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Biomedical and Environmental Sciences 2018年第6期31卷 425-437页

作者： LIU Zhen PANG Shao Jie MAN Qing Qing WANG Jing Zhong ZHAO Wen Hua ZHANG Jian National Institute for Nutrition and Health Chinese Center for Disease Control and Prevention

Objective undernutrition is highly prevalent among older people. The aim of this study was to estimate the prevalence of undernutrition in elderly Chinese residents and explore the relationship between undernutrition and dietary factors. Methods Data were collected from 2,552 elderly people aged 75 years and over from the Chinese Nutrition and Health Surveillance during 2010-2012 using questionnaires, anthropometric measurement, and individual consecutive 3-day 24-hour dietary records. Results The present study showed that 10.5% of participants had undernutrition. The prevalence was higher among the population living in rural areas, those living in the South region, those who smoked, and those with low income levels. Most participants failed to meet the Chinese Dietary Reference Intakes for energy（66.1%） and protein（72.1%）. When comparing quartiles of food intake, high rice consumption [odds ratio（OR） = 2.44, 95% confidence interval（CI）： 1.35-4.40）], animal oil intake（OR = 1.60, 95% CI： 1.18-2.17）, and high fat intake from animal sources（OR = 1.56, 95% CI： 1.06-2.31） were positively associated with underweight whereas high wheat consumption（OR = 0.44, 95% CI： 0.26-0.74）, a proper proportion（24%-32%） of energy intake from fat（OR = 0.54, 95% CI： 0.35-0.83）, and high fat intake from plant sources（OR = 0.67, 95% CI： 0.46-0.99） were inversely *** The prevalence of undernutrition was high among elderly Chinese people, especially in rural areas. Dietary factors, such as high consumption of rice, were associated with undernutrition.

关键词： undernutrition Dietary Elderly adults Cross-sectional study

Prevalence and risk factors of undernutrition among schoolchildren in the Plateau Central and Centre-Ouest regions of Burkina Faso

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Infectious Diseases of Poverty 2017年第1期6卷 140-153页

作者： Severine Erismann Astrid M.Knoblauch Serge Diagbouga Peter Odermatt Jana Gerold Akina Shrestha Grissoum Tarnagda Boubacar Savadogo Christian Schindler Jürg Utzinger Gueladio Cisse Swiss Tropical and Public Health Institute P.O.BoxCH-4002 BaselSwitzerland University of Basel P.O.BoxCH-4003 BaselSwitzerland Institut de Recherches en Sciences de la Sante P.O.Box 7192Ouagadougou 03Burkina Faso Kathmandu University P.O.Box 625045200 DhulikhelNepa

Background:Multiple factors determine children’s nutritional status,including energy and nutrient intake,recurrent infectious diseases,access(or lack thereof)to clean water and improved sanitation,and hygiene practices,among ***“Vegetables go to School:improving nutrition through agricultural diversification”(VgtS)project implements an integrated school garden programme in five countries,including Burkina *** aim of this study was to determine the prevalence of undernutrition and its risk factors among schoolchildren in Burkina Faso before the start of the ***:In February 2015,a cross-sectional survey was carried out among 455 randomly selected children,aged 8-14 years,in eight schools in the Plateau Central and Centre-Ouest regions of Burkina *** status was determined by anthropometric *** and intestinal protozoa infections were assessed using the Kato-Katz and a formalin-ether concentration method.A urine filtration technique was used to identify Schistosoma haematobium *** of anaemia was determined by measuring haemoglobin levels in finger-prick blood *** were administered to children to determine their knowledge of nutrition and health and their related attitudes and practices(KAP).Questionnaires were also administered to the children’s caregivers to identify basic household socio-demographic and economic characteristics,and water,sanitation and hygiene(WASH)*** determine the factors associated with schoolchildren’s nutritional status,mixed logistic regression models were *** and associations were considered statistically significant if P-values were below ***:Complete datasets were available for 385 *** prevalence of undernutrition,stunting and thinness were 35.1%,29.4%and 11.2%,*** multivariable analysis revealed that undernutrition was associated with older age(i.e.12-14 years compared to<12 years;adjusted odds ratio(aOR)=3

关键词： Anaemia Burkina Faso Intestinal parasitic infections School garden undernutrition Water sanitation and hygiene(WASH)

undernutrition in Adults Hospitalized Patients: Magnitude and Associated Factors at the University Hospital of Bobo-Dioulasso

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Open Journal of Epidemiology 2019年第1期9卷 27-35页

作者： Léon G. Blaise Savadogo Seydou Traoré Clément Z. Meda Joseph Bamouni Department of Epidemiology and Public Health Child and Mother Health Nutrition and Survival Unit Institut Supérieur des Sciences de la Santé Bobo Dioulasso Burkina Faso CHUSS (University Hospital of Bobo Dioulasso) Bobo-Dioulasso Burkina Faso

Background: Despite numerous advances in medicine and clinical care, in developing countries, adult undernutrition is overlooked and not considered as a sufficient medical priority. The objective of this study was to identify the magnitude of adult undernutrition and its associated factors in hospitalized patients. Methods: Cross-sectional study, performed in the university hospital in Bobo-Dioulasso, from August to September 2016, in a sample of 244 adult individuals. Patients were included in the study consecutively to their admission. A structured questionnaire was applied consisting of anthropometric, clinical and dietary data. The patients were evaluated and dichotomized into undernourished and non-undernourished. The rate of undernutrtion was reported using and associated factors were tested using the unadjusted crude Odds ratios (COR) with 95% confidence interval (95% CI) and the Chi-square test. Results: undernutrition occurred in 32.4% of the sample and at the univariate analysis, the variables associated with undernutrition were: recent and involuntary weight loss (COR = 2.58, 95% CI = 1.45 - 4.59, p Conclusion: Adult undernutrition is common in hospitalized patients. A proper early diagnosis and therapy need to be considered as medical priority of the entire healthcare team that treats adult’s inpatients.

关键词： Adult undernutrition Inpatients

Comparison of undernutrition Prevalence of Children under 5 Years in China between 2002 and 2013

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Biomedical and Environmental Sciences 2016年第3期29卷 165-176页

作者： YU Dong Mei ZHAO Li Yun YANG Zhen Yu CHANG Su Ying YU Wen Tao FANG Hong Yun WANG Xun YU Dan GUO Qi Ya XU Xiao Li FANG Yue Hui ZHAO Wen Hua YANG Xiao Guang DING Gang Qiang LIANG Xiao Feng National Center for Nutrition and Health Chinese Center for Disease Control and PreventionBeijing 100050China United Nations Children's Fund Beijing 100600China Chinese Center for Disease Control and Prevention Beijing 102206China

Objective To describe the undernutrition status of children under 5-year in China, and study the trend between 2002 and 2013. Methods The study was based on two national surveys. undernutrition was determined against WHO＇s 2006 growth standards. The prevalence in 2013 and 2002 was weighted by China sixth National Population Census （2010）. The relationship between undernutrition and gender/age groups/different areas use weighted logistic regression. Results The results indicated the overall prevalence of stunting, underweight, and wasting of Chinese children under S-year was 8.1%, 2.4%, and 1.9% in 2013, respectively. The prevalence of stunting was higher for children aged 12-47 month, while underweight was higher for children aged 48-59 month. The prevalence of undernutrition was higher in rural areas than in urban areas, especially in poor rural areas. There was a decline of stunting, underweight, and wasting between 2002 and 2013 among the children, with greater reduction in rural areas than in urban areas. Conclusion The prevalence of undernutrition of children under 5-year remains high in rural areas especially in poor rural areas in China. It is urgent to take action to control undernutrition in the vulnerable areas and subgroups.

关键词： undernutrition Prevelence Children under 5

Biological Markers of undernutrition and Risk of Complications in Children Hospitalized at the Teaching Hospital of Brazzaville

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Journal of Biosciences and Medicines 2022年第2期10卷 1-9页

作者： Christel Mikolélé-Bilombo Lucie Charlotte Atipo-Ibara Ollandzobo Steve Vassili Missambou Mandilou Thibaut Ocko Gokaba Lethso Clausina Mikolélé-Bilomb Ahoui Josué Simo Louokdom Martial Landry Miguel Etienne Mokondjimobe Donatien Moukassa Jean Robert Mabiala-Babela Ange Antoine Abena Jean-Rosaire Ibara Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Department of Pediatrics Teaching Hospital of Brazzaville Brazzaville Congo Department of Gastroenterology and Hepatology Teaching Hospital of Brazzaville Brazzaville Congo Cameroon Mountain University Douala Cameroon Denis Sassou Nguesso University Brazzaville Congo

Introduction: undernutrition is a condition frequently encountered in pediatrics. It leads to an increased morbidity and mortality regardless of the underlying condition or other risk factors such as age. In countries with limited resources such as ours, the diagnosis of undernutrition is often limited to the clinical presentation, and the contribution of biology is not often taken into account. Objectives: To establish the relationship between anthropometric parameters and biological markers in the diagnosis and classification of undernutrition and to assess the risk of infectious complications during undernutrition in children. Materials and Methods: A cross-sectional study conducted in Brazzaville among undernourished children aged 1 - 59 months between October 2018 and April 2019. Clinical diagnosis was based on WHO growth charts. The CRP, orosomucoid, albumin and transthyretin were obtained using the Cobas c311 analyzer, which enabled the calculation of Prognostic Inflammatory and Nutritional Index (PINI). The comparison of the means of the biological markers used the Student’s t-test, the risk of infectious complications the chi-square. The correlation of the diagnostic value of Z-score weight/height and PINI was also investigated. The significance level was set at 0.05. Results: Of the 95 children enrolled 63 (66.3%) were clinically severely malnourished, including 26 acute (41.3%) and 37 chronic (58.7%). The PINI revealed severe undernutrition in 85 children (89.4%) including 50 acute (58.8%) and 35 chronic (41.2%). CRP and orosomucoid were statistically higher in severe acute undernutrition (p Conclusion: Anthropometric parameters have a front-line advantage for assessing and classifying undernutrition. However, biological markers of undernutrition with PINI should be systematized in the diagnosis and management of undernutrition.

关键词： undernutrition Nutritional Marker Inflammatory Marker PINI Child Congo

Parabrachial neuron development: Effects of pre- and neonatal undernutrition in the rat

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Open Journal of Molecular and Integrative Physiology 2012年第4期2卷 112-118页

作者： Carmen Torrero Mirelta Regalado Lorena Rubio Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology University of Mexico Queretaro Mexico.

Pre-and neonatal fasting in the rat has been used as an experimental model to obtain information on how the newborn gustatory system can be damaged, in- terfering with the basic sensory and hedonic proc- esses to different tastants. Fasting during the prenatal period and for 24 days postnatally results in signifi- cant reductions of body and brain weight, number of branches, dendritic density, and cross-sectional area of the PBN multipolar neurons in the central lateral and central medial subnucleus particularly at post- natal days 20 and 30. Furthermore, the underfeeding paradigm affected more the middle portions of the dendritic tree than other parts of the neurons possibly disturbing the afferent characteristics of neuronal acti- vity propagation that may partly disrupt the elabora- tion of synaptic plasticity at later ages. These findings may play a role in the development of complex physio- logical phenomena such as food intake, taste discrimi- nation, learning taste aversion, and appetitive beha- vior.

关键词： Parabrachial Neurons Development Brainstem undernutrition Rats

Prevalence of undernutrition among Children Aged 6 - 59 Months in the Municipality of Toucountouna (Benin) in 2017

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Open Journal of Pediatrics 2023年第5期13卷 641-648页

作者： Alphonse Noudamadjo Falilatou Agbeille Mohamed Mèdétinmè Gérard Kpanidja Myriam Anita Dogo Gado Tchando Julien Didier Adédémy Joseph Agossou Faculty of Medicine Mother and Child Department University of Parakou Parakou Benin Saint Jean de Dieu District General Hospital of Tanguieta Tanguieta Benin National Training School of Higher Technicians in Public Health and Epidemiological Surveillance (ENATSE) University of Parakou Parakou Benin

Introduction: undernutrition is a public health problem in the world and especially in developing countries. According to the demographic and health survey with multiple indicators of Benin IV (DHS-MICS-IV), the prevalence of acute undernutrition (AU), chronic undernutrition (CU) and that of underweight (UW) was 16%, 45% and 21%, respectively. The objective of this work was to determine the prevalence of undernutrition in children aged 6 to 59 months in the municipality of Toucountouna in 2017. Materials and Methods: This was a descriptive cross-sectional study with two-stage cluster random sampling, composed of 390 children aged 6 to 59 months, living in the municipality of Toucountouna for at least six months. The study variables were: socio-demographic, economic, behavioral, socio-sanitary and anthropometric. Data were entered and analyzed using Epi-info 7.2 software. Results: 203 out of 390 children included, were boys (sex ratio of 1.08). The mean age of the children was 28.70 ± 11.79 months. The prevalence of AU, CU and UW was 10.26%, 31.54% and 11.79%, respectively. Conclusion: The results of this study showed that efforts remain to be made in terms of undernutrition and other surveys could identify the determinants linked to this situation in the locality for the effective implementation of prevention.

关键词： Prevalence undernutrition Children Benin

Magnitude and Determinants of undernutrition among Pregnant Women Attending a Public Hospital in Kenya

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Open Journal of Obstetrics and Gynecology 2022年第6期12卷 541-561页

作者： Okubatsion Tekeste Okube Margaret Wanjiku Weldemichael Andemariam School of Nursing The Catholic University of Eastern Africa Nairobi Kenya Department of Surgery University of Nairobi Nairobi Kenya

Background: undernutrition during pregnancy in the developing countries is a major public health problem due to its strong association with maternal and child morbidity and mortality. The available data on the extent and determinants of under-nutrition among pregnant women in Kenya is scant. This main objective of the study is to establish the extent and determinants of undernutrition in pregnant women attending a public hospital in Kenya. Methods: A cross-sectional study was conducted among 162 randomly selected pregnant women who attended antenatal clinic at Pumwani Maternity Hospital, a well-known public health facility in Nairobi. A semi-structured questionnaire was used to collect the data. Nutritional status of the pregnant mothers was determined using mid-upper arm circumference measurement. Hemoglobin level was extracted from the maternal antenatal card to determine their anemic status. Descriptive and inferential analyses were done using SPSS Software (version 22.0). Frequencies and proportions were generated for categorical variables. While mean and standard deviation were computed for continuous variables. The chi-square test of independence was employed to establish the relationship between the independent variables and dependent variable. Multivariable logistic regression analysis was used to identify the variables independently linked to maternal undernutrition. Results: The overall prevalence of undernutrition and anemia among the pregnant women was 27% and 39.7%, respectively. Multivariable logistic analysis showed that being single [AOR = 4.27;95% CI = 2.21 - 8.32, P = 0.001], divorced/separated [AOR = 2.25;95% CI = 1.13 - 4.87;P = 0.021], self-employed [AOR = 4.27;95% CI = 2.21 - 8.32;P = 0.022], illiterate [AOR = 4.31;95% CI = 2.55 - 8.20;P = 0.007), having short birth interval (<24 months) [AOR = 2.54;95% CI = 1.43 - 5.53;P = 0.042] and being anemic [AOR = 2.7;95% CI = 1.66 - 4.97;P = 0.037] were the variables significantly and independently asso

关键词： Anemia Determinants Kenya Prevalence Pregnant Women undernutrition

Effects of Perinatal undernutrition and Massage Stimulation upon the Ambiguus Nucleus in the Rat Prior to Weaning

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Journal of Behavioral and Brain Science 2013年第2期3卷 200-209页

作者： Dora Lopez-Jimenez Carmen Torrero Mirelta Regalado Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico Department of Developmental Neurobiology and Neurophysiology Institute of NeurobiologyNational Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

undernutrition produces morphological brain alterations and cognitive deficiencies in children of underdeveloped countries. The central nervous system (CNS) alterations mainly interfere with the anatomical organization of areas undergoing a phase of intense postnatal cell proliferation, disrupting plastic processes like learning, memory, and phonation. In the rat pup, prenatal malnutrition interferes with the elaboration of ultrasonic vocalizations (USVs) by poorly understood mechanisms. The neuronal caudal portion of the nucleus ambiguus (Ambc) innervates the laryngeal intrinsic muscles to produce phonation, a basic USV communication system. During postnatal development, enhanced plasticity phenomena play a fundamental role in improving brain function. Thus, the massage stimulation (MS) may accelerate growth and induce neurogenesis in different areas of the brain. The current study analyzed the effects of a daily 10-min MS on the dendritic tree and perikarya measurements of Ambc multipolar motoneurons (Golgi-Cox) of perinatally underfed (U), control (C), control massage-stimulated (CMS), and underfed massage-stimulated (UMS) groups at postnatal days (PDs) 8, 12, and 15. The data indicated that the dendritic scores were reduced (p undernutrition.

关键词： Nucleus Ambiguus Development Massage Stimulation Perinatal undernutrition Rat Pups

Focus on undernutrition in Care Homes： A Retrospective Service Evaluation

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Journal of Food Science and Engineering 2018年第4期8卷 143-170页

作者： Rachael Masters Bishop Auckland Hospital Cockton Hill Road Bishop Auckland DL14 England

“Let them eat cake”： a retrospective service evaluation of Focus on undernutrition in care homes. Introduction： undernutrition is a major cause and consequence of poor health in older people, affecting 35% of residents in care homes. Focus on undernutrition （FoU）, a dietetic service delivered by dietetic assistants uses a multifaceted approach to undernutrition management. This study aims to evaluate FoU’s impact on undernutrition outcome measures in care homes; including FoU’s influence on weight change in residents “at risk” of undernutrition, and prevalence of undernutrition and pressure ulcers （PU）. Methods： A retrospective pragmatic service evaluation was undertaken using pseudonymised data collected over 13 years on weight, undernutrition risk and PU from long-stay residents’ notes before and six months after training （FoU）. Results： Analysis completed on 104 homes, 4,315 residents （71.3% female; mean stay 10.8 （1-278） months） in County Durham. Following FoU a significant difference was identified for： improved rate of weight change for “at risk” residents （p 〈 0.001）. undernutrition risk significantly influenced weight change （low： B1.04 kg, E0.01 kg; moderate： B-1.79 kg, E-0.38 kg; high： B-0.83kg, E1.00 kg, Bp 〈 0.001, Ep = 0.001）. Reduced undernutrition prevalence （p 〈 0.001） from 32.7% to 29.1% residents “at risk” of undernutrition （moderate： B13.1%, E8.9%; high： B19.6%, E15.9%）. Nutrition screening significantly improved （B76.3%, E98.7%, p 〈 0.001）, reduced prevalence PU （51%, p 〈 0.001）. PU prevalence significantly increased with undernutrition severity at baseline （p 〈 0.001）, but not following FoU （p = 0.233）（low： B5%, E2.3%; moderate： B6.9%, E1.6%; high： B10.5%, E3.9%）. Odds of developing PU reduced 53% （OR： 0.47）. B：baseline; E：evaluation; OR： odds ratio. Conclusion： These results demonstrate dietetic assistants delivering FoU significantly improves weight, undernutrition and PU prevalence in care homes. Indicating FoU is an effective model

关键词： “MUST”/“malnutrition universal screening tool” care homes older people undernutrition malnutrition training food first nutrition screening tool.