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Safety Guide-Line and Requirements for Distributed Raman Amplification and its Applications to WDM Transmission Systems

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光学学报 2003年第S1期23卷 556-557页

作者： Masahito Tomizawa Akira Hirano Yutaka Miyamoto NTT Network Innovation Laboratories NTT Corporation 1-1 Hikari-no-oka Yokosuka 239-0847 JapanNTT Network Innovation Laboratories NTT Corporation 1-1 Hikari-no-oka Yokosuka 239-0847 JapanNTT Network Innovation Laboratories NTT Corporation 1-1 Hikari-no-oka Yokosuka 239-0847 Japan

This paper discusses optical safety issues in distributed Raman amplification systems. Given the extremely high pump powers, network service operators have critical issues for safety. This paper focuses on both " eye-... 详细信息

关键词： for it on high In be of Safety Guide-Line and Requirements for Distributed Raman Amplification and its Applications to WDM Transmission Systems APR into

Low-Driving-Voltage Optical Modulation Utilizing FWM for High-Speed Transmission Systems

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光学学报 2003年第S1期23卷 562-563页

作者： Akihiko Matsuura Toshiya Matsuda Tomoyoshi Kataoka NTT Network Service Systems Laboratories 1-1 Hikarinooka Yokosuka-Shi Kanagawa 239-0847 JapanNTT Network Service Systems Laboratories 1-1 Hikarinooka Yokosuka-Shi Kanagawa 239-0847 JapanNTT Network Service Systems Laboratories 1-1 Hikarinooka Yokosuka-Shi Kanagawa 239-0847 Japan

We propose an optical transmitter with reduced modulator driving voltage. This reduction is achieved through an on-off ratio improvement technique based on FWM. We confirmed the feasibility of the method in a 43-Gbit/... 详细信息

关键词： FWM on in for Low-Driving-Voltage Optical Modulation Utilizing FWM for High-Speed Transmission Systems

Supercontinuum Lightwave Sources for Photonic Networks

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光学学报 2003年第S1期23卷 733-734页

作者： Kunihiko Mori NTT Network Innovation Laboratories NTT Corporation 1-1 Hikari-no-oka Yokosuka Kanagawa 239-0847 Japan

WDM optical sources based on supercontinuum (SC) generation are reviewed. The design of an SC lightwave source is described that uses a scaling rule among the parameters in an SC generating fiber and a seed optical pu... 详细信息

关键词： for in et on SC Supercontinuum Lightwave Sources for Photonic Networks WDM

Use of groundwater flow model in the analysis of a creeping landslide in western japan

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Episodes 2006年第1期29卷 20-25页

作者： H.K. Shrestha R. Yatabe N.P. Bhandary Graduate School of Science and Engineering Ehime University Japan. Faculty of Engineering Ehime University Japan.

To predict the movement of an existing creeping landslide, monitoring and analysis of hydrological parameters are crucial This paper analyses the hydrological parameters of an existing creeping landslide site in western japan. The groundwater flow and resulting fluctuation in pore water pressure at the slip layer of a sliding block was simulated using a groundwater flow model. A quasithree-dimensional factor of safety of the block was obtained by combining the groundwater model with slope stability analysis methods. The results show that for prediction purposes at a creeping landslide site the time series analysis using longterm data is of limited use, because the fluctuations of ground surface movement and hydrological parameters are not completely synchronized when the factor of safety of the slope soil is in the creep movement range. The ground surface movement rate dropped after each episode of relatively big movement, even when the hydrological parameters were constant. The factor of safety of the sliding block was more influenced by groundwater recharge from the hills than by rainfall. Pore water pressure fluctuation obtained from groundwater flow model resulting from specific rainfall events indicated better relations between fluctuations in pore water pressure and ground surface movement.

关键词：日本滑坡地下水流动模型动力地质

P2Y1 receptor in Alzheimer’s disease

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维普期刊数据库

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Neural Regeneration Research 2025年第2期20卷 440-453页

作者： Shan Luo Yifei Wang Tatsuhiro Hisatsune Department of Integrated Biosciences The University of TokyoKashiwaJapan

Alzheimer’s disease is the most frequent form of dementia characterized by the deposition of amyloid-beta plaques and neurofibrillary tangles consisting of hyperphosphorylated *** amyloid-beta plaques has been a primary direction for developing Alzheimer’s disease treatments in the last ***,existing drugs targeting amyloid-beta plaques have not fully yielded the expected results in the clinic,necessitating the exploration of alternative therapeutic *** evidence unravels that astrocyte morphology and function alter in the brain of Alzheimer’s disease patients,with dysregulated astrocytic purinergic receptors,particularly the P2Y1 receptor,all of which constitute the pathophysiology of Alzheimer’s *** receptors are not only crucial for maintaining normal astrocyte function but are also highly implicated in neuroinflammation in Alzheimer’s *** review delves into recent insights into the association between P2Y1 receptor and Alzheimer’s disease to underscore the potential neuroprotective role of P2Y1 receptor in Alzheimer’s disease by mitigating neuroinflammation,thus offering promising avenues for developing drugs for Alzheimer’s disease and potentially contributing to the development of more effective treatments.

关键词： astrocytes neuroinflammation P2Y1 receptor purinergic receptor

Disruption of neuronal actin barrier promotes the entry of disease-implicated proteins to exacerbate amyotrophic lateral sclerosis pathology

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Neural Regeneration Research 2025年第9期20卷 2589-2590页

作者： Mikio Shimizu Tatsusada Okuno Department of Neurology Osaka University Graduate School of MedicineSuitaJapan Department of Neurology Osaka General Medical CenterOsakaJapan

Amyotrophic lateral sclerosis(ALS)is a devastating neurological disease characterized by the accumulation of aberrant proteins in motor neurons of the brain and spinal *** with ALS develop skeletal muscle weakness,resulting in death from respiratory paralysis,which usually occurs 2-4 years after clinical onset(Goutman et al.,2022).

关键词： paralysis sclerosis

Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration

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Neural Regeneration Research 2025年第3期20卷 797-798页

作者： Takayuki Nakagomi Institute for Advanced Medical Sciences Hyogo Medical UniversityNishinomiyaJapan Department of Therapeutic Progress in Brain Diseases Hyogo Medical UniversityNishinomiyaJapan

Brain injuries like ischemic stroke induce endogenous stem cell production. Although the precise traits of stem cells in pathological brains remain unclear, we previously demonstrated that injury/ischemia-induced stem... 详细信息

关键词： ischemia injuries

Therapeutic potential of stem cells in subarachnoid hemorrhage

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Neural Regeneration Research 2025年第4期20卷 936-945页

作者： Hideki Kanamaru Hidenori Suzuki Department of Neurosurgery Mie University Graduate School of MedicineTsuJapan

Aneurysm rupture can result in subarachnoid hemorrhage,a condition with potentially severe consequences,such as disability and *** the acute stage,early brain injury manifests as intracranial pressure elevation,global cerebral ischemia,acute hydrocephalus,and direct blood–brain contact due to aneurysm *** may subsequently cause delayed cerebral infarction,often with cerebral vasospasm,significantly affecting patient *** complications such as brain volume loss and chronic hydrocephalus can further impact *** the mechanisms of subarachnoid hemorrhage-induced brain injury is paramount for identifying effective *** cell therapy,with its multipotent differentiation capacity and anti-inflammatory effects,has emerged as a promising approach for treating previously deemed incurable *** review focuses on the potential application of stem cells in subarachnoid hemorrhage pathology and explores their role in neurogenesis and as a therapeutic intervention in preclinical and clinical subarachnoid hemorrhage studies.

关键词： delayed cerebral ischemia early brain injury matricellular protein neurogenesis stem cell therapy subarachnoid hemorrhage

Analysis of XGM-Based Wavelength-Conversion in SOAs Using Assist Light

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光学学报 2003年第S1期23卷 345-346页

作者： Kenichiro Tsuji Noriaki Onodera Masatoshi Saruwatari Department of Communications Engineering National Defense Academy 1-10-20 Hashirimizu Yokosuka 239-8686 Japan.Department of Communications Engineering National Defense Academy 1-10-20 Hashirimizu Yokosuka 239-8686 Japan.Department of Communications Engineering National Defense Academy 1-10-20 Hashirimizu Yokosuka 239-8686 Japan.

Wavelength conversion based on the cross-gain modulation (XGM) in a traveling-wave type semiconductor optical amplifier (TW-SOA) using assist light is theoretically studied. Taking into account the spatial and temporal variations of carrier density along the SOA length, the dependency of the conversion response on the assist light conditions is simulated both for co- and counter-propagating assist light schemes.

关键词： of as length SOA on dBm Analysis of XGM-Based Wavelength-Conversion in SOAs Using Assist Light in