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Postoperative pain due to an occult spinal infection:A case report

World Journal of Clinical Cases 2021年第15期9卷 3637-3643页

作者： Michiel Frederik Vande Kerckhove Vincent Fiere Thais Dutra Vieira Sami Bahroun Marc Szadkowski Henrid'Astorg Centre Orthopédique Santy Hopital PrivéJean MermozRamsay-Générale de SantéLyonFrance

BACKGROUND A high degree of vigilance is warranted for a spinal infection,particularly in a patient who has undergone an invasive procedure such as a spinal *** average delay in diagnosing a spinal infection is 2-4 *** our patient,the diagnosis of a spinal infection was delayed by 1.5 *** SUMMARY A 60-year-old male patient with a 1-year history of right-sided lumbar radicular pain failed conservative *** weeks to prior to surgery he received a spinal injection,which was followed by increasing lumbar radicular pain,weight loss and *** went unnoticed and surgery took place with right-sided L4-L5 combined microdiscectomy and foraminotomy via a posterior *** day after surgery,the patient developed left-sided lumbar radicular *** cultures grew Staphylococcus aureus(***).Magnetic resonance imaging showed inflammatory aberrations,revealing septic arthritis of the left-sided L4/L5 facet joint as the probable *** surgery took place and *** was isolated from bacteriological *** patient received postoperative antibiotic treatment,which completely eradicated the *** The development of postoperative lower back pain and/or lumbar radicular pain can be a sign of a spinal infection.A thorough clinical and laboratory work-up is essential in the preoperative evaluation of patients with spinal pain.

关键词： Arthritis Septic Lumbar region Disc herniated spinal injections Case report

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Effects of intrathecal NMDA and AMPA receptors agonists or antagonists on antinociception of propofol

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Acta Pharmacologica Sinica 2004年第1期 11-16页

作者： Ai-jun XU, Shi-ming DUAN, Yin-ming ZENGJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical College, Xuzhou 221002, China

AIM: To study the effects of intrathecal (it) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors and NMDAR1 antisense oligodeoxynucleotides (AS ODN) on the antinociception of propofol. METHODS: Hot-plate test (HPPT) and acetic acid-induced writhing test were used to measure the nociceptive thresholds in mice. The effects of intrathecal NMDA,

关键词： N-methyl-D-aspartate receptors AMPA receptors spinal injections antinociception propofol

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