检索结果-南通市图书馆

Chemical component and antimicrobial activity of volatile oil of Calycopteris floribunda

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2009年第6期16卷 931-935页

作者：刘佳佳杨栋梁张艳袁遥曹福祥赵建明彭潇波 School of Chemistry and Chemical Engineering Central South University School of Biotechnology Central South University of Forestry and Technology Botanical Garden of Rare and Endangered Plants

The volatile oil of leaves and barks of Calycopteris floribunda was examined by gas chromatography-mass spectrometry (GC-MS). 52 volatile chemical components in leaves were identified. The antimicrobial assay of oils in the leaves and barks was carried out by disk diffusion method in vitro. The major components (mass fraction) in leaves are caryophyllene oxide (13.79%),n-hexadecanoic acid (11.91%) and β-caryophyllene (10.45%). Ten constituents are identified accounting for about 99.98% of the total volatile oil in the bark. Among these components,n-hexadecanoic acid (59.18%),linolic acid (12.70%) and butyl octyl phthalate (8.21%) are the major constituents. The oils exhibit strong antimicrobial activity and display more potent against bacteria than fungi.

关键词： Calycopterisfloribunda volatile oil antimicrobial activity GC-MS

Components of volatile oil from Water-caltrop and Their Anti-tumor Effect in vitro

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2009年第1期25卷 56-59页

作者： ZHAO Wen-jing NIU Feng-lan LI Jing DONG Qing HUANG Zhan-you School of Public Health Jilin University Changchun 130021 P. R. China

The volatile oil was extracted from water caltrop by steam distillation; it was then analyzed by GC-MS to obtain 16 components, 8 of which were identified. Apocynin was the most abundant one, accounting for 81.41% of the total oil. The in vitro inhibitory effects of the volatile oil on SMMC-7721, MCF-7, Hela, HL-60 cells, and human peripheral blood mononuclear cells（PBMC） were investigated via the MTT method. The morphological changes of the tumor cells were observed and the apoptosis of HL-60 cells was detected by flow cytometry. The proliferation of the tumor cells could be significantly inhibited and the apoptosis of HL-60 cells could be induced by the volatile oil. The proliferation inhibition effect of the volatile oil on HL-60 tumor cells and the induction of the apoptosis of ilL-60 cells had dose-dependent feature.

关键词： Water caltrop volatile oil Tumor Apoptosis

Using the Box-Behnken Response Surface Method to Optimize the Preparation and Characterization of Lavender and Fennel volatile oilβ-cyclodextrin Form Inclusion Complex

在线全文

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2018年第2期4卷 54-61页

作者： Yuan-Yuan Liu Guo-Song Zhang Guang-Wei Zhu Ai-Ni-Wa-Er Aikemu Jia-Jia Ai Dong-Xun Li The National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine Jiangxi University of Traditional Chinese Medicine Chinese Medicine Research Institute Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Basic Medical College Xinjiang Medical University

Objective:The objective of this study is to study the best inclusion technology of Lavender-and fennel-mixed volatile oil by beta?cyclodextrin(β-CD) and characterize the final product ***:Using the saturated water solution method,the volatile β-CD inclusion complex was *** effect of volatile oil weight ratio,inclusion temperature and inclusion time on the inclusive quality was studied by measuring the yield of inclusion and inclusion rate of volatile oil as evaluation *** preparation method of inclusion complex was then optimized by the Box-Behnken response surface *** inclusion complex was characterized by ultraviolet spectrophotometry,thin-layer chromatography,thermogravimetry and differential thermal analysis,and the microscopic imaging ***:The optimized conditions were the weight ratio of β-CD to volatile oil was 8.13:1(g/ml).The inclusion temperature was 44°*** inclusion time was 1 ***:We were able to produce an inclusion complex with high inclusion rate of volatile oil and high yield of inclusion using the preparation method mentioned ***,the method can also improve the stability of volatile oil in abnormal savda *** study can provide a good reference for the development of new preparations.

关键词： Fennel inclusion complex lavender response surface method volatile oil β-cyclodextrin

Pharmacological effects of volatile oil from chrysanthemum and its associated mechanisms:a review

在线全文

学校读者我要写书评

暂无评论

Acupuncture and Herbal Medicine 2024年第1期4卷 79-91页

作者： Jing Zhang Weiqiang Su Nina Filipczak Ying Luo Anping Wan Yao He Shijuan Yan Xiang Li Ming Yang Key Laboratory of Modern Preparation of TCM Ministry of EducationJiangxi University of Chinese MedicineNanchangChina Center for Pharmaceutical Biotechnology and Nanomedicine Northeastern UniversityBostonUSA National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine Jiangxi University of Chinese MedicineJiangxi University of Chinese MedicineNanchangChina

volatile oil(VO)is the main chemical component of common plants in Chrysanthemum genus,and it possesses several beneficial pharmacological properties,including bacteriostatic,antioxidant,anti-tumor,anti-inflammatory,antipyretic,analgesic,antiosteoporotic,antihypertensive,sedative,and hypnotic *** date,research on the effective components of Chrysanthemum extract has mainly focused on flavonoids,whereas limited data are available on the chemical constituents and underlying mechanisms of action of the VO *** this review,the pharmacological activities and mechanisms of VO are comprehensively reviewed with the aim of providing a foundation for further development for medicinal,aromatherapy,and diet therapy applications.

关键词： Action mechanisms Chrysanthemum Pharmacological activity volatile oil

volatile oil from Litsea lancilimba Merr.: a review of its chemical structure and biological activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Traditional Medicines 2022年第4期17卷 181-185页

作者： Yijie Zhang Ming Bai Weiyu Zhou Xiaoxiao Huang Shaojiang Song Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research&Development Liaoning ProvinceSchool of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyang 110016China

Litsea lancilimba *** a Cinnamomum plant of *** investigations of the Litsea lancilimba *** resulted in the isolation of volatile oil,flavonoid glycosides,tannins,alkaloids,lignans,organic acids and so *** have showed that volatile oil is the main chemical *** trials have demonstrated the efficacy of Litsea lancilimba *** strengthening the function of *** fruits have also been demonstrated to possess anti-inflammatory and bacteriostatic *** review deals mainly with the chemical structure and biological activities of Litsea lancilimba ***.

关键词： Litsea lancilimba Merr. volatile oil chemical composition pharmacological activity

Gas Chromatography-Based Fingerprinting and Chemical Pattern Recognition of Rosa multiflora volatile oil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Agricultural Science and Technology(A) 2017年第1期7卷 31-38页

作者： Tuniyazi Gulimeikereyi Ablajan Nurpida Malike Dilinuer Hailaxi Alai Department of Chemistry and Chemical Engineering Xinjiang Normal University Urumuqi 830054 China

In this paper, gas chromatography-mass spectrometry （GS-MS） was used to build the standard fingerprint of volatile oil from Rosa multiflora Thunb. from 12 different habitats. Fourteen components in the volatile oil were identified as the indicator components ofR. multiflora, of which one was selected as the standard. The GC analysis conditions used for fingerprinting afford a very good separating effect. The similarity of the 12 volatile oils from R. multiflora Thunb. was more than 0.84, and the precision, stability and repeatability of the fingerprints were quite good. It could be concluded that the fingerprints can be used as the standard and as a quality control method for medicinal materials from R. multiflora Thunb..

关键词： Rosa multiflora volatile oil GC-MS fingerprinting main component.

Identification of volatile oil Components of Nardostachys jatamansi DC. Root and Rhizome,Herb

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Medicinal Plant 2018年第2期9卷 11-15,21页

作者： Qian JIN Fang XIAO Pei QUN Ying Li Yuan LIU College of Pharmacy Southwest Minzu University Ethnic Medicine Institute Southwest Minzu University

[Objectives] volatile oil components of traditional drug use site " root and rhizome" of N. jatamansi and herb were identified and contrasted,which aimed to provide the basis for rationally using wild N. jatamansi resource. [Methods]volatile oil components from different sites of N. jatamansi were identified and isolated by GC-MS. [Results] There were 56 kinds of volatile oil components from different sites of N. jatamansi,in which 39 components from herb of N. jatamansi,39 components from root and rhizome of N. jatamansi,and there were 22 common components. But 1 component in higher concentration had obvious difference. [Conclusions] The herb of N. jatamansi could not completely replace " root and rhizome" of N. jatamansi as the medicine,which was consistent with prior detection result of each physicochemical index from different sites of N. jatamansi. The research could provide the reference for making quality standard of N. jatamansi medicine and rational basis for its further research and development.

关键词： Nardostachys jatamansi volatile oil Root and rhizome Herb Component identification

Mechanism of volatile oil from Chuanxiong(Chuanxiong Rhizoma)-Suhexiang(Styrax)-Bingpian(Borneolum)in treating angina pectoris based on network pharmacology and its protective effects on myocardial damage in rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Digital Chinese Medicine 2021年第3期4卷 202-213页

作者： LEI Zhiqiang WANG Chaoping Abid Naeem YIN Ning CAO Meifang LUO Jing Clinical Medical College of Jiangxi University of Chinese Medicine NanchangJiangxi 330006China School of Pharmacy Jiangxi University of Chinese MedicineNanchangJiangxi 330006China The Islamia University of Bahawalpur Punjab 63100Pakistan Key Laboratory of Modern Chinese Medicine Preparation Ministry of EducationNanchangJiangxi 330006China State Key Laboratory of Innovative Drugs and Pharmaceutical Equipment with High Efficiency Energy Saving and Consumption ReductionNanchangJiangxi 330006China

Objective To explore the pharmacodynamic material basis and mechanism of action of volatile oil from Chuanxiong(Chuanxiong Rhizoma)-Suhexiang(Styrax)-Bingpian(Borneolum)(hereinafter referred to as C-S-B volatile oil)in treating angina pectoris based on network pharmacology and to detect its protective effects against rat myocardial *** Gas chromatography-mass spectrometry(GC-MS)was used to determine the constituents of volatile oils from Chuanxiong(Chuanxiong Rhizoma),Suhexiang(Styrax),and Bingpian(Borneolum),and the targets of the three main constituents were found predicted and screened using the PharmMapper server,and Gene Cards and Coo LGe N *** STRING database and Cytoscape software were used to draw the protein-protein interaction(PPI)network,RStudio software was used to analyze Gene Ontology(GO)and Kyoto Encyclopedia of Genome and Genome(KEGG)pathways,and Cytoscape software was used to construct the component-target-pathwaydisease *** rat model of myocardial injury was established by intraperitoneal injection of a large dose of isoprenaline *** continuous intervention with C-S-B volatile oil for 14 d,the ejection fraction(EF)and short axis shortening rate(FS)of the left ventricle were *** indices of myocardial damage were detected after hematoxylin-eosin(HE)*** Fifteen volatile oil components from the C-S-B formula were *** are 470 targets of these volatile oil components and 401 angina-related *** are 28 core targets,including CHRM4,ADRA1 A,FGFR1,CHRM2,CYP2 A6,CHRM5,CHRM1,CHRM3,HDAC2,and MPO,etc..The results of the KEGG analysis indicated that the C-S-B formula probably interferes with the following pathways:neuroactive ligand-receptor interactions,calcium signaling,cytochrome P450 metabolism of heteropoietin,among *** results of animal experiments showed that the C-S-B formula essential oil could significantly improve the following myocardial indices in rats with

关键词： Chuanxiong(Chuanxiong Rhizoma) Suhexiang(Styrax) Bingpian(Borneolum) volatile oil Angina pectoris Gas chromatography-mass spectrometry(GC-MS) Network pharmacology Myocardial injury Rat model

Study on the interaction between volatile oil components and skin lipids based on molecular docking techniques

在线全文

学校读者我要写书评

暂无评论

Digital Chinese Medicine 2024年第2期7卷 148-159页

作者： REN Weishuo WULAN Tuya DAI Xingxing ZHANG Yingying JIA Mingyue FENG Minfang SHI Xinyuan School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing 102488China Key Laboratory for Production Process Control and Quality Evaluation of Traditional Chinese Medicine Beijing Municipal Science&Technology CommissionBeijing 102488China School of Life Sciences Beijing University of Chinese MedicineBeijing 100029China

Objective To analyze the interactions between different structural types of volatile oil compo-nents(VOCs)and skin lipid molecules;and investigate the mechanism of volatile oil in Chi-nese materia medica(VOCMM)as penetration *** In this study;210 different structural types of VOCs were selected from the VOCMM penetration enhancer database;and the molecular docking experiments were conducted with three main lipid molecules of skin:ceramide 2(CER2);cholesterol(CHL);and free fatty acid(FFA).Each VOC was docked individually with each lipid *** analysis was used to explore the relationship between the binding energy of VOCs and their molecular *** specific pathogen-free(SPF)Sprague Dawley(SD)rats were randomly divided in-to Control;Nootkatone;and 3-Butylidenephthalide groups for in vitro percutaneous experi-ments;with three rats in each *** donor pool solutions were 3%gastrodin;3%gas-trodin+3%nootkatone;and 3%gastrodin+3%3-butylidenephthalide;*** pen-etration enhancing effects of VOCs with higher binding energy were evaluated by comparing the 12-hour cumulative percutaneous absorption of gastrodin(Q12;µg/cm²).Results(i)Most of the VOCs were non-hydrogen bonded to the hydrophobic parts of CHL and FFA;and hydrogen bonded to the head group of *** them;sesquiterpene ox-ides showed the most pronounced binding affinity to *** VOCs with 2-4 rings(in-cluding carbon rings;benzene rings;and heterocycles)demonstrated stronger binding affini-ty for three skin lipid molecules compared with the VOCs without intramolecular rings(P<0.01).(ii)According to the cluster analysis;most of the VOCs that bond well to CER2 had 2-3 intramolecular *** non-oxygenated VOCs were bonded to CER2 in a hydrophobic *** oxygenated VOCs were mostly bonded to CER2 by hydrogen bonding.(iii)The results of Franz diffusion cell experiment showed that the Q12 of Control group was 260.60±25.09µg/cm2;and the transdermal absorption o

关键词： Chinese materia medica volatile oil Stratum corneum lipids Transdermal penetration-enhancing effects Molecular docking Ceramide 2(CER2) Penetration enhancers