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80～89岁患者和90～99岁患者接受较大选择性妇科手术的结局

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世界核心医学期刊文摘（妇产科学分册） 2006年第12期2卷 13-13页

作者： Friedman W.H. Gallup D.G. Burke II J.J. 王淑珍 department of Obstetrics and Gynecology Memorial Health University Medical Center (MHUMC)SavannahGAUnited States Dr.

Objective:The purpose of this study was to determine whether age is a risk factor for perioperative and postoperative complications. Study design:This was a retrospective case-control study of 120 women over age 79 (group 1) compared with 1,497 younger patients 50-79 (group 2) undergoing major elective gynecologic surgery. Results:Mean length of stay was 4.8 days for group 1,compared with 3.8 for group 2 (P = .018). Patients hospitalized longer than 1 week was higher (P gynecologic surgery.

关键词：低血容量性休克脓毒症术后并发症围手术期泌尿道感染呼吸衰竭病例对照研究研究设计

在压力性尿失禁妇女外科手术队列中与尿失禁频率相关的因素

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世界核心医学期刊文摘（妇产科学分册） 2006年第8期2卷 11-11页

作者： Richter H.E. Burgio K.L. Brubaker L. 党慧敏 department of Obstetrics and Gynecology Division of Medical Surgical Gynecology University of Alabama at Birmingham Birmingham AL United States Dr.

Objective: The aim of this study was to identify factors associated with urinary incontinence severity at baseline in women undergoing surgery for stress incontinence. Study design: Baseline data were obtained from 650 women (age 28 to 81 years) with stress incontinence participating in a randomized surgical trial. Severity of incontinence was defined by the mean number of incontinence episodes per day recorded in a 3- day bladder diary. The relationships between severity and several baseline variables were examined, including demographics, medical, obstetric, and gynecologic history, body mass index, smoking status, Q- tip displacement, and Pelvic Organ Prolapse Quantification stage (POP- Q). Results: In a multivariable model, severity of incontinence was positively associated with body mass index (P = .0003) and current smoking (P = .01), and negatively associated with prolapse stage (P < .0001) and Qtip displacement (P = .042). Conclusion: Incontinence severity in a surgical population was independently associated with 2 modifiable factors, obesity and tobacco use, as well as pelvic support.

关键词：压力性尿失禁外科手术频率相关盆腔器官脱垂基线数据妇科学多变量模型产科学统计学特征吸

siRNA干扰UBCH10表达对乳腺癌细胞的影响

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外科理论与实践 2009年第6期14卷 652-655页

作者：王银平孙婧璟陈雪华俞佩琴刘炳亚上海复旦大学医学院附属华山医院南汇分院外一病区上海201300 department of Genitourinary Medical Oncology M.D.Anderson Cancer CenterUniversity of Texas 上海交通大学医学院附属瑞金医院消化外科研究所上海200025

目的:探讨UbcH10在乳腺癌细胞系MCF-7中的作用及机制。方法:使用UbcH10 siRNA干扰乳腺癌细胞系MCF-7中UbcH10的表达,并采用MTT法检测干扰后细胞的增殖变化,同时用流式细胞仪比较干扰后细胞周期的变化。结果:与正常空白对照组及siRNA阴... 详细信息

目的:探讨UbcH10在乳腺癌细胞系MCF-7中的作用及机制。方法:使用UbcH10 siRNA干扰乳腺癌细胞系MCF-7中UbcH10的表达,并采用MTT法检测干扰后细胞的增殖变化,同时用流式细胞仪比较干扰后细胞周期的变化。结果:与正常空白对照组及siRNA阴性对照组比较,siUbcH10干扰组细胞增殖明显受抑制,转染后48h,细胞周期中G2/M期细胞比例明显增加(空白对照组9.98%,阴性对照组8.32%,干扰组18.18%)。结论:UbcH10在乳腺癌细胞周期G2/M期中发挥重要作用,抑制MCF-7中UbcH10的表达可明显抑制乳腺癌细胞增殖,UbcH10有望成为乳腺癌靶向治疗中新的潜在靶点。

关键词：乳腺癌 UbcH10 siRNA 细胞周期

保乳手术至术后放疗的间隔时间对老年乳腺癌患者局部复发的影响：回顾性队列分析（摘要）

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英国医学杂志中文版 2010年第5期13卷 305-306页

作者： Rinaa S Ptmglia Aldko M Saito Bridget A Neville Craig C Earle Jane C Weeks 刘雨桃(译) 王燕(校) Departmcnt of Radiation Oneology Dana-Farber Cancer Institute Boston MA 02115 USA department of Medical Oncology Dana-Father Cancer Institute Boston Laboratory of Clinical Epideraiological and Health Services Research Clinical Research Center National Hospital Organization Nagoya Medical Center Aichi Japan Institute for Cainical Evaluative Sciences Toronto ON Canada 中国医学科学院肿瘤医院内科

目的探讨保乳手术至术后开始放疗的间隔时间长短是否对老年乳腺癌患者局部复发产生影响，以及可能引起放疗推迟的原因。

关键词：乳腺癌患者术后放疗局部复发间隔时间保乳手术队列分析老年摘要

应用超声对乳腺癌术后局部淋巴结复发进行监测

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国际医学放射学杂志 2009年第6期 572-572页

作者： H.JungMoon M.J.Kim E.K.Kim B.W.Park J.H.Youk J.Y.Kwak 邓怀福 department of Radiology Research Institute of Radiological ScienceYonsei University College of Medicine134 Shinchon-dongSeodaemun-guSeoul 120-752 South Korea

目的研究超声对乳腺癌术后腋窝淋巴结(lymphnode recurrence,LNR)及锁骨上淋巴结复发的监测诊断指标,并评价双侧乳腺超声检查中进行淋巴结检测对预后的评估价值。材料与方法此项回顾性研究经伦理委员会批准,并免除知情同意。自2003年1月—

关键词：乳腺癌术后远处转移病人淋巴结淋巴组织乳腺超声

术前MR成像乳腺实质背景信号强化率:与导管原位癌病人保乳术后局部复发的关系

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国际医学放射学杂志 2014年第3期 272-272页

作者： S.A.Kim N.Cho E.B.Ryu M.Seo M.S.Bae J.M.Chang 郭小超 department of Radiology Seoul National University College of Medicine Seoul National University Hospital 101 Daehak-roJongno-guSeoul 110-744Republic of Korea

摘要目的回顾性研究乳腺导管原位癌(DCIS)病人术前动态增强MR成像肿瘤周围实质背景特点与保乳术后同侧肿瘤复发(IBTR)-无病生存期是否存在相关性。材料与方

关键词：乳腺实质保乳术 DCIS 术前 MR 病人

HIV患者的浸润性外阴癌:病例报道及文献回顾

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世界核心医学期刊文摘（妇产科学分册） 2005年第10期1卷 47-47页

作者： Elit L Voruganti S Simunovic M 侯巍 department of Obstetrics and Gynecology McMaster University Juravinski Cancer Centre 699 Concession Street Hamilton Ont. L8V 5C2 Canada

Background. HIV is associated with a decrease in cellular immunity which allows for persistence of high- risk HPV types and this can predispose the woman to dysplasia or cancer of the gynecologic tract. Case. We present a case of Stage 3 vulvar cancer in a 33- year- old HIV positive woman. The patient was treated with primary radiation; unfortunately there was persistent disease. Exenterative surgery was planned but abandoned due to a positive presacral node. Conclusion. The optimal treatment of advanced vulvar cancer in HIV positive patients remains unclear given the small number of cases reported in the literature. Lessons from the anal cancer literature may help inform the care of vulvar cancer patients given the comparable high prevalence of this disease in the patients infected with HIV.

关键词：浸润性外阴癌 HIV患者文献回顾高危型淋巴结转移最佳治疗方案细胞免疫性易