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China CDC weekly 2024年第4期6卷 61-63页

作者： Hongbing Shen Director-General of China CDC Academician of the Chinese Academy of EngineeringBeijingChina

The Chinese government has always attached great importance to disease control and prevention ***,the general office of China’s State Council issued the“Guidelines for High-Quality Development of Disease Prevention and Control”(hereinafter referred to as the“Guidelines”)(1).The Guidelines focus on promoting high-quality development of disease control and prevention and the strategic goal of“Healthy China,”providing specific implementation pathways for the development of national disease control and prevention in the new era,including overall planning,restructuring of governance,enhancing core capabilities,strengthening talent development,and improving organizational support.

关键词： prevention attached Quality

Extensive reforms to improve funding efficiency:an interview with President Xiankang Dou of National Natural Science Foundation of China

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National Science Review 2024年第6期11卷 321-324页

作者：赵维杰朱禾 the editorial office of NSR in Beijing

Dr. Xiankang Dou (窦贤康) was appointed the President of the National Natural Science Foundation of China (NSFC) in April 2023. As a distinguished researcher specializing in studying the middle and upper atmosphere of earth, Dr. Dou had served as the President of Wuhan University during 2016 to 2022 and was elected an academician of the Chinese Academy of Sciences (CAS) in 2017.

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Long-term functional outcomes improved with deep brain stimulation in patients with disorders of consciousness

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Stroke & Vascular Neurology 2023年第5期8卷 368-378页

作者： Yi Yang Qiheng He Yuanyuan Dang Xiaoyu Xia Xin Xu Xueling Chen Jizong Zhao Jianghong He Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Translational Medicine Center Chinese Institute for Brain ResearchBeijingChina Beijing Institute of Brain Disorders Capital Medical UniversityBeijingChina Department of Neurosurgery PLA General HospitalBeijingChina academician office China National Clinical Research Center for Neurological DiseasesBeijingChina

Background Deep brain stimulation(DBS)has been preliminarily applied to treat patients with disorders of consciousness(DoCs).The study aimed to determine whether DBS was effective for treating patients with DoC and identify factors related to patients’*** Data from 365 patients with DoCs who were consecutively admitted from 15 July 2011 to 31 December 2021 were retrospectively *** regression and subgroup analysis were performed to adjust for potential *** primary outcome was improvement in consciousness at 1 *** An overall improvement in consciousness at 1 year was achieved in 32.4%(12/37)of the DBS group compared with 4.3%(14/328)of the conservative *** full adjustment,DBS significantly improved consciousness at 1 year(adjusted OR 11.90,95%CI 3.65-38.46,p<0.001).There was a significant treatment×follow up interaction(H=14.99,p<0.001).DBS had significantly better effects in patients with minimally conscious state(MCS)compared with patients with vegetative state/unresponsive wakefulness syndrome(p for interaction<0.001).A nomogram based on age,state of consciousness,pathogeny and duration of DoCs indicated excellent predictive performance(c-index=0.882).Conclusions DBS was associated with better outcomes in patients with DoC,and the effect was likely to be significantly greater in patients with *** should be cautiously evaluated by nomogram preoperatively,and randomised controlled trials are still needed.

关键词： stimulation patients admitted

Characterization of the Crustal Thickness and Poisson's Ratio of the Binchuan Region

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Earthquake Research in China 2017年第1期31卷 79-89页

作者： Deng Jiamei Jin Mingpei Chen Jia Gao Qiong Zhang Huaying Wang Jun Ye Beng office of the Western Yunnan Earthquake Prediction Study Area CEA

This paper presents the changes of crust thickness and Poisson＇s ratios distribution in the Binchuan region, where the first air-gun transmitting station and it＇s a small dense array were deployed. From September 2011 to January 2014, more than 239 teleseismic events of M≥ 6.0 were recorded in 16 stations in the Binchuan region. Their P-wave receiver functions were analyzed respectively. The high spatial resolution result shows that the average crust thickness of Binchuan region is 45.3km, it follows the rule of ＂deeper in the north and east part, shallower in the south and west part. ＂ The deepest region is in Xiaoyindian Station; the crust thickness is 47.9km; the shallowest region is in Paiying Station, it has the thickness of 42. lkm. It shows that the deeper Moho surface nearby the Chenghai fault and shallower nearby the Honghe fault; the isoline distribution of thickness changes greatly nearby the Chenghai fault and slowly nearby the Honghe fault. From the distribution of Poisson＇s ratios, it is unevenly in the study area with a great difference from the north part to the south part, which shows a characteristic of ＂lower in the north, higher in the south＂. The Poisson＇s ratio nearby the Honghe fault is medium too high （ 0. 26 ≤ σ≤0. 29 ） ; lower nearby the Chenghai fault （ ≤0. 26）. This paper concludes the possible reason of different characteristic between Poisson＇s ratio and crust thickness is thicker in the upper crust in the Binchuan region.

关键词： Crustal thickness Poisson's ratio Receiver function The Binchuan region

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VIS Atlas:A Database of Virus Integration Sites in Human Genome from NGS Data to Explore Integration Patterns

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Genomics, Proteomics & Bioinformatics 2023年第2期21卷 300-310页

作者： Ye Chen Yuyan Wang Ping Zhou Hao Huang Rui Li Zhen Zeng Zifeng Cui Rui Tian Zhuang Jin Jiashuo Liu Zhaoyue Huang Lifang Li Zheying Huang Xun Tian Meiying Yu Zheng Hu Department of Obstetrics and Gynecology the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510000China Department of Obstetrics and Gynecology Dongguan Maternal and Child Health Care HospitalDongguan 523000China office of Scientific Research&Development Sun Yat-sen UniversityGuangzhou 510000China Department of Obstetrics and Gynecology Academician Expert WorkstationThe Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Center for Translational Medicine the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510000China Department of Pathology the Central Hospital of Enshi Tujia and Miao Autonomous PrefectureEnshi 445000China Department of Obstetrics and Gynecology Zhongnan Hospital of Wuhan UniversityWuhan 430062China

Integration of oncogenic DNA viruses into the human genome is a key step in most virusinduced ***,we constructed a virus integration site(VIS)Atlas database,an extensive collection of integration breakpoints for three most prevalent oncoviruses,human papillomavirus,hepatitis B virus,and Epstein-Barr virus based on the next-generation sequencing(NGS)data,literature,and experimental *** are 63,179 breakpoints and 47,411 junctional sequences with full annotations deposited in the VIS Atlas database,comprising 47 virus genotypes and 17 disease *** VIS Atlas database provides(1)a genome browser for NGS breakpoint quality check,visualization of VISs,and the local genomic context;(2)a novel platform to discover integration patterns;and(3)a statistics interface for a comprehensive investigation of genotypespecific integration *** collected in the VIS Atlas aid to provide insights into virus pathogenic mechanisms and the development of novel antitumor drugs.

关键词： DNA virus Virus integration site Next-generation sequencing Integration pattern Virus genotype

Bio-manufacturing innovation lights up the future Report from the Second Bio-Design & Manufacturing Youth Forum

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Bio-Design and Manufacturing 2023年第2期6卷 204-215页

作者： Liang Ma Huayong Yang State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou 310058China School of Mechanical Engineering Zhejiang UniversityHangzhou 310058China The Editorial office of Bio-Design and Manufacturing Zhejiang UniversityHangzhou 310058China

Bio-manufacturing,a frontier interdisciplinary subject,is a promising field full of creative thinking and innovation[1].In order to create a platform for young scientists and students in the bio-manufacturing field to have a good chance of communication and discussion,based on the success of First Bio-Design&Manufacturing Youth Forum in 2021[2],the Second Bio-Design&Manufacturing Youth Forum chaired by the editor-in-chief academician Huayong Yang and jointly sponsored by the journal of Bio-Design and Manufacturing,School of Mechanical Engineering,Zhejiang University and the State Key Laboratory of Fluid Power and Mechatronic Systems was successfully held in Hangzhou on November 19,*** prestigious young scientists were invited to deliver a speech on their own research both onsite and online。

关键词： academician lights jointly

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Celebrating the 40th Anniversary of China's Breakthrough in Coal-derived Gas Research

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Petroleum Exploration and Development 2019年第3期 434-434页

作者： Editorial office of Petroleum Exploration and Development Editorial office of Petroleum Exploration and Development

The publication of the article"Petroleum and natural gas generation during coalification"by academician Dai Jinxing in the 3rdissue of the Petroleum Exploration and Development in 1979 has marked the beginning of China's journey of theoretical research of coal-derived gas and its exploration and *** has been a journey of 40 years'glory and *** research on coal-derived gas broke the traditional understanding that coal-measure is the forbidden zone for natural gas *** provided important scientific guidance for opening up new fields in natural gas exploration,and for realizing the forward-leaping development in China's natural gas *** also enhanced significant development in natural gas industry in China and helped to make extraordinary achievements that attracted world ***,we would like

关键词： China Anniversary of China’s Breakthrough in Coal-derived Gas Research Celebrating the 40

“Banlangen (Radix isatidis) compound granules as a treatment for COVID-19”-the market value of Baiyunshan pharmaceutical soared by 10 billion RMB

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Traditional Medicine Research 2021年第1期6卷 1-2页

作者： Dan Chen Editorial office TMR Publication Group LimitedAuckland 2014New Zealand

On October 13,2020,the fourth board meeting of the Guangdong-Macao Joint Research Centre for New Drug Discovery against respiratory pathogens and the Macao Symposium on Translation of Baiyunshan Banlangen and Cooperation Agreement Signing Ceremony was held in *** the meeting,Zhong Nanshan,a recipient of Medal of the Republic and an academician in the Chinese Academy of Engineering,revealed that a series of in vitro studies performed by his research team had found Baiyunshan Compound Banlangen granules to be effective in treating COVID-19[1].Driven by this message,the Aand H-share prices of Baiyunshan pharmaceutical increased to a large scale,with the former hitting the daily limit-up price at mid-session and the latter exceeding 13%of increases at one point during the session.

关键词： exceeding treatment latter

Xiao-Ping Chen:the“Master of the Scalpel”who saves lives by entering the forbidden territory of hepatopancreatobiliary surgery

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Oncology and Translational Medicine 2023年第6期9卷 239-240页

作者： Editorial office of Oncology and Translational Medicine Editorial office Tongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhanHubeiChina

In his 50 years of practice,he has performed more than 20,000 hepatopancreatobiliary surgeries,being the first one to propose the concept of the“auxiliary partial orthotopic liver transplantation”***,he developed the“Chen's inserting biliary-enteric anastomosis and pancreato-enteric anastomosis,”“Chen's hepatic vascular occlusion,”“Chen's liver double-hanging maneuver,”and“Chen's hepatic vascular occlusion without liver portal dissection.”He also popularized these theories and techniques both in China and *** name is Xiao-Ping Chen,an academician of the Chinese Academy of Sciences and honorary president of the Tongji Medical College of Huazhong University of Science and Technology.

关键词： hepato biliary lives

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Work Conference of Chinese Herbal Medicines was Held in Beijing

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Chinese Herbal Medicines 2013年第3期 160-160页

作者： Editorial office of Chinese Herbal Medicines Editorial office of Chinese Herbal Medicines

In order to further prompt the rapid development of CHM toward the direction of internationalization,the temporary work conference of Chinese Herbal Medicines(CHM)editorial office was held in Beijing Rainbow Hotel on March 6,*** participants included *** Pei-gen(academician of CAE,editor-in-chief of CHM),*** Chang-xiao(academician of CAE),*** Li-da(President of TIPR),*** Shi-lin(associate editors-in-chief),senior staff of Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Development which are secretary units of CHM,

关键词： Work Conference of Chinese Herbal Medicines was Held in Beijing