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Eye and Vision 2021年第1期8卷 385-395页

作者： Jin Li Yue Zhou Feng Chen Yingzi Li Rong Zhou Chaoming Wu Huankai Yu Zhiyang Lin Ce Shi Gu Zheng Yilei Shao Qi Chen Fan Lu Meixiao Shen School of Ophthalmology and Optometry Wenzhou Medical University270 Xueyuan RoadWenzhou 325027ZhejiangChina The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University Wenzhou 325027ZhejiangChina Department of Ophthalmology The Affiliated Hospital of Yangzhou UniversityYangzhou 225000JiangsuChina

Purpose:We investigated the effects of retinal ischemia,neurodegeneration,and subclinical edema on best-corrected visual acuity(BCVA)in the early stages of diabetic retinopathy(DR).Methods:Ischemia was evaluated by the microvascular parameters measured by optical coherence tomography *** and subclinical edema were identified by the intraretinal layer thickness obtained by optical coherence *** with nonproliferative diabetic retinopathy(n=132)from 89 patients were *** were classified as having normal BCVA(n=88[66.7%],Snellen equivalent≥20/20)or decreased BCVA(n=44[33.3%],Snellen equivalentvisual *** proportions of ischemia and neurodegeneration were significantly higher in eyes with decreased BCVA than in eyes with normal BCVA(P=0.001 and P=0.004,respectively).Conclusion:During the natural course of the early stages of DR,ischemia and neurodegeneration were the main disease pathways associated with visual acuity,and the mechanisms varied among patients.

关键词： Diabetic retinopathy visual acuity Optical coherence tomography Ischemia Neurodegeneration

visual acuity evaluated by pattern-reversal visual-evoked potential is affected by check size/visual angle

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Neuroscience Bulletin 2012年第6期28卷 737-745页

作者： Xiping Chen Qianqian Li Xiaoqin Liu Li Yang Wentao Xia Luyang Tao Shanghai Key Lab of Forensic Medicine Forensic Brain Laboratory Department of Forensic SciencesSoochow University Department of Forensic Medicine Wannan Medical College

Objective To systemically explore the range of visual angles that affect visual acuity, and to establish the relationship between the P 1 component （peak latency -100 ms） of the pattern-reversal visual-evoked potential （PRVEP） and the visual acuity at particular visual angles. Methods Two hundred and ten volunteers were divided into seven groups, according to visual acuity as assessed by the standard logarithmic visual acuity chart （SLD-II）. For each group, the PRVEP components were elicited in response to visual angle presentations at 8°, 4°, 2°, 1°/60＇, 30＇, 15＇, and 7.5＇, in the whiteblack chess-board reversal mode with a contrast level of 100% at a frequency of 2 Hz. visual stimuli were presented monocularly, and 200 presentations were averaged for each block of trials. The early and stable component P1 was recorded at the mid-line of the occipital region （Oz） and analyzed with SPSS 13.00. Results （1） Oz had the maximum Pl amplitude; there was no significant difference between genders or for interocular comparison in normal controls and subjects with optic myopia. （2） The P1 latency decreased slowly below 30＇, then increased rapidly. The P1 amplitude initially increased with check size, and was maximal at -1° and -30＇. （3） The P1 latency in the group with visual acuity 〈0.2 was signifi- cantly different at 8°, 15＇ and 7.5＇, while the amplitude differed at all visual angles, compared with the group with normal vision. Differences in P1 for the groups with 0.5 and 0.6 acuity were only present at visual angles 〈1°. （4） Regression analysis showed that the P1 latency and amplitude were associated with visual acuity over the full range of visual angles. There was a moderate correlation at visual angles 〈30＇. Regression equations were calculated for the P1 components and visual acuity, based on visual angle. Conclusion （1） visual angle should be taken into consideration when exploring the function of the visual pathway, especially visual acuity. A visual angle -60＇ mig

关键词： visual acuity visual angle pattern-reversal visual-evoked potential check size regression equation

visual acuity and endothelial cell density with respect to the graft thickness in Descemet's stripping automated endothelial keratoplasty: one year results

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 974-979页

作者： Banu Torun Acar Mehmet Orcun Akdemir Suphi Acar Ophthalmology Clinic Haydarpasa Numune Research and Education Hospital Department of Ophthalmology School of MedicineBulent Ecevit University

AIM: To evaluate the visual acuity and endothelial cell density according to the thickness in Descemet’s stripping automated endothelial keratoplasty(DSAEK)one year after ***: DSAEK patients’ data were reviewed. Thirty seven eyes of 37 patients who underwent DSAEK for pseudophakic bullous keratopathy(PBK) were included in this study. Graft thickness was measured with optical coherence tomography(OCT) 12 mo after DSAEK. Eyes were divided into 3 groups based on the graft thickness:thick(>200 μm), medium-thick(150-200 μm) and thin(visual acuity(BCVA),endothelial cells density(ECD) and complications were assessed and comparisons were done between ***: Median thickness of postoperative grafts was 188(range 73-317 μm). There was no significant difference in age, sex, preoperative BCVA, or follow-up period between DSAEK groups. At postoperative 12 mo,mean BCVA was 0.28±0.10 in thick graft group, 0.52±0.08 in medium-thick graft group, and 0.72 ±0.06 in thin graft group. Thin grafts showed better postoperative BCVA as compared with the medium-thick and thick grafts(P =0.001). Thick graft group had 1637.44 ±88.19-mm2,medium thick graft had 1764.50±34.28-mm2 and thin graft group had 1845.30 ±65.62-mm2. Thin graft group had better ECD at 12 mo after surgery(P =0.001).CONCLUSION: Thin grafts after DSAEK ensure better visual rehabilitation. Eyes with thin grafts had significantly lesser loss of ECD compared to eyes withmedium-thick and thick grafts one year after surgery.

关键词： Corneal endothelial cell density Descemet's stripping endothelial keratoplasty graft thickness visual acuity

OCTA characteristics in non-arteritic central retinal artery occlusion and correlation with visual acuity

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International Journal of Ophthalmology(English edition) 2024年第2期17卷 289-296页

作者： Hong-Xia Gong Bin Wu Shi-Yong Xie Wei Zhang Song Chen Tianjin Key Lab of Ophthalmology and visual Science Department of Ophthalmology for Integrated Traditional Chinese and Western MedicineTianjin Eye HospitalTianjin 300020China Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300010China Eye Hospital Affiliated to Nankai University Tianjin 300020China

AIM:To observe the retinal and choroidal circulations in patients with non-arteritic permanent central retinal artery occlusion(NA-CRAO)via optical coherence tomography angiography(OCTA)and analyze their correlation with visual ***:Sixty-two eyes with clinically confirmed acute NA-CRAO were included in the study and divided into:A type(mild n=29),B type(moderate n=27)and C type(severe n=6)based on the degree of visual loss,retinal edema,and arterial blood flow delay in fundus fluorescence angiography(FFA).Contralateral healthy eyes were used as the control ***-corrected visual acuity(BCVA),slit lamp microscopy,indirect ophthalmoscopy,fundus color photography,OCTA,and FFA were ***’s correlation analysis was used to determine the correlations between retinal and choroidal vessels and visual ***:There were no statistically significant differences in age,gender,and intraocular pressure among the three types and the control group(P>0.05).Vessel density in deep capillary plexus(VD-DCP)significantly decreased(P<0.05)in all three types of NA-CRAO patients compared to the control *** density in superficial vascular plexus(VD-SVP)significantly decreased(P<0.05)in type A patients and choriocapillaris flow area significantly decreased(P<0.05)in type B and type C patients compared to the control group;while outer retinal flow areas significantly increased in the type A(P<0.05)and decreased in type C patients(P<0.05).The retinal thickness significantly increased in type C group(P<0.05).The VD-SVP at fovea in the type A was significantly lower than both of type B and *** VD-SVP at nasal parafovea in type A and B was significantly lower than type C(P<0.05).The logMAR BCVA of type A was significantly better than that of type B and C groups(P<0.05).Spearman’s correlation analysis showed that the logMAR BCVA was positively correlated with VD-SVP at fovea(r=0.679,P=0.031)and nasal parafovea(r=0.826,P=0.013).CONCLUSION:OCTA is valua

关键词： non-arteritic central retinal artery occlusion fundus fluorescence angiography optical coherence tomography angiography retinal vessel density visual acuity

Influence of severity and types of astigmatism on visual acuity in school-aged children in southern China

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International Journal of Ophthalmology(English edition) 2018年第8期11卷 1377-1383页

作者： Li-Li Wang Wei Wang Xiao-Tong Han Ming-Guang He Zhongshan Ophthalmic Center State Key Laboratory of OphthalmologySun Yat-Sen University

AIM： To investigate the influence of astigmatism on visual acuity in school-aged children, and to define a cutoff for clinically significant astigmatism. METHODS： This is a population-based, cross-sectional study. Among 5053 enumerated children aged 5-15 y in Guangzhou, 3729（73.8%） children aged 7-15 with successful cycloplegic auto-refraction（1% cyclopentolate） and a reliable visual acuity measurement were included. Ocular measurement included external eye, anterior segment, media and fundus and cycloplegic auto-refraction. Primary outcome measures included the relationship between severity and subtypes of astigmatism and the prevalence of visual impairment. Three criteria for visual impairment were adopted： best-corrected visual acuity（BCVA） ≤0.7, uncorrected visual acuity（UCVA） ≤0.5 or 〈0.7 in the right ***： Increases of cylinder power was significantly associated with worse visual acuity（UCVA： β=0.051, P〈0.01; BCVA： β=0.025, P〈0.001）. A substantial increase in UCVI and BCVI was seen with astigmatism of 1.00 diopter（D） or more. Astigmatism ≥1.00 D had a greater BCVI prevalence than cylinder power less than 1.00 D（OR=4.20, 95%CI： 3.08-5.74）, and this was also true for hyperopic, emmetropic and myopic refraction categories. Oblique astigmatism was associated with a higher risk of BCVI relative to with the rule astigmatism in myopic refractive category（OR=12.87, 95%CI： 2.20-75.38）.CONCLUSION： Both magnitude and subtypes of astigmatism influence the prevalence of visual impairment in school children. Cylinder ≥1.00 D may be useful as a cutoff for clinically significant astigmatism.

关键词： astigmatism visual acuity children population-based study

A new visual acuity test on touchpad for vision screening in children

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International Journal of Ophthalmology(English edition) 2020年第9期13卷 1436-1442页

作者： Elsa Di Foggia Noémie Stoll Hélène Meunier Adam Rimelé Pascal Ance Pierre-Henri Moreau Claude Speeg-Schatz Arnaud Sauer Ophthalmology Department CHU StrasbourgStrasbourgAlsace 67091France Ophthalmology Department CH ColmarColmarAlsace 68024France Cognitive and Adaptative Neuroscience Laboratory StrasbourgAlsace 67000France Plateforme SILABE Strasbourg UniversityAlsace 67207France

AIM:To validate a visual acuity(VA)test application on touchpad in the screening of pediatric population by comparing VA results obtained with conventional ***:A cohort of 101 patients,44 girls and 57 boys with a median of 6.5 years old(3-10 years of age),presenting for eye examinations in Ophthalmology Department(Strasbourg,France)between November 1st,2018,and February 1st,2019 were *** and binocular VA testing was performed on the subject using both a standard test and the touchpad application(Monoyer,"E"or,Pigassou depending of children s capacities).Patients were excluded if they were physically or mentally unable to use the *** duration of each tests,the painfulness,the comprehension,the attention of children during the test and test’s preferences were also ***:There was a good linear correlation and intra-class correlation coefficient[ICC=0.50(0.***.0.64)for binocular acuity,0.74(0.***.0.82)for right eyes and 0.525(0.***.0.66)for left eye].The standard errors of measurement were very low(0.***.0.05.0.08 for binocular VA,right eyes VA and left eyes VA,respectively).There was no difference between two tests for right eye(P=0.126);left eye(P=0.098)and binocular acuity(P=0.085).Non inferiority was proved for all binocular[-0.06(-0.09.-0.03)],right eye[-0.04(-0.07.-0.01)]and left eye[-0.06(-0.09,-0.02)]*** sensitivity and specificity,which correspond to the ability for our app to detect amblyopia,were 92%and 80%***:Our touchpad application represents an efficient and valid test of VA in children with a high specificity to detect visual impairment.

关键词： visual acuity application screening children

Forensic Study on Objective Evaluation of visual acuity of Ametropia with the Event-related Potential P3

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Current Medical Science 2023年第3期43卷 609-614页

作者： Fu-quan JIA Fang-liang LUO Yan-he XIONG Long-long CHENG Zhi-qiang DANG Ji-hui LIU Department of Forensic Medicine Inner Mongolia Medical UniversityHohhot 010059China Judicial Authentication Research Institute Liaoning UniversityShenyang 110036China Shanghai Love Nursing Station Shanghai 200030China Affiliated Zhongshan Hospital of Dalian University Dalian 116001China Dian Regional Forensic Science Institute(Nei Mongol) Hohhot 010041China

Objective In this study,we aimed to assess the characteristics of the P3 component from an event-related potential(ERP)that was induced by visual acuity(VA)***,we sought to provide electrophysiological evidence for the objective evaluation of *** We recruited 32 participants with myopia-related *** reported no other ocular diseases and had an uncorrected VA of 4.0 in both *** used the block letter“E”at different visual angles and orientations as the graphic *** oddball paradigm,consisting of 4 modules,was used for ERP *** standard stimuli of each module were identical,with a visual angle of 1°15′.The visual angles of the target stimuli were 1°15′,55′,24′,and 15′.The VA test was performed on each eye separately for all participants,and all characteristics of the P3 component were *** There was no significant difference in the P3 peak letencies between the target stimulation angle 1°15′group and the 55′group,or between the target stimulation angle 24′group and the 15′*** was a significant difference in the P3 peak letencies between the target stimulation angle 1°15′group and the 24′group as well as the 15′*** was a significant difference in the P3 peak letencies between the target stimulation angle 55′group and the 24′group as well as the 15′*** significant differences were observed in the P3 amplitude between *** In the oddball paradigm,P3 elicitation indicated a cognitive response to the target *** data showed that the characteristics of P3 can be used as an objective evaluation of VA.

关键词： event-related potential P3 visual acuity forensic medicine amplitude

Comparison of visual acuity of the patients on the first day after sub-Bowman keratomileusis or laser in situ keratomileusis

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International Journal of Ophthalmology(English edition) 2016年第3期9卷 448-452页

作者： Wei Zhao Ting Wu Ze-Hong Dong Jie Feng Yu-Feng Ren Yu-Sheng Wang Department of Ophthalmology Xijing Hospitalthe Fourth Military Medical University Out-patient Department the Second Artillery Engineering University

AIM：To compare recovery of the visual acuity in patients one day after sub-Bowman keratomileusis（SBK）or laser in situ keratomileusis（LASIK）.· METHODS：Data from 5923 eyes in 2968 patients that received LASIK（2755 eyes） or SBK（3168 eyes） were retrospectively *** eyes were divided into 4groups according to preoperative spherical equivalent：between-12.00 to-9.00 D,extremely high myopia（n =396,including 192 and 204 in SBK and LASIK groups,respectively）;-9.00 to-6.00 D,high myopia（n=1822,including 991 and 831 in SBK and LASIK groups,respectively）,-6.00 to-3.00 D,moderate myopia（n=3071,including 1658 and 1413 in SBK and LASIK groups,respectively）,and-3.00 to 0.00 D,low myopia（n =634,including 327 and 307 in SBK and LASIK groups,respectively）.Uncorrected logMAR visual acuity values of patients were assessed under standard natural *** of variance was used for comparisons among different groups.· RESULTS：Uncorrected visual acuity values were0.0115±0.1051 and 0.0466±0.1477 at day 1 after operation for patients receiving SBK and LASIK,respectively（P〈0.01）;visual acuity values of 0.1854±0.1842,0.0615±0.1326,-0.0033±0.0978,and-0.0164±0.0972 were obtained for patients in the extremely high,high,moderate,and low myopia groups,respectively（P〈0.01）.In addition,significant differences in visual acuity at day 1 after operation were found between patients receiving SBK and LASIK in each myopia subgroup.· CONCLUSION：Compared with LASIK,SBK is safer and more effective,with faster ***,SBK is more likely to be accepted by patients than LASIK for better uncorrected visual acuity the day following operation.

关键词： sub-Bowman keratomileusis laser in situ keratomileusis visual acuity myopia recovery

Adaptive Rendering Based on visual acuity Equations

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High Technology Letters 2001年第2期7卷 14-18页

作者：纪庆革 Hong Bingrong Wang Dongmu Department of Computer Science Engineering Harbin Institute of Technology Beijing Simulation Center

A new method of adaptable rendering for interaction in Virtual Environment(VE) through different visual acuity equations is proposed. An acuity factor equation of luminance vision is first given. Secondly, five equations which calculate the visual acuity through visual acuity factors are presented, and adaptive rendering strategy based on different visual acuity equations is given. The VE system may select one of them on the basis of the host’s load, hereby select LOD for each model which would be rendered. A coarser LOD is selected where the visual acuity is lower, and a better LOD is used where it is higher. This method is tested through experiments and the experimental results show that it is effective.

关键词： visual acuity visual acuity factor Adaptive rendering Levels of detail (LOD) Virtual environments (VEs)

Contrast visual acuity after multifocal intraocular lens implantation: aspheric versus spherical design

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International Journal of Ophthalmology(English edition) 2014年第1期7卷 100-103页

作者： Jun-Hua Li Yi-Fan Feng Yun-E Zhao Yin-Ying Zhao Lei Lin School of Ophthalmology and Optometry the Eye Hospital of Wenzhou Medical University Zhejiang Eye Hospital Department of Ophthalmology Zhongshan HospitalFudan University

AIM: To evaluate contrast visual acuity(CVA) after implantation of an aspheric apodized diffractive intraocular lens(IOL) or a spherical apodized diffractive IOL in cataract surgery. ·METHODS: This prospective randomized controlled study with a 12-month follow-up compared the results of cataract surgery with implantation of an aspheric AcrySof ReSTOR SN6AD3 IOL(30 eyes) and a spherical AcrySof ReSTOR SN60D3 IOL(30 eyes). CVA with best distance correction was measured at 4 contrast levels(100%,25%,10% and 5%) under 3 levels of chart luminance [250,85 and 25 candelas per square meter(cd/m2)] using a multi-functional visual acuity tester(MFVA-100). ·RESULTS: At 12 months after surgery,there were no statistically significant differences in 100% CVA and 25% CVA under 250cd/m2(P100% =0.875 and P25% =0.057) and 85cd/m2(P100% =0.198 and P25% =0.193) between the aspheric group and the spherical group. However,the 10% CVA and 5% CVA were significant better in aspheric group than spherical group under 250cd/m2(P10% =0.042 and P5% = 0.007) and 85cd/m2(P10% =0.002 and P5%=0.039). Under the luminance level of 25cd/m 2,no significant differences was found in the 100% CVA between the 2 group(P100% = 0.245),while aspheric group had better visual acuity in the remaining 3 contracts(P25% =0.023,P10% =0.026 and P5% = 0.002,respectively). ·CONCULSION: The aspheric AcrySof ReSTOR SN6AD3 IOL provided patients with better low-contrast visual acuity than the spherical AcrySof ReSTOR SN60D3 IOL.

关键词： cataract surgery intraocular lens contrast sensitivity visual acuity