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Treatment and prevention of diabetes complicated with non-alcoholic fatty liver disease by integrated traditional Chinese and Western medicine

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TMR Integrative Medicine 2023年第27期7卷 1-9页

作者： Xu He Xiu-Ping Chen Qi He Zhong-Fa Wang Jian-Hua Zhong Kui Wang Guangdong Provincial center of Integrated Traditional Chinese and Western Medicine for Metabolic diseases Guangdong Pharmaceutical UniversityGuangzhou 514000China Integrated Traditional Chinese and Western Medicine Internal Medicine center Dingnan Southern Integrated Chinese and Western Medicine HospitalGanzhou 341900China Department of Integrated Traditional Chinese and Western Medicine Rehabilitation Jiangxi Province Leping Traditional Chinese Medicine HospitalLeping 333300China Department of Integrated Traditional Chinese and Western Medicine for Geriatric diseases Guangxi Shanglin Limin HospitalNanning 530500China Department of Cardiovascular Medicine Poyang Lake Hospital Affiliated to Fuzhou Medical CollegeNanchang UniversityShangrao 333100China

Today’s social economy and science and technology levels are developing *** 2 diabetes mellitus(T2DM)is increasing in incidence,and T2DM promotes non-alcoholic fatty liver disease(NAFLD)through some *** pathogenesis of T2DM and NAFLD is interconnected,interacted with,and *** increasing the economic burden on patients,it also affects the quality and life of patients *** the world,the current treatment methods include exercise and diet control,drugs(including sugar reduction,lipid-lowering drugs,etc.),weight loss surgery,etc.,but currently,researching drugs can only control the progress of the *** present,there is no drug for T2DM combined with NAFLD ***,it is necessary to find and study effective drugs for *** on the principle of“syndrome differentiation,”traditional Chinese medicine(TCM)played an important role in treating this *** theory of TCM believes that the cause of NAFLD is mostly diet disorders and imbalances in daily life,leading to liver Qi stagnation,spleen dysfunction,and liver and kidney deficiency,producing phlegm and *** the treatment process,we must pay attention to the goal of phlegm turbidity,but also pay attention to the source of phlegm turbidity,strengthen the spleen and stomach,nourish the liver and kidney,and restore the physiological function of the *** ingredients of Chinese medicine extracts have the effects of antagonist oxidation stress,protecting liver cells,improving fibrous soluble systems,and promoting lipid metabolism,thereby reducing inflammatory factors to release damage to liver *** combining the diagnosis of TCM syndromes with Western medical disease diagnosis,the model of disease diagnosis combined with syndrome differentiation can compensate for some of the limitations of TCM’s sole reliance on syndrome differentiation,allowing for a better grasp of the *** treatment,a dual approach using traditional Chinese and Western me

关键词： traditional Chinese and Western medicine non-alcoholic fatty liver disease type 2 diabetes mellitus

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The etiology,clinical features and medical treatment of somatotroph adenomas

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Journal of Translational Neuroscience 2018年第1期3卷 23-31页

作者： Hua Gao Jianhua Li Yazhuo Zhang Key Laboratory of Central Nervous System Injury Research Beijing Neurosurgical Institute Capital Medical UniversityBeijing 100050 China Department of Neurosurgery Binzhou People’s Hospital Binzhou Shandong 256610 China Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Beijing Neurosurgical Institute Center of Brain Tumor Beijing Institute for Brain Disorder Capital Medical UniversityBeijing 100050 China

Somatotroph adenomas lead to hypersecretion of growth hormones(GH)and may cause mass *** with somatotroph adenomas may present with acral and soft tissue enlargement,joint pain,heart and respiratory failure,diabetes mellitus and hypertension,resulting in increased morbidity and *** diagnosis and treatment are therefore important in prolonging life and improving quality of *** studies depicted the landscape of genetic and epigenetic changes in sporadic somatotroph *** approaches are being developed for genetic testing,diagnosis and surveillance,which are helpful in early diagnosis,treatment and disease control of somatotroph *** suggest that patients with somatotroph adenomas are best treated with multidisciplinary teams composed of neuro-endocrinologists,neurosurgeons,radiation oncologists and other *** mini-review summarizes in a concise way the up-to-date discussion on the etiology,new diagnostic techniques and novel treatments of somatotroph adenomas.

关键词： somatotroph adenomas growth hormone(GH) somatic mutation apparent genetics treatment management

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Capsule endoscopy:Future horizons

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World Journal of Gastrointestinal Endoscopy 2010年第9期2卷 305-307页

作者： Zvi Fireman Department of Gastroenterology Hillel-Yaffe Medical Center Faculty of Medicine The Technion-Institute of TechnologyThe Rappaport Faculty of Medicine

Capsule endoscopy(CE) was launched at the beginning of this millennium and has since become a well established methodology for evaluating the entire small bowel for manifold *** far exceeded early expectations by providing a tool for establishing the correct diagnosis for elusive gastrointestinal(GI) conditions such as obscure GI bleeding,Crohn's disease,polyposis syndrome and *** CE,like radiology,gives results that can only be read,unlike conventional endoscopic procedures which enable concomitant biopsy when *** is one of the major limitations of the *** ideal CE should improve the quality of the image and have a faster frame rate than the currently available *** should be a therapeutic capsule capable of performing a biopsy,aspirating fluid,delivering drugs as well as measuring the motility of the small bowel *** major leap forward would be the capability of remote control of the capsule's movement in order to navigate it to reach designated anatomical areas for carrying out a variety of therapeutic *** for improving the capability of the future generation capsule is almost within grasp and it would not be surprising to witness the realization of these giant steps within the coming decade.

关键词： Capsule endoscopy Small bowel Therapeutic capsule Ideal capsule Biopsy Navigation

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Cutaneous leishmaniasis in Louisiana-one-year follow-up:A case report

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World Journal of Clinical Infectious diseases 2021年第1期11卷 19-26页

作者： Ashaur Azhar Hillary E Connell Christopher Haas Jelena Surla Devin Reed Sanjay Kamboj Gordon L Love Yussef Bennani Department of Medicine Section of Infectious DiseasesLouisiana State University Health Sciences CenterSchool of MedicineNew OrleansLA 70112United States Department of Medicine Louisiana State University Health Sciences CenterSchool of MedicineNew OrleansLA 70112United States Department of Dermatology Louisiana State University Health Sciences CenterSchool of MedicineNew OrleansLA 70112United States Jack Perry Strong Professor and Chair Department of PathologyLouisiana State University Health Sciences CenterSchool of MedicineNew OrleansLA 70112United States

Reports of leishmaniasis are scarce in North *** is considered to be one of the neglected tropical *** is seen in immigrants from endemic areas to United *** are not readily available in the United *** or inadequately treated cutaneous leishmaniasis not only causes localized disfigurement but can advance to more permanent and devastating mucosal disfigurement and perforation,if caused by a species that can also cause mucocutaneous *** SUMMARY A 42-year-old human immunodeficiency virus negative male immigrant from Honduras presented to the emergency department of our facility in Louisiana with a 2-mo history of a left lower extremity *** started as a painless blister that progressed in size and developed into other smaller lesions tracking up the thigh and became tender and *** looked nontoxic and *** was *** tests,except inflammatory markers,were within normal *** cellulitis of the leg was treated with 6 d of vancomycin that also relieved the *** biopsy was obtained,and histopathology was suspicious for *** chain reaction/deoxyribonucleic acid sequencing done by centers for disease control and prevention confirmed the diagnosis as Leishmania *** was no involvement of nasooropharyngeal mucosa,confirmed by *** patient was treated with miltefosine for 28 *** follow-up after approximately 11 mo revealed a healed skin *** Cutaneous leishmaniasis should be in the differential diagnosis of skin ulcers of travelers from endemic *** regarding diagnosis and treatment of leishmaniasis needs to be enhanced.

关键词： Cutaneous leishmaniasis Neglected diseases Leishmania(Viannia)panamensis Miltefosine Leishmania Case report

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Papillary thyroid cancer and inflammatory bowel disease:Is there a relationship?

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World Journal of Gastroenterology 2013年第7期19卷 1079-1084页

作者： Irene S Sonu Wojciech Blonski Ming Valerie Lin James Lewis Faten Aberra Gary R Lichtenstein Division of Internal Medicine Stanford University Hospital and ClinicsStanfordCA 94305United States Division of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Division of Digestive diseases University of CincinnatiCincinnatiOH 45229United States Division of Gastroenterology Hospital of the University of PennsylvaniaUniversity of Pennsylvania School of MedicinePhiladelphiaPA 19103United States

AIM:To formally study age of diagnosis of papillary thyroid cancer(PTC) in inflammatory bowel disease(IBD) patients and evaluate the prevalence of PTC in IBD patients compared to a control *** that patients with IBD are more likely to be diagnosed with PTC than a control population.A retrospective cohort analysis was performed using the University of Pennsylvania Health System's electronic *** from 1998-2009 were included in the search,and patients in the cohort were selected based on ICD-9 *** criteria included the diagnosis of Crohn's disease(CD) or ulcerative colitis(UC) and the concurrent diagnosis of thyroid cancer in comparison to a control *** these methods 912 patients with CD and 1774 with UC were compared to 1638 diverticulitis and 19 447 asthma *** were performed using corrected chisquare *** primary outcome for this study was the diagnosis of *** to conduct this study was obtained by the Institutional Review Board at the University of ***:The mean age was 47.5 years(range:18-102 years) and 66% patients were *** analysis of variance model was used to compare the age of PTC diagnosis between the CD,UC,asthma and diverticulitis groups,and a statistically significant difference in age at PTC diagnosis was noted across all groups(F = 6.35,df = 3,P = 0.0006).The age of PTC diagnosis in CD patients was statistically significantly lower than UC,asthma,and diverticulitis patients(average PTC diagnosis age for CD 25,UC 49,asthma 45,diverticulitis 63).After covarying for sex and age in 2009,the difference in age at PTC diagnosis remained statistically significant(F = 4.13,df = 3,P = 0.0089).A total of 86 patients were diagnosed with *** patients(0.5%) with UC were diagnosed with *** with UC were not shown to be more likely to develop PTC [odds ratio(OR):1.544,95%CI 0.767-3.108] compared to asthma *** patients(0.4%) with CD were

关键词： Papillary thyroid cancer Inflammatory bowel disease Crohn disease Ulcerative colitis

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Trend in the incidence and geographic variations of acute lymphoblastic leukemia in Shanghai, China from 2002 to 2006

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Chinese Medical Journal 2011年第16期124卷 2406-2410页

作者： NI Xiong SHEN Zhi-xiang CHEN Fang-yuan LIANG Hui LU Feng-juan CHEN Jing WANG Chun SHAO Jing-bo HOU Jian ZOU Shan-hua WANG Jian-min Department of Hematology Changhai Hospital Second Military Medical University Shanghai 200433 .China Department of Hematology Shanghai Ruijin Hospital Shanghai200025 China Department of Hematology Shanghai Renji Hospital Shanghai200127 China Department of Hematology Shanghai Xinhua Hospital Shanghai200092 China Department of Hematology Shanghai Children's Medical CenterShanghai 200127 China Department of Hematology Shanghai Children's Hospital of Fudan University Shanghai 200032 China Department of Hematology Shanghai First People's HospitalShanghai Jiao Tong University Shanghai 201620 China Department of Hematology Shanghai Children's Hospital ofShanghai Jiao Tong University Shanghai 200040 China Department of Hematology Changzheng Hospital SecondMilitary Medical University Shanghai 200003 China Department of Hematology Shanghai Zhongshan HospitalShanghai 200032 China

Background Great advances have been made in the diagnosis, molecular pathogenesis and treatment of acute lymphoblastic leukemia （ALL） in the past decade. Due to the lack of large population-based studies, the recent trends in the incidence and geographic variations of ALL in Shanghai, China have not been well documented. To better understand the incidence and epidemiological features of ALL in Shanghai, we conducted a retrospective survey based on the database from the Shanghai center for disease control and Prevention （CDC） and the medical records in all large-scale hospitals in Shanghai, especially those 30 major hospitals with hematology department. Methods According to the data from Shanghai CDC, 544 patients, with a median age of 32 years （ranging 1.2-89 years）, were diagnosed as de novo ALL from January 1, 2002 to December 31, 2006, and they were followed up until December 31,2007. Results The average annual incidence of ALL in Shanghai was 0.81/100 000. The incidence in men （0.86/100 000） was slightly higher than that in women （0.75/100 000）. The age-stratified incidence showed that the incidence was 2.31/100 000 in patients 〈17 years old, 0.54/100 000 in those 18-34 years old, 0.46/100 000 in those 35-59 years old, and 0.94/100 000 in those 〉60 years old. Moreover, there were substantial geographic variations in the incidence of ALL, with the incidence in Chongming county, an island in the east of Shanghai city being 0.60/100 000, much lower than those of other districts. Both French-American-British （FAB） and World Health Organization （WHO） classification systems were applied in the present study. Eighty-eight patients were diagnosed as L1 （26.2%）, 193 L2 （57.4%）, and 55 L3 （16.4%）. For 302 patients with immunophenotypic results, 242 were identified as B cell origin （80.1%）, 59 as T cell origin （19.5%）, and 1 as biphenotype （0.4%）. The leukemia cells in 61 patients co-expressed one or two myeloid antigen （20.2%）. For 269 patients with cytogenetic results, t

关键词： acute lymphoblastic leukemia epidemiology incidence

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Imaging in the COVID-19 era:Lessons learned during a pandemic

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World Journal of Radiology 2021年第6期13卷 192-222页

作者： Georgios Antonios Sideris Melina Nikolakea Aikaterini-Eleftheria Karanikola Sofia Konstantinopoulou Dimitrios Giannis Lucy Modahl Department of Radiology University of Massachusetts Medical SchoolBaystate Medical CenterSpringfieldMA 01199United States Group Society of Junior DoctorsAthens 11527Greece Division of Pulmonary Medicine Department of PediatricsSheikh Khalifa Medical CityAbu Dhabi W13-01United Arab Emirates Institute of Health Innovations and Outcomes Research The Feinstein Institutes for Medical ResearchNorthwell HealthManhassetNY 11030United States

The first year of the coronavirus disease 2019(COVID-19)pandemic has been a year of unprecedented changes,scientific breakthroughs,and *** radiology community has not been spared from the challenges imposed on global healthcare *** has played a crucial part in tackling this pandemic,either by demonstrating the manifestations of the virus and guiding patient management,or by safely handling the patients and mitigating transmission within the *** modifications involving all aspects of daily radiology practice have occurred as a result of the pandemic,including workflow alterations,volume reductions,and strict infection control *** the ongoing challenges,considerable knowledge has been gained that will guide future *** aim of this review is to provide the latest evidence on the role of imaging in the diagnosis of the multifaceted manifestations of COVID-19,and to discuss the implications of the pandemic on radiology departments globally,including infection control strategies and delays in cancer ***,the promising contribution of artificial intelligence in the COVID-19 pandemic is explored.

关键词： COVID-19 Infectious diseases Diagnostic imaging Radiography Computed tomography Artificial intelligence

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Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey

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Military Medical Research 2020年第4期7卷 418-429页

作者： Ying-Hui Jin Qiao Huang Yun-Yun Wang Xian-Tao Zeng Li-Sha Luo Zhen-Yu Pan Yu-Feng Yuan Zhi-Min Chen Zhen-Shun Cheng Xing Huang Na Wang Bing-Hui Li Hao Zi Ming-Juan Zhao Lin-Lu Ma Tong Deng Ying Wang Xing-Huan Wang center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan University169 Donghu RoadWuchang DistrictWuhan 430071HubeiChina Department of Evidence-Based Medicine and Clinical Epidemiology The Second Clinical CollegeWuhan UniversityWuhan 430071HubeiChina Division of Medical Affairs Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina Department of Hepatopancreatobiliary Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina Division of Social and Medical Development Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina Department of Respiratory Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina School of Nursing and Health Henan UniversityKaifeng 475000HenanChina Institute of Evidence-Based Medicine and Knowledge Translation Henan UniversityKaifeng 475000HenanChina Department of Infectious diseases Zhongnan Hospital of Wuhan UniversityWuhan 430071HubeiChina Leishenshan Hospital in Wuhan Wuhan 430200HubeiChina

Background:Many healthcare workers were infected by coronavirus disease 2019(COVID-19)early in the epidemic posing a big challenge for epidemic ***,this study aims to explore perceived infection routes,influencing factors,psychosocial changes,and management procedures for COVID-19 infected healthcare ***:This is a cross-sectional,single hospital-based *** recruited all 105 confirmed COVID-19 healthcare workers in the Zhongnan Hospital of Wuhan University from February 15 to 29,*** participants completed a validated *** consent was obtained from all *** causes of infection,infection prevention,control knowledge and behaviour,psychological changes,symptoms and treatment were ***:Finally,103 professional staff with COVID-19 finished the questionnaire and was included(response rate:98.1%).Of them,87 cases(84.5%)thought they were infected in working environment in hospital,one(1.0%)thought their infection was due to the laboratory environment,and 5(4.9%)thought they were infected in daily life or community *** of throat collection and physical examination were the procedures perceived as most likely causing their infection by nurses and doctors ***-three(41.8%)thought their infection was related to protective equipment,utilization of common equipment(masks and gloves).The top three first symptoms displayed before diagnosis were fever(41.8%),lethargy(33.0%)and muscle aches(30.1%).After diagnosis,88.3%staff experienced psychological stress or emotional changes during their isolation period,only 11.7%had almost no emotional ***(Umifenovir;an anti-influza drug;69.2%)was the drug most commonly used to target infection in mild and moderate ***:The main perceived mode of transmission was not maintaining protection when working at a close distance and having intimate contact with infected *** psychological intervention is necessa

关键词： COVID-19 SARS-CoV-2,2019-nCoV Healthcare worker Healthcare professional Infection transmission route Psychosocial status

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Overactive bladder

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Family Medicine and Community Health 2013年第4期1卷 36-39页

作者： Elizabeth Ferry Firouz Daneshgari Urology Institute University Hospitals Case Medical Center and Department of UrologyCase Western Reserve University School of MedicineClevelandOHUSA

Overactive bladder(OAB)is known to affect millions of people worldwide,with a subsequent deleterious impact on the quality of *** clinical diagnosis of OAB requires,at a minimum,a meticulous history,physical examination,and *** American Urological Association views OAB as a symptom complex,not a life-threatening disease,and recommends conservative measures and behavioral therapies as first-line treatment,including bladder training,bladder control strategies,pelvic floor muscle training,and fluid *** medical management approved by the US FDA include anti-muscarinics and ***-muscarincs should be avoided in patients with narrow-angle glaucoma,and used with extreme caution in patients with impaired gastric emptying or a history of urinary *** interventions may be offered,if second-line therapy using medications is not successful in obtaining adequate symptom control of OAB,and the patient is motivated and *** uncomplicated patients,OAB may be clinically diagnosed and treated with conservative measures;however,the armamentarium for the diagnosis and treatment continues to expand for more complicated patients.

关键词： Overactive bladder Definition Pathophysiology diagnosis Treatment

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changes in muscle activity in patients with primary chronic headache

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Life Research 2021年第2期4卷 50-56页

作者： Nigora Kadyrkhodjayeva Anna Prokhorova Saodat Ubaydullaeva Tashkent Medical Academy TashkentUzbekistan center for Sensory Integration and Speech Correction“TOMATIS” TashkentUzbekistan Private Clinic“Tibbiyot Dunyosi” TashkentUzbekistan

Objective:According to the Global Burden of disease Study,updated in 2018,headache disorders are the second leading cause in the world and impaired quality of life and lead to reduce daily activity and can be the cause of headache-related ***,we desperately need to develop new painless and minimally invasive methods to facilitate diagnosis to improve the quality of headache ***:Our study involved 92 participants over 18 years of age with a diagnosis of primary chronic *** those,36 were with chronic tension type headache,26 were with a chronic migraine,and 30 were healthy *** patients were selected according to the criteria of the International Headache *** questionnaires,instrumental data,and characteristics of headache episodes were collected from all *** evaluated the muscle activity of the pericranial and cervical muscles in patients with chronic headache to compare with healthy participants using Surface electromyography to determine if there is an alteration in muscle ***:Surface electromyography data showed that there was a statistically significant difference in results between the target group and the control group,where patients with primary chronic headache had high amplitude and velocity in the studied muscles on the *** the participants,there was a difference in the intensity of headache attacks on the visual analog scale chronic tension type headache 5.2±1.4,chronic migraine 7.7±1.3,control group 1.6±0.7 and in the frequency of headache attacks per month chronic tension type headache 14.4±1.9,chronic migraine 17.3±2.9,the control group of participants had headache attacks of≤1 per ***:We concluded that the patients with primary chronic headaches there are changes in the muscle activity of the pericranial and cervical *** contrast to patients without chronic headaches,which,in turn,the method of surface electromyography may encourage furt

关键词： Primary chronic headache Surface electromyography Pericranial muscles Cervical muscles visual analog scale

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