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Driving forces of continuing evolution of rotaviruses

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World Journal of Virology 2024年第2期13卷 58-70页

作者： Mohamad Saifudin Hakim Faris Muhammad Gazali Suci Ardini Widyaningsih Mohammad Khalid Parvez Postgraduate School of Molecular Medicine Erasmus MC-University Medical CenterRotterdam 3015GDNetherlands Viral Infection Working Group International Society of Antimicrobial ChemotherapyLondon EC4R 9ANUnited Kingdom Master Program in Biotechnology Postgraduate SchoolUniversitas Gadjah MadaYogyakarta55281Indonesia Master of Medical Sciences in Clinical Investigation Harvard Medical SchoolBostonMA 02115United States Department of Pharmacognosy College of PharmacyKing Saud UniversityRiyadh11451Saudi Arabia

Rotaviruses are non-enveloped double-stranded RNA virus that causes acute diarrheal diseases in children(<5 years).More than 90%of the global rotavirus infection in humans was caused by Rotavirus group *** infection h... 详细信息

Rotaviruses are non-enveloped double-stranded RNA virus that causes acute diarrheal diseases in children(reassortment mechanism,either in the intra-or the ***,other factors are also known to have an impact on rotavirus *** review discusses the structure and types,epidemiology,and evolution of *** article also reviews other supplemental factors of rotavirus evolution,such as genetic reassortment,mutation rate,glycan specificity,vaccine introduction,the host immune respo-nses,and antiviral drugs.

关键词： Rotavirus Epidemiology Evolution reassortment Vaccine

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

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Avian Research 2019年第4期10卷 507-516页

作者： Ali M.Zanaty Ahmed M.Erfan Wessam H.Mady Fatma Amer Ahmed A.Nour Neveen Rabie Mohamed Samy Abdullah A.Selim Wafaa M.M.Hassan Mahmoud M.Naguib National Laboratory for Veterinary Quality Control on Poultry Production Animal Health Research InstituteGiza 12618Egypt Zoonosis Science Centre Department of Medical Biochemistry and MicrobiologyUppsala University75123 UppsalaSweden

Background:Avian influenza viruses(AIVs)have been identified from more than 100 different species of wild birds around the *** migratory birds can act as potential spreaders for AIVs to domestic birds between different *** is situated on important migratory flyways for wild birds between different *** much is known about circulation of zoonotic potential H5N1 and H9N2 AIVs in domestic poultry in Egypt,little is known about the pivotal role of migratory birds in the maintenance and transmission of the viruses in ***:Targeted AIV surveillance has been conducted in 2017 in different wetlands areas in Northern and Eastern ***:AIV of subtype H5 was detected in two bird *** addition,a novel reassortant strain of the H6N2 subtype was identified which reveals the continuous risk of new influenza virus(es)introduction into *** novel virus possesses a reassortant pattern originating from different AIV gene ***:Intervention control strategies should be performed to minimize the possible contact of domestic birds with wild birds to lower the risk of virus transmission at this *** addition,constant monitoring of AIVs in migratory birds is essential in the early detection of influenza virus introduction into Egypt.

关键词： Avian in fluenza virus H6N2 Egypt reassortment Wild birds

Clinical characteristics of human infection with a novel avian-origin influenza A（H10N8） virus

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Chinese Medical Journal 2014年第18期127卷 3238-3242页

作者： Zhang Wei Wan Jianguo Qian Kejian Liu Xiaoqing Xiao Zuke Sun Jian Zeng Zhenguo Wang Qi Zhang Jinxiang Jiang Guanghui Nie Cheng Jiang Rong Ding Chengzhi Li Ran Horby Peter Gao Zhancheng Nanchang University First Affiliated Hospital Nanchang Jiangxi 330006 China Nanchang First Hospital Nanchang Jiangxi 330008 China Jiangxi Province Center for Disease Control and Prevention Nanchang Jiangxi 330038 China Jiangxi Provincial People's Hospital Nanchang Jiangxi 330006China Nanchang University Fourth Affiliated Hospital Nanchang Jiangxi 330003 China Chinese Center for Disease Control and Prevention Beijing 102206China Department of Respiratory and Critical Care Medicine PekingUniversity People's Hospital Beijing 100044 China Oxford University Clinical Research Unit -Wellcome Trust MajorOverseas Programme Hanoi Viemam

Background Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A （H10N8） virus which can infect humans and cause severe diseases. Methods Collecting clinical data of three cases of human infection with a novel reassortment avian influenza A （H10N8） virus in Nanchang, Jiangxi Province, China. Results Three cases of human infection with a new reassortment avian influenza A（H10N8） virus were described, of which two were fatal cases, and one was severe case. These cases presented with severe pneumonia that progressed to acute respiratory distress syndrome （ARDS） and intractable respiratory failure. Conclusion This novel reassortment avian influenza A （H10N8） virus in China resulted in fatal human infections, and should be added to concerns in clinical practice.

关键词： human infection avian influenza A(H10N8) virus reassortment clinical characteristics

Is China an influenza epicentre?

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Chinese Medical Journal 1997年第8期110卷 61-65页

作者： KennedyF.Shortridge Department of Microbiology the University of Hong Kong University Pathology Building Queen Mary Hospital Hong Kong China

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ＩｓＣｈｉｎａａｎｉｎｆｌｕｅｎｚａｅｐｉｃｅｎｔｒｅ？ＫｅｎｎｅｄｙＦ．ＳｈｏｒｔｒｉｄｇｅＤｅｐａｒｔｍｅｎｔｏｆＭｉｃｒｏｂｉｏｌｏｇｙ，ｔｈｅＵｎｉｖｅｒｓｉｔｙｏｆＨｏｎｇＫｏｎｇ，ＵｎｉｖｅｒｓｉｔｙＰａｔｈｏｌｏｇｙＢｕｉｌｄｉｎｇ，Ｑ...

关键词： A VIRUSES SOUTHERN CHINA HONG-KONG PIGS TRANSMISSION reassortment