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Ectopic peritoneal paragonimiasis mimicking tuberculous peritonitis:A care report

World Journal of Clinical Cases 2022年第16期10卷 5359-5364页

作者： Jung Woo Choi Chang Min Lee Seong Je Kim Se In Hah Ji Yoon Kwak Hyun Chin Cho Chang Yoon Ha Woon Tae Jung Ok Jae Lee Department of Internal Medicine Gyeongsang National University College of Medicine and Gyeongsang National University HospitalJinju 52727South Korea Institute of Health Sciences Gyeongsang National UniversityJinju 52828South Korea

BACKGROUND The most common site of paragonimiasis is in the *** migratory route passes through the duodenal wall,peritoneum,and diaphragm to the lungs;thus,the thoracic cavity and central nervous system,as well as the liver,intestine,and abdominal cavity may be ***,we present a case of intraperitoneal paragonimiasis without other organ involvement,mimicking tuberculous *** SUMMARY A 57-year-old man presented with recurrent abdominal pain for 4 *** examination revealed tenderness in the right lower *** findings showed complete blood counts within the normal range without *** reactive lymph nodes and diffuse peritoneal infiltration were noted on abdominal computed tomography(CT).There were no abnormalities on chest CT or *** findings of diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis included multiple small whitish nodules and an abscess in the *** reports confirmed the presence of numerous eggs of Paragonimus westermani(***).A postoperative serum enzyme-linked immunosorbent assay revealed *** *** and repetitive history-taking led him to retrospectively recall the consumption of freshwater *** 3 d of treatment with praziquantel(1800 mg;25 mg/kg),he recovered from all *** In patients who require diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis,repetitive history-taking and preoperative serologic antibody tests against Paragonimus may be helpful in diagnosing intraperitoneal paragonimiasis without other organ involvement.

关键词： Differential diagnoses Intraperitoneal abscess paragonimiasis Paragonimus westermani Peritonitis Tuberculosis Case report

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Estimation of disability weight for paragonimiasis:a systematic analysis

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Infectious Diseases of Poverty 2018年第1期7卷 1163-1171页

作者： Yun Feng Thomas Fürst Lu Liu Guo-Jing Yang Jiangsu Institute of Parasitic Diseases 117 Meiyuan YangxiangWuxi CityJiangsu Province 214064People’s Republic of China Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention WuxiPeople’s Republic of China Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology WuxiPeople’s Republic of China Department of Epidemiology and Public Health Swiss Tropical and Public Health InstituteSocinstrasse 57CH-4002 BaselSwitzerland University of Basel BaselSwitzerland

Background:paragonimiasis,caused by helminths of the genus Paragonimus spp.,is a neglected tropical *** suffering from paragonimiasis is often misunderstood and its quantification by the disability weight of the disability-adjusted life years largely varies in different global burden of disease(GBD)*** paper is to systematically review clinical paragonimiasis cases and requantify the disability weight of human ***:A systematic analysis was conducted using articles from the following databases:PubMed,Institute for Scientific Information Web of Science,China National Knowledge Infrastructure,the Chinese scientific journal databases Wanfang Data and CQVIP,Africa Journal Online,and the System for Information on Grey Literature in *** terms were the combination of“paragonim*”with“clinical”or“infection”.Only articles fulfilling the following conditions were recruited for this study:the occurrence of clinical signs and symptoms of paragonimiasis in human beings were reported;diagnosis was confirmed;no comorbidities were reported;the reviewed clinical cases or epidemiological findings were not already included in any other *** information and frequencies of paragonimiasis outcomes from included articles using predefined data fields were extracted two times by two separate *** disability weights were selected mainly from the GBD 2004 and GBD 2013 *** and disability weights of paragonimiasis outcomes were modelled into a decision tree using the additive approach and multiplicative approach,*** Carlo simulations were run 5000 times for an uncertainty ***:The disability weight estimates of paragonimiasis were simulated with 5302 clinical cases from 80 general *** overall disability weight was estimated at 0.1927(median 0.1956)with a 95%uncertainty interval(UI)of 0.1632-0.2378 using the additive approach,and 0.1791(median 0.1816)with a 95%UI of 0.1530-

关键词： paragonimiasis Disability weight Disease burden Disability-adjusted life years

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Contrast-enhanced ultrasonographic findings of hepatic paragonimiasis

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World Journal of Gastroenterology 2013年第13期19卷 2087-2091页

作者： Qiang Lu Wen-Wu Ling Lin Ma Zi-Xing Huang Chang-Li Lu Yan Luo Department of Ultrasound Chinese Evidence-Based Medicine CenterWest China Hospital of Sichuan University Department of Ultrasound West China Hospital of Sichuan University Sichuan University Department of Radiology West China Hospital of Sichuan University Department of Pathology West China Hospital of Sichuan University

AIM: To investigate the features of hepatic paragonimiasis on contrast-enhanced ultrasound (CEUS) imag- ing. METHODS: Fifteen patients with hepatic paragonimiasis who were admitted to our hospital between March 2008 and August 2012 were enrolled to this study. The conventional ultrasound and CEUS examinations were performed with a Philips IU22 scanner with a 1-5-MHz convex transducer. After conventional ultrasound scanning was completed, the CEUS study was performed. Pulse inversion harmonic imaging was used for CEUS. A bolus injection of 2.4 mL of a sulfur hexafluoride-filled microbubble contrast agent (SonoVue) was administered. CEUS features were retrospectively reviewed and correlated with pathological findings. RESULTS: In total, 16 lesions were detected on CEUS. The mean size of the lesions was 4.4 ± 1.6 cm (range, 1.7-6.6 cm). Subcapsular location was found in 12 lesions (75%). All the lesions were hypoechoic. Six lesions (37.5%) were of mixed content, seven (43.8%) were solid with small cystic areas, and the other three (18.8%) were completely solid. Ten lesions (62.5%) were rim enhanced with irregular tract-like nonenhanced internal areas. Transient wedge-shaped hyperenhancement of the surrounding liver parenchyma was seen in seven lesions (43.8%). Areas with hyperor iso-enhancement in the arterial phase showed contrast wash-out and appeared hypoenhanced in the late phase. The main pathological findings included: (1) coagulative or liquefactive necrosis within the lesion, infiltration of a large number of eosinophils with the formation of chronic eosinophilic abscesses and sporadic distribution of Charcot-Leyden crystals; and (2) hyperplasia of granulomatous and fibrous tissue around the lesion. CONCLUSION: Subcapsular location, hypoechogenicity, rim enhancement and tract-like nonenhanced areas could be seen as the main CEUS features of hepatic paragonimiasis.

关键词： paragonimiasis Liver Infection Contrastenhanced ultrasonography

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赣东北与赣南5县1市并殖吸虫病流行状况的调查

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中国寄生虫学与寄生虫病杂志 1991年第S1期9卷 51-53页

作者：陈红根周宪民张少荣彭卫东汪维周袁建华曾小军江西省寄生虫病研究所江西医学院寄生虫学教研室

本文报道赣东北与赣南5县1市并殖吸虫的流行情况。用皮内试验检查1182人,阳性者140例,阳性率为11.8％。其中多数为弱阳性反应,占90.7％;仅9.3％为强阳性。贵溪县、戈阳县、安远县、上犹县、信丰县和景德镇市的阳性率分别为15.3％、7％、... 详细信息

本文报道赣东北与赣南5县1市并殖吸虫的流行情况。用皮内试验检查1182人,阳性者140例,阳性率为11.8％。其中多数为弱阳性反应,占90.7％;仅9.3％为强阳性。贵溪县、戈阳县、安远县、上犹县、信丰县和景德镇市的阳性率分别为15.3％、7％、15.9％,12.6％,12.1％和7.2％。上述5县1市溪蟹阳性率依次为42％、64.6％、60％、18.1％、32.9％和0。所检获的囊蚴经鉴定有卫氏井殖吸虫、斯氏狸殖吸虫和三平正并殖吸虫。

关键词： paragonimiasis epidemiological investigation Jiangxi.

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STUDIES ON SPECIFIC SEROLOGICAL ANTIGENS IN METACERCARIAE AND JUVENILES OF Paragoniums westermani AND ITS MONOCLONAL ANTIBODIES

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Science China Chemistry 1990年第2期33卷 178-187页

作者：蒋作君沈一平赵慰先 Nanjing Medical College Nanking 210005 PRC

The polyclonal antibodies to juveniles of Paragoniums westermani (PwJ-PcAbs) from sera of Wistar rats infected with Paragoniums westerrnani (P. w.)were purified by Sephadex G 200 chromatography. Next the shared serological antigens of P. w. metacercaria and juveniles (PwMJ-SAg) from the crude antigens of the metacercariae (M-NS-Ag) were purified with immuno-affinity chromatography on cyanogen bromide-activated cross-linked Sepharose 4B beads coupled withPwJ-PcAbs. PwMJ-SAg, agroup of glycoprotein molecules shown by the staining test, were specific serological antigens of P. w. metacercariae and juveniles, identified by the immunoabsorb test and immunoelectrophoresis. By SDSPAGE, PwMJ-SAg were fractionated to seven bands, including major bands A(***) and Bi(19.5 K), the two major serological antigen molecules. 20 sera samples from the patients with the nonpulmonary type of P. w. paragonimiasis were detected using PwMJ-SAg and M-NS-Ag by Dot-ELISA, and the difference of sensitivity between two

关键词： paragonimiasis serological antigens monoclonal antibodies diagnosis.

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Simultaneous Paragonimus infection involving the breast and lung:A case report

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World Journal of Clinical Cases 2019年第24期7卷 4292-4298页

作者： Moon Young Oh Ajung Chu Jeong Hwan Park Jong Yoon Lee Eun Youn Roh Young Jun Chai Ki-Tae Hwang Department of Surgery Seoul National University HospitalSeoul 156707South Korea Department of Radiology Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 156707South Korea Department of Pathology Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 156707South Korea Department of Laboratory Medicine Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 156707South Korea Department of Surgery Seoul Metropolitan Government Seoul National University Boramae Medical CenterSeoul 156707South Korea

BACKGROUND paragonimiasis is a food-borne parasitic infection caused by lung flukes of the genus Paragonimus. Although the most common site of infection is the pleuropulmonary area, the parasite can also reach other parts of the body on its journey from the intestines to the lungs, ending up in locations such as the brain,abdomen, skin, and subcutaneous tissues. Ectopic paragonimiasis is difficult to diagnose due to the rarity of this *** SUMMARY Here, we report a rare case of simultaneous breast and pulmonary paragonimiasis in a woman presenting painless breast mass and lung nodule with a history of eating raw trout. To confirm the diagnosis, serologic testing and tissue confirmation of the breast mass were performed. The patient was treated with surgical resection of the mass and praziquantel *** Ectopic paragonimiasis is difficult to diagnose due to the rarity of this ***, thorough history-taking and clinical suspicion of parasitic infection are important.

关键词： paragonimiasis Paragonimus westermani Parasitic infection Breast mass Lung nodule Case report

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血吸虫病与大肠癌关系的探讨

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寄生虫病与感染性疾病 1994年第3期2卷 46-47页

作者：郭霖周国兴湖南中医药学校成都卫生学校

血吸虫病与大肠癌关系的探讨成都卫生学校成都６１００１５郭霖湖南中医药学校株洲周国兴自１９８９年日本学者金森首次报道血吸虫病合并大肠癌以来，有关血吸虫病与大肠癌的关系已从多个角度进行了探讨。相当一部分学者认为二者之间有... 详细信息

血吸虫病与大肠癌关系的探讨成都卫生学校成都６１００１５郭霖湖南中医药学校株洲周国兴自１９８９年日本学者金森首次报道血吸虫病合并大肠癌以来，有关血吸虫病与大肠癌的关系已从多个角度进行了探讨。相当一部分学者认为二者之间有因果关系；但也有一部分学者认为二者...

关键词： paragonimiasis host Sichuan

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儿童肺吸虫病32例临床分析

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牡丹江医学院学报 1988年第1期 32-34页

作者：于萍牡丹江医学院附属三院儿科

肺吸虫病是由于肺吸虫寄生于人体所致的一种慢性地方性寄生虫病。人食用含有肺吸虫活囊蚴的生或半生的蟹、蝲蛄或饮用被污染的水而感染。临床常以嗜酸细胞增多及异位症状为主要表现。现将我科1979～1986年间收治的32例分析如下。临床资... 详细信息

肺吸虫病是由于肺吸虫寄生于人体所致的一种慢性地方性寄生虫病。人食用含有肺吸虫活囊蚴的生或半生的蟹、蝲蛄或饮用被污染的水而感染。临床常以嗜酸细胞增多及异位症状为主要表现。现将我科1979～1986年间收治的32例分析如下。临床资料本组男27例(84.4％),女5例(15.6％),男:女为5.4:1。4～6岁5例(15.6％),7～10岁23例(71.8％),11～14岁4例(12.5％),其中最小年龄为4岁,学龄期

关键词： paragonimiasis Bithionolum Praziquantelum

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