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Parametric analysis of craniocerebral injury mechanism in pedestrian trafficaccidents based on finite element methods

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Chinese Journal of Traumatology 2024年第4期27卷 187-199页

作者： Jin-Ming Wang Zheng-Dong Li Chang-Sheng Cai Ying Fan Xin-Biao Liao Fu Zhang Jian-Hua Zhang Dong-Hua Zou Academy of forensic science Shanghai Key Laboratory of Forensic MedicineKey Laboratory of Forensic ScienceMinistry of JusticeShanghai Forensic Service PlatformShanghai200063China School of forensic Medicine Guizhou Medical UniversityGuiyang550004China Key laboratory of forensic Pathology Ministry of Public Security PR ChinaGuangzhou510050China

Purpose:The toughest challenge in pedestrian traffic accident identification lies in ascertaining *** study aimed to systematically simulate and parameterize 3 types of craniocerebral injuryincluding impact injury,fall injury,and run-over injury,to compare the injury response outcomes ofdifferent injury ***:Based on the total human model for safety(THUMS)and its enhanced human model THUMShollow structures,a total of 84 simulations with 3 injury manners,different loading directions,andloading velocities were *** Mises stress,intracranial pressure,maximum principal strain,cumulative strain damage measure,shear stress,and cranial strain were employed to analyze the injuryresponse of all areas of the *** examine the association between injury conditions and injuryconsequences,correlation analysis,principal component analysis,linear regression,and stepwise linearregression were ***:There is a significant correlation observed between each criterion of skull and brain injury(p40 km/h),the Von Mises stress on the skull waswith a high possibility exceed the threshold for skull fracture(100 MPa).When falling and makingtemporal and occipital contact with the ground,the opposite side of the impacted area experienceshigher frequency stress concentration than contact at other ***-over injuries tend to have amore comprehensive craniocerebral injury,with greater overall deformation due to more adequate kinetic energy *** mean value of maximum principal strain of brain and Von Mises stress ofcranium at run-over condition are 1.39 and 403.8 MPa,while they were 1.31,94.11 MPa and 0.64,120.5 MPa for the impact and fall conditions,*** impact velocity also plays a significant rolein craniocerebral injury in impact and fall loading conditions(the p

关键词： Craniocerebral injury Finite element Injury mechanism Traffic accident Biomechanism forensic practice

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Integrating machine learning and CALPHAD method for exploring low-modulus near-β-Ti alloys

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Rare Metals 2024年第1期43卷 309-323页

作者： Hao Zou Yue-Yan Tian Li-Gang Zhang Ren-Hao Xue Zi-Xuan Deng Ming-Ming Lu Jian-Xin Wang Li-Bin Liu School of Computer science and Engineering Central South UniversityChangsha 410083China School of Materials science and Engineering Central South UniversityChangsha 410083China State Key laboratory of Powder Metallurgy Central South UniversityChangsha 410083China

Traditional theoretical and empirical calculation methods can guide the design of β-and metastable β-alloys for bio-titanium. However, it is still difficult to obtain novel near-β-Ti alloys with low modulus. This study developed a method that combines machine learning with calculation of phase diagrams(CALPHAD) to facilitate the design of near-β-Ti alloys. An elastic modulus database of Ti–Nb–Zr–Mo–Ta–Sn system was constructed first, and then three features(the electron to atom ratio, mean absolute deviation of atom mass, and mean electronegativity) were selected as the key factors of modulus by performing a three-step feature selection. With these features, a highly accurate model was built for predicting the modulus of near-β-Ti alloys. To further ensure the accuracy of modulus prediction, machine learning with the elastic constants calculated was leveraged by CALPHAD database. The root mean square error of the well-trained model can be as low as 6.75 GPa. Guided by the prediction of machine learning and CALPHAD, three novel near-β-Ti alloys with elastic modulus below 50 GPa were successfully designed in this study. The best candidate alloy(Ti–26Nb–4Zr–4Sn–1Mo–Ta) exhibits an ultra-low modulus(36.6 GPa) after cold rolling with a thickness reduction of 20%. Our method can greatly save time and resources in the development of novel Ti alloys, and experimental verifications have demonstrated the reliability of this method.

关键词： Near-β-Ti alloy Machine learning Calculation of phase diagram Low-modulus alloy Feature selection

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Developing Core-Shell Nano-Structures in FeCrAl-ODS Ferritic Alloys with the Co-Addition of Ni and Zr

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 364-372页

作者： Wenquan Ding Jieli Ma Yong Jiang Yiren Wang Huiqun Liu Key laboratory for Nonferrous Materials of Ministry of Education School of Materials Science and EngineeringCentral South UniversityChangsha410083China National Key laboratory for Powder Metallurgy Central South UniversityChangsha410083China

A new Ni+Zr co-alloyed FeCrAl-ODS(oxide-dispersion-strengthened)ferritic alloy was fabricated by ball-milling and *** electron microscopy and atom probe tomography,the dispersive formation of high density core-shelled nano-particles of various sizes was confirmed with a common B2-NiAl *** which,median-sized nano-particles(20-50 nm)typically have an Y_(4)Al_(2)O_(9)nano-core of<~20 nm,ultra-fine nano-particles(<~20)nm have an Y_(4)Zr_(3)O_(12)nano-core of<~10 nm,and larger-sized nano-particles(50-100 nm)incorporate an ultra-fine Y_(4)Al_(2)O_(9)nano-core and a few ultra-fine Y_(4)Zr_(3)O_(12)*** these nano-phases were highly coherent with the ferritic *** large Y--Al-O nano-oxides were *** total number density of ultra-fine nano-particles was estimated as~2×10^(23)m^(-3)with a mean size of 6.3 nm only,and accordingly,the new alloy achieved an excellent combination of strength and ductility at high temperatures.

关键词： FeCrAl Oxide-dispersion-strengthened(ODS)alloy Mechanical alloying Nano-oxides Core-shell

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Effect of forging on the microstructure and texture of a high Nb containing γ-TiAl alloy

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Journal of central South University 2024年第6期31卷 1763-1773页

作者： TAO Hui LI Hui-zhong WANG Li ZHOU Rui CHE Yi-xuan CHEN Yong-hui LIANG Xiao-peng School of Materials science and Engineering Central South UniversityChangsha 410083China State Key laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Key laboratory of Nonferrous Metal Materials science and Engineering Central South UniversityChangsha 410083China Department of Materials science and Engineering City University of Hong KongKowloon 999077Hong KongChina

The effect of forging on the microstructure and texture evolution of a high Nb containing Ti-45Al-7Nb-0.3W(at.%)alloy was investigated by X-ray diffractometer(XRD),scanning electron microscopy(SEM),and transmission electron microscopy(TEM).The results show that the as-cast alloy is mainly composed of α_(2)/γ lamellar colonies with a mean size of 70μm,but the hot-forged pancake displays a near duplex microstructure(DP).Kinking and bending of lamellar colonies,deformation twinning and dynamic recrystallization(DRX)occur during hot ***,dense dislocations in theβphase after forging suggest that the high-temperature β phase with a disordered structure is favorable for improving the hot-workability of the *** the common TiAl casting texture,the solidification process of the investigated as-cast alloy with high Nb content is completely via the β phase region,resulting in the formation of aγ fiber texture where theγ aligns parallel to the heat-flow *** comparison,the relatively strongand weaktexture components in the as-forged alloy are attributed to the deformation *** annealing,static recrystallization occurs at the twin boundary and intersections,which weakens the deformation texture.

关键词： high Nb containing γ-TiAl alloy forging microstructure texture β phase

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Impact of cooling rate on exfoliation corrosion resistance of a Li-containing 7xxx aluminum alloy

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Journal of central South University 2024年第7期31卷 2225-2236页

作者： JIANG Ke-da LIAO Ze-xin CHEN Ming-yang LIU Sheng-dan TANG Jian-guo School of Materials science and Engineering Central South UniversityChangsha 410083China National Key laboratory of science and Technology on High-strength Structural Materials Central South UniversityChangsha 410083China Key laboratory of Non-ferrous Metals Materials science and Engineering Ministry of EducationCentral South UniversityChangsha 410083China

The impact of cooling rate after solution heat treatment on exfoliation corrosion resistance of a Li-containing 7xxx aluminum alloy was investigated by accelerated immersion and electrochemical impedance spectroscopy test,optical microscope,electron backscatter diffraction and scanning transmission electron *** the decrease of cooling rate from 1700℃/s to 4℃/s,exfoliation corrosion resistance of the aged specimens decreases with rating changing from EA to EC and the maximum corrosion depth increasing from about 169.4μm to 632.1μ*** corrosion tends to develop along grain boundaries in the specimens with cooling rates higher than about 31℃/s and along both grain boundaries and sub-grain boundaries in the specimens with lower cooling *** reason has been discussed based on the changes of the microstructure and microchemistry at grain boundaries and sub-grain boundaries due to slow cooling.

关键词： 7xxx aluminum alloy cooling rate exfoliation corrosion microstructure

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Highly sensitive nanozyme strip:An effective tool for forensic material evidence identification

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Nano Research 2024年第3期17卷 1785-1791页

作者： Juanji Hong Zhanjun Guo Dihan Duan Yi Zhang Xin Chen Yongjiu Li Zheng Tu Lei Feng Lei Chen Xiyun Yan Lizeng Gao Minmin Liang Demin Duan Experimental Center of Advanced Materials School of Materials Science&EngineeringBeijing Institute of TechnologyBeijing 100081China College of Bioscience and Biotechnology Shenyang Agricultural UniversityShenyang 110866China Chongqing kangjuquanhong biology science and technology Co. ltdChongqing 400026China Key laboratory of forensic Genetics Institute of Forensic ScienceMinistry of Public SecurityBeijing 100038China CAS Engineering laboratory for Nanozyme Key Laboratory of BiomacromoleculesInstitute of BiophysicsChinese Academic of ScienceBeijing 100101China

During criminal case investigations,blood evidence tracing is critical for criminal ***,the blood stains are often cleaned or covered up after the crime,resulting in trace residue and difficult ***,a highly sensitive and specific method for the rapid detection of human blood stains remains *** solve this problem,we established a nanozyme-based strip for rapid detection of blood evidence with high sensitivity and *** construct reliable nanozyme strips,we synthesized CoFe_(2)O_(4) nanozymes with high peroxidase-like activity by scaling up to gram level,which can be supplied for six million tests,and conjugated antibody as a detection probe in nanozyme *** developed CoFe_(2)O_(4) nanozyme strip can detect human hemoglobin(HGB)at a concentration as low as 1 ng/mL,which is 100 times lower than the commercially available colloidal gold strips(100 ng/mL).Moreover,this CoFe_(2)O_(4) nanozyme strip showed high generality on 12 substrates and high specificity to human HGB among 13 animal blood ***,we applied the developed CoFe_(2)O_(4) nanozyme strip to successfully detect blood stains in three real cases,where the current commercial colloidal gold strip failed to *** results suggest that the CoFe_(2)O_(4) nanozyme strip can be used as an effective on-scene detection method for human blood stains,and can further be used as a long-term preserved material evidence for traceability inquiry.

关键词： CoFe_(2)O_(4)nanozyme nanozyme strip peroxidase-like activity human hemoglobin blood evidence

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Controlling the Si/C ratio in SiC matrix based on the modified polymethysilane for C/C-SiC composites with enhanced mechanical properties

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Journal of Advanced Ceramics 2024年第2期13卷 220-236页

作者： Mingdong Liao Xiebo Hu Chenghao Zhong Ping Xu Xiaodong Wang Ze Zhang Peng Zhou Mingyu Zhang Zhean Su Qizhong Huang National Key laboratory of science and Technology on High-Strength Structural Materials Central South UniversityChangsha 410083China

Fabricating SiC matrix with controllable Si/C ratio for C/C-SiC composites via precursor infiltration and pyrolysis is difficult to realize due to the absence of suitable ***,SiC precursors with Si-rich(Si/C=1.23),nearstoichiometric(Si/C=1.01),and C-rich(Si/C=0.88)pyrolyzed ceramics at 1200℃ were successfully synthesized by the novel modification of *** structure and ceramization of synthesized SiC precursors were studied,and C/C-SiC composites with similar Si/C ratio in SiC matrix were also *** results revealed that the defects and Young’s modulus of SiC matrix and the thermal residual stress on pyrolytic carbon coated carbon fiber were determined by the Si/C *** a result,the Si/C ratio exerted significant effects on the crack deflection behavior and the mechanical properties of the *** composites with near-stoichiometric SiC matrix showed excellent mechanical properties because of the effective crack deflection and the moderate Young’s modulus of their SiC *** flexural strength,flexural modulus,and compressive strength were 423±27 MPa,33.41±4.52 GPa,and 393±8 MPa,***,after a heat treatment at 1600℃,the role of carbon fiber toughening was improved and accompanied by a decrease in mechanical properties for all composites,which was attributed to the increased defects in SiC matrix and the damaged interfaces by the thermal residual stress.

关键词： SiC precursor Si/C ratio polymethysilane C/C–SiC composites mechanical properties

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Structural and magnetic properties of micropolycrystalline cobalt thin films fabricated by direct current magnetron sputtering

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International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 384-394页

作者： Kerui Song Zhou Li Mei Fang Zhu Xiao Qian Lei School of Materials science and Engineering Central South UniversityChangsha 410083China State Key laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Hunan Key laboratory of Super-Microstructure and Ultrafast Process School of Physics and electronicsCentral South UniversityChangsha 410083China Key laboratory of Non-Ferrous Metal Materials science and Engineering Ministry of EducationChangsha 410083China

Pure cobalt(Co)thin films were fabricated by direct current magnetron sputtering,and the effects of sputtering power and pres-sure on the microstructure and electromagnetic properties of the films were *** the sputtering power increases from 15 to 60 W,the Co thin films transition from an amorphous to a polycrystalline state,accompanied by an increase in the intercrystal pore ***,the resistivity decreases from 276 to 99μΩ·cm,coercivity increases from 162 to 293 Oe,and in-plane magnetic aniso-tropy *** the sputtering pressure decreases from 1.6 to 0.2 Pa,grain size significantly increases,resistivity significantly de-creases,and the coercivity significantly increases(from 67 to 280 Oe),which can be attributed to the increase in defect ***-pondingly,a quantitative model for the coercivity of Co thin films was *** polycrystalline films sputtered under pressures of 0.2 and 0.4 Pa exhibit significant in-plane magnetic anisotropy,which is primarily attributable to increased microstress.

关键词： cobalt thin film magnetron sputtering microstructure electromagnetic properties

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Mitophagy in intracerebral hemorrhage:a new target for therapeutic intervention

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Neural Regeneration Research 2024年第2期19卷 316-323页

作者： Yiyang Chen Wenxuan Tang Xinqi Huang Yumei An Jiawen Li Shengye Yuan Haiyan Shan Mingyang Zhang Institute of forensic sciences Suzhou Medical CollegeSoochow UniversitySuzhouJiangsu ProvinceChina Shanghai Key Lab of forensic Medicine Key Lab of Forensic ScienceMinistry of Justice(Academy of Forensic Science)ShanghaiChina Department of Obstetrics and Gynecology The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhouJiangsu ProvinceChina

Intracerebral hemorrhage is a life-threatening condition with a high fatality rate and severe ***,there is currently no treatment available for intracerebral hemorrhage,unlike for other stroke *** studies have indicated that mitochondrial dysfunction and mitophagy likely relate to the pathophysiology of intracerebral ***,or selective autophagy of mitochondria,is an essential pathway to preserve mitochondrial homeostasis by clearing up damaged *** markedly contributes to the reduction of secondary brain injury caused by mitochondrial dysfunction after intracerebral *** review provides an overview of the mitochondrial dysfunction that occurs after intracerebral hemorrhage and the underlying mechanisms regarding how mitophagy regulates it,and discusses the new direction of therapeutic strategies targeting mitophagy for intracerebral hemorrhage,aiming to determine the close connection between mitophagy and intracerebral hemorrhage and identify new therapies to modulate mitophagy after intracerebral *** conclusion,although only a small number of drugs modulating mitophagy in intracerebral hemorrhage have been found thus far,most of which are in the preclinical stage and require further investigation,mitophagy is still a very valid and promising therapeutic target for intracerebral hemorrhage in the long run.

关键词： intracerebral hemorrhage mitochondrial dysfunction mitophagy neuroinflammation neuroprotection reactive oxygen species secondary brain injury therapeutic target

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On the low cycle fatigue behaviour of an Al-Zn-Mg-Cu alloy processed via non-isothermal ageing

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Journal of Materials science & Technology 2024年第1期168卷 227-238页

作者： Guangyi Guo Guofu Xu Yuan Tang Zhihao Zhao Zhihao Yi Haoran Li Ruohan Wang Xiaoyan Peng School of Materials science and Engineering Central South UniversityChangsha 410083China Key laboratory of Nonferrous Materials science and Engineering of Ministry of Education Changsha 410083China

The low cycle fatigue behaviour of an Al-Zn-Mg-Cu alloy processed via non-isothermal ageing(NIA)was examined at different strain *** showed that NIA improved the low cycle fatigue life(more than 7000 cycles)by optimising the precipitate configuration within 5.5 h while maintaining comparable mechanical properties(570 MPa for tensile strength)and conductivity(nearly 39%IACS)to conventional isothermal ageing,*** observation combined with molecular dynamic simula-tion revealed that precipitation configuration manipulated by NIA had a crucial effect on fatigue resis-tance.A great number of repeatedly sheared and locally destructed GP zones enhanced co-planar slip and slip localisation in the under-aged alloy during the early stage of NIA,responsible for the dramatic displacement steps on the surface and resultant poor fatigue *** the NIA further proceeded,moderately coarsened precipitates with an average dimension of 6.0 nm and elevated number density ef-fectively impeded the dislocation movement and weaken the slip localisation to a great extent,improving the fatigue performance within a few hours.

关键词： Non-isothermal ageing Fatigue Al-Zn-Mg-Cu alloy Precipitate manipulation Slip localization

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