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HCV-specific immune responses induced by CIGB-230 in combination with IFn-α plus ribavirin

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World Journal of Gastroenterology 2014年第1期20卷 148-162页

作者： yalena Amador-Caizares Gillian Martínez-Donato Liz lvarez-Lajonchere Claudia Vasallo Mariacarla Dausá Daylen Aguilar-noriega Carmen Valenzuela Ivette Raíces Jean Dubuisson Czeslaw Wychowski Zurina Cinza-Estévez Marlén Castellanos Magdalys núez Anny Armas yaimé González Ismariley Revé Ivis Guerra ngel Pérez Aguiar Santiago Dueas-Carrera centro de ingeniería Genética y Biotecnología Playa 10600HavanaCuba Center for Infection and Immunity of Lille (CIIL) Inserm U1019CNRS UMR8204Institut Pasteur de LilleUniv Lille Nord de FranceF-59000 LilleFrance Instituto de Gastroenterología Vedado 10400HavanaCuba Hospital Clínico Quirúrgico "Hermanos Amejeiras" Havana 10200Cuba centro de Inmunoensayos Havana 11300Cuba

AIM: To analyze hepatitis C virus (HCV)-specific immune responses in chronically infected patients under triple therapy with interferon-α (IFn-α) plus ribavirin and CIGB-230.

关键词： Clinical trial DnA vaccine Enzyme-linked immunospot Hepatitis C virus Leukopenia

Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats

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Food Science and Human Wellness 2023年第6期12卷 2022-2028页

作者： Maria Rosana Ramirez debora Manuale Juan Carlos yori Instituto Universitario de ciencias de la Salud Fundación BarcelóCONICETCenteno 710CP 3340Santo TomeCorrientesArgentina Consejo nacional de investigaciones Científi cas Técnicas(COnICET) Buenos Aires C1033AAJArgentina Instituto de investigaciones en Catálisis y Petroquímica(InCAPE)FIQ-UnL-COnICET Parque Tecnológico Litoral Centro 3000Santa FeArgentina Facultad de ingeniería Química Universidad nacional del Litoral 3000Santa FeArgentina

This present study was conducted to evaluate the metabolic effects of isolated fi ber of carrot supplementation in *** properties of fi ber were *** groups were as follows:animals fed a standard diet,control group;high fi ber supplementation(70 mg);low fi ber supplementation(35 mg);for 12 *** samples were collected at the time of sacrifi *** weights of heart,liver,kidneys and spleen of the experimental rats with respect to body weight were *** kits were used to determine serum glucose concentration,lipid profi le(cholesterol,HDL-cholesterol,triglycerides),and the two main aminotransferases glutamic-oxalacetic transaminase(GOT)/glutamate-pyruvate transaminase(GPT).A histopathological assay was performed on the heart,liver,and spleen tissues of *** with fi ber favors weight loss in female((242.03±23.73)-(197.81±10.45)g);and male rats((262.50±32.21)-(213.96±12.56)g and induces a decrease in glucose levels in the supplemented *** the exception of total high-density lipoprotein cholesterol,the other lipid fractions decrease signifi cantly in rats *** supplementation did not induce changes in the dissected organs of the supplemented *** conclusion supplementation of fiber,improves glucose control,lower plasma lipid concentrations and reduced body weight in normal rats.

关键词： Carrot fiber Oral supplementation Animal studies

环太平洋特大干旱导致公元1644年明朝首都的陷落（英文）

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Science Bulletin 2024年第19期 3106-3114页

作者：陈峰王涛赵晓恩 Jan Esper Fredrik Charpentier Ljungqvist Ulf Büntgen Hans W.Linderholm David Meko 许红娜岳伟鹏王世杰袁玉江郑景云潘威 Fidel Roig Martín Hadad 胡茂魏家昌陈发虎 yunnan Key Laboratory of International Rivers and Transboundary Eco-Security Institute of International Rivers and Eco-Security Yunnan University Southwest United Graduate School Regional Climate Group Department of Earth Sciences University of Gothenburg Climate Change Research Center and nansen-Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of Sciences department of Geography Johannes Gutenberg University Global Change Research Institute (Czech Globe) Czech Academy of Sciences department of History Stockholm University Bolin Centre for Climate Research Stockholm University Swedish Collegium for Advanced Study Linneanum department of Geography University of Cambridge department of Geography Faculty of Science Masaryk University Swiss Federal Research Institute (WSL) Laboratory of Tree-Ring Research University of Arizona Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters (CIC FEMD) Nanjing University of Information Science and Technology Key Laboratory of Tree-ring Physical and Chemical Research Institute of Desert Meteorology China Meteorological Administration Key Laboratory of Land Surface Pattern and Simulation Institute of Geographical Sciences and Natural Resources Research Chinese Academy of Sciences Key Laboratory of Digital Human Technology R&D and Application of yunnan Provincial department of Education Yunnan University Laboratorio de dendrocronología e Historia Ambiental IANIGLA-CCT CONICET-Universidad Nacional de Cuyo Hémera centro de Observación de La Tierra Escuela de Ingeniería Forestal Facultad de Ciencias Universidad Mayor Laboratorio de dendrocronología de Zonas áridas CIGEOBIO (COnICET-UnSJ) Gabinete de Geología Ambiental (INGEO-UNSJ) ALPHA State Key Laboratory of Tibetan Plateau Earth System Environment and Resources (TPESER) Institute of Tibetan Plateau Research Chinese Academy of Sciences College of Resources and Environment University of Chinese Academy of Sciences MOE Key Laboratory of We

Historical documents provide evidence for regional droughts preceding the political turmoil and fall of Beijing in 1644 CE, when more than 20 million people died in northern China during the late Ming famine period. However, the role climate and environmental changes may have played in this pivotal event in Chinese history remains unclear. Here, we provide tree-ring evidence of persistent megadroughts from1576 to 1593 CE and from 1628 to 1644 CE in northern China, which coincided with exceptionally cold summers just before the fall of Beijing. Our analysis reveals that these regional hydroclimatic extremes are part of a series of megadroughts along the Pacific Rim, which not only impacted the ecology and society of monsoonal northern China, but likely also exacerbated external geopolitical and economic pressures. This finding is corroborated by last millennium reanalysis data and numerical climate model simulations revealing internally driven Pacific sea surface temperature variations and the predominance of decadal scale La ni?a-like conditions to be responsible for precipitation decreases over northern China,as well as extensive monsoon regions in the Americas. These teleconnection patterns provide a mechanistic explanation for reoccurring drought spells during the late Ming Dynasty and the environmental framework fostering the fall of Beijing in 1644 CE, and the subsequent demise of the Ming Dynasty.

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Environmental Impact Assessment for an Absorption Heat Transformer

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Open Journal of Applied Sciences 2016年第7期6卷 409-415页

作者： Jorge Avelino Domínguez Patiño Antonio Rodríguez Martínez Rosenberg Javier Romero Jonathan Ibarra-Bahena Martha Lilia Domínguez Patiño FCQeI (Facultad de ciencias Químicas e ingeniería) Universidad Autónoma del Estado de Morelos Cuernavaca México CIICAp (centro de investigación en ingeniería y ciencias aplicadas) Universidad Autónoma del Estado de Morelos Cuernavaca México

This study presents the environmental impact assessment of an absorption heat transformer designed to recover 1 kW of thermal energy from each 2 kW of waste heat supplies. The net contribution of the heat transformer is a load avoided of 0.665 kg CO2 equivalents;the recovery process avoids 0.729 kg CO2 equivalents and the major contribution to the environment impacts is the pumping process with 0.0437 kg CO2 equivalents for each 1 kWh recovered. The study results show that absorption heat transformer is a good environmental option because it produces useful energy from waste heat and the final result is an environmental impact diminution.

关键词： Environmental Impact Life Cycle Assessment LCA Absorption Heat Transformer Waste Heat Recovery

Recycling Agave Bagasse of the Tequila Industry

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Advances in Chemical Engineering and Science 2014年第2期4卷 135-142页

作者： C.G.Iniguez C.J.J.Bernal M.W.Ramírez n.J.Villalvazo departamento de Madera Celulosa y PapelCentro Universitario de Ciencias Exactas e IngenieríasUniversidad de GuadalajaraGuadalajaraMéxico departamento de ingeniería de Proyectos Centro Universitario de Ciencias Exactas e IngenieríasUniversidad de GuadalajaraGuadalajaraMéxico

This paper presents an overview of different handling systems and use of the agave bagasse. These systems have appeared from different research works always taking in account the environmental sustainability. It is mentioned that the agave bagasse can be used for animal feeding, for the elaboration of compound materials, as an element for agricultural and hydroponic vegetables cultivation purposes, and also as a means to treat biosolids, vinasses, and bagasses of slaughterhouses and tanneries.

关键词： Agave Bagasse Tequila Vinasses Tequila

Electrochemical and Photoelectrochemical decoloration of Amaranth Dye Azo Using Composited Dimensional Stable Anodes

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Journal of Environmental Protection 2013年第1期4卷 136-143页

作者： Moisés I. Salazar-Gastélum Edgar A. Reynoso-Soto Shui W. Lin Sergio Perez-Sicairos Rosa M. Félix-navarro ingeniería en nanotecnología Centro de Graduados e Investigación en Química del Instituto Tecnológico de Tijuana Tijuana México

In this paper we report the results of our experimental work conducted to decoloration of a well-known highly toxic Amaranth dye by electrochemical and photoelectrochemical methods. Throughout this investigation were used two different Dimensional Stable Anode (DSA) electrodes, namely, IrO2-Ru2O-SnO2-TiO2/Ti and Ru2O-SnO2-TiO2/Ti. The experimental results show that IrO2-Ru2O-SnO2-TiO2/Ti electrode has higher performance on amaranth decoloration than Ru2O-SnO2-TiO2/Ti electrode, but with the disadvantage of higher energy consumption. For higher degradation of Amaranth dye with both DSA electrodes, the process was carried out via photoelectrochemical method. Our experimental results clearly shown the decrease in absorbance of all UV-Vis peaks due to the mineralization of the azo dye;also, it was noteworthy photoelectrochemical process consumes less energy under the same experimental conditions than electrochemical process. The IrO2-Ru2O-SnO2-TiO2/Ti electrode reaches a higher degradation degree of Amaranth solutions than Ru2O-SnO2-TiO2/Ti electrode using a photoelectrochemical technique.

关键词： Photoelectrochemical decoloration DSA Azo Amaranth Dye

Identification of quantitative trait loci and candidate genes for primary metabolite content in strawberry fruit

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Horticulture Research 2019年第1期6卷 1638-1654页

作者： JoséG.Vallarino delphine M.Pott Eduardo Cruz-Rus Luis Miranda Juan J.Medina-Minguez Victoriano Valpuesta Alisdair R.Fernie JoséF.Sánchez-Sevilla Sonia Osorio Iraida Amaya department of Molecular Biology and Biochemistry Instituto de Hortofruticultura Subtropical y Mediterránea“La Mayora”University of Málaga–Consejo Superior de Investigaciones Científicas(IHSM-UMA-CSIC)Campus de Teatinos29071 MálagaSpain Max-Planck-Institut für Molekulare Pflanzenphysiologie Am Mühlenberg 114476 Potsdam-GolmGermany Genómica y Biotecnología Centro de MálagaInstituto Andaluz de Investigación y Formación Agraria y Pesquera(IFAPA)29140 MálagaSpain ingeniería y Tecnología Agroalimentaria Centro Las Torres-TomejilInstituto Andaluz de Investigación y Formación Agraria y Pesquera(IFAPA)Alcaládel RíoSevillaSpain ingeniería y Tecnología Agroalimentaria Centro de HuelvaInstituto Andaluz de Investigación y Formación Agraria y Pesquera(IFAPA)HuelvaSpain

Improvement of nutritional and organoleptic quality of fruits is a key goal in current strawberry breeding *** ratio of sugars to acids is a determinant factor contributing to fruit liking,although different sugars and acids contribute in varying degrees to this complex trait.A segregating F1 population of 95 individuals,previously characterized for several fruit quality characters,was used to map during 2 years quantitative trait loci(QTL)for 50 primary metabolites,L-ascorbic acid(L-AA)and other related traits such as soluble solid content(SSC),titratable acidity(TA),and pH.A total of 133 mQTL were detected above the established thresholds for 44 *** 12.9%of QTL were detected in the 2 years,suggesting a large environmental influence on primary metabolite *** objective of this study was the identification of key metabolites that were associated to the overall variation in SSC and *** it was observed in previous studies,a number of QTL controlling several metabolites and traits were co-located in homoeology group V(HG V).mQTL controlling a large variance in raffinose,sucrose,succinic acid,and L-AA were detected in approximate the same chromosomal regions of different homoeologous linkage groups belonging to HG *** genes for selected mQTL are proposed based on their co-localization,on the predicted function,and their differential gene expression among contrasting F1 progeny ***-seq analysis from progeny lines contrasting in L-AA content detected 826 differentially expressed genes and identified Mannose-6-phosphate isomerase,FaM6PI1,as a candidate gene contributing to natural variation in ascorbic acid in strawberry fruit.

关键词： straw breeding trait

Identifiability and Stability of an Inverse Problem Involving a Fredholm Equation

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Chinese Annals of Mathematics,Series B 2015年第5期36卷 737-762页

作者： Carlos COnCA Rodrigo LECAROS Jaime H.ORTEGA Lionel ROSIER centro de Modelamiento Matematico and departamento de ingenier?a Matematica Universidad de Chile (UMI CNRS 2807) Avda Beauchef 851 Edificio Norte Casilla 170-3 Correo 3 Santiago 8370459Chile Centre Automatique et Systemes MINES Paris Tech PSL Research University

The authors study a linear inverse problem with a biological interpretation,which is modelled by a Fredholm integral equation of the first kind, where the kernel is represented by step functions. Based on different as... 详细信息

关键词： Inverse problems Olfactory system Kernel determination Fredholm integral equation Partial differential equations numerical reconstruction

Optical determination of the Effects by Thermal Treatment(TT)in Honey of Apis mellifera Bees

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Journal of Agricultural Chemistry and Environment 2020年第2期9卷 37-47页

作者： Pablo Broca Quevedo Miguel Angel Basurto Pensado R.J.Romero Antonio Rodríguez Martínez Graduate degree in Engineering and Applied Science Instituto de Investigación en Ciencias Básicas y Aplicadas(ICCBA)Universidad Autónoma Del Estado De Morelos(UAEM)MorelosMéxico centro de investigación en ingeniería y ciencias aplicadas(CIICAp) Universidad Autónoma Del Estado De Morelos(UAEM)MorelosMéxico

Spectroscopy in the UV-Vis and nIR ranges of light provides great convenience for the characterization and evaluation of the characteristics and optical modifications that occur during life, the processes for the preparation of some food in order to modify their characteristics or eliminate Micro-organisms that can affect their quality and shelf life, work is carried out at elevated temperatures, even above 100°C. The study has made it possible to identify changes in the Absorbance, Transmittance and Optical Intensity of Apis mellifera honey from four different botanical sources and States of the Mexican Republic: Citrus (Citrus) from the state of Veracruz, Mangle (Rizophora mangle) of the Pacific zone of the state of Sinaloa, Polyfloralis of the state of Morelos and Polyfloralis of the state of Tabasco.

关键词： Heat Treatment Spectroscopy Food Conservation Honey