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Genetic Variations and Nonalcoholic Fatty Liver Disease:Field Synopsis,Systematic Meta-Analysis,and Epidemiological Evidence

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Biomedical and Environmental Sciences 2024年第7期37卷 762-773页

作者： Yamei Li Xiang Xiao Jie Wang Yixu Liu Xiongfeng Pan Haibin Yu Jiayou Luo Miyang Luo Department of Epidemiology and health Statistics School of Public HealthUniversity of South ChinaHengyang 421001HunanChina Department of Maternal and Child health Xiangya School of Public HealthCentral South UniversityChangsha 410008HunanChina Supervision and Inspection Department of Shanghai healthcare Security bureau Shanghai 200003China Department of Epidemiology and health Statistics Xiangya School of Public HealthCentral South UniversityChangsha 410008HunanChina

Objective To systematically summarize the published literature on the genetic variants associated with nonalcoholic fatty liver disease(NAFLD).Methods Literature from Web of Science,PubMed,and Embase between January 1980 and September 2022 was systematically ***-analyses of the genetic variants were conducted using at least five data *** epidemiologic credibility of the significant associations was graded using the Venice *** Based on literature screening,399 eligible studies were included,comprising 381 candidate gene association,16 genome-wide association,and 2 whole-exome sequencing *** identified 465 genetic variants in 173 genes in candidate gene association studies,and 25 genetic variants in 17 genes were included in the *** meta-analysis identified 11 variants in 10 genes that were significantly associated with NAFLD,with cumulative epidemiological evidence of an association graded as strong for two variants in two genes(HFE,TNF),moderate for four variants in three genes(TM6SF2,GCKR,and ADIPOQ),and weak for five variants in five genes(MBOAT7,PEMT,PNPLA3,LEPR,and MTHFR).Conclusion This study identified six variants in five genes that had moderate to strong evidence of an association with NAFLD,which may help understand the genetic architecture of NAFLD risk.

关键词： Nonalcoholic fatty liver disease Genetic association study Genetic variant Systematic review Meta-analysis

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Avian influenza and gut microbiome in poultry and humans:A“One health”perspective

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Fundamental Research 2024年第3期4卷 455-462页

作者： Ling Zhang Erkai Zhou Ce Liu Xiaoyu Tian Baode Xue Kai Zhang Bin Luo Institute of Occupational health and Environmental health School of Public HealthLanzhou UniversityLanzhouGansu 730000China Department of Environmental health Sciences School of Public HealthUniversity at AlbanyState University of New YorkRensselaerNY 12144USA Shanghai Key Laboratory of Meteorology and health Shanghai Meteorological BureauShanghai 200030China Shanghai Typhoon Institute China Meteorological AdministrationShanghai 200030China

A gradual increase in avian influenza outbreaks has been found in recent *** is highly possible to trigger the next human pandemic due to the characteristics of antigenic drift and antigenic shift in avian influenza virus(AIV).Although great improvements in understanding influenza viruses and the associated diseases have been unraveled,our knowledge of how these viruses impact the gut microbiome of both poultry and humans,as well as the underlying mechanisms,is still ***“One health”approach shows better vitality in monitoring and mitigating the risk of avian influenza,which requires a multi-sectoral effort and highlights the interconnection of human health with environmental sustainability and animal ***,monitoring the gut microbiome may serve as a sentinel for protecting the common health of the environment,animals,and *** review summarizes the interactions between AIV infection and the gut microbiome of poultry and humans and their potential *** the presented suggestions,we hope to address the current major challenges in the surveillance and prevention of microbiome-related avian influenza with the“One health”approach.

关键词： Avian influenza AIV Poultry Gutmicrobiome One health Poultry-Environment-Human Interface

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An Analysis of the Low Moving Speed of Landfalling Typhoon In-Fa in 2021

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Journal of Tropical Meteorology 2024年第1期30卷 51-60页

作者：郑丽娜吕新刚李瑞 Jinan Meteorological bureau of Shandong Province Jinan 250102 China

The movement speed of Typhoon In-Fa(2021)was notably slow,at 10 km h-1or less,for over 20 hours following its landfall in Zhejiang,China,in contrast to other typhoons that have made *** study examines the factors contributing to the slow movement of Typhoon In-Fa,including the steering flow,diabatic heating,vertical wind shear(VWS),and surface synoptic situation,by comparing it with Typhoons Yagi(2018)and Rumbia(2018)which followed similar *** findings reveal that the movement speed of Typhoons Yagi and Rumbia is most closely associated with their respective 500 h Pa environmental winds,with a steering flow of 10^(-12)m s^(-1).In contrast,Typhoon InFa’s movement speed is most strongly correlated with the 850 h Pa environmental wind field,with a steering flow speed of only 2 m s^(-1).Furthermore,as Typhoon In-Fa moves northwest after landfall,its intensity is slightly greater than that of Typhoons Yagi and Rumbia,and the pressure gradient in front of Typhoon In-Fa is notably smaller,leading to its slow ***,the precipitation distribution of Typhoon In-Fa differs from that of the other two typhoons,resulting in a weak asymmetry of wavenumber-1 diabatic heating,which indirectly affects its movement *** analysis indicates that VWS can alter the typhoon’s structure,weaken its intensity,and ultimately impact its movement.

关键词： landfalling typhoon steering flow diabatic heating VWS

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Anomaly Detection Algorithm of Power System Based on Graph Structure and Anomaly Attention

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Computers, Materials & Continua 2024年第4期79卷 493-507页

作者： Yifan Gao Jieming Zhang Zhanchen Chen Xianchao Chen Zhaoqing Power Supply bureau of Guangdong Power Grid Co. Ltd.Zhaoqing526060China

In this paper, we propose a novel anomaly detection method for data centers based on a combination of graphstructure and abnormal attention mechanism. The method leverages the sensor monitoring data from targetpower substations to construct multidimensional time series. These time series are subsequently transformed intograph structures, and corresponding adjacency matrices are obtained. By incorporating the adjacency matricesand additional weights associated with the graph structure, an aggregation matrix is derived. The aggregationmatrix is then fed into a pre-trained graph convolutional neural network (GCN) to extract graph structure ***, both themultidimensional time series segments and the graph structure features are inputted into a pretrainedanomaly detectionmodel, resulting in corresponding anomaly detection results that help identify abnormaldata. The anomaly detection model consists of a multi-level encoder-decoder module, wherein each level includesa transformer encoder and decoder based on correlation differences. The attention module in the encoding layeradopts an abnormal attention module with a dual-branch structure. Experimental results demonstrate that ourproposed method significantly improves the accuracy and stability of anomaly detection.

关键词： Anomaly detection transformer graph structure

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Biochar Decreases Soil Cadmium(Cd) Availability and Regulates Expression Levels of Cd Uptake/Transport-Related Genes to Reduce Cd Translocation in Rice

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Rice science 2024年第5期31卷 494-498,I0006-I0013页

作者： WANG Han HUANG Qina ZHANG Yan SHAO Guosheng HU Yijun XU Youxiang China National Rice Research Institute Hangzhou 310006China Jiangshan Agriculture and Rural Affairs bureau Quzhou 324100China Longyou Agriculture and Rural Affairs bureau Quzhou 324400China

Biochar has been used as a soil amendment for heavy metal-contaminated soils, and it has the potential to mitigate Cd accumulation in plants. In this study, we used rice straw biochar(RSB) and kitchen waste biochar(KWB) to clarify the effect of biochar on Cd-contaminated neutral soil, the physiological responses to biochar application, and the gene regulatory networks in a rice genotype.

关键词： soil straw soils

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Effect of relative humidity on the desulfurization performance of calcium-based desulfurizer

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Journal of Environmental Sciences 2024年第4期138卷 179-188页

作者： Juan Lǖ Yu Fu Haiyan Yu HuanWang Zhe Wang Haiyan Chen School of Environment and Resource Southwest University of Science and TechnologyMianyang 621010China Guangyuan Emergency Management bureau Guangyuan 628000China

Low desulfurization efficiency impedes the wide application of dry desulfurization technology,which is a low-cost and simple process,and one significant solution is the development and manufacture of high-performance *** this study,firstly,a steam jet mill was used to digest quicklime;then,we utilized numerical simulation to study the flow field distribution and analyze the driving factors of quicklime digestion;and lastly,the desulfurization performance of the desulfurizer was evaluated under different relative *** results show that the desulfurizer prepared via the steam jet mill had better apparent activity than traditional ***,the entire jet flow field of the steam jet mill is in a supersonic and highly turbulent flow state,with high crushing intensity and good particle acceleration *** contact with the nascent surface maximizes the formation of slaked *** experiments demonstrated that the operating time with 100%desulfurization efficiency and the“break-through”time for the desulfurizer prepared via the steam jet mill is longer than that of traditional desulfurizers,and has significant advantages,especially at low flue gas relative *** with traditional desulfurizers,the desulfurizer prepared via steam jet mill expands the range of acceptable flue gas temperature,and the failure temperature is 1.625 times that of traditional *** work breaks through the technical bottleneck of low dry desulfurization efficiency,which is an important step in pushing forward the application of dry desulfurization.

关键词： Dry desulfurization Relative humidity Desulfurization efficiency High-efficiency desulfurizer Quicklime digestion

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Effects of urbanization and forest type on species composition and diversity,forest characteristics,biomass carbon sink,and their associations in Changchun,Northeast China:implications for urban carbon stock improvement

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Journal of Forestry Research 2024年第2期35卷 146-162页

作者： Yuanyuan Wang Xinzhu Dai Xingling Chen Dan Zhang Guiqing Lin Yuanhang Zhou Tianyi Wang Yulong Cui Academy of Forestry Sciences of Changchun Bureau of Forestry and Landscaping of ChangchunChangchun 130117People’s Republic of China College of Landscape Architecture Changchun UniversityChangchun 130022People’s Republic of China Changchun South Lake Park Bureau of Forestry and Landscaping of ChangchunChangchun 130012People’s Republic of China

Differences in forest attributes and carbon sequestration of each organ and layer between broadleaved and conifer forests of central and outer urban areas are not well-defined,hindering the precise management of urban forests and improvement of *** clarify the effect of two forest types with different urbanization intensities,we determined differences in vegetation composition and diversity,structural traits,and carbon stocks of 152 plots(20 m×20 m)in urban park forests in Changchun,which had the largest green quantity and carbon density *** found that 1.1-fold thicker and healthier trees,and 1.6-to 2.0-fold higher,healthier,denser,and more various shrubs but with sparser trees and herbs occurred in the central urban forests(phealthier and more diverse trees were found in broadleaved forests of both the inner and outer forests(p<0.05).Plant size and dominant species had similarly important roles in carbon stock improvement,especially big-sized woody plants and Pinus *** addition,a higher number of deciduous or needle species positively affected the broadleaved forest of the central urban area and conifer forest of the outer urban area,*** findings can be used to guide precise management and accelerate the improvement of urban carbon function in Northeast China in the future.

关键词： Species diversity Forest characteristics Biomass carbon sink Forest-type effect Urbanization effect Urban forests

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Microphysical Insights into a Tornadic Supercell from Dual-Polarization Radar Observations in Jiangsu, China on 14 May 2021

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Journal of Meteorological Research 2024年第2期38卷 303-320页

作者： Chao YUAN Yang BAI Pengfei SUN Hua BAI Lu XIA China Meteorological Administration Tornado Key Laboratory Foshan 528315 Institute of Atmospheric Environment China Meteorological AdministrationShenyang 110166 Panjin National Climate Observatory Panjin 124010 Yangzhou Meteorological bureau of Jiangsu Province Yangzhou 225100 Yichun Meteorological bureau of Heilongjiang Province Yichun 153000

Tornadoes are incredibly powerful and destructive natural events,yet the microphysical characteristics of the parent storm and its effects on tornadogenesis remain *** study analyzed polarization radar data of a tornadic supercell that occurred in Jiangsu Province of China on 14 May 2021,in comparison with another tornadic supercell and two non-tornadic supercells that occurred in the same region in *** two tornadic supercells exhibited lower differential reflectivity(ZDR)in the hook echo region compared with the non-tornadic supercells,indicating smaller median drop sizes.A distinct increase in ZDR from the melting of frozen hydrometeors,observed between2.5-and 4.0-km altitude in the non-tornadic storms,was absent in the tornadic *** non-tornadic supercells also displayed substantially higher specific differential phase(KDP)below the melting level,likely aroused from enhanced melting and *** findings suggest fundamental microphysical contrasts between tornadic and nontornadic ***,tornadic supercells have smaller droplets and may reduce melting in hook ***,greater separation between the ZDR arc and the KDP foot was observed during *** vertical gradient of KDP related to the cooling pool strength of the hook echo,regulating rear-flank downdraft *** the limited number of cases investigated,the findings of this study indicate that monitoring ZDR,KDP,and drop size distribution trends could assist with tornado prediction and warnings.

关键词： tornado polarimetric radar supercell hook echo drop size distribution

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Comparison of toxicity between lanthanum oxide nanoparticles and lanthanum chloride

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Journal of Rare Earths 2024年第2期42卷 424-430,I0007页

作者： Kun Huang Songchang Lai Miao Guo Xingwu Zhu Jiashuangwei Yuan Zhehao Liu Gonghua Hu Yanfang Gao School of Public health and health Management Gannan Medical UniversityGanzhou341000China

Due to the wide application of rare earth elements,lanthanum(La) is gradually accumulated in our living *** can enter the body through a variety of routes,which has a series of effects on various *** a consequence,the safety of lanthanum deserves our *** study aims to compare the toxicity of lanthanum oxide nanoparticles(La_(2)O_(3) NPs) and lanthanum chloride(LaCl_(3)) and enrich the toxicity evaluation of ***,a 30 d intragastal experiment was conducted.C57BL/6j mice were given by La_(2)O_(3) NPs solution and LaCl_(3) solution respectively at doses of 0,30,60 and120 mg/kg BW(lanthanum content).The results show that,compared with the control group,both La_(2)O_(3)NPs and LaCl_(3) can reduce the body weight of female mice in the high-dose group,but for male mice,the high-dose La_(2)O_(3) NPs solution can increase the body weight,while LaCl_(3) has the opposite *** coefficients of liver,kidney,heart,lung,uterine and ovaries increase first and then decrease with the exposure dose,but testes and epididymides coefficient keep increasing with the exposure of LaCl_(3) and La_(2)O_(3) ***_(2)O_(3) NPs and LaCl_(3) can reduce the concentration of triglycerides(TG) and increase the level of low density lipoprotein(LDL),but the effect of La_(2)O_(3) NPs is more ***_(2)O_(3) NPs and LaCl_(3) can reduce the concentration of malondialdehyde(MDA),increase the total antioxidant capacity(T-AOC)and enhance the activity of catalase(CAT),but LaCl_(3) has more obvious protective effects on oxidative ***_(2)O_(3) NPs and LaCl_(3) have potential risks to liver,and the toxicity of La_(2)O_(3) NPs might be higher than that of LaCl_(3).

关键词： Rare earth elements Lanthanum oxide nanoparticles Lanthanum chloride Lipid metabolism Oxidative stress

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NiO-Doped Fe_(2)O_(3)/MgO Properties for the Chemical Looping Oxidative Dehydrogenation of Ethane

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China Petroleum Processing & Petrochemical Technology 2024年第1期26卷 27-33页

作者： Liang Hao Chen Junjie Sun Jie Sun Hui Shenyang Ligong University Shenyang 110159China Fushun Ecology Environment bureau Qingyuan County Branch Fushun 113399China

Ethane chemical looping oxidative dehydrogenation(CL-ODH)to ethylene is a new technology for ethylene ***_(2)O_(3)/MgO oxygen carrier was prepared using the co-precipitation *** influence of added NiO and its different loadings on Fe_(2)O_(3)/MgO were ***,a series of oxygen carriers were applied in the CL-ODH of the ethane cycle ***-Emmett-Teller(BET),X-ray diffractometry(XRD),X-ray photoelection spectroscopy(XPS),and H2-temperature programmed reduction(TPR)were used to characterize the physicochemical properties of these oxygen *** was confirmed that an interaction between NiO and Fe_(2)O_(3) occurred based on the XPS and H2-TPR *** on the CL-ODH activity performance tests conducted in a fixed-bed reactor,it was revealed that ethylene selectivity was significantly improved after NiO ***_(2)O_(3)-10%NiO/MgO showed the best activity performance with 93%ethane conversion and 50%ethylene selectivity at a reaction temperature of 650℃,atmospheric pressure,and space velocity of 7500 mL/(g·h).

关键词： chemical looping oxidative dehydrogenation oxygen carrier Fe_(2)O_(3)/MgO NiO

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