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Does MgSO_(4) protect the preterm brain?Dissecting its role in the pathophysiology of hypoxic ischemic encephalopathy

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Neural Regeneration Research 2024年第9期19卷 1861-1862页

作者： Robert Galinsky Laura Bennet Alistair J.Gunn The Ritchie centre Hudson Institute of Medical ResearchMelbourneVICAustralia Department of Obstetrics and Gynaecology Monash UniversityMelbourneVICAustralia Department of Physiology The University of AucklandAucklandNew Zealand

Mitigating preterm encephalopathy continues to be one of the greatest challenges in perinatal *** encephalopathy is associated with high mortality,serious morbidity,and significant socio-economic impacts on the individuals,their families,and public health sectors and welfare systems that last a *** cost of disability associated with preterm brain injury continues to *** of this injury,and disability,would significantly reduce this socioeconomic burden.

关键词： encephalopathy mortality hypoxic

世行与IMF为何对东亚金融危机有分歧?——综观经济学之启示

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经济研究 1999年第1期34卷 18-21页

作者：黄有光澳洲monash大学

东亚金融风暴有着持续与广泛的影响，而关于应如何解决危机的问题，经济学者与有关机构和决策者间也有很多不同意见。尤其令人瞩目的是两大国际机构，世界银行与国际货币基金组织（ＩＭＦ）在这个问题上的相反建议。ＩＭＦ给贷款国的条... 详细信息

东亚金融风暴有着持续与广泛的影响，而关于应如何解决危机的问题，经济学者与有关机构和决策者间也有很多不同意见。尤其令人瞩目的是两大国际机构，世界银行与国际货币基金组织（ＩＭＦ）在这个问题上的相反建议。ＩＭＦ给贷款国的条件，包括紧缩的货币与财政政策，取消...

关键词：世界 IMF 东亚地区金融危机综观经济学

An Efficient Method to Estimate Admittance of Black-boxed Inverter-based Resources for Varying Operating Points

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 421-426页

作者： Weihua Zhou Bin Liu Nabil Mohammed Behrooz Bahrani Department of Electrical and Computer Systems Engineering Monash UniversityMelbourne 3800Australia Energy centre Commonwealth Scientific and Industrial Research Organisation(CSIRO)Newcastle 2300Australia.He is now with the Network Planning DivisionTransgridSydney 2000Australia

Traditional analytical approaches for stability assessment of inverter-based resources(IBRs),often requiring detailed knowledge of IBR internals,become impractical due to IBRs’proprietary *** measurements,relying on electromagnetic transient simulation or laboratory settings,are not only time-intensive but also operationally inflexible,since various non-linear control loops make IBRs’admittance models operating-point ***,such admittance measurements must be performed repeatedly when operating point *** avoid time-consuming and cumbersome measurements,admittance estimation for arbitrary operating points is highly ***,existing admittance estimation algorithms usually face challenges in versatility,data demands,and *** this challenge,this letter presents a simple and efficient admittance estimation method for blackboxed IBRs,by utilizing a minimal set of seven operating points to solve a homogeneous linear equation *** studies demonstrate this proposed method ensures high accuracy across various types of *** accuracy is satisfying even when non-negligible measurement errors exist.

关键词： Admittance estimation black box inverterbased resource measurement error operating point

将WHO《心理健康差距干预指南》应用于中国全科医学服务:一项德尔菲研究

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中国全科医学 2024年第1期27卷 15-26页

作者： Kendall Searle Grant Blashki Ritsuko Kakuma 杨辉吕淑荣李宝琪肖莹莹 Harry Minas VIC 3010 Global and Cultural Mental Health Unit Centre for Mental HealthSchool of Population and Global HealthUniversity of MelbourneParkvilleAustralia VIC 3010 Nossal Institute for Global Health University of MelbourneMelbourneAustralia WC1E 7HTE London School of Hygiene and Tropical Medicine LondonEnglandUK VIC 3168 monash Institute for Health and Clinical Education School of Primary Health CareMonash UniversityNotting HillAustralia 中国科学院大学深圳医院(光明) 广东省深圳市518107

背景中国全科医生越来越期望能够识别和预防抑郁障碍,但其接受的心理健康培训有限,社区卫生服务中心(CHCs)也缺乏针对抑郁障碍的诊断和服务规范。WHO《心理健康差距干预指南》第2版(mhGAP-IG.v2)是为非心理健康专业人员提供的决策支持工... 详细信息

背景中国全科医生越来越期望能够识别和预防抑郁障碍,但其接受的心理健康培训有限,社区卫生服务中心(CHCs)也缺乏针对抑郁障碍的诊断和服务规范。WHO《心理健康差距干预指南》第2版(mhGAP-IG.v2)是为非心理健康专业人员提供的决策支持工具,可用于评估、管理、随访精神障碍、神经疾病及物质使用障碍患者。鉴于mhGAP-IG.v2的通用性,其在中国的应用应根据抑郁障碍在不同文化下的差异性和中国心理健康系统特点进行调整。方法开展两轮基于网络的德尔菲(Delphi)调查。邀请来自深圳市的全科医生小组对mhGAP-IG.v2中涉及抑郁障碍的199条表述进行五分制的赞同程度打分,即“如要把该表述用在深圳市,是否赞同调整其内容和结构”。如果>80%的全科医生“有些/肯定赞同”调整某表述,则视为全科医生对调整该表述达成共识;如果>80%的全科医生“有些/肯定不赞同”调整某表述,则视为全科医生对不调整该表述达成共识。结果全科医生对79%的表述达成了需要调整的共识,平均得分为4.26分,即全科医生“有些赞同”对mh GAP-IG.v2中涉及抑郁障碍的相关表述进行调整。具体调整建议包括:抑郁评估方法应考虑更广泛的抑郁症状,并考虑病情的发展阶段;增加抑郁筛查工具的使用指南;明确全科医生的作用,以及家庭参与和跨部门服务的转诊途径;药物治疗建议应与中国用药规范保持一致;指南所有章节要强调预防自杀;情境化健康教育;强调“以人为本”的服务方法。全科医生认为,应维持mhGAP-IG.v2中对经历抑郁发作的双相障碍患者的诊断和治疗建议。结论对mhGAP-IG.v2抑郁部分的调整研究反映出对指南的评估应考虑文化和国情背景,包括中国特色的初级卫生保健系统、健康优先领域、治疗可得性,以及多样化的社会心理教育需要。调整后的mhGAP-IG.v2可以给中国全科医学教育和全科医疗服务提供参考,也可以为其他国家的非精神病学专业人员开展心理健康服务提供有益借鉴。

关键词：抑郁障碍心理健康差距干预指南德尔菲调整概念化初级保健跨部门服务世界卫生组织中国深圳

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谈效用、福利与快乐——关于“三人对谈录”的一点感想

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浙江社会科学 2003年第2期 39-41页

作者：黄有光澳洲monash大学经济系

叶航、汪丁丁、罗卫东的三人谈,涉及许多专门问题,我只针对效用与快乐的问题,谈我个人的看法.

关键词：效用福利福利经济学个人偏好经济学

Proteomics techniques in protein biomarker discovery

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Quantitative Biology 2024年第1期12卷 53-69页

作者： Mahsa Babaei Soheila Kashanian Huang-Teck Lee Frances Harding Department of Biology Faculty of ScienceRazi UniversityKermanshahIran Faculty of Chemistry Sensor and Biosensor Research Center(SBRC)Razi UniversityKermanshahIran Nanobiotechnology Department Faculty of Innovative Science and TechnologyRazi UniversityKermanshahIran centre for Marine Bioproducts Development Flinders UniversityAdelaideSouth AustraliaAustralia monash Institute of Pharmaceutical Sciences Monash UniversityMelbourneNew South WalesAustralia

Protein biomarkers represent specific biological activities and processes, so they have had a critical role in cancer diagnosis and medical care for more than 50 years. With the recent improvement in proteomics technologies, thousands of protein biomarker candidates have been developed for diverse disease states. Studies have used different types of samples for proteomics diagnosis. Samples were pretreated with appropriate techniques to increase the selectivity and sensitivity of the downstream analysis and purified to remove the contaminants. The purified samples were analyzed by several principal proteomics techniques to identify the specific protein. In this study, recent improvements in protein biomarker discovery, verification, and validation are investigated. Furthermore, the advantages, and disadvantages of conventional techniques, are discussed. Studies have used mass spectroscopy (MS) as a critical technique in the identification and quantification of candidate biomarkers. Nevertheless, after protein biomarker discovery, verification and validation have been required to reduce the false-positive rate where there have been higher number of samples. Multiple reaction monitoring (MRM), parallel reaction monitoring (PRM), and selected reaction monitoring (SRM), in combination with stable isotope-labeled internal standards, have been examined as options for biomarker verification, and enzyme-linked immunosorbent assay (ELISA) for validation.

关键词： biomarker discovery cancer biomarker gel-based methods gel-free methods mass spectroscopy proteomics

Graphene-calcium carbonate coating to improve the degradation resistance and mechanical integrity of a biodegradable implant

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Journal of Magnesium and Alloys 2024年第1期12卷 394-404页

作者： Lokesh Choudhary Parama Chakraborty Banerjee R.K.Singh Raman Derrek E.Lobo Christopher D.Easton Mainak Majumder Frank Witte Jörg F.Löffler Department of Mechanical and Aerospace Engineering Monash UniversityClayton CampusMelbourneVIC 3800Australia Department of Chemical and Biological Engineering Monash UniversityClayton CampusMelbourneVIC 3800Australia Nanoscale Science and Engineering Laboratory(NSEL) Bldg 37Monash UniversityClayton CampusMelbourneVIC 3800Australia CSIRO Materials Science and Engineering Bayview AvenueClaytonVIC 3168Australia Julius Wolff Institute and Berlin Brandenburg Center for Regenerative Therapies Charité–Universitätsmedizin BerlinAugustenburger Platz 113353 BerlinGermany Laboratory of Metal Physics and Technology Department of MaterialsETH Zurich8093 ZurichSwitzerland

Biodegradable implants are critical for regenerative orthopaedic procedures,but they may suffer from too fast corrosion in human-body *** necessitates the synthesis of a suitable coating that may improve the corrosion resistance of these implants without compromising their mechanical *** this study,an AZ91 magnesium alloy,as a representative for a biodegradable Mg implant material,was modified with a thin reduced graphene oxide(RGO)-calcium carbonate(CaCO_(3))composite *** analytical and in-vitro electrochemical characterization reveals that this coating significantly improves the corrosion resistance and mechanical integrity,and thus has the potential to greatly extend the related application field.

关键词： Graphene coating Biodegradable implant Hydroxyapatite Corrosion Magnesium alloy

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国际著名银屑病(牛皮癣)临床医学研究专家

国际著名银屑病(牛皮癣)临床医学研究专家

Effect of alloy composition and heat treatment on mechanical performance of 6xxx aluminum alloys

2009全国中西医结合皮肤性病学术会议

作者：米高澳洲monash大学

1994年米高博士使澳洲墨尔本Alfred医院皮肤临床工作获得RACGP质量保证体系的认证,证书号为94/03/0706。同年,米高博士成为新南威尔斯省的补充药物协会的会会员,

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Transactions of Nonferrous Metals Society of China 2014年第7期24卷 2174-2178页

作者：钟皓 Paul ROMETSCH Yuri ESTRIN ARC centre of Excellence for Design in Light Metals Department of Materials EngineeringMonash University centre for Advanced Hybrid Materials Department of Materials EngineeringMonash University

The effect of alloy composition and heat treatment, including natural ageing and pre-ageing, on the mechanical performance of eight 6xxx alloys designed with systematically varying Si, Mg and Cu contents was studied. The results show that not only the alloy composition and heat treatment before forming influence the formability, but also they have an effect on the paint bake response of the alloys. Increasing the alloy Si content, decreasing Mg/Si ratio and adding 0.3% Cu （mass fraction） were generally found to improve the tensile ductility and formability of the alloys studied, while pre-ageing was found to decrease these properties. A full property profile of these alloys in terms of strength, tensile ductility, work hardening, strain rate sensitivity, forming limit and paint bake response was presented.

关键词： 6xxx aluminum alloys automotive sheet heat treatment formability mechanical performance