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Factors influencing further vertebral height loss following percutaneous vertebroplasty in osteoporotic vertebral compression fractures:A 1-year follow-up study

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World Journal of Clinical Cases 2024年第21期12卷 4609-4617页

作者： Zhong-Qiu Tang Shao-Bo He Dong-Yang Yu Hai-Mao Luo Xue-Hong Xing Yong-Wen Zhou Department of Spinal Surgery Affiliated Hospital of Panzhihua UniversityPanzhihua 617000Sichuan ProvinceChina Department of Shoulder and Elbow Surgery Affiliated Hospital of Panzhihua UniversityPanzhihua 617000Sichuan ProvinceChina

BACKGROUND osteoporotic vertebral compression fractures(OVCFs)contribute to back pain and functional limitations in older individuals,with percutaneous vertebroplasty(PVP)emerging as a minimally invasive ***,further height loss post-PVP prompts investigation into contributing *** To investigate the factors associated with further height loss following PVP with cement augmentation in OVCF *** A total of 200 OVCF patients who underwent successful PVP between January 2021 and December 2022 were included in this study.“Further height loss”during 1 year of follow-up in OVCF patients with bone edema was defined as a vertical height loss of≥4 *** study population was divided into two groups for analysis:The“No Further Height Loss group(n=179)”and the“Further Height Loss group(n=21).”RESULTS In comparing two distinct groups of patients,significant differences existed in bone mineral density(BMD),vertebral compression degree,prevalence of intravertebral cleft(IVF),type of bone cement used,and cement distribution *** from binary univariate regression analysis revealed that lower BMD,the presence of IVF,cleft distribution of bone cement,and higher vertebral compression degree were all significantly associated with further height ***,the use of mineralized collagen modified-poly(methyl methacrylate)bone cement was associated with a significant reduction in the risk of further height *** multivariate regression analysis,lower BMD and the presence of IVF remained significantly associated with further height *** Further height loss following PVP in OVCF patients is influenced by a complex interplay of factors,especially lower BMD and the presence of *** findings underscore the importance of assessing and managing these factors when addressing height loss following PVP in OVCF patients.

关键词： Percutaneous vertebroplasty osteoporotic vertebral compression fractures Further height loss Bone mineral density Intravertebral cleft

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Managements of osteoporotic vertebral compression fractures:A narrative review

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World Journal of Orthopedics 2022年第6期13卷 564-573页

作者： Devon Patel Jiayong Liu Nabil A Ebraheim College of Medicine and Life Sciences University of ToledoToledoOH 43614United States Department of Orthopedic Surgery University of Toledo Medical CenterToledoOH 43614United States

osteoporotic vertebral compression fractures(OVCFs)are the most common fragility fracture and significantly influence the quality of life in the ***,the literature lacks a comprehensive narrative review of the management of *** purpose of this study is to review background information,diagnosis,and surgical and non-surgical management of the OVCFs.A comprehensive search of PubMed and Google Scholar for articles in the English language between 1980 and 2021 was *** of the following terms were used:compression fractures,vertebral compression fractures,osteoporosis,osteoporotic compression fractures,vertebroplasty,kyphoplasty,bisphosphonates,calcitonin,and osteoporosis *** articles were also included by examining the reference list of articles found in the ***,especially those that occur over long periods,can be *** of acute OVCFs include pain localized to the mid-line spine,a loss in height,and decreased *** primary treatment regimens are pain control,medication management,vertebral augmentation,and anterior or posterior decompression and *** control can be achieved with acetaminophen or nonsteroidal anti-inflammatory drugs for mild pain or opioids and/or calcitonin for moderate to severe *** and denosumab are the first-line treatments for *** and kyphoplasty are reserved for patients who have not found symptomatic relief through conservative methods and are effective in achieving pain *** is less technical and cheaper than kyphoplasty but could have more *** and vitamin D supplementation can have a protective and therapeutic *** of OVCFs must be combined with multiple *** exercises and activity modification are important in fracture *** with different mechanisms of action is a critical long-term causal treatment *** minimall

关键词： vertebral body Osteoporosis Fragility fractures osteoporotic vertebral compression fractures Kyphoplasty Vertebroplasty

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Diagnosis and Treatment and Infection Protection Strategy of osteoporotic vertebral compression fractures Minimally Invasive Percutaneous Kyphoplasty Surgery during the Prevention and Control of COVID-19

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Surgical Science 2022年第12期13卷 541-550页

作者： Xinming Yang Chaowei Yang Lixing Chen Yao Yao Ye Tian Yupeng Sun The First Affiliated Hospital of Hebei North University Zhangjiakou China Graduate School of Hebei North University Zhangjiakou China

Background: As the global novel coronavirus pneumonia (NCP) remains severe, elderly people are at high risk for NCP and osteoporotic vertebral compression fractures, with high complications and mortality. How to treat patients and protect medical staff from infection, and at the same time strictly prevent the occurrence of clustered transmission events in the hospital, the establishment of perfect pre-hospital emergency measures and infection prevention and control strategy is the first element to ensure success. Objective: To establish the diagnosis and treatment and infection protection strategy for osteoporotic vertebral compression fractures (OVCF) patients undergoing minimally invasive percutaneous kyphoplasty (PKP) surgery during the prevention and control of COVID-19, so as to ensure the stable, orderly and safe medical treatment. Methods: A total of 583 OVCF patients were admitted to the First Affiliated Hospital of Hebei North University during the epidemic prevention and control period from January 2020 to July 2022. After urgent and outpatient strict standardized screening, 382 patients met the inclusion criteria, including 112 males and 270 females, aged (70.50 ± 5.49) years. The preoperative visual analogue scale (VAS) score was 6.92 ± 1.86. Preoperative Oswestry disability index (ODI) was 74.67 ± 4.84. The satisfaction rate was (45.89 ± 3.67) %. According to the clinical diagnostic criteria and classification, 367 patients were diagnosed as ordinary OVCF, including 156 cases of mild compression and 226 cases of moderate compression. The clinical classification of 15 patients with OVCF diagnosed as COVID-19 was type I, including 10 cases of mild COVID-19 and 5 cases of common COVID-19. All patients were treated with PKP. Results: All patients were followed up at 1 day, 1 month and 3 months after operation, VAS (2.01 ± 0.56, 0.45 ± 0.11, 0 ± 0), ODI (45.41 ± 4.15, 10.22 ± 2.73, 4.03 ± 1.57) and satisfaction (90.12%, 95.57%, 99.23%) were significantly imp

关键词： COVID-19 osteoporotic vertebral compression fractures Diagnosis and Treatment Percutaneous Kyphoplasty Operating Room Management Infection Protection

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Pedicle Screw Fixation with Kyphoplasty Decreases the Fracture Risk of the Treated and Adjacent Non-treated vertebral Bodies:a Finite Element Analysis

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2016年第6期36卷 887-894页

作者：杨攀章莹丁焕文刘坚叶林强肖进涂强杨涛王非孙国刚 Orthopedic Hospital Guangzhou General Hospital of People’s Liberation Army Department of Orthopedics Chongqing Traditional Chinese Medicine Hospital (the First People's Hospital of Chongqing) Department of Spinal Surgery the First Affiliated Hospital of Guangzhou University of Chinese Medicine Department of Anatomy Southwest Medical University

Adjacent vertebral fractures are common in patients with osteoporotic vertebral compression fractures（OVCFs） after *** finite element study was to examine whether short segment pedicle screw fixation（PSF） with kyphoplasty may decrease the fracture risk of the treated and adjacent non-treated vertebrae after kyphoplasty for *** simulating cement augmentation with or without short segment pedicle screw fixation（PSF）,two tridimensional,anatomically detailed finite element models of the T10–L2 functional spinal junction were *** insertion of pedicle screws into the intact vertebra apparently decreased the stress distribution of the treated vertebra in vertical compression and other load *** stress distribution in the bone structures of the intact vertebra adjacent to the intact-screwed vertebra was much less than that in the one adjacent to the treated *** insertion of pedicle screws into the intact vertebra greatly decreased the maximum displacement of the cortical bones and cancellous bones of the *** results indicated that short segment PSF with kyphoplasty may decrease the fracture risk of the treated and adjacent non-treated vertebrae in the management of OVCFs.

关键词： finite element analysis osteoporotic vertebral compression fractures kyphoplasty biomechanics pedicle screw fixation

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Application of PMMA bone cement composited with bone-mineralized collagen in percutaneous kyphoplasty

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Regenerative Biomaterials 2017年第4期4卷 251-255页

作者： Ming Bai Heping Yin Jian Zhao Yang Li Yongdong Yang Yimin Wu Department of Minimally Invasive Spinal Surgery of the Second Affiliated Hospital of Inner Mongolia Medical University Hohhot 010030China Inner Mongolia Medical University Hohhot 010030China Institute for Regenerative Biomaterials Tsinghua UniversityBeijing 100084China

We investigated the feasibility of applying polymethylmethacrylate bone cement composited with biomimetic bone-mineralizsed collagen to percutaneous kyphoplasty(PKP).We performed PKP in 95 patients diagnosed with osteoporotic vertebral compression *** patients had fractures of a single vertebral body,and they were divided randomly into control(group A,47 patients)and experimental(group B,48 patients)*** in group A were treated with acrylic cement,and those in group B were treated with acrylic cement composited with the bone graft *** patients were evaluated by a visual analogue scale(VAS),Oswestry disability index(ODI),Cobb angle and anterior vertebral body height preoperatively,and 3 days and 3 months *** patients successfully completed surgery and were followed up *** VAS score,ODI index,Cobb angle and anterior vertebral body height compression rate in both groups had significant changes(P0.05).The analgesic effects of bone cement composited with bone-mineralized collagen are similar to those of bone cement *** collagen has excellent promotion prospects by inducing new bone formation and reducing the incidence of adverse reactions caused by bone cement.

关键词： percutaneous kyphoplasty osteoporotic vertebral compression fractures bone cement mineralized collagen

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A method of percutaneous vertebroplasty under the guidance of two C-arm fluoroscopes

A method of percutaneous vertebroplasty under the guidance o...

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2016年浙江省骨科学学术年会

作者： Ren-Jie Xu Yong-Qing Yan Guang-Xiang Chen Tian-Ming Zou Xiao-Qiang Cai Dong-Lai Wang

Objective:To compare the clinical application in the percutaneous vertebroplasty under the guidance ofone or two C-arm ***:One hundred forty three elderly patients with osteoporotic vertebral compression fractures(OVCFs) underwent percutaneous vertebroplasty under the guidance of one or two C-arm *** number of pulsed imagings,the time of operation and the incidence of cement leakage were ***:The average number of pulsed imagings was 16.00±1.58 vs 13.07±2.00 per patient under theguidance of one vs two C-arm *** average time of operation was 48.42±5.00 minutes vs39.70±7.42 minutes per patient under the guidance of one vs two C-arm *** incidenceof cement leakage was 20%vs 15.7%of the patients under the guidance of one vs two C-arm *** differences in the number of pulsed imagings and the time of operation were statistically *** difference in incidence of cement leakage was not statistically ***:The two-fluoroscopic technique reduce the labor cost,the radiation,the time of operationand the operation risk.

关键词： osteoporotic vertebral compression fractures Percutaneous vertebroplasty Two C-arm fluoroscopes

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A method of percutaneous vertebroplasty under the guidance of two C-arm fluoroscopes

A method of percutaneous vertebroplasty under the guidance o...

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2015年浙江省骨科学学术年会

作者： Ren-Jie Xu Yong-Qing Yan Guang-Xiang Chen Tian-Ming Zou Xiao-Qiang Cai Dong-Lai Wang

Objective:To compare the clinical application in the percutaneous vertebroplasty under the guidance of one or two C-arm ***:One hundred forty three elderly patients with osteoporotic vertebral compression fractures(OVCFs)underwent percutaneous vertebroplasty under the guidance of one or two C-arm *** number of pulsed imagings,the time of operation and the incidence of cement leakage were ***:The average number of pulsed imagings was 16.00±1.58 vs 13.07±2.00 per patient under the guidance of one vs two C-arm *** average time of operation was 48.42±5.00 minutes vs 39.70±7.42 minutes per patient under the guidance of one vs two C-arm *** incidence of cement leakage was 20%vs 15.7%of the patients under the guidance of one vs two C-arm *** differences in the number of pulsed imagings and the time of operation were statistically *** difference in incidence of cement leakage was not statistically ***:The two-fluoroscopic technique reduce the labor cost,the radiation,the time of operation and the operation risk.

关键词： osteoporotic vertebral compression fractures Percutaneous vertebroplasty Two C-arm fluoroscopes

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