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时代数学学习(八年级) 2005年第5期 33-36页

作者：周奕生福建省安溪15中

Immunomodulation as a neuroprotective strategy after spinal cord injury

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Neural Regeneration Research 2018年第3期13卷 423-424页

作者： Susana Monteiro António J. Salgado Nuno A. Silva Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoCampus de GualtarBragaPortugal ICVS/3B's-PT Government Associate Laboratory Braga/GuimaraesPortugal

The initial trauma to the spinal cord is just the starting point for a cascade of endogenous events that will collectively determine the injury extension. These secondary events include, but are not limited to： glutamate excitoxicity, induction of apoptotic pathways, ionic imbalances and the development of a strong and dysfunctional inflammatory response. The secondary injury is associated to an aggravation of neuronal damage increasing the extent of neurological deficits （Ek et al., 2010）.

关键词： Immunomodulation as a neuroprotective strategy after spinal cord injury SCI

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SMW工法在城市快速通道建设中的应用

地下工程与隧道 2007年第2期 23-24,28页

作者：贾贯乾中铁15局集团公司

结合南京某工程,介绍了SMW工法在施工中应引起注意的几个问题,阐述该工法造价低、工期短、材料循环利用、环境影响小等方面的特点,提出结合工程实际,适当加大SMW工法桩桩长的观点。

关键词： SMW工法城市快速通道基坑围护应用推广

Integration of VR with BIM to facilitate real-time creation of bill of quantities during the design phase: A proof of concept study

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Frontiers of Engineering Management 2020年第3期7卷 396-403页

作者： Jordan DAVIDSON John FOWLER Charalampos PANTAZIS Massimo SANNINO Jordan WALKER Moslem SHEIKHKHOSHKAR Farzad Pour RAHIMIAN Department of Architecture University of StrathclydeGlasgowG11XJUK Department of Mechanical and Construction Engineering Faculty of Engineering and EnvironmentNorthumbria UniversityNewcastle NE18STUK

As building practices change,procedures that seemed indispensable at one point can be abandoned for others,one example of which is the bill of quantities(B/Q).Research into the extant literature attributes the declining use of B/Qs to a multitude of reasons,such as its complexity,the potentially long time required to produce it,the growth in popularity of non-traditional procurement systems,and the challenge of using the information within the document in a construction *** these issues in mind,building information modeling(BIM)and virtual reality(VR)are combined and proposed as a potential solution that allows inclusion of the client into the design *** a literature review and precedent study,an experiment was carried out using this new process to simulate a client’s design decisions on window and interior *** choices made by the client using VR automatically updated a B/Q schedule built in Revit and allowed them to have a firm understanding of project *** giving the client more confidence in a pleasing final outcome,the technology also ensured an up-to-date,accurate,and easily understandable B/*** proposed method features great potential savings in cost and time and gives the B/Q a newfound importance in future construction *** research case presented in this paper is a stepping stone in exploring new opportunities offered by VR and BIM and how they could improve the reliability and accuracy of traditional procurement within construction,specifically within the B/Q document.

关键词： virtual reality bill of quantities BIM Revit real-time synchronisation

Identifying genetic susceptibility to Aspergillus fumigatus infection using collaborative cross mice and RNA-Seq approach

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Animal Models and Experimental Medicine 2024年第1期7卷 36-47页

作者： Roa'a H.S.Yosief Iqbal M.Lone Aharon Nachshon Heinz Himmelbauer Irit Gat-Viks Fuad A.Iraqi Department of Clinical Microbiology and Immunology Sackler Faculty of MedicineTel-Aviv UniversityTel-AvivIsrael School of Molecular Cell Biology and Biotechnology George S.Wise Faculty of Life SciencesTel Aviv UniversityTel AvivIsrael Institute of Computational Biology Department of BiotechnologyUniversity of Natural Resources and Life SciencesMuthgasse 181190 ViennaAustria

Background:Aspergillus fumigatus(Af)is one of the most ubiquitous fungi and its infection potency is suggested to be strongly controlled by the host genetic *** aim of this study was to search for candidate genes associated with host susceptibility to Aspergillus fumigatus(Af)using an RNAseq approach in CC lines and hepatic gene ***:We studied 31 male mice from 25 CC lines at 8 weeks old;the mice were infected with *** tissues were extracted from these mice 5 days post-infection,and next-generation RNA-sequencing(RNAseq)was *** GENE-E analysis platform was used to generate a clustered heat map ***:Significant variation in body weight changes between CC lines was *** gene expression revealed 12 top prioritized candidate genes differ-entially expressed in resistant versus susceptible mice based on body weight ***,three candidate genes are located within genomic intervals of the previ-ously mapped quantitative trait loci(QTL),including Gm16270 and Stox1 on chromo-some 10 and Gm11033 on chromosome ***:Our findings emphasize the CC mouse model's power in fine mapping the genetic components underlying susceptibility towards *** a next step,eQTL analysis will be performed for our RNA-Seq *** candidate genes from our study will be further assessed with a human cohort with aspergillosis.

关键词： aspergillus fumigatus infection collaborative cross(CC)mice gene expression profile gene-network host susceptibility quantitative trait loci(QTL)mapping RNA-Seq

Polyoxometalates-engineered hydrogen generation rate and durability of Pt/CNT catalysts from ammonia borane

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Journal of Energy Chemistry 2020年第2期29卷 142-148页

作者： Wenzhao Fu Chen Han Dali Li Wenyao Chen Jian Ji Gang Qian Weikang Yuan Xuezhi Duan Xinggui Zhou State Key Laboratory of Chemical Engineering East China University of Science and TechnologyShanghai 200237China Department of Chemical Engineering and Applied Chemistry University of TorontoToronto.Ontario M5S 3E5Canada

Heterogeneously catalyzed hydrolytic dehydrogenation of ammonia borane is a remarkable structure sensitive reaction. In this work, a strategy by using polyoxometalates(POMs) as the ligands is proposed to engineer the surface and electronic properties of Pt/CNT catalysts toward the enhanced hydrogen generation rate and durability. Three kinds of POMs, i.e., silicotungstic acid(STA), phosphotungstic acid(PTA)and molybdophosphoric acid(PMA), are comparatively studied, among which the STA shows positive effects on the catalytic activity and durability. A catalyst structure-performance relationship is established by a combination of kinetic and isotopic analyses with multiple characterization techniques, such as HAADF-STEM, EDS, Raman spectroscopy and XPS. It is shown that the STA compared to the other two POMs can increase the Pt binding energy and thus promote the reaction. The insights demonstrated here could open a new avenue for boosting the reaction by employing the POMs as the ligands to engineer the catalyst electronic properties.

关键词： Polyoxometalates Pt/CNT Electronic properties Hydrogen generation Durability

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科学的办学思路高标准的培养目标

宣武教育 2001年第4期 1-2页

作者：吴秉寅北京15中分校校长

ACTIVE VIBRATION SUPPRESSION VIA LINEARIZING HYSTERESIS OF PIEZOCERAMIC ACTUATORS

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Chinese Journal of Mechanical Engineering 2007年第4期20卷 84-87页

作者： HU Hong SHI Hongyan BEN MRAD Ridha Department of Mechanical Engineering and Automation Harbin Institute of Technology Shenzhen Graduate School Shenzhen 518055. China Department of Mechanical and Industrial Engineering University of Toronto Toronto MSS 3G8. Canada

A novel active vibration control technique on the basis of linearized piezoelectric actuators is presented. An experimental apparatus consisting of a cantilever beam to which are attached strain patches and piezoceramic actuators to be used for active vibration suppression is described. A dynamical model of the cantilever beam using Lagrange＇s equation and two coordinate systems are presented. Based on the Lyapunov＇s direct method, an active vibration controller with hysteresis compensation is designed. The controller is designed so that it guarantees the global stability of the overall system. The controller developed is assessed experimentally.

关键词： Active vibration control Piezoceramic actuator Hysteresis

The importance of glutathione and phytochelatins on the selenite and arsenate detoxification in Arabidopsis thaliana

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Journal of Environmental Sciences 2016年第11期28卷 150-161页

作者： Fatai Adigun Aborode Andrea Raab Matthias Voigt Leticia Malta Costa Eva M.Krupp Joerg Feldmann Trace Element Spedation Laboratory Department of Chemistry University of Aberdeen Aberdeen AB24 3UE Scotland UK Departamento de Quimica Uniuersidade Federal de Minas Gerais Belo Horizonte MG CEP： 31270-901 Brazil

We investigated the role of glutathione（GSH） and phytochelatins（PCs） on the detoxification of selenite using Arabidopsis thaliana. The wild-type（WT） of Arabidopsis thaliana and its mutants（glutathione deficient Cad 2–1 and phytochelatins deficient Cad 1–3） were separately exposed to varying concentrations of selenite and arsenate and jointly to both toxicants to determine their sensitivities. The results of the study revealed that, the mutants were about 20-fold more sensitive to arsenate than the WT, an indication that the GSH and PCs affect arsenate detoxification. On the contrary, the WT and both mutants showed a similar level of sensitivity to selenite, an indication that the GSH and PCs do not significantly affect selenite detoxification. However, the WT is about 8 times more sensitive to selenite than to arsenate, and the mutants were more resistant to selenite than arsenate by a factor of 2. This could not be explained by the accumulation of both elements in roots and shoots in exposure experiments. The co-exposure of the WT indicates a synergistic effect with regards to toxicity since selenite did not induce PCs but arsenic and selenium compete in their PC binding as revealed by speciation analysis of the root extracts using HPLC–ICP–MS/ESI–MS. In the absence of PCs an antagonistic effect has been detected which might suggest indirectly that the formation of Se glutathione complex prevent the formation of detrimental selenopeptides. This study, therefore, revealed that PC and GSH have only a subordinate role in the detoxification of selenite.

关键词： Toxicity Phytochelatins Glutathione Selenopeptides ICP–MS ESI–MS Arabidopsis thaliana