Interactions Between Extracellular Vesicles and Autophagy in Neuroimmune Disorders

作     者：Xiwen Ai Haojun Yu Yu Cai Yangtai Guan 

作者机构：Department of NeurologyShanghai Jiao Tong University School of Medicine Affiliated Renji HospitalShanghai 200127China Department of NeurologyRenaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2024年第40卷第7期

页      面：992-1006页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the National Key Research and Development Project of Stem Cell and Translational Research by the Ministry of Science and Technology(2020YFA0113100) Innovative Research Team of High-Level Local Universities in Shanghai(SHSMU-ZDCX20211901) the National Natural Science Foundation of China(82071341) the Key Projects of Basic Research of Shanghai Municipal Science and Technology Commission(20JC1412000) 

主　　题：Autophagy Extracellular vesicles Neuroimmune disorders Multiple sclerosis Neuromyelitis optica spectrum disorder Myasthenia gravis Guillain-Barré syndrome 

摘      要：Neuroimmune disorders,such as multiple sclerosis,neuromyelitis optica spectrum disorder,myasthenia gravis,and Guillain–Barrésyndrome,are characterized by the dysfunction of both the immune system and the nervous *** evidence suggests that extracellular vesicles and autophagy are closely associated with the pathogenesis of these *** this review,we summarize the current understanding of the interactions between extracellular vesicles and autophagy in neuroimmune disorders and discuss their potential diagnostic and therapeutic *** we highlight the need for further research to fully understand the mechanisms underlying these disorders,and to develop new diagnostic and therapeutic strategies.