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Neural Regeneration Research 2015年第10期10卷 1574-1575页

作者： Silvia Santamaria Jose A.Garcia-Sanz Department of Cellular and Molecular Medicine Centro de Investigaciones Biologicas (CIB-CSIC)

Similarly to other adult tissues,a hierarchical structure has been established for the brain,where the differentiated cell types（neurons,oligodendrocytes and astrocytes）are generated from primary progenitor cells,known as type B astrocytes or neural stem cells （NSC）, through one or multiple stages of amplification （transient amplifying cells） that generate precursor cells （iPC） with more restricted potential nlPCs （neural）, alPCs （astrocytes）, olPC （oligodendrocytes）（Kriegstein and Alvarez-Buvlla, 2009）.

关键词： NSCs stem

Calculation of the infrared frequency and the damping constant (full width at half maximum) for metal organic frameworks

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Chinese Physics B 2019年第6期28卷 324-331页

作者： M Kurt H Yurtseven A Kurt S Aksoy Department of Physics Canakkale 18 Mart University17100 CanakkaleTurkey Department of Physics Middle East Technical University06531 AnkaraTurkey Lapseki ICDAS cib MTAL High School 17100 CanakkaleTurkey

The ρ(NH2) infrared(IR) frequencies and the corresponding full width at half maximum(FWHM) values for(CH3)2 NH2 FeⅢ M Ⅱ(HCOO)6(DMFe M, M = Ni, Zn, Cu, Fe, and Mg) are analyzed at various temperatures by using the experimental data from the literature. For the analysis of the IR frequencies of the ρ(NH2) mode which is associated with the structural phase transitions in those metal structures, the temperature dependence of the mode frequency is assumed as an order parameter and the IR frequencies are calculated by using the molecular field theory. Also, the temperature dependence of the IR frequencies and of the damping constant as calculated from the models of pseudospin(dynamic disorder of dimethylammonium(DMA+) cations)–phonon coupling(PS) and of the energy fluctuation(EF), is fitted to the observed data for the wavenumber and FWHM of the ρ(NH2) IR mode of the niccolites studied here. We find that the observed behavior of the IR frequencies and the FWHM of this mode can be described adequately by the models studied for the crystalline structures of interest. This method of calculating the frequencies(IR and Raman) and FWHM of modes which are responsible for the phase transitions can also be applied to some other metal organic frameworks.

关键词： infrared(IR) frequency full width at half maximum(FWHM) phase transitions ρ(NH2) mode niccolites

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MilK Dreams

China International Business 2008年第10期 38-39页

作者： BENJAMIN SHAW cib went to press on September 21

Homegrown dairy giant Mengniu has achieved spectacular growth to date, but its implication in the melamine scandal raises questions about its future

关键词：奶制品行业蒙牛集团三聚氰胺食品安全企业发展

What＇s Behind the Jaw- Dropping Data？

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China International Business 2014年第9期 52-53页

作者： SHIN CHANRI The view of the author does notrepresent cib's stance.

In June, new RMB-denominated loans extended by Chinese banks came in at RMB1.08 trillion （US$173.9 billion）,beating market expectations of a little more than RMB900 billion, according to data published in mid-July by the People＇s Bank of China （PBOC）, the country＇s central bank. Broad money supply, M2, grew by 14.7% during the month, also significantly higher than the predicted 13.5%.

关键词：中国银行人民银行同比增长人民币供应量贷款美元

A New Species of the Asian Toad Genus Megophrys sensu lato(Amphibia: Anura: Megophryidae) from Guizhou Province, China

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Asian Herpetological Research 2018年第4期9卷 224-239页

作者： Shize LI Ning XU Jing LIU Jianping JIANG Gang WEI Bin WANG Department of Food Science and Engineering Maotai University CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization and Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of Biology (CIB) Chinese Academy of Sciences (CAS) Biodiversity Conservation Key Laboratory Guiyang College

We describe a new species of the genus Megophrys sensu lato from Guizhou Province, China. Molecular phylogenetic analyses based on mitochondrial DNA and nuclear DNA sequences all strongly supported the new species as an independent lineage in Megophrys(Panophrys) clade. The new species is distinguished from its congeners by a combination of the following morphological characteristics:(1) small body size with SVL < 38.8 mm in male and SVL < 42.3 mm in female;(2) vomerine teeth absent;(3) tongue not notched behind;(4) a small horn-like tubercle at the edge of each upper eyelid;(5) tympanum distinctly visible, rounded;(6) two metacarpal tubercles in hand;(7) relative finger lengths: II < I < V < III;(8) toes with rudimentary webbing at bases;(9) heels overlapping when thighs are positioned at right angles to the body;(10) tibiotarsal articulation reaching the level between tympanum to eye when leg stretched forward;(11) an internal single subgular vocal sac in male;(12) in breeding male, the nuptial pads with black nuptial spines on the dorsal bases of the first and second fingers.

关键词： Megophrys sensu lato new species taxonomy phylogenetic analysis Guizhou Province China

The impact of regulatory and financial discrimination on China's low-carbon development:Considering firm heterogeneity

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Advances in Climate Change Research 2020年第2期11卷 72-84页

作者： TANG Wei-Qi MENG Bo WU Li-Bo cib Research Shanghai200120China Center for Energy Economics and Strategy Studies Fudan UniversityShanghai200433China Institute of Developing Economies–JETRO Chiba2618545Japan Tokyo Foundation for Policy Research Tokyo1066234Japan School of Economics Fudan UniversityShanghai200433China

Firms in China within the same industry but with different ownership and size have different production functions and face different emission regulations and financial conditions,thus can give very different responses to environmental *** fact has been largely ignored in most of the low-carbon development related *** an augmented Chinese input–output table in which information about firm size(large-and small and medium-sized firms)and ownership(state-,foreign-,and private-owned firms)are explicitly reported,a dynamic computable general equilibrium model is developed in this study to analyze the impact of alternative low-carbon policy designs with different regulatory coverage and financial equalization on heterogeneous *** simulation results show that,with the fully balanced regulation coverage and equalized financial system for heterogeneous firms,the total green investment accounts for 4%of GDP in 2030 for fulfilling China's commitment to reduce carbon emissions,which is the lowest among the various scenarios;about one-third of this investment is made by small and private firms;at the same time,green investment efficiency will be the highest,about 84%higher than that of the business-as-usual ***,a market-oriented and new technology-driven arrangement and mechanism for sharing emission reduction burden and allocating green investment across heterogeneous firms,especially to small and medium-sized firms,is crucial for China to achieve a more ambitious emission target in the long run.

关键词： Small-and medium-sized enterprise(SME) Green finance Firm heterogeneity ETS CO2 emissions Low-carbon Chinese economy

Circulating microRNAs and liquid biopsy:murine xenograft models for technical validation of clinical protocols

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Journal of Cancer Metastasis and Treatment 2019年第6期4卷 87-97页

作者： Jessica Gasparello Matteo Allegretti Chiara Papi Elena Giordani Patrizio Giacomini Roberto Gambari Alessia Finotti Department of Life Sciences and Biotechnology Ferrara UniversityFerrara 44121Italy Oncogenomics and Epigenetics IRCCS Regina Elena National Cancer InstituteRome 00144Italy Interuniversity Consortium for Biotechnology(cib) Trieste 34149Italy

In oncology,liquid biopsy is applied to detect with high efficiency clinically relevant analytes,such as tumor cells,cell-free nucleic acids,and exosomes in peripheral blood and other body fluids of cancer *** biopsy is considered one of the most advanced non-invasive diagnostic systems useful,in the next future,for enabling personalized treatments in precision *** actions include,but are not limited to,early diagnosis,staging,prognosis,anticipation(lead time)and prediction of therapy responses,as well as follow *** system for validation of the proposed liquid biopsy approaches is highly *** this review article we will discuss the establishment of xenotransplanted mouse model systems for the validation of liquid biopsy protocols aimed to identify changes in the miRNA plasma *** colon cancer HT-29 and LoVo cells have been xenotransplanted and miR-221-3p and miR-222-3p have been comparatively analyzed in cultured HT-29 and LoVo cells,xenotransplants and plasma samples.

关键词： Liquid biopsy circulating tumor RNA microRNA xenograft

ACIDIC FIBROBLAST GROWTH FACTOR REDUCES RAT SKELETAL MUSCLE DAMAGE CAUSED BY ISCHEMIA AND REPERFUSION

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Chinese Medical Journal 1995年第3期 51-56页

作者：傅小兵 Cuevas P. Gimenez-Gallego G 盛志勇田惠民 Trauma Center Postgraduate Medical College 304th Hospital. Beijing 100037 Servicio de Histologia Hospital Universitario Ramony Cajal 28034-Madrid Spain cib-CSCI Velazquez 14428006-Madrid.Spain

Acute interruption of arterial blood flow to the extremities is often associated with significant morbidity and mortality. Broad spectrum mitogenic and non mitogenic activities of FGFs inspired us to study its protecting effects on tissue injuries in ischemia reperfusion condition. We found that systemic administration of aFGF after reperfusion onset prevented severe skeletal muscle injuries. In rats treated with aKGF, the tissue edema was reduced significantly, the tissue viability was increased, and the muscle fibers contained more succinate dehydrogenase (SDH) and adenosine triphosphatasc (ATPase). The pathological results supported the concept of improved prevention with aFGF treatment. The possible tissue protection by aFGF may come from its ability to regulate the concentration of evtra- and intracellular calcium ion. Besides, it may moderate other Ca2+ dependent enzyme conversion processes. Also, it may take part in the vascular tone regulation under ischemia and reperfusion conditions. These results suggest further study of tissue ischemia prevention with FGF and its possible mechanisms in the future.

关键词： aFGF ACIDIC FIBROBLAST GROWTH FACTOR REDUCES RAT SKELETAL MUSCLE DAMAGE CAUSED BY ISCHEMIA AND REPERFUSION

Peptide nucleic acid-based targeting of microRNAs:possible therapeutic applications for glioblastoma

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Journal of Cancer Metastasis and Treatment 2019年第7期4卷 28-40页

作者： Roberto Gambari Jessica Gasparello Alessia Finotti Department of Life Sciences and Biotechnology University of FerraraFerrara 44121Italy Interuniversity Consortium for Biotechnology(cib) Trieste 34149Italy.

A large and incremental number of non-coding RNAs, including microRNAs (miRNAs) have been recently demonstrated to play a very important role in human pathologies, including cancer. Therefore, microRNAs have been proposed as therapeutic targets and molecules exhibiting anti-miRNA activity or mimicking functional miRNAs have been developed. Among biomolecules proposed in anti-miRNA therapy, peptide nucleic acids (PNAs) are appealing, in consideration of their stability and efficacy in recognizing RNA targets. PNAs against tumor associated miRNAs have proven to be efficient in inducing anti-tumor effects both in vitro and in vivo. For instance, PNAs targeting miR-155-5p are able to induce apoptosis in glioma cell lines and to enhance the sensitivity to temozolomide (TMZ) in TMZ resistant glioma cells. In vivo, PNAs anti-miR-21 were found to exhibit anti-tumor effects associated with improved survival when administered to animals with intracranial gliomas.

关键词： Peptide nucleic acids glioma microRNAs miRNA targeting delivery apoptosis temozolomide

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建筑物结构火灾性能预测(英文)

消防科技 2004年第3期23卷 213-219页

作者： Richard W. Bukowski P.E. FSFPE Coordinator CIB W14 NIST Building and Fire Research Laboratory Gaithersburg Maryland 20899 USACoordinator CIB W14 NIST Building and Fire Research Laboratory Gaithersburg Maryland 20899 USA

回顾了建筑物结构火灾性能研究的历史 ,介绍了构件耐火试验和性能化防火的法则。

关键词：建筑物火灾耐火试验防火结构