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Floral biology and pollination mechanisms of four Mexico-endemic Fuchsia species with contrasting reproductive systems

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Journal of Plant Ecology 2018年第1期11卷 123-135页

作者： Clementina González Anai Alvarez-Baños Eduardo Cuevas CONACYT-Instituto de Investigaciones sobre los Recursos Naturales Universidad Michoacana de San Nicolás de HidalgoAv.San Juanito Itzícuaro s/nCol.Nueva EsperanzaMorelia Michoacán 58330México Facultad de Biología Universidad Michoacana de San Nicolás de HidalgoAv.Francisco J.Mújica S/NCiudad UniversitariaMoreliaMichoacán 58030México departamento de Biología Vegetal y Ecología Universidad de SevillaApartado 109541080 SevillaSpain

Aims The evolution of the outstanding variation of reproductive systems in angiosperms has been considered an important driver of line-age *** related hermaphroditic and dioecious species with biotic pollination provide the opportunity to study and compare traits related to pollinator attraction and their con-sequences on reproductive components.A higher predictability of pollination syndromes is expected in dioecious species,which are dependent on pollinators,than in self-compatible hermaphroditic *** species may suffer pollen limitation depending on the quality of floral rewards and the kind and abundance of pollina-tors,whereas no pollen limitation is expected in hermaphroditic spe-cies with autonomous ***,in the absence of pollen limitation,more or better seeds are expected in dioecious species,according to the sexual specialization *** In natural populations of the hermaphroditic Fuchsia fulgens and Fuchsia arborescens and dioecious Fuchsia parviflora and Fuchsia obconica,all endemic to Mexico,we first described flower phenol-ogy,flower production and longevity and nectar volume and ***,we evaluated the correspondence between floral visitors and pollination *** hermaphrodite plants,we determined the level of herkogamy and the potential for autonomous ***,we evaluated the effect of pollen limitation on fruit set and seed number and assessed seed germination for all *** Findings In contrast to our prediction,dioecious species did not show a higher correspondence between pollination syndromes and floral visitors than did hermaphrodites;however,male flowers exhib-ited a higher correspondence than female *** pollen limitation was detected in dioecious species,for which visitation rate did not differ between male and female *** her-maphroditic *** showed pollen limitation for seed number,despite the presence of auto

关键词： dioecy herkogamy hermaphroditism pollen limitation pollination syndromes

Rethinking de novo immune hepatitis,an old concept for liver allograft rejection:relevance of glutathione S-transferase T1 mismatch

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World Journal of Gastroenterology 2018年第29期24卷 3239-3249页

作者： Isabel Aguilera Elena Aguado-Dominguez Jose Manuel Sousa Antonio Nunez-Roldan department of Immunology Instituto de Biomedicina de Sevilla(IBIS)Hospital Universitario Virgen del RocíoSevilla 41013Spain Digestive and Liver Diseases Service Hospital Universitario Virgen del RocíoSevilla 41013Spain

Antibody-mediated rejection(AMR) in liver transplantation has long been underestimated. The concept of the liver as an organ susceptible to AMR has emerged in recent years, not only in the context of the major histocompatibility complex with the presence of HLA donor-specific antibodies, but also with antigens regarded as "minor", whose role in AMR has been demonstrated. Among them, antibodies against glutathione S-transferase T1 have been found in 100% of patients with de novo autoimmune hepatitis(dn AIH) when studied. In its latest update, the Banff Working Group for liver allograft pathology proposed replacing the term dn AIH with plasma cell(PC)-rich rejection. Antibodies to glutathione S-transferase T1(GSTT1) in null recipients of GSTT1 positive donors have been included as a contributory but nonessential feature of the diagnosis of PC-rich rejection. Also in this update, non-organ-specific anti-nuclear or smooth muscle autoantibodies are no longer included as diagnostic criteria. Although initially found in a proportion of patients with PC-rich rejection, the presence of autoantibodies is misleading since they are not diseasespecific and appear in many different contexts as bystanders. The cellular types and proportions of the inflammatory infiltrates in diagnostic biopsies have been studied in detail very recently. PC-rich rejection biopsies present a characteristic cellular profile with a predominance of T lymphocytes and a high proportion of PCs, close to 30%, of which 16.48% are Ig G4+. New data on the relevance of GSTT1-specific T lymphocytes to PC-rich rejection will be discussed in this review.

关键词： glutathione S-transferase T1 mismatch liver allograft rejection plasma cell-rich rejection de novo autoimmune hepatitis donor-specific antibodies newCAST cell quantification IgG4+plasma cell T lymphocytes

The importance of functional diversity in the stability of Mediterranean shrubland communities after the impact of extreme climatic events

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Journal of Plant Ecology 2017年第2期10卷 281-293页

作者： Enrique Gde la Riva Francisco Lloret Ignacio MPérez-Ramos Teodoro Marañón Sandra Saura-Mas Ricardo Díaz-delgado Rafael Villar Area de Ecología Facultad de CienciasUniversidad de Cordoba.14071 CordobaSpain CREAF Cerdanyola del Vallés08193 BarcelonaSpain Unitat d’Ecologia Dept.Biologia AnimalBiologia Vegetal i EcologiaUniversitat Autònoma BarcelonaEdifici CCampus UAB08193Cerdanyola del VallèsBarcelonaSpain IRNAS CSICAv.Reina Mercedes 10PO Box 1052.41080 SevillaSpain Estación Biológica de Doñana CSIC.c/Americo Vespucios/nIsla de la Cartuja.41092 SevillaSpain

Aims Extreme climatic events may have important consequences for plant community structure and *** 2005,a severe drought together with a cold winter promoted extensive damage and mortal-ity in shrubland communities of southwest Spain(Doñana National Park).Here,we aim to identify the mechanisms underlying commu-nity stability(resistance and resilience)in response to this extreme climatic event,considering changes in the functional structure of these *** We used a trait-based approach,quantifying variations in 10 func-tional traits at the community level(community weighted means,CWM)and the functional diversity(functional richness,evenness and divergence)in 18 plots at three different times:predating the climatic event(estimated from the sum of the live and dead volume of each species in 2007),and 2 and 8 years after the 2005 *** also quantified the differences in functional traits and functional diversity between adult and recruit stages,which allowed us to bet-ter understand the contribution of the recruitment to the mainte-nance of the functional structure and diversity of the *** Findings Communities with higher functional divergence before the cli-matic event maintained nearly constant their levels of functional divergence 8 years after,but they were more prone to changes in species *** resistance in terms of vegeta-tion cover was positively correlated with root dry matter content,whereas community resilience was positively correlated with leaf chlorophyll(LChl).We also found that some values(weighted means)of functional community traits(such as root dry matter con-tent and LChl)had increased 2 years after the event,returning to the pre-event conditions after 8 *** addition,there was hardly any establishment of new species in the community and the recruits did not make substantial differences to the community functional *** seed mass differed significantly between the adult and se

关键词： climate change Doñana drought functional trait recruitment resilience resistance

Synergism Effect between Phenolic Metabolites and Endogenous Antioxidants in Terms of Antioxidant Activity

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Advances in Chemical Engineering and Science 2014年第2期4卷 258-265页

作者： María Noguer Ana B. Cerezo M. Luisa Moyá Ana M. Troncoso M. Carmen García-Parrilla Nutrición y Bromatología Facultad de Farmacia Universidad de Sevilla Sevilla Spain

Polyphenolic compounds, widely distributed in plant kingdom, have been exhaustively studied for their bioactive properties specially antioxidant activity. However, they are extensively metabolized by human organism and the resulting metabolites are largely responsible for their effects. Furthermore, they may interact with the endogenous antioxidant network being this possibility scarcely studied. Plasma antioxidant network encompasses antioxidant enzymes and other substances such as uric acid. In addition, ascorbic acid is the major compound representing water soluble compartment both in foods and human body. The interaction of this vitamin with phenolic compound is largely unexplored. This work aims to study if there is a synergic effect between phenolic metabolites and main antioxidants (uric and ascorbic acid). For this purpose, the antioxidant activity was evaluated in terms of ORAC (oxygen radical absorbance capacity) and FRAP (ferricreducing antioxidant power) as these tests involved either HAT (Hydrogen Atom Transfer) or SET (Single Electron Transfer) mechanisms. Additionally, a kinetic studied was developed to test if the rate constant presented a synergic effect. Protocatechuic acid, 3,4-dihydroxyphenylacetic acid, 3,4-dihydroxyphenylpropionic acid and 3-hydroxyphenylacetic acid were selected as they were metabolites of polyphenol compounds such as anthocyanins, quercetin, neohesperidin, chlorogenic acid and hesperetin present in wines, orange and strawberries. A synergic effect was proved for the combination of ascorbic acid with 3,4-dihydroxyphenylacetic acid, both in terms of antioxidant activity and potent increase of velocity of the antioxidant reaction that took place.

关键词： Kinetics Ascorbic Acid Uric Acid ORAC FRAP

Best Simultaneous Approximation to Totally Bounded Sequences in Banach Spaces

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Acta Mathematica Sinica,English Series 2008年第9期24卷 1541-1554页

作者： Genaro LOPEZ department of Mathematical Analysis University of SevillaSevillaSpain

This paper is concerned with the problem of best weighted simultaneous approximations to totally bounded sequences in Banach spaces. Characterization results from convex sets in Banach spaces are established under the... 详细信息

关键词： best simultaneous approximation characterization uniqueness uniform smoothness

Hepatitis C virus genotype 3: Meta-analysis on sustained virologic response rates with currently available treatment options

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World Journal of Gastroenterology 2016年第22期22卷 5285-5292页

作者： Javier Ampuero K Rajender Reddy Manuel Romero-Gomez Inter-Centre Unit of Digestive Diseases and CIBERehd Virgen Macarena Virgen del Rocio University Hospitals University of Sevilla 41018 Sevilla Spain Instituto de Biomedicina de sevilla 41018 Sevilla Spain Division of Gastroenterology and Hepatology Department of Medicine University of Pennsylvania Philadelphia PA 19107 United States

AIM: To address the therapeutic efficacy of various treatment regimens in genotype 3 selecting randomized clinical trials and prospective National Cohort ***:(1) PEG-INF-based therapy including sofosbuvir(SOF) + RBV for 12 wk vs SOF + RBV 24 wk;(2) SOF + RBV therapy 12 wk/16 wk vs 24 wk; and(3) the role of RBV in SOF + daclatasvir(DCV) and SOF + ledipasvir(LDV) combinations. This metaanalysis provides robust information with the intention of addressing treatment strategy for hepatitis C virus genotype ***: A combination treatment including SOF + RBV + PEG-IFN for 12 wk notes better SVR than with only SOF + RBV for 12 wk, although its association with more frequent adverse effects may be a limiting factor. Longer duration therapy with SOF + RBV(24 wk) has achieved higher SVR rates than shorter durations(12 or 16 wk). SOF + LDV are not an ideal treatment for genotype 3. CONCLUSION: Lastly, SOF + DCV combination is probably the best oral therapy option and the addition of RBV does not appear to be needed to increase SVR rates substantially.

关键词： Hepatitis C Genotype 3 Sofosbuvir Daclatasvir Ledipasvir

Shallow water equations for power law and Bingham fluids dedicated to the NSFC-CNRS Chinese-French summer institute on fluid mechanics in 2010

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Science China Mathematics 2012年第2期55卷 277-283页

作者： FERNANdeZ-NIETO Enrique D. NOBLE Pascal VILA Jean-Paul departamento de Matemdtica Aplicada I Universidad de Sevilla 41012 Sevilla Spain Universite de Lyon Universitd Lyon1 Institut Camille Jordan UMR CNRS 520843 blvd du 11 novembre 1918 F-69622 ViUeurbanne Cedex France Institut de Mathdmatiques de Toulouse UMR CNRS 5219 INSA de Toulouse 135 avenue de Rangueil 31077 Toulouse Cedex 4 France

In this note, we provide a consistant thin layer theory for power law and Bingham incompressible fluids flowing down an inclined plane under the effect of gravity. The derivation of such equations is based on formal asymptotic expansions of solutions of Cauchy momentum equations in the shallow water scaling and in the neighbourhood of steady solutions so that we can close the average equations on the fluid height h and the total discharge rate q.

关键词： shallow water equations asymptotic analysis non-Newtonian fluids

Tests Management in CALIPSOneo: A Mde Solution

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Journal of Software Engineering and Applications 2014年第6期7卷 506-512页

作者： Alberto Salido Julian Alberto Garcia Garcia Jose Ponce Javier Jesus Gutierrez Software Engineering and Early Testing Group Universidad de Sevilla Sevilla Spain

Testing in Software Engineering is one of the most important phases although, unfortunately, it cannot be always successfully fulfilled due to time constraints. In most cases, the development phase takes more time than it was estimated, entailing negative effects on the testing phase. The delay increases even more in Research and development (R + D) projects, where the real time to execute tasks is more difficult to control. Model Driven Engineering (Mde) offers a solution to avoid testing costs without affecting the execution quality of the applied test. This paper presents a practical overview of a Model Driven Testing (MDT)-based methodology and its impact on CALIPSOneo project, which was carried out in liaison with Airbus defense and Space and, particularly, with the Product Lifecycle Management (PLM) department.

关键词： Model-Driven Testing Model-Driven Engineering Product Lifecycle Management

Opposed elevational variation in prevalence and intensity of endoparasites and their vectors in a lizard

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Current Zoology 2018年第2期64卷 197-204页

作者： Lola ALVAREZ-RUIZ Rodrigo MEGIA-PALMA Senda REGUERA Santiago Rulz Francisco J. ZAMORA-CAMACHO Jordi FIGUEROLA Gregorio MORENO-RUEDA Centro de Investigaciones sobre desertificacion-csic Ctra. Naquera Kin. 4.5 Moncada Valencia E-46113 Spain departarnento de Ecologia Evolutiva Museo Nacional de Ciencias Naturales-CSIC c/Jose Gutierrez Abascal Madrid E-28006 Spain Unit of Ethology and Animal Welfare Faculty of Veterinary University CEU Cardenal Herrera Alfara del Patriarca (Valencia) E-46113 Spain Servicio de Control de Mosquitos DiputaciGn Provincial de Huelva Centro de InvestigaciGn Biornedica en Red Epidemiologia y Salud Publica (CIBERESP) Huelva Spain CIBER de Epidemiologia y Salud Peblica (CIBERESP) Spain departamento de Biogeografia y Carnbio Global Museo Nacional de Ciencias Naturales-CSIC C/Jose Gutierrez Abascal 2 Madrid E-28006 Spain departarnento de Ecologia de Hurnedales Estacion Biologica de Dofiana-CSIC c/Americo Vespucio s/n Sevilla E-41092 Spain departamento de Zoologia Facultad de Ciencias Universidad de Granada Granada E-18071 Spain

Studying the causes of parasite geographic distribution is relevant to understand ecological and evolutionary processes that affect host populations as well as for species conservation. Temperature is one of the most important environmental variables affecting parasite distribution, as raising temperatures positively affect development, reproduction, and rate of transmission of both endo- and ectoparasites. In this context, it is generally accepted that, in mountains, parasite abundance decreases with elevation. However, empirical evidence on this topic is limited. In the present study, we analyzed the elevational variation of hemoparasites and ectoparasites of a lizard, Psammodromus algirus, along a 2,200-m elevational gradient in Sierra Nevada （SE Spain）. As pre- dicted, ectoparasite （mites, ticks, mosquitoes, and sandflies） abundance decreased with elevation. However, hemoparasite prevalence and intensity in the lizard augmented with altitude, showing a pattern contrary to their vectors （mites）. We suggest that tolerance to hemoparasites may increase with elevation as a consequence of lizards at high altitudes taking advantage of increased body condition and food availability, and reduced oxidative stress. Moreover, lizards could have been selected for higher resistance against hemoparasites at lowlands （where higher rates of replication are expected）, thus reducing hemoparasite prevalence and load. Our findings imply that, in a scen- ario of climate warming, populations of lizards at high elevation may face increased abundance of ectoparasites, accompanied with strong negative effects.

关键词： elevation immune system parasite distribution Psammodromus algirus reptile