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When the Silence Speaks: The Smile

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Journal of Biosciences and Medicines 2018年第11期6卷 13-20页

作者： Maria do Rosário Dias Letícia Garcia Naben Ana Lúcia Monteiro Ana Ferreira Valter Pedroso Alves Ana delgado Unidade de Investigaç &atilde o-centro de Investigaç &atilde o Multidisciplinar em Psicologia da Saúde Egas Moniz (ciMPSem) Egas Moniz-Cooperativa de Ensino Superior Monte de Caparica Portugal

Background: Understanding the importance, value and self-image that the smile represents in the daily life of the individual remains a subject of high scientific interest. Aim: The present qualitative and exploratory study aims at understanding the importance of the self-perception of the mouth and smile on the mental representation of self-image and the well-being of the individual. Materials and Methods: The convenience sample consisted of 151 children and youngsters of both genders, ages 8 - 24 years, who used an orthodontic appliance and were invited to draw two portraits of their mouth/smile. Results: The results suggest differences in the mental representation of the mouth and the smile, namely in the investment of the drawings before and after the use of the orthodontic appliance, as well as in the expressiveness and manifestation of emotions. Discussion and Conclusions: The results suggest that the main reason that leads participants to the treatment is related to aesthetic and functional issues in which the maximizing of the mental representation of the orthodontic Smile emerges as a new categorization of the perfect smile.

关键词： Mental Representation orthodontic Smile Aesthetic Smile Drawing Content Analysis

Farming-Biodiversity Segregation or Integration? Revisiting Land Sparing versus Land Sharing debate

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Journal of Environmental Protection 2016年第7期7卷 1016-1032页

作者： Fernando F. Goulart Sonia Carvalho-Ribeiro Britaldo Soares-Filho centro de Sensoriamento Remoto Mestrado em Análise e Modelagem de Sistemas Ambientais Departamento de Cartografia Instituto de Geociências Universidade Federal de Minas Gerais Belo Horizonte Brazil

Land Sparing (LSP) was proposed to spatially segregate biodiversity and production in order to maximize both, while Land Sharing (LSH) defenders posit that farming and nature integration is preferable, through eco-agriculture and low-input systems. Based on a multidisciplinary review on historical land-use data, ecological aspects, agricultural production potential, economic and food security topics, we summarize LSP/LSH major findings and caveats. Although LSH still has to address some issues, LSP relies on a series of assumptions that are not supported by data, particularly regarding the positive effects of intensification on agriculture expansion. Furthermore, we developed conceptual models to theoretically predict the responses of biodiversity and ecosystems services in dynamic landscapes with different natural habitat proportions and different intensification levels on the farmed areas. Agriculture intensification may expand farmland reducing habitat area fostering population declines at the “natural” patches (via habitat reduction and decreasing species intra patch flux through the matrix), as well as at the farm site by direct effect of intensification (heterogeneity reduction and pesticide use), leading to a species extinction and ecosystems services loss. This multiple negative effect of agriculture intensification is worsening in regions where habitat proportion is below 30%, such as in many tropical biodiversity hotspots, making LSH a much safer strategy for conservation and food security.

关键词： Agriculture Intensification Biodiversity Conservation Forest Transition Food Security Jevons Paradox Tropics

Trypanosoma cruzi invasion in non-phagocytic cells:an ultrastructural study

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BIoCELL 2018年第3期42卷 105-108页

作者： Juan Agustín CUETo emile SANToS BARRIAS Wanderley de SoUZA Patricia Silvia RoMANo IHem Universidad Nacional de CuyoCONICETLaboratorio de Biología de Tripanosoma cruzi y de la célula hospedadoraMendozaArgentina Universidad Nacional de Cuyo.Facultad de ciencias Médicas.Área de Biología Celular y Molecular.Mendoza.Argentina Universidad Nacional de Cuyo.Facultad de ciencias Médicas.Instituto de Fisiología.Mendoza.Argentina Laboratório de Ultraestrutura Celular Hertha Meyer Instituto de Biofísica Carlos Chagas FilhoCentro de Ciência da SaúdeUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto Nacional de ciência e Tecnologia em Biologia Estrutural e Bioimagens e centro Nacional de Bioimagens-CENABIo Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto Nacional de Metrologia Qualidade e Tecnologia-InmetroRio de JaneiroBrazil

Trypanosoma cruzi is the causative agent of Chagas *** parasite requires the intracellular niche in order to proliferate and disseminate the *** invasion,*** resides temporarily in an acidic vacuole which is lysed by a not well-understood *** electron microscopy was used to describe the process of *** escape from the parasitophorous vacuole over the *** HeLa(non-professional phagocytic cells)as host cell,we observed that recently internalized parasites reside in a membrane-bounded vacuole.A few hours later,the first sign of vacuole disruption appeared as membrane *** observation was followed by a progressive vacuole swelling as evidenced by an electron-lucent halo between the parasite and the vacuole ***,the vacuole membrane remnants reorganized as small vesicles that eventually disappeared from the vicinity of the ***,parasites reach the host cell cytosol where replication takes *** thorough ultrastructural description of this process set the base for a comprehensive understanding of the parasite-host cell interaction and,thus open the possibility of new therapeutic intervention strategies.

关键词： Parasitophorous vacuole Pathogen Parasites Chagas disease Infectious diseases

New Formulation for Semi-empirical Correlations for Penetration Jets

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World Journal of Nuclear Science and Technology 2019年第2期9卷 96-111页

作者： R. R. Pacheco L. o. Freire M. S. Rocha N. L. Scuro M. o. Menezes D. A. Andrade centro Tecnológico da Marinha em S&atilde o Paulo S&atilde o Paulo Brazil Instituto de Pesquisas Energéticas e Nucleares S&atilde o Paulo Brazil

Correlations for the extension of a water vapor jet injected in a liquid pool were historically proposed considering the mass flux (kg/m2/s) as a constant. The results were satisfactory, however adjusting the values by linear regression. Although, it presents the following drawbacks: 1) the formulation is only valid for the specific range of data for what it was created;2) it does not allow the analytical evaluation of the heat transfer coefficient from the extension equation. This paper proposes a new formulation for the calculation of the mass flux, in such a way to remove both of these drawbacks.

关键词： Direct Contact Condensation Vapor Jet Steam Jet Steam Mass Flux Vapor Cavity Reynolds Number Jet Radius Rate of Condensation Non-Dimensional Jet Length Liquid Pool Dimensionless Transport Modulus Condensation Driving Potential

Evaluation of Physical and Mental Quality of Life of Motorcycle Taxi Drivers

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Journal of Biosciences and Medicines 2016年第3期4卷 69-74页

作者： Arlete de Carvalho Félix Alexandra Maria Almeida Carvalho Pinto Albert Schiaveto de Souza departamento do Programa de Pós-Graduaç &atilde o em Saúde e desenvolvimento na Regi&atilde o centro oeste Campo Grande Mato Grosso do Sul Brasil

Motorcycle taxi drivers are workers who use motorcycle to carry passengers. objectives: to identify the sociodemographic profile and evaluate the physical and mental quality of life of motorcycle taxi drivers. Methods: Cross-sectional study, held in Campo Grande, Mato Grosso do Sul-Brazil, from May to July 2015 with 301 participants. To calculate the sample size, the margin of error was 5%, confidence level, 95%;and the drivers were randomly selected. For data collection, two instruments were used: the demographic questionnaire and the SF-36 Health Status Questionnaire. Results: Among the 301 respondents, predominance fell on males (98.7%, n = 297), married or in a stable relationship (63.5%, n = 191), with completed high school education (44.9%, n = 135). More than half felt discomfort while working (52.8%, n = 159). of those with diagnosed disease the predominant type of disease was hypertension (55.5%, n = 30). When male and female were compared, men had lower average in the mental health aspect (63.39 ± 13.22);and women, in the emotional aspect (41.66 ± 31.91). There were significant differences in the scores of physical functioning (p = 0.002), bodily pain (0.043) and general health perceptions (p = 0.003) of the drivers reporting disease, compared to those who did not reported it. Conclusion: The studied motorcycle taxi drivers are mostly male, married, with high school education. Regarding quality of life, men had lower perception in the general mental health aspect whereas women showed lower perception in the emotional aspects. The individuals with disease had lower perceived quality of life in the physical functioning, bodily pain and general health concepts.

关键词： Disease Motorcycle Taxi Drivers Quality of Life

Kinetics and thermodynamic studies of Methyl orange removal by polyvinylidene fluoride-PEDoT mats

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Journal of Environmental Sciences 2021年第2期33卷 62-73页

作者： Romario J.da Silva Lizeth Carolina Mojica-Sanchez Filipe D.S.Gorza Graciela C.Pedro Bruna G.Maciel Gabriela P.Ratkovski Herica D.daRocha Kamila T.o.do Nascimento Juan CMedina-Llamas Alicia E.Chavez-Guajardo Jose J.Alcaraz-Espinoza Celso P.de Melo Program a de Pos-Graduagao em ciencia de Materials U niversidade Federal de Pernambuco50670-901 RecifePEBrazil departamento de Ffsica Uniuersidade Federal de Pemambiico50670-901 Reci/ePEBrazil centro de Estudios cientificosy Tecnologicos No.18 Instituto Politecnico Nacional98160 ZacatecasZacMexico Unidad Academica de ciencias de la Tierra Uniuersidad Aut6noma de Zacatecas98058 ZacatecasZacMexico departamento de Quimica Universidad Autonoma Metropolitana09340Ciudad de MexicoMexico

We report the preparation of poly(3,4-ethylene dioxythiophene)(PEDoT)-modified polyvinylidene fluoride electrospun fibers and their use as a novel adsorbent material for the removal of the anionic dye Methyl orange(Mo)from aqueous *** novel adsorbent material can be used to selectively remove Mo on a wide p H range(3.0-10.0),with a maximum capacity of 143.8 mg/g at p H *** used in a recirculating filtration system,the maximum absorption capacity was reached in a shorter time(20 min)than that observed for batch mode experiments(360 min).Based on the analyses of the kinetics and adsorption isotherm data,one can conclude that the predominant mechanism of interaction between the membrane and the dissolved dye molecules is ***,considering the estimated values for the Gibbs energy,and entropy and enthalpy changes,it was established that the adsorption process is spontaneous and occurs in an endothermic *** good mechanical and environmental stability of these membranes allowed their use in at least 20 consecutive adsorption/desorption cycles,without significant loss of their *** suggest that the physical-chemical characteristics of PEDoT make these hybrid mats a promising adsorbent material for use in water remediation protocols and effluent treatment systems.

关键词： Electrospinning Composite mats Pedot Pvdf mats Dye removal Water remediation

“Stop Ne(c)king around”: How interactomics contributes to functionally characterize Nek family kinases

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World Journal of Biological Chemistry 2014年第2期5卷 141-160页

作者： Gabriela Vaz Meirelles Arina Marina Perez Edmárcia Elisa de Souza Ferna Luisa Basei Priscila Ferreira Papa Talita Diniz Melo Hanchuk Vanessa Bomfim Cardoso Jrg Kobarg Laboratório Nacional de Biociências Centro Nacional de Pesquisa em Energia e Materiais Campinas SP 13084-971Brazil departamento de Bioquímica-Programa de Pós-gradua o em Biologia Funcional e Molecular Instituto de Biologia Universidade Estadual de Campinas Campinas SP 13084-971 Brasil departamento de Genética Evolu o e Bioagentes-Programa de Pós-gradua o em Genética e Biologia Molecular Instituto de Biologia Universidade Estadual de Campinas1 Campinas SP 13084-97 Brasil

Aside from Polo and Aurora, a third but less studied kinase family involved in mitosis regulation is the never in mitosis-gene A(NIMA)-related kinases(Neks). The founding member of this family is the sole member NIMA of Aspergillus nidulans, which is crucial for the initiation of mitosis in that organism. All 11 human Neks have been functionally assigned to one of the three core functions established for this family in mammals:(1) centrioles/mitosis;(2) primary ciliary function/ciliopathies; and(3) DNA damage response(DDR). Recent findings, especially on Nek 1 and 8, showed however, that several Neks participate in parallel in at least two of these contexts: primary ciliary function and DDR. In the core section of this in-depth review, we report the current detailed functional knowledge on each of the 11 Neks. In the discussion, we return to the cross-connections among Neks and point out how our and other groups' functional and interactomics studies revealed that most Neks interact with protein partners associated with two if not all three of the functional contexts. We then raise the hypothesis that Neks may be the connecting regulatory elements that allow the cell to fine tune and synchronize the cellular events associated with these three core functions. The new and exciting findings on the Nek family open new perspectives and should allow the Neks to finally claim the attention they deserve in the field of kinases and cell cycle biology.

关键词： Cell cycle Mitosis DNA damage response Protein interactions Kinases

Editorial:Functional foods processing and preservation

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Food Bioscience 2023年第3期53卷 1-3页

作者： José Pinela Carla Pereira Maria Inês Dias Lillian Barros centro de Investigaçāo de Montanha(ciMo) Instituto Politécnico de BragançaCampus de Santa Apolónia5300-253BragançaPortugal Laboratório Associado para a Sustentabilidade e Tecnologia em Regiōes de Montanha(SusTEC)Instituto Politécnico de BragançaCampus de Santa Apolónia5300-253BragançaPortugal

*** Functional foods have a nutritive value and appearance similar to conventional foods,but they bring additional health-promoting effects and/or disease-preventing capabilities when consumed as part of a varied daily *** can occur naturally or be developed through processing or agro-biotechnological ***,modified or not,they must always be safe,without any consideration of a trade-off between health benefit and health risk(Pinela et al.,2016).Nowadays,processing and preserving functional foods,whether solid or liquid,is a major scientific challenge since the factors involved can lead to the degradation of micronutrients and bioactive compounds and affect physicochemical parameters.

关键词： Functional preserving processing

Artisanal ceramic factories using wood combustion:A nanoparticles and human health study

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Geoscience Frontiers 2022年第1期13卷 488-497页

作者： Kátia Martinello James C.Hower Diana Pinto Carlos E.Schnorr Guilherme L.Dotto Marcos Leandro Silva oliveira Claudete G.Ramos Instituto Inanís Rua Felizardo FurtadoPorto AlegreBrazil department of civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia University of Kentucky Department of Earth&Environmental SciencesLexingtonKY 40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY 40511USA centro de Estudos em Estresse oxidativo-departamento de Bioquímica-Instituto de ciências Básicas da Saúde-Universidade Federal do Rio Grande do Sul(UFRGS) Porto AlegreRSBrazil Chemical Engineering department Federal University of Santa MariaUFSMRoraima Avenue1000Santa MariaRS97105-900Brazil departamento de Ingeniería civil y Arquitectura Universidad de LimaAvenida Javier Prado Este 4600–Santiago de Surco 1503Peru

The ceramics industry,resulting from developments of modern compounds,is a segment of great influence in worldwide *** ceramic factories based on wood combustion have significant risks for the creation and discharge of atmosphere nanoparticles(NPs)and ultra-fine particles(UFPs).At present,there is insufficient recognition on the influence of engineered-NPs on the atmosphere and *** improvements are indispensable to diminish contact with *** present study demonstrates the main NPs and UFPS present in an area of intense artisanal wood-combustion ceramic *** matter was sampled for morphological,chemical,and geochemical studies by sophisticated electron microbeam microscopy,X-Ray Diffraction,and Raman *** NPs configuration(dentify *** amorphous NPs(>10 nm)were produced around the studied artisanal ceramic *** study presents an indication of the recent information on population and work-related contact to NPs in the artisanal ceramic factories and their influence on health.

关键词： Ceramic manufacturing Nanoparticles Advanced characterization Multiple impacts