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Radiotherapy-customized head immobilization masks:from modeling and analysis to 3D printing

Nuclear Science and Techniques 2019年第9期30卷 103-118页

作者： M.A.R.Loja D.S.Craveiro L.Vieira e.Sousa J.A.Rodrigues R.J.F.Portal ciMOSM Centro de Investigacao em Modelacao e Optimizacao de Sistemas Multifuncionais ISEL IPL Instituto Superior de Engenharia de Lisboa Av. Conselheiro Emidio Navarro 1 1959-007 Lisbon Portugal LAeTA IDMEC Instituto Superior Teccnico Universidade de Lisboa Av. Rovisco Pais 1 1049-001 Lisbon Portugal department of Mechanical and Industrial engineering Faculty of Science and Technology NOVA UNIDEMI Universidade Nova de Lisboa Caparica Portugal H&TRC -Health &Technology Research Center ESTeSL - Escola Superior de Tecnologia da Saude de Lisboa Av. D. Joao II Lote 4.69.01 1990-096 Lisbon Portugal Instituto de Biofisica e engenharia Biomedica Faculdade de Ciencias da Universidade de Lisboa Lisbon Portugal

Immobilization devices may be a valuable aid to ensure the improved effectiveness of radiotherapy treatments where constraining the movements of specific anatomical segments is crucial. This need is also present in other situations, specifically when the superposition of various medical images is required for fine identification and characterization of some pathologies. Because of their structural characteristics, existing head immobilization systems may be claustrophobic and very uncomfortable for patients, during both the modeling and usage stages. Because of this, it is important to minimize all the discomforts related to the mask to alleviate patients’ distress and to simultaneously guarantee and maximize the restraint effectiveness of the mask. In the present work, various head immobilization mask models are proposed based on geometrical information extracted from computerized tomography images and from 3D laser scanning point clouds. These models also consider the corresponding connection to a radiotherapy table, as this connection is easily altered to accommodate various manufacturers’ solutions. A set of materials used in the radiotherapy field is considered to allow the assessment of the stiffness and strength of the masks when submitted to typical loadings.

关键词： Computed tomography 3D laser scanning Geometric modeling Head immobilization devices Stiffness and strength analyses 3D printing

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Contrasting soil fungal communities in Mediterranean pine forests subjected to different wildfire frequencies

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Fungal Diversity 2015年第1期70卷 85-99页

作者： erika Buscardo Susana Rodríguez-echeverría Helena Freitas Paolo de Angelis João Santos Pereira Ludo A.H.Muller centro de ecologia Funcional(CeF) Departamento de Ciências da VidaUniversidade de CoimbraCalçada Martim de Freitas3000-456 CoimbraPortugal department for Innovation in Biological Agro-Food and Forest Systems(DIBAF)University of TusciaVia S.Camillo de Lellis snc01100 ViterboItaly escritório Central do LBA Instituto Nacional de Pesquisa da Amazônia(INPA)Av.AndréAraújo2936Campus IIAleixo69060-001 ManausAmazonasBrazil departamento de engenharia Florestal Instituto Superior de AgronomiaUniversidade Técnica de LisboaTapada da Ajuda1349-018 LisbonPortugal Institut für Biologie—Botanik Freie Universität BerlinAltensteinstrasse 614195 BerlinGermany

Mediterranean forest ecosystems are characterized by various vascular plant groups with their associated mycor-rhizae and free living soil fungi with various ecological *** plays a major role in Mediterranean ecosystem dynamics and impacts both above-and below-ground community structure and ***,studies on the effects induced by altered disturbance regimes(associated with recent land use and climate extremes)on fire ecology and especially on its below-ground impacts are *** objectives of this study were to evaluate the effects of different wildfire regimes on soil fungal community structure using two different molecular *** investigated the long-term effects of wildfire on soil fungal communities associated with Pinus pinaster forests in central Portugal,by comparing the results of denaturing gradient gel electrophoresis(DGGe)-based profiling with those obtained with 454 *** forest stands with differing fire history and fire return interval,and vegetation cover(mature forest,early successional stage of pine regeneration,and forest converted to scrubland)were sampled 6 years after the last fire *** pyrosequencing-based approach indicated ***-fold higher numbers of taxa than ***,fungal community fingerprinting data obtained for the different study stands with DGGe were congruent with those obtained with *** short(7.6 years)and long(24 years)fire return intervals(indicated by the presence of ericaceous shrubs in the understorey)induced a decrease in the abun-dance ratio between basidiomycetes and ascomycetes and appeared to reduce the frequency of ectomycorrhizal fungal species and *** significantly reduced the frequency of late stage successional taxa(*** and Cantharellales)and known or putative saprophytes belonging to the Clavulinaceae and the ***,early successional fungal species belonging to the Thelephoraceae were fav

关键词： 454 Pyrosequencing DGGe Wildfire frequency Soil fungal community Maritime pine

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The Fertilizer-effect on Al, Ba, Fe, Mn and Ni Released in a Watershed with Influence of Sugar Cane Crops in the São Paulo State, Brazil

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Journal of Water Resource and Protection 2019年第5期11卷 638-650页

作者： eder Paulo Spatti Jú nior Fabiano Tomazini da Conceiç o Amauri Antonio Menegá rio Alexandre Martins Fernandes Diego de Souza Sardinha Instituto de Geociê ncias e ciê ncias exatas UNESP-Universidade Estadual Paulista S&#227 o Paulo Brasil centro de estudos Ambientais UNESP-Universidade Estadual Paulista S&#227 o Paulo Brasil UNIFAL-Universidade Federal de Alfenas Po&#231 os de Caldas Brasil

S?o Paulo State is the main sugar cane producer and these agricultural activities are carried out in predominantly sandy soils, which require large amounts of phosphate fertilizers and amendments. This work evaluated the fertilizer-effect on the Al, Ba, Fe, Mn and Ni released in a watershed with influence of sugar cane crops in the S?o Paulo State, Brazil, namely the Monjolo Grande Stream basin. Five surface water sampling campaigns were carried out at the mouth of Monjolo Grande Stream in February, April, June, September and November 2010, characterizing the following parameters: discharge, pH, temperature, electric conductivity, dissolved oxygen and total and dissolved concentrations of Al, Ba, Fe, Mn and Ni. Approximately 99% of Al and Fe are transported annually in association with suspended sediments carried to the Monjolo Grande Stream by sheet erosion. The results also demonstrated that the increasing Al, Ba, Fe and Mn concentrations dissolved in the waters of the Monjolo Grande Stream basin in the wet season are associated to phosphate fertilizers and amendments that are used extensively in agrichemical activities. However, with the current application rates, there has been no increase in the dissolved concentrations of these metals at levels that could pose risks to human health.

关键词： Sugar Cane Crops Phosphate Fertilizers and Amendments Total and Dissolved Metal environmental Management

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How does zebrafish support new strategies for neuroprotection and neuroregeneration in hypoxia-related diseases?

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Neural Regeneration Research 2016年第7期11卷 1069-1070页

作者： emerson S.Silva Joao Batista T.Rocha Diogo O.Souza Marcos M.Braga Programa de Pos-Graduacao em Bioquimica Departamento de Bioquimica Instituto de ciencias basicas da saude Universidade Federal do Rio Grande do Sul Porto Alegre RS Brazil Programa de Pos-Graduacao em Bioquimica Toxicologica Departamento de Bioquimica e Biologia Molecular Centro de ciencias Naturais e Exatas Universidade Federal de Santa Maria Santa MariaRS Brazil Instituto Nacional de ciencia e Tecnologia em excitotoxicidade e Neuroprotecao Universidade Federal do Rio Grande do Sul PortoAlegre RS Brazil

Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal *** subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen（O2）*** the brain p... 详细信息

关键词： How does zebrafish support new strategies for neuroprotection and neuroregeneration in hypoxia-related diseases

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Galvanic and asymmetry effects on the local electrochemical behavior of the 2098-T351 alloy welded by friction stir welding

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Journal of Materials Science & Technology 2020年第10期42卷 162-175页

作者： Mariana X.Milagre Uyime Donatus Naga V.Mogili Rejane Maria PSilva Barbara Victoria Gde Viveiros Victor F.Pereira Renato A.Antunes Caruline S.CMachado Joao Victor S.Araujo Isolda Costa Instituto de Pesquisas energeticas e Nucleares IPEN/CNENAv.Prof.Lineu Prestes2242Sao PauloBrazil Laboratorio Nacional de Nanotecnologia LNNano/CNPENRua Giuseppe Maximo Scolfaro10.000Polo II deAlta Tecnologia de CampinasBrazil centro de engenharia Modelagem e Ciencias Sociais AplicadasUFABCAv.dos Estados 5001Santo AndreBrazil

Scanning electrochemical microscopy(SeCM)and scanning vibrating electrode technique(SVeT)were used to investigate the electrochemical behaviour of the top surface of the 2098-T351 alloy welded by friction stir welding(FSW).The SVeT technique was efficient in identifying the cathodic and anodic weld *** welding joint(WJ),which comprises the thermomechanically affected zone(TMAZ)and the stir zone(SZ),was cathodic relative to the heated affected zone(HAZ)and the base metal(BM).The reactivities of the welding joint at the advancing side(AS)and the retreating side(RS)were analyzed and compared using SeCM technique in the competition mode by monitoring the dissolved oxygen as a redox mediator in 0.005 mol L^-1 NaCl *** RS was more electrochemically active than the AS,and these results were correlated with the microstructural features of the welded alloy.

关键词： Aluminum alloys Friction stir welding Localized corrosion

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Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute

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Regenerative Biomaterials 2021年第1期8卷 73-82页

作者： Isabel Pereira Jose eduardo Pereira Luis Maltez Alexandra Rodrigues Catarina Rodrigues Manuela Oliveira Dina MSilva Ana Rita Caseiro Justina Prada Ana Colette Mauricio Jose Domingos Santos Miguel Gama CeB Centre of Biological EngineeingUniversity of MinhoCampus de GualtarBraga 4710-057Portugal CeCAV Animal and Veterinary Research CentreUniversity of Trias-os-Montes e Alto DouroVila Real 5001-801Portugal department of Veterinary Sciences University of Tras-os-Montes e Alto DouroVila Real 5001-801Portugal Bios ckin Molecular and Cell Therapies S.A.Laboratorio CriovidaTecMaiaRua Engenheiro Frederico Ulrich 2650Moreira da Maia 4470-605Portugal departamento de Clinicas Veterinarias Instituto de Ciencias Biomedicas de Abel Salazar(ICBAS)Universidade do Porto(UP)Rua de Jorge Viterbo Ferreiran°228Porto 4050-313Portugal centro de estudos de ciencia Animal(CeCA) Instituto de CienciasTecnologias e Agroambiente da Universidade do Porto(ICETA)Rua D.Manuel IApartado 55142Porto 4051-401 Portugal centro de Investigaqao Vasco da Gama(ciVG)/escola Universitaria Vasco da Gama(eUVG) Avenida Jose R.Sousa Femandesn°197 LordemaoCoimbra 3020-210Portugal ReQUIMTe/LAQV Departamento de Engenharia Metalurgica e MateriaisFaculdade de EngenhariaUniversidade do PortoRua Dr Roberto FriasPorto 4200-495Portugal

The development of injectable bone substitutes(IBS)have obtained great importance in the bone re-generation field,as a strategy to reach hardly accessible defects using minimally invasive techniques and able to fit to irregular *** this scenario,the association of injectable hydrogels and bone graft granules is emerging as a well-established ***,in situ forming hydrogels have arisen as a new IBS *** in situ forming and injectable dextrin-based hydrogel(HG)was developed,aiming to act as a carrier of granular bone substitutes and bioactive *** this work,the HG was associated to a granular bone substitute(Bonelike)and implanted in goat critical-sized calvarial defects(14mm)for 3,6 and *** results showed that HG improved the han-dling properties of the Bonelike granules and did not affect its osteoconductive features,neither impairing the bone regener ation *** multipotent mesenchymal stromal cells from the umbilical cord,extracellular matrix hydrolysates and the pro-angiogenic peptide LLKKK18 were also combined with the *** bioactive agents did not enhance the new bone formation significantly under the conditions tested,according to micro-computed tomography and histological analysis.

关键词： polysaccharide injec table hydrogel granular ceramics Bonelike' bone regen eration calvarial defect

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Morphological and molecular diversity of arbuscular mycorrhizal fungi in revegetated iron-mining site has the same magnitude of adjacent pristine ecosystems

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Journal of environmental Sciences 2018年第5期30卷 330-343页

作者： Caroline Krug Vieira Matheus Nicoletti Marascalchi Arthur Vinicius Rodrigues Rafael Dutra de Armas Sidney Luiz Stürmer Universidade Regional de Blumenau(FURB) Programa de Pos-Graduacao em Engenharia Ambiental89030-903 BlumenauSCBrazil Universidade Regional de Blumenau(FURB) Departamento de Ciencias Naturais(DCN)89030-903 BlumenauSCBrazil Uniuersidade Regional de Blumenau(FURB) Programaa de Pos-Graduacao em Engenharia Florestal89030-903 BlumenauSCBrazil centro Universitario-Catolica de Santa Catarina 89203-005 JoinvilleSCBrazil

Arbuscular mycorrhizal fungi（AMF） are important during revegetation of mining sites, but few studies compared AMF community in revegetated sites with pristine adjacent ecosystems. The aim of this study was to assess AMF species richness in a revegetated iron-mining site and adjacent ecosystems and to relate AMF occurrence to soil chemical parameters. Soil samples were collected in dry and rainy seasons in a revegetated iron-mining site（RA） and compared with pristine ecosystems of forest（FL）, canga（NG）,and Cerrado（Ce）. AMF species were identified by spore morphology from field and trap cultures and by LSU r DNA sequencing using Illumina. A total of 62 AMF species were recovered, pertaining to 18 genera and nine families of Glomeromycota. The largest number of species and families were detected in RA, and Acaulospora mellea and Glomus sp1 were the most frequent species. Species belonging to Glomeraceae and Acaulosporaceae accounted for 42%–48% of total species richness. Total number of spores and mycorrhizal inoculum potential tended to be higher in the dry than in the rainy season, except in RA. Sequences of uncultured Glomerales were dominant in all sites and seasons and five species were detected exclusively by DNA-based identification. Redundancy analysis evidenced soil p H,organic matter, aluminum, and iron as main factors influencing AMF presence. In conclusion, revegetation of the iron-mining site seems to be effective in maintaining a diverse AMF community and different approaches are complementary to reveal AMF species, despite the larger number of species being identified by traditional identification of field spores.

关键词： Community structure Glomeromycota Illumina LSU rDNA Spore morphology Taxonomic distinctness index

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Influence of Testing Temperature on the Corrosion Behavior of API 5L X70 Pipeline Steel

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Journal of Mechanics engineering and Automation 2014年第6期4卷 528-532页

作者： Carlos Antonio Vieira de Almeida Machado Renato Altobelli Antunes elisabete Jorge Pessine Olandir Vercino Correa centro de engenharia Modelagem e Ci~ncias Sociais Aplicadas (CECS) Universidade Federal do ABC Santo Andre 09210-580Brazil centro de ciencia e Tecnologia de Materiais (CCTM) Instituto de Pesquisas Energeticas e Nucleares(IPEN/CNEN-SP) Cidade Universitaria Sao Paulo 05508-000 Brazil

It is known that localized corrosion attack takes a preponderant role in the onset of stress corrosion cracking of pipeline steels in high pH conditions. Carbonate/bicarbonate solutions can be employed to study the localized corrosion behavior of these materials. In addition to the presence of chloride ions in the electrolyte, the solution temperature is also of prime importance to the onset of pitting corrosion. The aim of this work is to evaluate the influence of the testing temperature on the corrosion behavior of the API 5L X70 pipeline steel which is a standard material for gas pipelines in Brazil. Samples were exposed to a solution consisting of Na2CO3, NaHCO3 and NaCl at three different temperatures： RT （room temperature）, 40 ℃ and 60 ℃. The corrosion morphology was observed using SeM （scanning electron microscopy）. The results showed that pitting corrosion became facilitated when the steel was immersed at higher temperatures.

关键词： API 50 X70 pipeline steel corrosion temperature

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effect of Adjunct Culture <i>Lactobacillus helveticus</i>(B02) on the Composition, Proteolysis, Free Amino Acids Release and Sensory Characteristics of Prato Cheese

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Food and Nutrition Sciences 2017年第5期8卷 512-525页

作者： Natália Chinellato de Azambuja Izildinha Moreno darlila Aparecida Gallina Leila Maria Spadoti eliana Maria Pettirossi Motta Maria Teresa Bertolodo Pacheco Angela Lima Menêses de Queiroz Adriane elisabete Costa Antunes Faculdade de ciências Aplicadas Universidade Estadual de Campinas (FCA/UNICAMP) Limeira Brazil centro de Tecnologia de Laticínios Instituto de Tecnologia de Alimentos (TECNOLAT/ITAL) Campinas Brazil Faculdade de engenharia de Alimentos Universidade Estadual de Campinas (FEA/UNICAMP) Campinas Brazil centro de ciência e Qualidade de Alimentos Instituto de Tecnologia de Alimentos (CCQA/ITAL) Campinas Brazil centro de Tecnologia Universidade Federal da Paraíba Jo&#227o Pessoa Brazil

At semi-industrial scale it was obtained two cheeses, one with aromatic culture (CHN) and the other with also L. helveticus (CHN + LH). Proteolysis during ripening was evaluated using proteolytic indices, electrophoretic profile Urea-PAGe and release of free amino acids. Sensory evaluation was performed by acceptability test. It was observed a 5-fold increase in the fraction corresponding to αs1-I-casein in the CHN cheese and 6.5 times in the CHN + LH cheese and 7.2 and 8.2 increase respectively, for total amino acids. Prato cheese with the adjunct culture showed higher acceptability in terms of overall aroma and flavor.

关键词： Amino Acids Cheese L. helveticus Ripening Sensory Analysis

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DC Plasma Technology Applied to Powder Metallurgy: an Overview

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Plasma Science and Technology 2013年第1期15卷 70-81页

作者： A. N. KLeIN R. P. CARDOSO H. C. PAVANATI C. BINdeR A. M. MALISKA G. HAMMeS D. FUSAO A. SeeBeR S. F. BRUNATTO J. L. R. MUZART LabMat (Materials Laboratory) Departamento de Engenharia Mec~nica Universidade Federal de Santa Catarina (UFSC) 88040-900 FlorianSpolis - SC Brazil departamento de engenharia Mecanica Universidade Federal do Parana (UFPR) 81531-990 Curitiba- PR Brazil departamento Academico de Metal-Mecanica Instituto Federal de Santa Catarina (IFSC) 88020-300 Florianopolis - SC Brazil Universidade Tecnologica Federal do Parana (UTFPR) 84016-210 Ponta Grossa - PR Brazil centro de ciencia e Tecnologia Universidade de Caxias do Sul 95070-560 Caxias do Sul- RS Brazil

DC plasma is a very promising technology for processing different materials, and is becoming especially interesting when low environmental impact and high-performance treatments are needed. Some of the intrinsic characteristics of DC plasma technology, which make it suitable for powder metallurgy （PM） and powder injection molding （PIM） parts production, are low- pressure processing and plasma environment high reactivity. Moreover it can be considered as a highly competitive green technology. In this work, an overview of some of the important DC plasma techniques applied to PM and PIM parts processing is presented. emphasis is given to the descriptions of the main characteristics and the technique potentials of plasma-assisted nitriding, plasma-assisted thermal debinding, plasma-assisted sintering, and simultaneously plasma-assisted sintering and surface alloying. The aspects presented and discussed in this paper indicate that DC plasma processes are promising and competitive techniques for PM and PIM parts processing.

关键词： powder metallurgy DC glow discharge plasma nitriding plasma sintering,plasma-assisted thermal debinding surface alloying

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