检索结果-南通市图书馆

Clinical application of reserved gastric tube in neuroendoscopic endonasal surgery for pituitary tumor

World Journal of Clinical Oncology 2024年第3期15卷 411-418页

作者： Xi Chen Long-Yao Zhang Zhi-Feng Wang Yi Zhang Yu-Hua Yin Xue-Jian Wang Department of Nursing Affiliated Hospital 2 of Nantong UniversityNantong 226000Jiangsu ProvinceChina Department of Neurosurgery Affiliated Hospital 2 of Nantong UniversityNantong 226000Jiangsu ProvinceChina Department of Neurosurgery Renji HospitalShanghai Jiao Tong UniversityShanghai 226000China

BACKGROUND The neuroendoscopic approach has the advantages of a clear operative field,convenient tumor removal,and less damage,and is the development direction of modern neurosurgery.At present,transnasal surgery for sphenoidal pituitary tumor is widely used.But it has been found in clinical practice that some patients with this type of surgery may experience post-operative nausea and vomiting and other discomforts.AIM To explore the effect of reserved gastric tube application in the neuroendoscopic endonasal resection of pituitary tumors.METHODS A total of 60 patients who underwent pituitary adenoma resection via the endoscopic endonasal approach were selected and randomly divided into the experimental and control groups,with 30 in each group.Experimental group:After anesthesia,a gastric tube was placed through the mouth under direct vision using a visual laryngoscope,and the fluid accumulated in the oropharynx was suctioned intermittently with low negative pressure throughout the whole process after nasal disinfection,during the operation,and when the patient recovered from anesthesia.Control group:Given the routine intraoperative care,no gastric tube was left.The number of cases of nausea/vomiting/aspiration within 24 h post-operation was counted and compared between the two groups;the scores of pharyngalgia after waking up,6 h post-operation,and 24 h postoperation.The frequency of postoperative cerebrospinal fluid leakage and intracranial infection were compared.The hospitalization days of the two groups were statistically compared.RESULTS The times of postoperative nausea and vomiting in the experimental group were lower than that in the control group,and the difference in the incidence of nausea was statistically significant(P<0.05).After the patient woke up,the scores of sore throat 6 h after the operation and 24 h after operation were lower than those in the control group,and the difference was statistically significant(P<0.05).The number of cases of postoperative cerebrospinal fluid leakage and intracran

关键词： Neuroendoscopy Endonasal approach pituitary tumor Reserved gastric tube Nausea Vomiting Aspiration Complications

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predictive value of pituitary tumor morphology on outcomes and complications in endoscopic transsphenoidal surgery

引用

World Journal of Otorhinolaryngology-Head and Neck Surgery 2022年第4期8卷 321-329页

作者： Andrew T.Heffernan Joseph K.Han John Campbell James Reese William G.Day Joshua Edwards Ran V.Singh Wylie Zhu Kent K.Lam Department of Otolaryngology-Head and Neck Surgery Eastern Virginia Medical SchoolNorfolkVirginiaUSA Medical Center Radiologists NorfolkVirginiaUSA Department of Radiology Eastern Virginia Medical SchoolNorfolkVirginiaUSA Sentara Healthcare Analytics and Delivery Science Institute NorfolkVirginiaUSA Neurosurgical Associates NorfolkVirginiaUSA Sentara Neurosurgery Specialists NorfolkVirginiaUSA

Purpose:Endoscopic transsphenoidal surgery(ETSS)is an increasingly utilized approach for resection of pituitary tumors.Prior studies have evaluated preoperative tumor size,location,and extent as prognostic factors for surgical resection.There is little data on the relationship between preoperative pituitary tumor radiographic morphology and surgical outcomes.Study Design:Retrospective longitudinal study.Setting:Single tertiary care institution.Subjects and Methods:Preoperative magnetic resonance imaging and computed tomography scans from patients undergoing ETSS for pituitary tumor resections from 2007 to 2017 were retrospectively evaluated.A neuroradiologist classified these pituitary tumors into six morphologic groups,each defined by volume,dimensions,extension,and shape.Surgical difficulty,rates of incomplete resection,and postoperative complications were then stratified in relation to the morphologic groups.Results:pituitary tumors from 131 patients were classified from preoperative imaging into six characteristic morphologies:(1)microtumor,(2)round,(3)transverse oblong,(4)superior-inferior oblong,(5)bilobed,and(6)large lobulated.tumors that were characterized with the large lobulated,bilobed,and transverse oblong morphologies correlated with higher rates of postoperative evidence of residual tumor(70%,36%,and 47%,respectively,all Ppituitary tumors that can be determined from preoperative imaging.Different tumor morphologic groups are associated with varying degrees of gross tumor resection,complications,and surgical difficulty.Utilizing pituitary tumor morphology may aid surgeons in planning the extent of resection,need for complex closure,and patient counseling.

关键词： endoscopic transsphenoidal surgery morphology pituitary adenoma pituitary tumor surgical outcomes tumor shape

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Application and Care of Two Kinds of Sphenoid Sinus Packing Materials after pituitary tumor Resection with the Transnasal Endoscopic Approach

引用

Neuroscience & Medicine 2020年第4期11卷 130-141页

作者： Shuo Yang Qiyu Feng Huidan Zhu Zhihuan Zhou Ji Zhang Department of Neurosurgery State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Sun Yat-sen University Cancer Center Guangzhou China

Background: Neuroendoscopic transsphenoidal approach for resection of pituitary adenomas has the advantages of less damage, fewer complications, and a faster recovery than the traditional approach and has beening favored by neurosurgeons. However, there has no standard method of selecting suitable packing materials after the operation to relieve pain in patients and achieve the ideal hemostatic effect. We compared the postoperative complications and treatment effects of two different packing materials in patients with pituitary adenomas. Objective: To investigate the advantages and disadvantages of using a catheter balloon and iodoform gauze for hemostasis in patients undergoing pituitary tumor resection by neuroendoscopic transsphenoidal approach. Materials and Methods: We retrospectively analyzed these data of 48 cases treated with pituitary adenoma resection by the single nasal approach from January 2018 to October 2019 in Sun Yat-sen University Cancer Center. According to the type of sphenoid sinus packing material used, these patients were divided into balloon tamponade oppression group (24 cases) and tela iodoformum oppression group (24 cases), respectively. The balloon tamponade oppression group received catheter balloon tamponade oppression hemostasis, and the tela iodoformum oppression group underwent tela iodoformum oppression hemostasis. The outcomes and complications were compared between the two groups in which two kinds of sphenoid sinus packing materials were used for hemostasis after tumor resection by transnasal endoscopic approach. For the catheter balloon compression hemostasis method, on account of the plasticity of the balloon, the volume of water in the balloon can be adjusted according to the size of the patient’s own sphenoid cavity. The amount of bleeding and several complications in terms of discomfort during placement and removal of the packing material, rebleeding aft

关键词： Sphenoid Sinus Packing Material pituitary tumor Nursing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A systematic survey of LU domain-containing proteins reveals a novel human gene,LY6A,which encodes the candidate ortholog of mouse Ly-6A/Sca-1 and is aberrantly expressed in pituitary tumors

引用

Frontiers of Medicine 2023年第3期17卷 458-475页

作者： Dan Liu Chunhui Xu Yanting Liu Wen Ouyang Shaojian Lin Aining Xu Yuanliang Zhang Yinyin Xie Qiuhua Huang Weili Zhao Zhu Chen Lan Wang Saijuan Chen Jinyan Huang Zhe Bao Wu Xiaojian Sun Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Key Laboratory of Systems Biomedicine Ministry of EducationShanghai Center for Systems BiomedicineShanghai Jiao Tong UniversityShanghai 200240China CAS Key Laboratory of Tissue Microenvironment and tumor Shanghai Institute of Nutrition and HealthShanghai Institutes for Biological SciencesUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Department of Neurosurgery Center of Pituitary TumorRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Biomedical Big Data Center First Affiliated HospitalZhejiang University School of Medicineand Cancer CenterZhejiang UniversityHangzhou 310000China Department of Neurosurgery First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000China

The Ly-6 and uPAR(LU)domain-containing proteins represent a large family of cell-surface markers.In particular,mouse Ly-6A/Sca-1 is a widely used marker for various stem cells;however,its human ortholog is missing.In this study,based on a systematic survey and comparative genomic study of mouse and human LU domain-containing proteins,we identified a previously unannotated human gene encoding the candidate ortholog of mouse Ly-6A/Sca-1.This gene,hereby named LY6A,reversely overlaps with a lncRNA gene in the majority of exonic sequences.We found that LY6A is aberrantly expressed in pituitary tumors,but not in normal pituitary tissues,and may contribute to tumorigenesis.Similar to mouse Ly-6A/Sca-1,human LY6A is also upregulated by interferon,suggesting a conserved transcriptional regulatory mechanism between humans and mice.We cloned the full-length LY6A cDNA,whose encoded protein sequence,domain architecture,and exon‒intron structures are all well conserved with mouse Ly-6A/Sca-1.Ectopic expression of the LY6A protein in cells demonstrates that it acts the same as mouse Ly-6A/Sca-1 in their processing and glycosylphosphatidylinositol anchoring to the cell membrane.Collectively,these studies unveil a novel human gene encoding a candidate biomarker and provide an interesting model gene for studying gene regulatory and evolutionary mechanisms.

关键词： LU domain-containing protein family novel human gene LY6A pituitary tumor biomarker nonsynonymous SNP GPI-anchored protein

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carotid artery injury in endoscopic endonasal surgery: Risk factors, prevention, and management

引用

World Journal of Otorhinolaryngology-Head and Neck Surgery 2022年第1期8卷 54-60页

作者： Rahul K.Sharma Alexandria L.I race Jonathan B.Overdevest David A.Gudis Department of Otolaryngology-Head and Neck Surgery Columbia University Irving Medical CenterNewYork-Presbyterian HospitalNew YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery Vanderbilt University Medical CenterNashvilleTennesseeUSA

Objective:Endoscopic approaches for sinus and skull base surgery are increasing in popularity.The objective of this narrative review is to characterize risk factors for internal carotid artery injury in endoscopic endonasal surgery(EES),highlight preventative measures,and illustrate key management principles.Data Sources:Comprehensive literature review.Methods:Relevant literature was reviewed using PubMed/MEDLINE.Results:Carotid artery injury in EES is rare,with most studies reporting an incidence below 0.1%.Anatomic aberrancies,wide dissection margins,as well as specific provider and hospital factors,may increase the risk of injury.Multidisciplinary teams,comprehensive preoperative imaging,patient risk assessment,and formal training in vascular emergencies may reduce the risk.Management protocols should emphasize proper visualization of the injury site,fluid replacement,rapid packing,angiography,and endovascular techniques to achieve hemostasis.Conclusions:While EES is a relatively safe procedure,carotid artery injury is a devastating complication that warrants full consideration in surgical planning.Important preventative measures include identifying patients with notable risk factors and obtaining preoperative imaging.Multidisciplinary teams and management protocols are ultimately necessary to reduce morbidity and mortality.

关键词： carotid injury complications internal carotid pituitary pituitary adenoma pituitary tumor skull base surgery surgical outcomes transphenoidal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in the mechanism of action of metformin in pituitary tumors

引用

World Journal of Meta-Analysis 2023年第5期11卷 144-150页

作者： Long-Yao Zhang Yu-Hua Yin Xue-Jian Wang Department of Neurosurgery The Affiliated Hospital 2 to Nantong UniversityNantong 226000Jiangsu ProvinceChina Department of Neurosurgery Renji HospitalShanghai Jiao Tong UniversityShanghai 226000China

pituitary tumors are common intracranial tumors,but when faced with drugresistant or aggressive tumors,existing medical measures may not provide good control,leading to progression and deterioration.Metformin,a traditional hypoglycemic drug,has recently been discovered to have multiple functions including antitumor effects.There have been studies on the mechanism of metformin for the treatment of pituitary tumors,but it is uncertain whether it will provide new adjuvant or alternative therapies for the treatment of these tumors.We analyzed the potential mechanisms of action of metformin with respect to the inhibition of pituitary tumor growth and hormone secretion by reviewing the available literature.

关键词： Metformin pituitary tumor Mechanism Treatment Study Review

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

EXPRESSION OF EPIDERMAL GROWTH FACTOR, TRANSFORMINGGROWTH FACTOR-α AND THEIR RECEPTOR IN HUMAN pituitary tumorS

引用

Chinese Journal of Cancer Research 2001年第3期13卷 206-207页

作者：张龙雷霆薛德麟 Department of Neurosurgery Tongji Hospital Tongji Medical University Wuhan

Objective: To explore the role of growth factor autocrine stimulation in the pathogenesis of human pituitary tumors. Methods: The expression of EGF, TGF-( and EGFR were studied by immunohisto-chemical method on paraffin-embedded sections of 30 cases pituitary tumor. Results: EGFR and its ligands EGF, TGF-( expressed in majority of pituitary tumors. The expression of EGFR and its ligands varied with cells' intensity, density and type. Conclusion: The EGF autocrine stimulating exerted in the pituitary tumor development process, that tyrosine kinases inhibitors may be useful for pituitary tumors treatment.

关键词： pituitary tumor Epidermal growth factor Epidermal growth factor receptor Immunohisto-chemistry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical case discussions-Hypopituitarism and pituitary apoplexy caused by pituitary Adenomas

引用

Discussion of Clinical Cases 2015年第1期2卷 14-19页

作者： Gaisheng Tian Qinxue Li Dan Zhao Ying Wang Ruijing Yan Department of Geriatrics the Third Affiliated Hospital of Inner Mongolia Medical UniversityBaotouChina

A case of“Hypopituitarism and pituitary apoplex induced by pituitary Adenomas”was collected in the Third Affiliated Hospital of Inner Mongolia medical University Geriatric Department.A rare and atypical disease as it is,delayed diagnosis and treatment is easily seen among those cases.Therefore,the paper aims to investigate the difference of clinical characteristics and treatment outcome of pituitary adenomas in elder patient through the case analysis.Clinically,patients with pituitary dysfunction may have life-threatening crisis so that timely diagnosis and aggressive treatment can be effective in reducing the pituitary crisis and reducing the misdiagnosis rate.

关键词： pituitary tumor pituitary dysfunction pituitary apoplexy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intrasellar cavernous hemangioma: A case report and literature review

引用

Translational Neuroscience and Clinics 2017年第2期3卷 111-115页

作者： Xinmin Wu Hongquan Yu Gang Zhao Le Wang Yang Liu Yunqian Li Department of Neurosurgery the First Hospital of Jilin University Department of Ophthalmology the First Hospital of Jilin University Department of Radiology the First Hospital of Jilin University

Intrasellar cavernous hemangioma is rare. There are no specific symptoms and the mass effect often mimics pituitary macroadenoma. We present one case of intrasellar cavernous hemangioma that was misdiagnosed. Progressively decreasing vision was the main symptom in this case. The prolactin level was mildly increased but other biochemistry examinations were normal. Magnetic resonance imaging showed an enlarged pituitary fossa and an irregular solid tumor(33 mm × 22 mm × 22 mm) in the sella turcica and parasellar region. Subtotal removal in the case was performed through a transsphenoidal approach. Postoperatively, the patient's visual acuity improved. Through a literature review of 8 intrasellar cavernous hemangiomas, we found most lesions are likely to extend into the suprasellar cistern and cavernous sinus, and total resection is difficult. Transsphenoidal approach surgery should be applied for decompression of the optic nerve and biopsy, and stereotactic radiosurgery is preferable.

关键词： cavernous hemangioma sella turcica pituitary tumor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Long Noncoding RNA-H19 and pituitary Adenomas

The Long Noncoding RNA-H19 and Pituitary Adenomas

引用

第十六届中国医师协会神经外科医师年会

作者： Zerui Wu Zhipeng Su Zhe Bao Wu Department of Neurosurgery First Affiliated Hospital of Wenzhou Medical University

Objective:To investigate the role of H19 on pituitary adenomas and its underlying mechanism in vitro and in vivo..Methods:pituitary tumor tissues were obtained from pituitary tumor patients who underwent surgery between 2015 and 2020 at the Department of Neurosurgery,Ruijin Hospital of Shanghai Jiaotong University and Department of Neurosurgery,First Affiliated Hospital of Wenzhou Medical University;The Cell Counting Kit-8(CCK-8) assay was used to test cell viability;Real-time quantitative PCR was used to test the level of H19 and miR-93a;Western blot experiments were conducted to test the ATG7 expression level;Luciferase reporter assay and RNA immunoprecipitation were used to ensure the combination of H19 and miR-93a;Xenograft experiments were used to test the effect of H19 and miR-93a in vivo.Results:H19 inhibited tumor growth and had a synergistic effect with DA treatment on prolactinomas in vitro and in vivo.Mechanistically,H19 promoted ATG7 expression in pituitary tumor cells by inhibiting miR-93a expression.In addition,a potential binding site between miR-93 and H19 was confirmed,and low expression of miR-93 was previously found in DA-resistant prolactinomas.Furthermore,we showed that miR-93a regulates ATG7 expression by targeting ATG7 mRNA.Conclusion:Our study has identified the role of the H19-miR-93-ATG7 axis in tumor growth and DA treatment of pituitary tumors,which may be a potential therapeutic target for human pituitary tumors..

关键词： lncRNA H19 pituitary tumor miRNA-93 ATG7

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：