检索结果-南通市图书馆

Multi‑omics integration identifies regulatory factors underlying bovine subclinical mastitis

Journal of Animal Science and Biotechnology 2024年第3期15卷 987-1007页

作者： Mengqi Wang Naisu Yang Mario Laterriere David Gagne Faith Omonijo Eveline M.Ibeagha‑Awemu Agriculture and Agri‑Food Canada Sherbrooke Research and Development CentreSherbrookeQCCanada Department of Animal Science Universite LavalQuebec CityQCCanada Quebec Research and development centre Agriculture and Agri-Food CanadaQuebec CityQCCanada

Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy ***-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease ***,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus *** Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical *** abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),***,5 factors presenting the principal variation of differential multi-omics signatures were *** important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were *** of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical ***,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regu

关键词： Candidate discriminant multi-omics signature Gene Long non-coding RNA Methylation haplotype block MicroRNA Multi-omics integration Natural killer cell mediated cytotoxicity pathway Staphylococcus aureus infection pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A new Late Miocene Hystrix(Hystricidae,Rodentia)from Turkey

引用

Integrative Zoology 2024年第3期19卷 548-563页

作者： Kazım HALAÇLAR Ayla SEVIM EROL Tolga KÖROG˘LU Paul RUMMY Tao DENG Serdar MAYDA Natural History Application and Research centre Ege UniversityTurkey Key Laboratory of Vertebrate Evolution and human Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijingPeople’s Republic of China Department of Anthropology Faculty of Languages and HistoryGeographyAnkara UniversityTurkey Department of Biology Faculty of SciencesEge UniversityTurkey

TheÇorakyerler fossil locality in Anatolia reveals unique faunal *** study introduces Hystrix kayae ***.,a new Late Miocene porcupine initially classified as Hystrix *** et al.,*** finding expands our knowledge of Late Miocene Anatolian porcupines,bringing the total number of known species to *** *** larger than Hystrix aryanensis and exhibits greater upper cheek tooth crown *** cheek tooth morphology differs from Hystrix depereti,and it possesses distinctive U-shaped choanae unlike Hystrix ***Çorakyerler locality may predate sites with *** and *** but aligns temporally with Hystrix parvae *** study enhances our understanding of Late Miocene porcupine diversity in Anatolia,emphasizing the importance ofÇorakyerler in unraveling the evolutionary history of these fascinating mammals.

关键词： Çorakyerler Hystrix Late Miocene paleobiogeography Turkey

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comprehending drivers of land use land cover change from 1999 to 2021 in the Pithoragarh District,Kumaon Himalaya,Uttarakhand,India

引用

Journal of Mountain Science 2024年第7期21卷 2394-2407页

作者： Mahika PHARTIYAL Sanjeev SHARMA centre for the Study of Regional development Jawaharlal Nehru UniversityNew Delhi 110067India

The Himalayan region has been experiencing stark impacts of climate change,demographic and livelihood pattern *** analysis of land use and land cover(LULC)change provides insights into the shifts in spatial and temporal patterns of *** changes are the combined effects of anthropogenic and natural/climatic *** present study attempts to monitor and comprehend the main drivers behind LULC changes(1999-2021)in the Himalayan region of Pithoragarh district,*** district is a border district,remotely located in the north-east region of Uttarakhand,*** study draws upon primary and secondary data sources.A total of 400 household surveys and five group discussions from 38 villages were conducted randomly to understand the climate perception of the local community and the drivers of *** imagery,CRU(Climatic Research Unit)climate data and climate perception data from the field have been used to comprehensively comprehend,analyze,and discuss the trends and reasons for LULC *** and remote sensing techniques were used to construct LULC *** multifaceted approach ensures comprehensive and corroborated *** classes were identified and formed viz-cultivation,barren,settlement,snow,and *** show that vegetation and builtup have increased whereas cultivation,barren land,and snow cover have *** study further aims to elucidate the causes behind LULC changes in the spatially heterogeneous region,distinguishing between those attributed to human activities,climate shifts,and the interconnected impacts of *** study provides a comprehensive picture of the study area and delivers a targeted understanding of local drivers and their potential remedies by offering a foundation for formulating sustainable adaptation policies in the region.

关键词： Himalayan region Land use/land cover change Anthropogenic factors Climate change Socioecological system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study of plasma parameters of coaxial plasma source using triple Langmuir probe and Faraday cup diagnostics

引用

Plasma Science and Technology 2024年第4期26卷 94-100页

作者： Sunil KANCHI Rohit SHUKLA Archana SHARMA Pulsed Power and Electromagnetics Division Bhabha Atomic Research CentreVisakhapatnam 531011India Homi Bhabha National Institute Mumbai 400085India Beam Technology development Group Bhabha Atomic Research CentreMumbai 400085India

Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon *** triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.

关键词： coaxial plasma source triple Langmuir probe Faraday cup plasma density plasma temperature

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Design of an automated robotic microinjection system for batch injection of zebrafish embryos and larvae

引用

Microsystems & Nanoengineering 2024年第1期10卷 89-103页

作者： Zhongyi Guo Nana Ai Wei Ge Qingsong Xu Department of Electromechanical Engineering Faculty of Science and TechnologyUniversity of MacaoMacaoChina Department of Biomedical Sciences and centre of Reproduction Development and Aging(CRDA)Faculty of Health SciencesUniversity of MacaoMacaoChina

This paper presents the design of a vision-based automated robotic microinjection system for batch injection of both zebrafish embryos and larvae.A novel visual recognition algorithm based on an automatic threshold and excessive dilatation is introduced to accurately identify the center of zebrafish embryos and larval yolks.A corresponding software system is developed using the producer-consumer model as the framework structure,and a friendly user interface is designed to allow operators to choose from a range of desired functions according to their different *** addition,a novel microstructural agarose device is designed and fabricated to simultaneously immobilize mixed batches of embryos and ***,a prototype microinjection system is fabricated by integrating hardware devices with visual *** experimental study is conducted to verify the performance of the robotic microinjection *** results show that the reported system can accurately identify zebrafish embryos and larvae and efficiently complete batch microinjection tasks of the mixtures with an injection success rate of 92.05%in 13.88 s per *** with manual and existing microinjection systems,the proposed system demonstrates the merits of versatility,excellent efficiency,high success rate,high survival rate,and sufficient stability.

关键词： zebra automated hardware

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tropical Cyclone Monitoring and Analysis Techniques: A Review

引用

Journal of Meteorological Research 2024年第2期38卷 351-367页

作者： Chuanhai QIAN Ying LI Yinglong XU Xin WANG Zenghai ZHANG Gaozhen NIE Da LIU Shiwen ZHANG Institute for development and Programme Design China Meteorological AdministrationBeijing 100081 Chinese Academy of Meteorological Sciences China Meteorological AdministrationBeijing 100081 National Meteorological centre China Meteorological AdministrationBeijing 100081 National Satellite Meteorological centre China Meteorological AdministrationBeijing 100081

Tropical cyclones(TCs),including tropical depressions and different categories of typhoons,hurricanes,and cyclonic storms,mostly originate over the oceans in the absence of direct ***,detailed monitoring and analysis of TCs has always been an unsolved *** the recent 20 years,great changes have taken place in domestic and foreign TC monitoring techniques,imposing a significant impact on TC operations and *** new technologies and products gradually emerge to support operations,with improved monitoring *** this paper,the progress on TC monitoring and analysis via meteorological satellites,radars,and airplanes in China and the world is reviewed,compared,and summarized,with special focuses on multisatellite fusion observations,in situ aircraft measurements,and some unconventional observation equipment such as rockets,saildrones,and underwater *** this basis,the paper points out future directions for improving TC monitoring and analysis in aid of better TC forecast and early warning.

关键词： tropical cyclone(TC) monitoring and analysis meteorological satellite aircraft reconnaissance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Method for Detecting and Recognizing Yi Character Based on Deep Learning

引用

Computers, Materials & Continua 2024年第2期78卷 2721-2739页

作者： Haipeng Sun Xueyan Ding Jian Sun HuaYu Jianxin Zhang School of Computer Science and Engineering Dalian Minzu UniversityDalian116600China Institute of Machine Intelligence and Bio-Computing Dalian Minzu UniversityDalian116600China 3Yi Language Research RoomChina Ethnic languages Translation centre Beijing100080China

Aiming at the challenges associated with the absence of a labeled dataset for Yi characters and the complexity of Yi character detection and recognition,we present a deep learning-based approach for Yi character detection and *** the detection stage,an improved Differentiable Binarization Network(DBNet)framework is introduced to detect Yi characters,in which the Omni-dimensional Dynamic Convolution(ODConv)is combined with the ResNet-18 feature extraction module to obtain multi-dimensional complementary features,thereby improving the accuracy of Yi character ***,the feature pyramid network fusion module is used to further extract Yi character image features,improving target recognition at different ***,the previously generated feature map is passed through a head network to produce two maps:a probability map and an adaptive threshold map of the same size as the original *** maps are then subjected to a differentiable binarization process,resulting in an approximate binarization *** map helps to identify the boundaries of the text ***,the text detection box is generated after the post-processing *** the recognition stage,an improved lightweight MobileNetV3 framework is used to recognize the detect character regions,where the original Squeeze-and-Excitation(SE)block is replaced by the efficient Shuffle Attention(SA)that integrates spatial and channel attention,improving the accuracy of Yi characters ***,the use of depth separable convolution and reversible residual structure can reduce the number of parameters and computation of the model,so that the model can better understand the contextual information and improve the accuracy of text *** experimental results illustrate that the proposed method achieves good results in detecting and recognizing Yi characters,with detection and recognition accuracy rates of 97.5%and 96.8%,*** also,we have compared the detection and re

关键词： Yi characters text detection text recognition attention mechanism deep neural network

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Revealing Voyage Visit to China dispels misperceptions,shows the real picture of China-Africa friendship

引用

ChinAfrica 2024年第9期16卷 62-63页

作者： GEORGE MUSIIME development Watch centre Nigeria

It is very easy for an African living in Africa to be misled into believing that the China-Africa friendship is *** fact,with so much of information reaching Africa about China-Africa cooperation being targeted at undermining the friendly relations enjoyed by the two sides and the e!orts to build a China-Africa community with a shared future,this in a way is not surprising.

关键词： Africa superficial friends

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insights for Africa’s Industrialisation

引用

ChinAfrica 2024年第1期16卷 14-15页

作者： ZHANG JIN CHEN XIAO centre for International Knowledge on development Beijing

The First Industrial Revolution in the 18th century started the modernisation process marked by profound economic,social,and cultural transformations in the *** shows that the process of industrialisation is closely associated with improvements in people’s living standards and their quality of ***,with economic and technological change at its core,is central to modernisation.

关键词： Africa profound economic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Studies on the temporal,structural,and interacting features of the clubroot resistance gene Rcr1 using CRISPR/Cas9-based systems

引用

Horticultural Plant Journal 2024年第4期10卷 1035-1048页

作者： Hao Hu Fengqun Yu Agriculture and Agri-Food Canada Saskatoon Research and Development Centre107 Science PlaceSaskatoonSKS7N OX2Canada

Clubroot disease is a severe threat to Brassica crops globally,particularly in western *** resistance,achieved through pyramiding clubroot resistance(CR)genes with different modes of action,is the most important strategy for managing the ***,studies on the CR gene functions are quite *** this study,we have conducted investigations into the temporal,structural,and interacting features of a newly cloned CR gene,Rcr1,using CRISPR/Cas9 *** temporal functionality,we developed a novel CRISPR/Cas9-based binary vector,pHHIGR-Hsp18.2,to deliver Rcr1 into a susceptible canola line(DH12075)and observed that early expression of Rcr1 is critical for conferring *** structural functionality,several independent mutations in specific domains of Rcr1 resulted in loss-offunction,highlighting their importance for CR *** the study of the interacting features of Rcr1,a cysteine protease gene and its homologous allele in canola were successfully disrupted via CRISPR/Cas9 as an interacting component with Rcr1 protein,resulting in the conversion from clubroot resistant to susceptible in plants carrying intact *** results indicated an indispensable role of these two cysteine proteases in Rcr1-mediated resistance *** study,the first of its kind,provides valuable insights into the functionality of ***,the new vector p HHIGR-Hsp18.2 demonstrated an inducible feature on the removal of add-on traits,which should be useful for functional genomics and other similar research in brassica crops.

关键词： Clubroot resistance Brassica crops Canola Rcr1 CRISPR/Cas9 system Gene knock-out Timing control Non-synonymous mutation Protein-protein interaction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：