检索结果-南通市图书馆

transsphenoidal surgery for prolactinomas in male patients:a retrospective study

Asian Journal of Andrology 2023年第1期25卷 113-118页

作者： Wei-Jie Su Hong-Cai Cai Guo-Chen Yang Ke-Jun He Hong-Lin Wu Yi-Bing Yang Hong-Xing Tang Li-Xuan Yang Chun-Hua Deng Neurosurgery Unit The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Department of Urology The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China

Male patients with prolactinomas usually present with typical hyperprolactinemia symptoms,including sexual dysfunction and ***,clinical factors related to sexual dysfunction and surgical outcomes in these patients remain *** study aimed to investigate the outcomes of male patients with prolactinomas after transsphenoidal surgery and the risk factors affecting sexual *** study was conducted on 58 male patients who underwent transsphenoidal surgery for prolactinomas between May 2014 and December 2020 at the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,*** evaluated the sexual function of patients before and after surgery through International Index of Erectile Function-5 scores,libido,and frequency of morning *** the 58 patients,48(82.8%)patients had sexual intercourse *** those 48 patients,41(85.4%)patients presented with erectile *** preoperative International Index of Erectile Function-5 scores in patients with macroprolactinomas were significantly higher than those in patients with giant prolactinomas(17.63±0.91 vs 13.28±1.43;P=0.01).Postoperatively,the incidence of erectile dysfunction was 47.9%,which was significantly lower than that preoperatively(85.4%;P=0.01).Twenty-eight(68.3%)patients demonstrated an improvement in erectile *** size and invasiveness were significantly correlated with the improvement of erectile *** testosterone<2.3 ng ml^(-1)was an independent predictor of improvement in erectile *** conclusion,our results indicated that tumor size and invasiveness were important factors affecting the improvement of sexual dysfunction in male patients with *** preoperative testosterone level was an independent predictor related to the improvement of erectile dysfunction.

关键词： erectile dysfunction prolactinomas sexual dysfunction transsphenoidal surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

RECONSTRUCTION OF THE SELLAR FLOOR FOLLOWING transsphenoidal surgery USING GELATIN FOAM AND FIBRIN GLUE

引用

Chinese Medical Sciences Journal 2005年第3期20卷 198-201页

作者： Jian Yin Chang-bao Su Zhi-qin Xu Xue-wei Xia Fei Song Department of Neurosurgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Department of Neurosurgery the Second Affiliated Hospital Dalian Medical University Dalian 116027

Objective To introduce a new principle of sellar reconstruction and to evaluate the effectiveness of absorbable gelatin foam and fibrin glue for sellar reconstruction. Methods A total of 176 consecutive patients who underwent surgery for pituitary adenomas, cysts, chordomas, or subdiaphragmatic craniopharyngiomas in the sella turcica between January 2001 and April 2003 at Peking Union Medical College Hospital were enrolled. Different techniques of sellar closure and indications for each specific condition were retrospectively reviewed. Results Seventy-seven (43.7%) patients developed a visible cerebrospinal fluid (CSF) leakage during surgery. Intra- operative CSF leakage were repaired simply with gelatin foam and fibrin glue in 62 (35.2%) patients, and with autologous fat graft and sellar floor reconstruction in 15 (8.5%) patients. Postoperative CSF rhinorrhea occurred only in 1 case. There were no visual deterioration, allergic rhinitis, meningitis, pneumocranium, granulomas, or other complications asso- ciated with the reconstruction procedure. Conclusion The procedure of using gelatin foam and fibrin glue and principle of cranial base reconstruction is safe and effective in preventing postoperative complications following transsphenoidal surgery.

关键词： transsphenoidal surgery sellar floor reconstruction cerebrospinal fluid leakage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

EFFECT OF PREOPERATIVE USE OF LONG-ACTING OCTREOTIDE ON GROWTH HORMONE SECRETING PITUITARY ADENOMA AND transsphenoidal surgery

引用

Chinese Medical Sciences Journal 2005年第1期20卷 23-26,页

作者： JianYin Chang-baoSu Zhi-qinXu YiYang Wen-binMa WeiTao ZhongYang Xue-weiXia DepartmentofNeurosurgery PekingUnionMedicalCollegeHospitalChineseAcademyofMedicalSciences＆PekingUnionMedicalCollegeBeijing100730

Objective To investigate whether somatostatin analog octreotide long acting release (LAR) shrinks growth hormone (GH) secreting adenomas, and improves the results of subsequent transsphenoidal surgery. Methods Seventeen previously untreated active acromegalic patients with pituitary adenomas were treated with LAR (30 mg intramuscular injection every 28 days) for 3 months prior to transsphenoidal surgery. Clinical reaction, mean GH secretion, and tumor volume were measured under basal conditions and after LAR treatment. Results Presurgical treatment improved acromegaly symptoms and induced a significant reduction of GH under the 5 ng/mL limit in microadenoma (P 25%) occurred in the macroadenoma group. Statistical analysis showed tumor shrinkage caused by LAR was greater in macroadenoma group than that in microadenoma group (P < 0.05). During operation, adenoma was soft in 15 cases, with the exception of 2 cases in which the soft tumor was divided by fibrous septa, but all tumor removal was smooth. Conclusions A short term administration of preoperative LAR may induce a significant decrease in GH-secretion level and adenoma volume. Presurgical use of octreotide LAR improves surgical results especially in macroadenomas.

关键词： pituitary adenoma somatostatin analog transsphenoidal surgery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

transsphenoidal surgery for pituitary adenoma in elderly patients

Transsphenoidal surgery for pituitary adenoma in elderly pat...

引用

2009年浙江省神经外科学术年会

作者： Department of Neurosurgery The First Hospital of Hangzhou Hangzhou(310006) China Hui Guozhen Department of Neurosurgery The First Affliated Hospital of Suzhou University Yu Wenhua Xu Peiyuan Zhu Qiang Che Zhihao

Purpose To evaluate the presentation and perioperative risk associated with transsphenoidal surgery in patients over the age of ***.A retrospective chart review was undertaken for patients over the age of 65 undergoing transsphenoidal surgery between 2003 and ***-four patients over the age of 65 were identified with an average age of 70.4 years(range 65-84).The average follow-up period was 44 months(range 14- 104).Symptoms of mass effect were the presenting complaint in 72%of patients while 9%had documentation of growth on imaging *** percent presented with a history consistent with *** patients (5%) presented with ***-operative hospital stay averaged 2.6 days(range 2-7).Eight patients had new hormonal deficits post-operatively(1ACTH,3 TSH,2 ACTH/TSH,2 vasopressin).There were no cardiopulmonary complications and no deaths within 90 days of *** surgery can be performed in patients over the age of 65 without undo significant *** removal of pituitary adenomas should be considered the mainstay of treatment in elderly patients in whom treatment is *** who are medically suitable candidates should be offered surgical resection as would their younger counterparts.

关键词： Elderly pituitary adenoma transsphenoidal surgery

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Complications of transsphenoidal surgery for sellar region： intracranial vessel injury

引用

Chinese Medical Journal 2009年第10期122卷 1154-1156页

作者： ZHOU Wei-guo YANG Zhan-quan Department ol Otolaryngology Head and Neck surgery Beljmg Tongren Hospital Capital Medical University Key Laboratory of Otolaryngology Head and Neck surgery (Capital Medical University) Ministry of Education Beijing 100730 China Department of Otolaryngology Head and Neck surgery China-Japan Union Hospital Jilin University Changchun Jilin 130041 China

Background Intracranial vessel injury is a severe complication of transsphenoidal surgery （TSS） for lesions of sellar region. The purpose of this study was to improve recognition of the complication. Methods The clinical data of 400 cases of TSS for sellar region from 1964 to 2004 were reviewed retrospectively. Ten patients with complications of intracranial vessel injury were included in this study, 7 underwent transsphenoidal microsurgery and 3 underwent endoscopic TSS. Subarachnoid hemorrhage （SAH） occurred in 8 cases, hemorrhage of cavernous sinus in one, and post-operative cerebral hemorrhagic infarction caused by thrombosis of injured right internal carotid artery in one. The clinical data of all the patients were analyzed. Results The SAH resulted from hemorrhage of residues of tumor in 2 patients and from damaged sellar and arachnoidea in 6 patients. The cause of hemorrhage of anterior intercavernous sinus was malformation of anterior intercavernous sinus. The reason of thrombus of internal carotid artery was manipulation of operation. Three patients died and six patients were cured. One patient lived with hemiplegia. Conclusions The cause of intracranial vessels injury of TSS is complicated. Detailed anatomic knowledge of seller and skilled operation is helpful to reduce the complication.

关键词： transsphenoidal surgery subarachnoid hemorrhage complication pituitary adenoma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Transnasal-transsphenoidal surgery with recent advancement of radiological diagnosis for Cushing diseases

Transnasal-transsphenoidal surgery with recent advancement o...

引用

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Takumi Abe Daisuke Tanioka Department of Neurosurgery Showa University School of Medicine

ACTH-secreting pituitary adenoma（Cushing’s disease） is relatively rare *** diagnosis and surgical treatment are most difficult among the pituitary *** first choice of treatment for Cushing’s disease is tumor extirpation via transsphenoidal *** difficult points in surgical treatment for Cushing’s disease were described *** first is existence of a tiny tumor which cannot be detected on *** detect a tiny adenoma,T1-weighted coronal,sagittal,and axial images with enhancement on MRI are ***-secreting adenoma exists at lateral area in the pituitary in most *** detect an adenoma which exists at border of the pituitary,3.0Tesla MRI is so *** second is existence of double adenomas such as a case with both a large nonfunctioning pituitary adenoma on MRI and a tiny ACTH-secreting adenoma without detection on *** such a case,even if a large adenoma has been totally removed,Cushing’s disease is not *** judge whether a tumor with detection on MRI is ACTH-secreting adenoma,cavernous sinus ACTH sampling,developed by *** in Japan,is ***,cavernous sinus ACTH sampling is not effective for a case with existence of the tumor at central area in the *** best surgical indication for Cushing’s disease is detection of tumor on MRI and identification of ACTH secretion of its tumor by cavernous sinus ACTH ***’s disease recurs with high *** most important surgical point of tumor removal for Cushing’s disease is to remove totally including tumor capsule and a part of normal gland at the border,even if transient hypopituitarism after surgery will be *** surgical method is called extra-capsule tumor *** criterion of total tumor removal is that serum ACTH and cortisol are less than normal range one day morning after *** surgery for Cushing’s disease should be performed by pituitary *** pathological diagnosis is ***-secreting pituitary

关键词： Cushing’s disease cavernous sinus ACTH sampling 3.0tesla MRI transsphenoidal surgery

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Monitoring and analysis of prevention and treatment of intracranial infection during perioperative period of endoscopic transsphenoidal surgery

Monitoring and analysis of prevention and treatment of intra...

引用

第十五届中国医师协会神经外科医师年会

作者： Xiaofeng Wang Lijun Heng Weinan Central Hospital Tangdu Hospital Air Force Medical University

Objective:to summarize and analyze the prevention and control methods of intracranial infection in perioperative period of endoscopic transsphenoidal surgery,especially through the diagnosis and treatment of intracranial infection cases,and summarize how to better avoid,diagnose,treat and monitor intracranial *** the same time,attention should be paid to the evaluation of infection monitoring indicators of intracranial infection and related ***:the cases of intracranial infection after transsphenoidal surgery in Tangdu Hospital during 2018 were analyzed,and the prevention and control methods of infection before,during and after operation were summarized and *** the same time,its effectiveness was evaluated and ***:the incidence of intracranial infection after transsphenoidal surgery was basically consistent with that reported in the *** the same time,it was analyzed that intracranial infection was easy to occur under the conditions of long operation time,improper cleaning of nasal hair before operation,more bleeding in China and intracranial gas accumulation after *** and treatment of lumbar cistern drainage tube is not recommended after infection,but it is suggested that lumbar puncture and cerebrospinal fluid release should be performed daily and routine,biochemical and culture should be carried *** the same time,attention should be paid to the monitoring of blood routine and blood glucose at the same time,and the therapeutic effect of anti-infection should be monitored and *** the same time,antibiotics were treated according to the results of drug sensitivity ***:continuous monitoring of blood routine,white blood cells and neutrophils should be paid attention to in patients with postoperative hyperthermia,lumbar puncture test should be performed in time,cerebrospinal fluid should be cultured and diagnosed clearly,and broad-spectrum antibiotics should be used empirically

关键词： transsphenoidal surgery intracranial infection prevention and treatment strategy

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

The Use of Neuronavigation with Vasular Microdoppler in transsphenoidal Pituitary surgery

引用

Open Journal of Modern Neurosurgery 2016年第1期6卷 45-50页

作者： Mehmet Hakan Seyithanoglu Serkan Kitis Meliha Gundag Papaker Fatih Calis Tolga Turan Dundar Serdar Cevik Department of Neurosurgery Bezmialem Vakif University Faculty of Medicine Istanbul Turkey Department of Neurosurgery Agri State Hospital Agri Turkey

Object: To evaluate the use of neuronavigation with vascular micro-doppler in transsphenoidal pituitary surgery. Methods: 141 cases having done transsphenoidal pituitary surgery are evaluated from 2005 to 2014. Fluoroscopy was used in 69 cases and vascular micro-doppler with neuronavigation were used in 72 cases. Results: transsphenoidal surgery has a lot of risks due to sella’s deep location, and position of the carotid artery and the optic nerve. Clasically the fluoroscopy and microscopic anatomical markers were used in order to minimize the risk of carotid artery and optic nerve damage. Additional devices such as neuronavigation and vascular micro-doppler are needed to decrease the morbidity and mortality arising from these injuries. Conclusion: Neurovascular complications such as carotid artery and optic nerve injuries owing to disorientation in transsphenoidal surgery will reduce the use of neuronavigation with vascular micro-doppler.

关键词： transsphenoidal surgery Vascular Micro-Doppler Neuronavigation Pituitary Adenomas

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bilateral inferior petrosal sinus sampling for the treatment of Cushing's disease Data from 52 cases from one institute over an eight-year period

引用

Neural Regeneration Research 2011年第28期6卷 2203-2210页

作者： Changyan Fan Xiuhua Shi Qingfang Sun Liuguan Bian Weiguo Zhao Jiankang Shen Hua Zhang Tingwei Su Weiqing Wang Xiaoying Li Guang Ning Liang Kong Lingling Hu Department of Neurology Wuxi No. 3 People＇s Hospital Wuxi 241043 Jiangsu Province China Department of Neurosurgery Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Radiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Endocrine and Metabolism Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China

The present study analyzed data from 108 Cushing＇s disease patients, who underwent transsphenoidal surgery in one hospital between January 2003 and April 2010, to investigate the performance value of bilateral inferior petrosal sinus sampling （BIPSS）. Of the 108 patients 52 underwent BIPSS prior to surgery and 56 did not. Results showed that BIPSS accuracy for the diagnosis of Cushing＇s disease was 86.5% （45/52）, and accuracy for adenoma lateralization during surgery was 76.9% （40/52）. In addition, early remission rate was significantly greater compared to patients without BIPSS. Results demonstrated that BIPSS facilitated localization and diagnosis of Cushing＇s disease and helped to predict adenoma lateralization.

关键词： bilateral inferior petrosal sinus Cushing's disease Cushing's syndrome pituitary adenoma transsphenoidal surgery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Functioning gonadotroph adenoma with hyperestrogenemia and ovarian hyperstimulation in a reproductive-aged woman:A case report and review of literature

引用

World Journal of Clinical Cases 2023年第6期11卷 1341-1348页

作者： Ying He Yu-Tao Gao Li Sun Department of Gynecological Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeShenzhen 518116Guangdong ProvinceChina Department of Gynecological Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Functioning gonadotroph adenomas are extremely rare pituitary tumors that secrete gonadotropins and exhibit distinct clinical ***,we report a case of functioning gonadotroph adenoma in a reproductive-aged woman and discuss its diagnosis and *** SUMMARY A 21-year-old female patient with abdominal pain,irregular menstruation,hyperestrogenemia,and an ovarian mass was *** magnetic resonance imaging(MRI)revealed a pituitary macroadenoma,and transsphenoidal surgery relieved her clinical *** transsphenoidal surgery,plasma CA125,estradiol levels were elevated,while prolactin,luteinizing hormone,follicle-stimulating hormone,PROG,cortisol,FT4,thyroid-stimulating hormone,para-thyroid hormone,and GH levels were maintained at normal *** trans-sphenoidal surgery,the patient was diagnosed with a functioning gonadotroph *** follow-up,pelvic ultrasound confirmed normal-sized ovaries in the patient,the menstrual cycle returned to regular,and her hormones were maintained within a normal *** was no evidence of tumor recurrence after two years of *** Early diagnosis of functioning gonadotroph adenomas should be considered in patients with hyperestrogenism,irregular menstruation,large or recurrent ovarian cysts,and visual field *** MRI should be performed,and transsphenoidal surgery is recommended for the management of this disease.

关键词： Functional gonadotroph adenoma Ovarian hyperstimulation Hyperestrogenemia transsphenoidal surgery Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：