected to provide a timely solution to the increasing demand for multiscale and multifunctional structure design.

关键词： concurrent topology optimization parametric level set method cardinal basis function shell-infill structure design confonnal mapping

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Haptics-equiped interactive PCI simulation for patient-specific surgery training and rehearsing

引用

Science China(Information Sciences) 2016年第10期59卷 233-238页

作者： Shuai LI Qing XIA Aimin HAO Hong QIN Qinping ZHAO State Key Laboratory of Virtual Reality Technology and Systems Beihang University department of Computer Science Stony Brook University

Despite the long history of medical simulations, suffering from the patient-specific heterogeneous heart physiological structure and complex intravascular procedures, it is still challenging for patient-specific percutaneous coronary intervention(PCI) surgery simulation. In this paper, we advocate a haptics-equiped interactive prototype system towards PCI surgeons training and patient-specific surgery rehearsing, which can afford trainees the opportunity to approximately experience the entire PCI procedures and customized emergency cases that might occur in common clinical settings. The full simulation covers tissue deformation, catheter and wire simulation, X-ray simulation, haptic feedback, and 3D realistic rendering, which in all give rise to the integrated physical, visual, haptic, and procedural realism. Our system can accommodate various comprehensive operations involved in PCI-related procedures, including feeding wires, releasing stents, injecting contrast medium, simulating X-ray, bleeding, etc. Moreover, our system framework is fully built upon CUDA, and thus can achieve real-time performance even on a common desktop. The high-fidelity, real-time efficiency and stableness of our system show great potentials for its practical applications in clinical training fields.

关键词： percutaneous coronary intervention(PCI) PCI surgery simulation patient-specific surgery rehearsing physically-based modeling haptics

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Deciphering the dual role and prognostic potential of PINK1 across cancer types

引用

Neural Regeneration Research 2021年第4期16卷 659-665页

作者： Katherine Dai Daniel P.Radin Donna Leonardi department of Molecular Cellularand Developmental BiologyYale UniversityNew HavenCTUSA department of Pharmacology Stony Brook University School of MedicineStony BrookNYUSA Bergen County Academies HackensackNJUSA

Metabolic rewiring and deregulation of the cell cycle are hallmarks shared by many *** mutations in key tumor suppressor genes,such as PTEN,and oncogenes predispose cancer cells for marked utilization of resources to fuel accelerated cell proliferation and chemotherapeutic *** research has demonstrated that PTEN-induced putative kinase 1(PINK1)acts as a pivotal regulator of mitochondrial homeostasis in several cancer types,a function that also extends to the regulation of tumor cell proliferative *** addition,involvement of PINK1 in modulating inflammatory responses has been highlighted by recent studies,further expounding PINK1’s multifunctional *** review discusses the oncogenic roles of PINK1 in multiple tumor cell types,with an emphasis on maintenance of mitochondrial homeostasis,while also evaluating literature suggesting a dual oncolytic mechanism based on PINK1’s modulation of the Warburg *** a clinical standpoint,its expression may also dictate the response to genotoxic stressors commonly used to treat multiple *** detailing the evidence suggesting that PINK1 possesses distinct prognostic value in the clinical setting and reviewing the duality of PINK1 function in a context-dependent manner,we present avenues for future studies of this dynamic protein.

关键词： apoptosis cancer cell cycle inflammation metabolic stress mitochondral quality control mitophagy PINK1 tumor Warburg effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Giant enhancement of superconductivity in few layers MoTe2

引用

Chinese Physics B 2019年第11期28卷 79-83页

作者： Yuan Gan Chang-Woo Cho Alei Li Jian Lyu Xu Du Jin-Sheng Wen Li-Yuan Zhang National Laboratory of Solid State Microstructures and department of Physics Nanjing UniversityNanjing 210093China department of Physics Southern University of Science and TechnologyShenzhen 518055China department of Physics and Astronomy Stony Brook UniversityStony BrookNY 11794USA

Recently, the layered transition metal dichalcogenide 1 T MoTe2 has attracted considerable attention due to its non-saturating magnetoresistance, type-II Weyl semimetal properties, superconductivity, and potential candidate for twodimensional（2 D） topological insulator in the single-and few-layer limit. Here in this work, we perform systematic transport measurements on thin flakes of MoTe2 prepared by mechanical exfoliation. We find that MoTe2 flakes are superconducting and have an onset superconducting transition temperature Tc up to 5.3 K, which significantly exceeds that of its bulk counterpart. The in-plane upper critical field(Hc2||) is much higher than the Pauli paramagnetic limit, implying that the MoTe2 flakes have Zeeman-protected Ising superconductivity. Furthermore, the Tc and Hc2|| can be tuned by up to 320 mK and 400 mT by applying a gate voltage. Our result indicates that MoTe2 flake is a good candidate for studying exotic superconductivity with nontrivial topological properties.

关键词： transition metal dichalcogenide Weyl semimetal Ising superconductivity magneto-transport

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Item Response Theory Based Ensemble in Machine Learning

引用

International Journal of Automation and computing 2020年第5期17卷 621-636页

作者： Ziheng Chen Hongshik Ahn department of Applied Mathematics and Statistics Stony Brook UniversityNew York 11794−3600USA

In this article,we propose a novel probabilistic framework to improve the accuracy of a weighted majority voting *** order to assign higher weights to the classifiers which can correctly classify hard-to-classify instances,we introduce the item response theory(IRT)framework to evaluate the samples′difficulty and classifiers′ability *** assigned the weights to classifiers based on their *** models are created with different assumptions suitable for different *** making an inference,we keep a balance between the accuracy and *** our experiment,all the base models are constructed by single trees via *** explain the models,we illustrate how the IRT ensemble model constructs the classifying *** also compare their performance with other widely used methods and show that our model performs well on 19 datasets.

关键词： Classification ensemble learning item response theory machine learning expectation maximization(EM)algorithm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：